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The cardiac effects of Phellinus linteus have been investigated on the isolated perfused guinea pig hearts maintained at the constant hydrostatic perfusion pressure of 80 ㎝ water. The effects of Phellinus linteus on ADP and PAF - induced platelet ag...
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RISS 인기검색어
상황(Phellinus linteus)의 Guinea pig 적출 심장에 대한 보호 작용 및 항혈소판응집 작용 = Protective Effects of Phellinus linteus on Reperfusion of the Isolated Perfused Guinea pig Hearts and Anti-platelet Aggregation Effects of Phellinus linteus
한글로보기https://www.riss.kr/link?id=A19590763
- 저자
- 발행기관
- 학술지명
- 권호사항
-
발행연도
1994
-
작성언어
Korean
-
KDC
518.000
-
자료형태
학술저널
-
수록면
17-25(9쪽)
- 제공처
- 소장기관
-
0
상세조회 -
0
다운로드
부가정보
다국어 초록 (Multilingual Abstract)
The cardiac effects of Phellinus linteus have been investigated on the isolated perfused guinea pig hearts maintained at the constant hydrostatic perfusion pressure of 80 ㎝ water. The effects of Phellinus linteus on ADP and PAF - induced platelet aggregation in vitro were also investigated. In ischemia-reperfusion experiments, Phellinus linteus showed negative inotropic effects by decreasing of LVP, LVDP, LV dp/dt and Rate Pressure Product, and also showed cardiac protective effect by increasing the coronary flow (CF) in the guinea pig heart. In platelet aggregation experiment, Phellinus linteus did not affect the ADP (5 μM) induced platelet aggregation, but reduced PAF (0.3 μM) induced aggregation by 26.03 ± 8.86% and 53.42 ± l2.36% at 1.0 ㎍/㎖ and 3.0 ㎍/㎖, respectively.
The cardiac effects of Phellinus linteus have been investigated on the isolated perfused guinea pig hearts maintained at the constant hydrostatic perfusion pressure of 80 ㎝ water. The effects of Phellinus linteus on ADP and PAF - induced platelet aggregation in vitro were also investigated. In ischemia-reperfusion experiments, Phellinus linteus showed negative inotropic effects by decreasing of LVP, LVDP, LV dp/dt and Rate Pressure Product, and also showed cardiac protective effect by increasing the coronary flow (CF) in the guinea pig heart. In platelet aggregation experiment, Phellinus linteus did not affect the ADP (5 μM) induced platelet aggregation, but reduced PAF (0.3 μM) induced aggregation by 26.03 ± 8.86% and 53.42 ± l2.36% at 1.0 ㎍/㎖ and 3.0 ㎍/㎖, respectively.
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