국내 아메리칸 핏불테리어에서 발생한 열사병 증례 보고 = Heatstroke occurred in an American Pit Bull Terrier in Korea

다국어 초록 (Multilingual Abstract)

Heat stroke in a dog is a life-threatening syndrome characterized by a high body temperature over $41^{\circ}C$, by the central nervous system dysfunction, and by multiple organ dysfunction. A 11-month-old male American Pit Bull Terrier was presented to clarify the cause of death to diagnostic laboratory. This dog showed clinical signs such as high body temperature ($42^{\circ}C$), severe tachypnea, hematochezia, epistaxis and hemoptysis after transportation at hot summer time. At necropsy, there were hemorrhages in skin, serosa of stomach and small intestine, and also dark red fluid in lumen of intestine. Histopathologic examination revealed extensive hemorrhages in stomach, muscle, skin, and tongue. In microbiology, pathologic bacteria such as Pasteurella, Boedetella, Salmonella, Clostridium, and circulating virus in Korea such as CDV, CIV, CAV, CHV, CCV, CPIV were negative except CPV. There were many gross and microscopic lesions suggesting hest stroke while pathologic agents and related lesions were not detected. Therefore we diagnosed this case as heatstroke.

참고문헌 (Reference)

1 김규태, "급성 열사병으로 폐사한 아프리카 사자의 병리조직학적 소견" 한국임상수의학회 24 (24): 73-75, 2007

2 Radostits OT, "Veterinary Medicine: A textbook of the diseases of cattle, horses, sheep, pigs and goats" Saunders Ltd 47-48, 2007

3 Lin XJ, "Therapeutic effects of melatonin on heat-stroke-induced multiple organ dysfunction syndrome in rats" 50 : 436-444, 2011

4 Appel MJG, "Status report ; Canine viral enteritis" 173 : 1516-1518, 1978

5 Alzeer AH, "Serum enzymes and in heat stroke: prognostic implication" 43 : 1182-1187, 1997

6 Lu KC, "Role of circulating cytokines and chemokines in exertinal heatstroke" 32 : 399-403, 2004

7 Wang AY, "Renal failure and heatstroke" 17 : 171-179, 1995

8 Bruchim Y, "Pathological findings in dogs with fatal heatstroke" 140 : 97-104, 2009

9 Dematte JE, "Near-fatal heat stroke during the 1995 heat wave in Chicago" 129 : 173-181, 1998

10 Flournoy SW, "Heatstroke in dogs: pathophysiology and predisposing factors" 25 : 410-418, 2003

11 Holloway S, "Heatstroke in dogs" 14 : 1598-1604, 1992

12 Drobatz KJ, "Heat-induced illness in dogs:42 cases (1976-1993)" 209 : 1894-1899, 1996

13 Grogan H, "Heat stroke: implications for crit- ical care and anesthesia" 88 : 700-707, 2002

14 Leon LR, "Heat stroke: Role of the systemic inflammatory response" 109 : 1980-1988, 2010

15 Bruchim Y, "Heat stroke in dogs: a retrospective study of 54 cases (1999-2004) and analysis of risk factors for death" 20 : 38-46, 2006

16 Shapiro Y, "Experimental heat stroke, a model in dogs" 131 : 688-692, 1973

17 Bouchama A, "Evidence for endothelial cell activation/injury in heatstroke" 24 : 1173-1178, 1996

18 Finocchiaro R, "Effect of heat stress on production of Mediterranean dairy sheep" 88 : 1855-1864, 2005

19 Cecil RL, "Cecil textbook of medicine" Saunders Ltd 2358-2361, 1992

20 Macintire DK, "Canine parvovirus: II. Clinical signs, diagnosis and treatment" 19 : 291-302, 1997

21 Kathryn AD, "Alterations in hemostasis associated with hyperthermia in a canine model" 64 : 262-270, 2000