Subjective Cognitive Decline Patterns in Patients with Migraine, with or without Depression, versus Non-depressed Older Adults|RISS 상세보기

다국어 초록 (Multilingual Abstract)

Purpose: Cognitive decline is a common complaint in young patients with migraine, especially those with depression. Independent of psychiatric factors such as depression, subjective cognitive decline (SCD) is associated with an elevated risk of progression to dementia. This study aimed to investigate patterns of subjective cognitive complaints between migraineurs with or without depression and non-depressed older adults.Methods: This retrospective study included 331 outpatients with SCD (293 from a headache clinic and 38 from a memory clinic). SCD was diagnosed as “yes” based on two questions about SCD. The Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used to assess cognitive function. The SCD Questionnaire (SCD-Q) with three subdomains was analyzed to compare SCD between groups.Results: Among patients with SCD, significant differences in duration of education were found among the groups—specifically, migraineurs with depression (12.39 years) had longer education than non-depressed older adults (10.50 years) and shorter education than migraineurs without depression (14.28 years). The total MMSE and MoCA scores did not differ between migraineurs with and without depression. Regarding SCD-Q scores, migraineurs with depression showed higher scores overall and in all cognitive domains than migraineurs without depression, with no significant difference compared to non-depressed older adults. Conclusion: Although the depressed migraineurs with SCD were younger and more educated than the non-depressed older adults with SCD, both groups reported similarly high levels of SCD. Higher levels of surveillance for cognitive decline are warranted for migraineurs with depression who have SCD.

번역하기

참고문헌 (Reference)

1 Seo JG, "Validation of the Patient Health Questionnaire-9(PHQ-9)and PHQ-2 in patients with migraine" 16 : 65-, 2015

2 Cho MJ, "Validation of geriatric depression scale, Korean version(GDS)in the assessment of DSM-III-R major depression" 38 : 48-63, 1999

3 Rami L, "The subjective cognitive decline questionnaire(SCD-Q) : a validation study" 41 : 453-466, 2014

4 Jessen F, "The characterisation of subjective cognitive decline" 19 : 271-278, 2020

5 Headache Classification Committee of the International Headache Society(IHS), "The International Classification of Headache Disorders, 3rd edition" 38 : 1-211, 2018

6 Lee SH, "Subjective cognitive decline in patients with migraine and its relationship with depression, anxiety, and sleep quality" 18 : 77-, 2017

7 Rabin LA, "Subjective cognitive decline in older adults : an overview of self-report measures used across 19 international research studies" 48 (48): S63-, 2015

8 Ali JI, "Subjective cognitive decline and APOE ɛ4 : a systematic review" 65 : 303-320, 2018

9 Amariglio RE, "Subjective cognitive complaints and amyloid burden in cognitively normal older individuals" 50 : 2880-2886, 2012

10 Kang Y, "Seoul Neuropsychological Screening Battery (SNSB)" Human Brain Research & Consulting Co 2012