각막궤양에서 양막이식술 후 발생한 각막혼탁 감소를 위한 각막문신 = Corneal Tattooing to Mask the Opacification after Amniotic Membrane Grafting for Corneal Ulcer

다국어 초록 (Multilingual Abstract)

Purpose: To report on the cosmetic efficacy of corneal tattooing using India ink in cases where amniotic membrane grafting was performed to promote corneal wound healing in corneal ulcers. Methods: Amniotic membrane grafting of corneal ulcers was carried out in three patients with no expectation of visual recovery. After corneal reepithelization, a 30 G needle filled with India ink was placed into the amniotic membrane space between the regenerated corneal epithelium and the stromal bed, and the ink was then carefully injected. Results: The staining of corneas to the appropriate opacity with India ink was successful in all cases. There were no significant complications during the mean follow up period of 17 months. All the patients were well satisfied with the corneal staining. Conclusions: When corneal opacity occurs subsequent to an amniotic membrane graft for a corneal ulcer, this corneal tattooing with an intrastromal injection of India ink into the amniotic membrane space might be a very useful method to achieve a good cosmetic result.

참고문헌 (Reference)

1 Leigh AG, "Tattooing of the cornea Systemic of Ophthalmology" Henry Kimpton 1965 645-8,

2 Pickrell KL, "Tattoing of corneal scars with insoluble pigments" 2 : 33-59, 1947

3 Rodriguez-Ares MT, "Multulayer Amniotic membrane transplantation in the treatment of corneal perforation" 23 : 577-583, 2004

4 Sekundo W, "Long term ultrastructural changes in human corneas after tattooing with non-metallic substances" 83 : 219-224, 1999

5 Mannis MJ, "Keratopigmentation:A review of corneal tattooing" 18 : 633-637, 1999

6 Kim CO, "Cosmetic repairing of corneal opacity by tattooing" 46 : 1967-1974, 2005

7 Meller D, "Conjunctival epithelial cell differentiation on amniotic membrane" 40 : 878-886, 1999

8 Olander K, "An analytical electron microscopic study of a corneal tattoo" 15 : 1046-9, 1983

9 Chen HJ, "Amniotic membrane transplantation for severe neurotrophic corneal ulcers" 84 : 826-833, 2000

10 Lee SH, "Amniotic membrane transplantation for persistent epithelial defects with ulceration" 123 : 303-312, 1997

11 Azuara-Blanco A, "Amniotic membrane transplantation for ocular surface reconstruction" 83 : 399-402, 1999

12 Tseng SCG, "Amniotic membrane transplantation for conjunctival surface reconstruction" 124 : 765-774, 1997