돌발성 난청의 지연성 호전에 관한 연구 = Clinical Analysis of Delayed Improvement in Sudden Sensorineural Hearing Loss

다국어 초록 (Multilingual Abstract)

Background and Objectives：The purpose of the study was to evaluate the time-dependent progress and the delayed improvement in patients who were already treated by combination therapy including oral steroid for idiopathic sudden sensorineural hearing loss. Subjects and Method：This study examined patients presenting with idiopathic sudden sensorineural hearing loss at a secondary referral and a university-based center over 10 years. This retrospective study included only those patients who could be followed up for at least 3 months. Results：Of 121 patients who recovered over the 3 months of follow-up period, 9.9% showed a delayed recovery of later than 1 month after discharge. Of 55 patients who did not recover until the discharge but recovered thereafter, 78.2% recovered within 1 month, 5.5% recovered between 1 to 2 months, 12.7% recovered between 2 to 3 months, and 3.6% recovered 3 months later after the discharge. The delayed recovery was found frequently in partial or slightly recovery groups by Siegels criteria. Conclusion：This study demonstrated the presence of delayed recovery in patients who were treated by combination therapy, including oral steroid for idiopathic sudden sensorineural hearing loss, although this result should be furtherstudied by additional research. (Korean J Otolaryngol 2006;49:695-8)

참고문헌 (Reference)

1 "Transtympanic steroids for treatment of sudden hearingloss" 125 : 142-146, 2001

2 "The treatment of idiopathic sudden sensorineural hearingloss" 8 : 467-73, 1975

3 "The efficacy of steroids in the treatmentof idiopathic sudden hearing loss.A double-blind clinical study" 106 : 772-6, 1980

4 "The effects of intratympanicsteroid injection for the patients with refractory sudden sensorineuralhearing loss" 48 : 706-712, 2005

5 "The effect ofintratympanic steroid injection for sudden sensorineural hearing loss" 45 : 1136-1140, 2002

6 "The comparisonof hearing recovery of sudden deafness treated with different protocols" 7 : 24-31, 2003

7 "Sudden deafness of obscure origin" 66 : 1237-67, 1956

8 "Sudden complete or partial loss of function of the octarussystemin apparently normal person" 32 : 407-29, 1944

9 "Prognosis and treatmentof sudden sensorineural hearing loss" 17 : 529-536, 1996

10 "Natural history of sudden sensorineuralhearing loss" 86 : 463-80, 1977

11 "Intratympanicsteroid injection for treatment of idiopathic sudden hearing loss" 133 : 251-259, 2005

12 "Intratympanic steroid perfusion for sudden sensorineuralhearing loss" 131 : 730-732, 2005

13 "Intratympanic steroid perfusion for refractorysudden sensorineural hearing loss" 132 : 527-531, 2005

14 "Intratympanic dexamethasone for profound idiopathicsudden sensorineural hearing loss" 132 : 902-905, 2005

15 "Intratympanic corticosteroids for sudden idiopathicsensorineural hearing loss" 26 : 878-881, 2005

16 "Effectiveness of intratympanicdexamethasone injection in sudden-deafness patients as salvagetreatment" 114 : 1184-1189, 2004

17 "Effectiveness of intratympanic dexamethasone injection insudden deafness patients as salvage treatment" 115 : 2005

18 "Clinical practice of sudden hearing loss" Jung myung dang Co 1995

19 "A clinical analysisof idiopathic sudden sensorineural hearing loss" 29 : 191-200, 1986