Skin Diseases in Patients with Primary Psychiatric Disorders

다국어 초록 (Multilingual Abstract)

Objective The few psychodermatological studies of primary psychiatric populations so far suggest that parasitic-infectious skin diseases are the most common dermatological comorbidity in more than 70% of psychiatric patients, which should be studied here in a large data bank outside dermatological treatment facilities.
Methods In a descriptive-explorative and retrospective study, more than 17,000 patients with primary psychiatric disorders were examined to investigate dermatological comorbidities.
Results The proportion of patients with primary mental disorders and additional dermatological disease was 1.24% (n=212). Here, psoriasis (35.4%) and atopic dermatitis (22.6%) were the most frequent dermatological diseases among these 212 patients. Infectiousparasitic skin diseases were present in 13.2% of comorbid patients. The most common mental disorder was a depressive illness, seen in 42.5% (n=90) of patients.
Conclusion Our results confirmed the frequent association of depression with psoriasis and atopic dermatitis, indicating the need for the early detection and treatment of such comorbid patients. In contrast, psychiatric inpatients do not appear to suffer from predominantly infectious-parasitic dermatoses.

참고문헌 (Reference)

1 Marshall VD, "apropensity-matched case control study" 6 : 649-658, 2016

2 Saxton KB, "The social environment and IL-6 in rats and humans" 25 : 1617-1625, 2011

3 Kurd SK, "The risk of depression, anxiety, and suicidality in patients with psoriasis : a populationbased cohort study" 146 : 891-895, 2010

4 Dalgard FJ, "The psychological burden of skin diseases : a cross-sectional multicenter study among dermatological out patients in 13 European countries" 135 : 984-991, 2015

5 Gupta AK, "The prevalence of unsuspected onychomycosis and its causative organisms in a multicentre Canadian sample of 30000 patients visiting physicians’ offices" 30 : 1567-1572, 2016

6 Dowlatshahi EA, "The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients : a systematic review and meta-analysis" 134 : 1542-1551, 2014

7 Dieris-Hirche J, "Suicidal ideation, anxiety and depression in adult patients with atopic dermatitis" 60 : 641-646, 2009

8 Dieris-Hirche J, "Suicidal ideation in adult patients with atopic dermatitis : a German cross-sectional study" 97 : 1189-1195, 2017

9 Topic R, "Somatic comorbidity, metabolic syndrome, cardiovascular risk, and CRP in patients with recurrent depressive disorders" 54 : 453-459, 2013

10 Mookhoeck EJ, "Skin disorders in chronic psychiatric illness" 24 : 1151-1156, 2010

11 Moftah NH, "Skin diseases in patients with primary psychiatric conditions : a hospital based study" 3 : 131-138, 2013

12 Bai F, "Serum levels of adipokines and cytokines in psoriasis patients : a systematic review and meta-analysis" 9 : 1266-1278, 2017

13 Cvetkovski RS, "Quality of life and depression in a population of occupational hand eczema patients" 54 : 106-111, 2006

14 Chagon A, "Psychosocial impact of onychomycosis : a review" 52 : 1300-1307, 2013

15 Lee SH, "Psychological health status and health-related quality of life in adults with atopic dermatitis. A nationwide cross-sectional study in South Korea" 98 : 89-97, 2018

16 Brown GE, "Psychodermatology" 34 : 123-134, 2015

17 Kuhn H, "Psychocutaneous disease : pharmacotherapy and psychotherapy" 76 : 795-808, 2017

18 Picardi A, "Psychiatric morbidity in dermatological outpatients : an issue to be recognized" 143 : 983-991, 2000

19 Nicholas MN, "Psoriasis, depression, and suicidality" 22 : 1-4, 2017

20 Hu SC, "Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment" 18 : pii: E2211-, 2017

21 Ferreira BR, "Psoriasis and associated psychiatric disorders : a systematic review on etiopathogenesis and clinical correlation" 9 : 36-43, 2016

22 Wu BY, "Prevalence and associated factors of comorbid skin diseases in patients with schizophrenia : a clinical survey and national health database study" 36 : 415-421, 2014

23 Sakka N, "Occult tinea pedis in an Israeli population and predisposing factors for the acquisition of the disease" 54 : 146-149, 2015

24 Ajdacic-Gross V, "Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders : results from a large Swiss epidemiological study" 6 : 419-430, 2016

25 Egeberg A, "Impact of depression on risk of myocardial infarction, stroke and cardiovascular death in patients with psoriasis : a Danish nationwide study" 96 : 218-221, 2016

26 Eckert L, "Impact of atopic dermatitis on health related quality of life and productivity in adults in the United States : an analysis using the National Health and Wellness Survey" 77 : 274-279, 2017

27 Kwak Y, "Health-related quality of life and mental health of adults with atopic dermatitis" 31 : 516-521, 2017

28 Mavrogiorgou P, "Erkrankungen der Haut bei primär psychischen Störungen" 84 : 608-616, 2016

29 Mavrogiorgou P, "Dermatologische Erkrankungen und ihre Bedeutung für die Psychiatrie" 88 : 254-267, 2017

30 Strober B, "Depressive symptoms, depression, and the effect of biologic therapy among patients in Psoriasis Longitudinal Assessment and Registry(PSOLAR)" 78 : 70-80, 2018

31 Bangemann K, "Depression und Angststörung bei Psoriasispatienten" 65 : 1056-1061, 2014

32 Onderdijik AJ, "Depression in patients with hidradenitis suppurativa" 27 : 473-478, 2013

33 Koo J, "Depression and suicidality in psoriasis : review of the literature including the cytokine theory of depression" 31 : 1999-2009, 2017

34 Nowak DA, "DSM-5 update in psychodermatology" 21 : 4-7, 2016

35 Gerdes S, "Comorbidity in psoriasis" 67 : 438-444, 2016

36 Tully PJ, "Comorbid anxiety disorders alter the association between cardiovascular diseases and depression : the German National Health Interview and Examination Survey" 49 : 683-691, 2014

37 Sanna L, "Atopic disorders and depression : findings from a large, population-based study" 155 : 261-265, 2014

38 Thyssen JP, "Atopic dermatitis is associated with anxiety, depression, and suicidal ideation, but not with psychiatric hospitalization or suicide" 73 : 214-220, 2018

39 Petraskiene R, "Associations of the quality of life and psychoemotional state with sociodemographic factors in patients with psoriasis" 52 : 238-243, 2016

40 Yu SH, "Association between atopic dermatitis and depression in US adults" 135 : 3183-3186, 2015

41 Boehm D, "Anxiety, depression and impaired-related quality of life in patients with occupational hand eczema" 67 : 184-192, 2012

42 Kawai M, "A retrospective cohort study of tinea pedis and tinea unguium in inpatients in a psychiatric hospital" 55 : E35-E41, 2014