Cancer Morbidity of Foundry Workers in Korea

다국어 초록 (Multilingual Abstract)

Foundry workers are potentially exposed to a number of carcinogens. This study was conducted to describe the cancer incidence associated with employment in small-sized Korean iron foundries and to compare those findings to the Korean population. Cancer morbidity in 208 Korean foundries was analyzed using the Standardized Incidence Ratio (SIR) and Standardized Rate Ratio (SRR). Overall cancer morbidity in foundry workers (SIR=1.11, 95% confidence interval [CI]=1.01-1.21) was significantly higher than that of Korean general population. Lung cancer (SIR=1.45, 95%CI=1.11-1.87) and lymphohematopoietcic cancer (SIR=1.58, 95%CI=1.00-2.37) in production workers were significantly high compared to Korean general population. Stomach cancer in fettling (SRR=2.10, 95%CI=1.10-4.01) and lung cancer in molding (SRR=3.06, 95%CI=1.22-7.64) and in fettling (SRR=2.63, 95%CI=1.01-6.84) were there significant elevations compared to office workers. In this study, statistically significant excess lung cancer was observed in production workers comparing to Korean general population and office workers. Also, cancer morbidity of overall cancer, lung cancer and stomach cancer was significantly increased with duration of employment at ten and more years comparing to Korean general population. These findings suggest in causal association between exposure to carcinogens during foundry work and cancer morbidity.

참고문헌 (Reference)

1 박용선, "주물사업장에서 발생하는 호흡성분진의 농도 및 석영함유량에 관한 연구" 한국산업위생학회 13 (13): 90-97, 2003

2 임호섭, "자동차배기가스 검사소와 소각장 공기 중 PAHs의 구성성분 및 근무자들의 요중 1-Hydroxypyrene과 2-Naphthol 평가" 한국산업위생학회 14 (14): 134-143, 2004

3 이종성, "다핵방향족탄화수소류에 노출된 페인트 취급 근로자에서 요 중 1-hydroxypyrene을 이용한 생물학적 모니터링" 한국산업위생학회 15 (15): 124-134, 2005

4 Baan R, "WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens. Part F: chemical agents and related occupations" 10 : 1143-1144, 2009

5 Ahn YS, "Understanding the occurrence of lung cancer in foundry workers through health insurance data" 33 : 299-305, 2000

6 Wartenberg D, "Trichloroethylene and cancer: epidemiologic evidence" 108 (108): 161-176, 2000

7 Korea National Statistical Office, "The number of registered population in Korea by gender and 5-year age group from 1992 to 2005"

8 Rotimi C, "Retrospective follow-up study of foundry and engine plant workers" 24 : 485-498, 1993

9 Ahn YS, "Respiratory diseases in foundry workers. In: Training materials for occupational respiratory diseases"

10 Porru S, "Primary liver cancer and occupation in men: a case-control study in a high-incidence area in Northern Italy" 94 : 878-883, 2001

11 Tolbert PE, "Oils and cancer" 8 : 386-405, 1997

12 Ji J, "Occupational risk factors for kidney cancer: a cohort study in Sweden" 23 : 271-278, 2005

13 Brown DA, "Motor vehicle manufacturing and prostate cancer" 38 : 59-70, 2000

14 Koskela RS, "Mortality, morbidity and health selection among metal workers" 23 (23): 1-80, 1997

15 Hoshuyama T, "Mortality of iron-steel workers in Anshan, China: a retrospective cohort study" 12 : 193-202, 2006

16 Park RM, "Mortality at an automotive engine foundry and machining complex" 43 : 483-493, 2001

17 Silverstein M, "Mortality among ferrous foundry workers" 10 : 27-43, 1986

18 Sorahan T, "Mortality among a cohort of United Kingdom steel foundry workers with special reference to cancers of the stomach and lung, 1946-90" 51 : 316-322, 1994

19 IARC, "IARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans"

20 Adzersen KH, "Cancer mortality in a cohort of male German iron foundry workers" 43 : 295-305, 2003

21 Sorahan T, "Cancer mortality in a cohort of United Kingdom steel foundry workers: 1946-85" 46 : 74-81, 1989

22 Hansen ES, "Cancer mortality among Danish molders" 20 : 401-409, 1991

23 Ahn YS, "Cancer morbidity in iron and steel workers in Korea" 49 : 647-657, 2006

24 정규원, "Cancer Statistics in Korea: Incidence, Mortality and Survival in 2005" 대한의학회 24 (24): 995-1003, 2009

25 Kim HW, "Analysis of quartz contents by XRD and FTIR in respirable dust from various manufacturing industries part I-Foundry" 8 : 50-66, 1998

26 Phee YG, "Analysis of quartz content and particle size distribution of airborne dust from selected foundry operations" 7 : 196-208, 1997

27 Korea Association of Smoking and Health, "Adult smoking rate by the year. KASH"

28 Taeger D, "A stand-alone windows applications for computing exact person-years, standardized mortality ratios and confidence intervals in epidemiological studies" 11 : 607-608, 2000

29 Straif K, "A review of human carcinogens. Part C: metals, arsenic, dusts, and fibres" 10 : 453-454, 2009

30 Korea Ministry of Labor, "2001 Year Book of Health Examination Result of Workers"