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      심부전증 환자의 12주간 운동이 CRP와 BNP에 미치는 영향 = Clinical Article : The Effect of 12-weeks Regular Exercise on CRP and BNP in Chronic Heart Failure

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      https://www.riss.kr/link?id=A76545401

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      다국어 초록 (Multilingual Abstract)

      The purpose of this study was for analysis of CRP & BNP change of CHF (Congestive Heart Failure) patients according to exercise. Thirty patients with CHF (EF<40%) participated in this study. The subjects were randomly assigned to three groups; supe...

      The purpose of this study was for analysis of CRP & BNP change of CHF (Congestive Heart Failure) patients according to exercise. Thirty patients with CHF (EF<40%) participated in this study. The subjects were randomly assigned to three groups; supervised exercise group(SEG, n=10), home-based exercise group (HEG, n=10), control group (CG, n=10). Patients in SEG exercised in medical center, and patients in HEG exercised in home or local health center. Exercise intensity was 60%HRR or 60%O2R. In that result, it was shown that CRP was significant difference among three groups. CG was increased than other groups (p<0.05). But BNP was not significant difference among three groups. However, HEG was decreased significantly after exercise (p<0.05). In conclusion, the results demonstrated that regular exercise improved inflammation marker in CHF patients.

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      참고문헌 (Reference)

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      2 Rohde LE, "Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men" 84 (84): 1018-1022, 1999

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      4 Munford RS, "Statina and the acute-phase response" 344 : 2016-2018, 2001

      5 Barinas-Mitchell E, "Serum levels of C-reactive protein are associated with obesity, weight, gain, and hormone replacement therapy in healthy postmenopausal women" 153 : 1094-1101, 2001

      6 Pietila KO, "Serum C-reactive protein concentrations in acute myocardial infarction and its relationship to mortality during 24 months of followup in patients under thrombolytic treatment" 17 : 1345-1349, 1996

      7 Sato Y, "Serial circulating concentrations of C-reactive protein, interleukin(IL)-4, and IL-6 in patients with acute left heart decompensation" 22 : 811-813, 1999

      8 Steele IC, "Responses of atrial natriuretic peptide and brain natriuretic peptide to exercise in patients with chronic heart failure and normal control subjects" 27 (27): 270-276, 1997

      9 Friedl W, "Relationship between natriuretic peptides and hemodynamics in patients with heart failure at rest and after ergometric exercise" 281 (281): 121-126, 1999

      10 Mattusch F, "Reduction of the plasma concentration of C-reactive protein following nine months of endurance training" 21 (21): 21-24, 2000

      1 Akbartabartoori M, "The associations between current recommendation for physical activity and cardiovascular risks associated with obesity" 62 (62): 1-9, 2008

      2 Rohde LE, "Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men" 84 (84): 1018-1022, 1999

      3 Pye M, "Study of serum C-reactive protein concentration in cardiac failure" 63 : 228-230, 1990

      4 Munford RS, "Statina and the acute-phase response" 344 : 2016-2018, 2001

      5 Barinas-Mitchell E, "Serum levels of C-reactive protein are associated with obesity, weight, gain, and hormone replacement therapy in healthy postmenopausal women" 153 : 1094-1101, 2001

      6 Pietila KO, "Serum C-reactive protein concentrations in acute myocardial infarction and its relationship to mortality during 24 months of followup in patients under thrombolytic treatment" 17 : 1345-1349, 1996

      7 Sato Y, "Serial circulating concentrations of C-reactive protein, interleukin(IL)-4, and IL-6 in patients with acute left heart decompensation" 22 : 811-813, 1999

      8 Steele IC, "Responses of atrial natriuretic peptide and brain natriuretic peptide to exercise in patients with chronic heart failure and normal control subjects" 27 (27): 270-276, 1997

      9 Friedl W, "Relationship between natriuretic peptides and hemodynamics in patients with heart failure at rest and after ergometric exercise" 281 (281): 121-126, 1999

      10 Mattusch F, "Reduction of the plasma concentration of C-reactive protein following nine months of endurance training" 21 (21): 21-24, 2000

      11 Milani RV, "Reduction in C-reactive protein through cardiac rehabilitation and exercise training" 43 (43): 1056-1061, 2004

