A 43-year-old man presented with dry cough and right chest pain. Chest X-ray showed normal and chest CT scan revealed thin-walled cysts of various sizes and nodules in both upper lobe. Abdominal CT scan revealed multiple low attenuated nodules in live...
A 43-year-old man presented with dry cough and right chest pain. Chest X-ray showed normal and chest CT scan revealed thin-walled cysts of various sizes and nodules in both upper lobe. Abdominal CT scan revealed multiple low attenuated nodules in liver and multiple abodominal lymph nodes enlargement. Liver biopsy was performed. Light microscopic examination revealed proliferation and infiltration of Langerhans cell. Immunohistochemically, Langerhans cells showed strong cytoplasmic staining with S-100 protein and CD1a. He was diagnosed Langerhans' cell histiocytosis involving the lung and liver.