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RISS 인기검색어
- 검색키워드
- 주제어 : SULFA제 (검색결과 5 건)
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This is to study the molar Ratio, the precipitation Condition and the Color of Nickel Sulfa-drugs Complexes. I Can observe the Colors of the Complexes Whenever precipitation Condition is obtained With PH 8~9 The molar ratio of Complexes is determined by gravimetric method and Solvent extraction method. By Both methods as above we found the molar ratio of Sulfadrugs and Nikel of indentified Complexes 2:1
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Auther examined the absorption of sulfonamides influencing to the such antidiarrhoics as the bismuth-subnitrats of heavy metal salt, and as the tannic acid of organic astringency by the Wiseman's apparatus, through the small intestine of rat. The experiments carried out, two kinds of the concentration, the wateric buffor solution contained 0.5 mile - mole or 0.05 mili-mole of the each antidiarrhoics of the fixed administration of sulfonamides. The views of the determined are as followings; ① Generally, the absorptions of sulfonamides are augmentation by their antidiarrhoics which the bismuth subnitrate effected than the tannic acid, and N'-(2-thiazolyl) sulfanilamido have been influenced than the N'-(6-methoxy 3-pyridazinyl) sulfonamide. ② The velocity constants of absorbability are 6.43×10^(-4) per a minute of N'-(2-thiazolyl) sulfonilamide and 5.80×10^(-4) per a minute of N'-(6-methoxy 3-pyridazinyl ) sulfonamide versus the bismuth subnitrate combined with the 0.05 mili-mole concentration, the higher concentration of the antidiarrhoics have practically tended than that of lower concentrations on the absorption rates. ③ According to the estimated value, N'-(2-thiazolyl) sulfanilamide are inhibited than the N'-(6-methoxy 3-pyridazinyl) sulfonamide by the combined drugr are fact that N'-(2-thiazolyl) sulfanilamide bismuth salt on the chemical structure.
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Nitrofuran誘導體로써 抗菌劑合成에 關한 硏究 : 5-(2-nitro)pyromucic aldehyde와 sulfa劑의 縮合反應
For the purpose of synthesizing new antibacterial agents, the author designated the 5-nitropyromucic aldehyde possessig antimicrobial activity as an antibacterial body, and also designated that sulfanilamide derivatives possessing antibacterial activity are in the Auxo-antibacterial group. in order to synthesize New antibacterial agents, new five 5-nitropyromucic sulfanilamide derivatives are synthesized which are obtained by the action of the 5-nitropyromucic aldehyde as an antibacterial body on sulfonamide derivatives as an Auxo-antibacterial group, such as N'-acetylsulfanilamide, P-aminobenzen sulfonamide, N'-guanylsulfanilamide, N'-(4-methyl-2-thiazol) sulfanilamide, N'-(4-methyl-2- pyrimidinyl) sulfanilamide.
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