호르몬 보충요법을 시행한 폐경여성에서 유방촬영 소견의 변화 = Mammographic Changes Associated with Postmenopausal Hormone Replacement Therapy

다국어 초록 (Multilingual Abstract)

I retrospectively analyzed the incidence and patterns of breast parenchymal changes of 133 follow-up mammograms in 115 postmenopausal women with hormone replacement therapy. And I also evaluated the correlations between the possible influencing factors to the mammographic changes(age, menopausal period, parenchymal pattern and duration of therapy) and incidence of parenchymal changes. Hormone replacement therapy was performed by cyclic sequntial therapy with estradiol valerate and norgestrel. The mean interval of follow-up studies was 13.7(±4.9) months.
The incidence of increase in parenchymal density after hormone replacement therapy was 27%(36/133). The patterns of increased parenchymal density were focal(22%) and diffuse(78%). None of them showed decrease in parenchymal density on the follow-up mammogram. There was no statistically significant correlation between the possible influencing factors and incidence of increase in breast parenchymal density, but the duration of therapy which showed differential tendency(p=0.07). In summary, 27% of 103 follow-up mammograms in 115 postmenopausal women with hormone replacement therapy showed increased breast parenchymal density. Therefore, careful consideration is needed in interpretation of follow-up mammogram in patients with hormone replacement therapy.