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함성호,고건일,김재백,손동환 圓光大學校 藥品硏究所 1995 藥品硏究所報 Vol.10 No.1
Drug delivery system by use of red cells was established to sustain the release of daunorubicin. Daunorubicin could be rapidly entrapped into red cellls by addition of distilled water containing daunorubicin and adenosine triphosphate(ATP). Daunorubicin could be entrapped into red cells within 2 minutes. This modified method induced no hemolysis and could sustain the level of intracellular ATP as same as normal red cells. Therefore, this method shows very efficient to make a red cell delivery system which has release pattern withour hemolytic leakage within a desire time since the hemolysis during the release would reflect the loss of intracellular ATP that might result on the decrease of the viability in vivo. Additionally this method would supply rapid and efficient for the dispensing because the short time and small volume are needed for the entrapping procedure.
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광소자용 미소렌즈 제작을 위한 GaAs/AlGaAs계 액상식각 및 에피택시
함성호,권영세 대한전자공학회 1997 電子工學會論文誌, D Vol.d34 No.9
A new etching technique of meltback was investigated for GaAs lensed optical devices with selective windows opending in the LPE (liquid phase epitaxy) system. In the meltback process, the etch depth and the etch shape were controlled by the degree of under-saturation, etch time and other parameters. A GaAs/AlGaAs DH layer was grown on the selectively etched hemispherical well for optical device application such as lensed surface emitting LED. The regrowth process were related with the coolin grate and the well to well spacing. A novel surface emitting LED with hemispherical AlGaAs lens was fabricated using the meltbakc and regrowth as the key process for AlaAs lens array. The light emitting efficiency of the LED was upto three times higher than the similar structure LED without lens. The meltback and regrowth technique was applicable to manufacture the optical device in LPE.
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