In the prevention of Clonorchis the most inportant measure is to interrupt its life cycle. Destruction of the cercaria, one of the developing atages of the Clonorchis Sinensia may have an important role in the prevention of Clonorchis, Consequently an...
In the prevention of Clonorchis the most inportant measure is to interrupt its life cycle. Destruction of the cercaria, one of the developing atages of the Clonorchis Sinensia may have an important role in the prevention of Clonorchis, Consequently an attempt is made to evaluate the effect of the following substances in destroying the cercaria.
1) Disinfectants.
2) Acid and Alkali.
3) Antiprotozoae.
4) Seasonings.
5) Drugs commonly used for the treatment of Clonorohis.
1) Disinfectants:
The cercariae were killed within 30 minutes in the following Solutions.
1:1,280 cresol, 1:10,000 formalin and 1:5,120 sublimate.
2) Acid and Alkali:
The carcariae are quite fragile against acid and they were killed in 1:51,200 acetic acid within 40 minutes, in 1:76,800 hydrochloric acid within 38 minutes and in 1:32,000 Nitric acid within 14 minutes. They were also killed in relatively short period of time in various alkali solutions except for Sodium carbonate (NaHCO_3) solution.
3) Antiprotozoas and other drugs:
The cercariae are not sensitive to those substances. Among those Quinine has the most powerful effect in destroying the cercaria.
4) Seasonings:
The cercariae are fragile against the garlic and they were killed in 1:128 solutions within 28 minutes.
5) Drugs commonly used for the treatment of Clonorchis;
The cercariae were some what senesitive to Gentiana-violet but they were not sensitive to other drugs.