The butanol fraction from the bark of Aralia elata SEEM(Araliaceae) showed marked antitumor and cytotoxic activity. The solid tumor growth inhibition ratio of the BuOH fraction againse sarcoma-180 was at highest level of 74.15% while administrating in...
The butanol fraction from the bark of Aralia elata SEEM(Araliaceae) showed marked antitumor and cytotoxic activity. The solid tumor growth inhibition ratio of the BuOH fraction againse sarcoma-180 was at highest level of 74.15% while administrating in the concentration of 100mg/Kg/day and life prolongation ratio showed 52.75% in the concentration of 100mg/Kg/day. In incubation of sarcoma-180 tumor cell with BuOH fraction, viability was 15.73%, the direct cytotoxic activity of Aralia elata was remarked in vitro.
But the administered group being compared with the controlled group, no significant changes revealed in the immune reaction.