      12 Kohno M, "Pulmonary arterial brain natriuretic peptide concentration and cardiopulmonary hemodynamics during exercise in patients with essential hypertension" 41 (41): 1273-1275, 1992

      13 Stauffer BL, "Plasma C-reactive protein is not elevated in physically active postmenopausal women taking hormone replacement therapy" 96 (96): 143-148, 2004

      14 Fried SK, "Omental and subcutaneous adipose tissues of obese subjects release interleukin-6" 83 : 847-850, 1998

      15 Bentzen H, "Influence of training habits on exercise-induced changes in plasma atrial and brain natriuretic peptide and urinary excretion of aquaporin-2 in healthy man" 62 (62): 541-551, 2002

      16 Rader D, "Inflammatory markers of coronary risk" 343 : 1179-1182, 2000

      17 Yousufuddin M, "Incremental importance of peak-exercise plasma levels of endothelin-1 and natriuretic peptides in chronic heart failure" 38 (38): 468-473, 2001

      18 Bonow RO, "Impaired left ventricular diastolic filling in patient with coronary artery disease assessment with radionuclide angiography" 64 : 315-323, 1981

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      20 Taylor J Marcell, "Exercise training is not associated improved levels of C-reactive protein or adiponectin" 54 : 533-541, 2005

      21 Fichtlscherer S, "Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease" 102 : 1000-1006, 2000

      22 Matsumoto A, "Effects of exercise on plasma level of brain natriuretic peptide in congestive heart failure with and without left ventricular dysfunction" 129 (129): 139-145, 1995

      23 Barletta G, "Effects of exercise on natriuretic peptides and cardiac function in man" 65 (65): 217-225, 1998

      24 Esposito K, "Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial" 289 (289): 1799-1804, 2003

      25 Bentzen H, "Effect of exercise on natriuretic peptides in plasma and urine in chronic heart failure" 93 (93): 121-130, 2004

      26 Pasceri V, "Direct proinflammatory effects if C-reactive protein on human endothelial cells" 102 : 2165-2168, 2000

      27 Bhakdi S, "Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation" 1 : 2348-2354, 1999

      28 Simon GW, "Comparison of plasma N-brain natriuretic peptide, peak oxygen consumption, and left ventricular ejection fraction for severity of chronic heart failure" 93 (93): 1560-1561, 2004

      29 Richard RL, "Cardiac output and oxygen release during very high-intensity exercise performed untile exhaustion" 93 (93): 9-18, 2004

      30 Zwaka TP, "C-reactive protein-mediated low density lipoprotein uptake by macrophases: implications for atherosclerosis" 103 : 1194-1197, 2001

      31 Torzewski M, "C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesis" 20 : 2094-2099, 2000

      32 Cook DG, "C-reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors" 149 : 139-150, 2000

      33 Ridker PM, "C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women" 342 : 836-843, 2000

      34 이현철, "C-reactive Protein과 대사성 증후군" 대한내분비학회 17 (17): 152-157, 2002

      35 Stefan Kruger, "Brain natriuretic peptide kinetics during dynamic exercise in patients with chronic heart failure" 95 : 49-54, 2003

      36 Rawson ES, "Body mass index, but not physical activity, is associated with C-reactive protein" 35 (35): 1160-1166, 2003

      37 Kato M, "Augmented response in plasma brain natriuretic peptide to dynamic exercise in patients with left ventricular dysfunction and congestive heart failure" 248 (248): 309-315, 2000

      38 Kijin Kim, "Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults" 57 : 1181-1189, 2008

      39 Hak AE, "Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women" 19 : 1986-1991, 1999

      40 Church TS, "Associations between cardiorespiratory fitness and Ccreative protein in men" 22 (22): 1869-1876, 2002

      41 Geffken DF, "Association between physical activity and markers of inflammation in a healthy elderly population" 153 (153): 242-250, 2001

      42 Ford ES, "A comparison of the metabolic syndrome using two proposed definitions" 26 : 575-581, 2003

      43 Yudkin JS, "-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?" 19 : 972-978, 1999

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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.32 0.32 0.29
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.24 0.23 0.525 0
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