Preparation of core-shell type MBHA resin and its application to Solid-Phase Peptide Synthesis

최정현,이태경,이윤식 한국공업화학회 2007 한국공업화학회 연구논문 초록집 Vol.2007 No.-

미래 대한민국 해군력 역할과 발전

최정현,Choi, Joung-Hyun 한국해양전략연구소 2015 Strategy 21 Vol.18 No.2

This study is an attempt to look into the future role of the ROKN and to provide a strategic way forward with a special focus on naval strategic concept and force planning. To accomplish this goal, this research takes four sequential steps for analysis: 1) assessing the role and utility of naval power of ROKN since its foundation back in 1945; 2) forecasting features of various maritime threats to influence the security of Korea in the future directly or indirectly; 3) identifying the roles to be undertaken by future ROKN; and 4) recommending Korean way of naval force planning and the operational concept of naval power. This study seeks to show that ROKN needs comprehensive role to better serve the nation with respect to national security, national prosperity and development, and future battle-space management. To safeguard the national security of Korea, it suggests three roles: 1) national guard for the peaceful unification; 2) protector of the maritime sovereignty; and 3) suppressor to maritime threats. Three more roles are highlighted for national prosperity: 1) escort of the national economy; 2) guardian for national maritime activities; and 3) contributor to the world peace. These roles need to be closely connected with the role for the battle-space management. This paper addresses the need for a dramatic shift of the central operational domain from land to maritime in the future. This will eventually offer future ROKN a leading role for developing strategic concept and force planning rather than merely a supporting one. This study finally suggests 'balanced' strategy both in concept development and force planning. A balanced force planning is a 'must' rather than an 'option' when considering a division of function between Task Fleets and Area Fleets, constructing cutting-edge conventional forces such as Aegis destroyer, CVs, or submarines, and the mix of high-profile platform and low-profile when composing future fleets. A 'balance' is also needed in operational concept. The fleet should be prepared to fulfill its missions based on two different types of force operation i.e., coercive or cooperative application of the utility of naval force. The findings and recommendations of the study are relevant today, and will be increasingly important in the future to achieve various political goals required by enhancing the utility of naval power.

Reduction of Entrance Surface Dose Depending on Shielding Methods for Panoramagraphy

최정현,김성철,한동균 대한방사선과학회 2015 방사선기술과학 Vol.38 No.3

Panoramagraphy was the second most used intraoral radiography utilized in Korea, resulting in 17.8% in university dental hospitals, 24.8% in dental hospitals, and 31.4% in dental clinics. Depending on increased demand like orthodontics and implant, panoromagraphy tends to consistently increase.This study were used lead glasses and lead shielding to reduce unnecessary radiation to the eyeballs and thyroid. ESD was 41.4% when radiation was shielded with the lead glasses while reducing 47.3% of ESD by shielding the X-ray tube area with shielding lead. There was no statistically significant difference. The lead glasses is appropriated to reduce unnecessary radiation exposure to the eyeballs.

개원의 연수강좌 : 병원감염의 법적 측면

최정현 대한내과학회 2010 대한내과학회지 Vol.76 No.2S

麻黃辛芎散의 卽時型 알레르기 反應 抑制 效果에 關한 硏究

최정현,황충연,김남권,박민철,김진만,문상돈,Choe, Jeong-Hyeon,Hwang, Chung-Yeon,Kim, Nam-Gwon,Park, Min-Cheol,Kim, Jin-Man,Mun, Sang-Don 대한한방안이비인후피부과학회 2001 한방안이비인후피부과학회지 Vol.14 No.2

Mahwang-Shin-Gung-San has been found inhibiting the mast cell-mediated anaphylactic reaction. This report describes an inhibitory effect of Mahwang-Shin-Gung-San (MSGS) on the immediate-type cutaneous allergic reactions. MSGS has concentration -dependently inhibited the ear swelling response induced by compound 48/80 in mouse by intradermal injection. The mast cells in mouse ear tissue undergone ear-swelling response by compound 48/80 were stained by alcian blue/nuclear fast red. MSGS significantly inhibited the compound 48/80-induced degranulation from mast cells in ear tissue. MSGS concentration-dependently inhibited the histamine release from the rat peritoneal mast cells (RPMC) by compound 48/80. We also studied the effect of MSGS on mast cell-dependent passive cutaneous anaphylaxis (PCA) activated by dinitrophenyl IgE antibody. MSGS showed potent inhibition of PCA by oral administration. These results indicate that MSGS inhibits immediate-type allergic reactions by inhibition of mast cell degranulation in vivo and in vitro.

Русская земля, 어디에 있었으며, 무엇이었나?: 키예프 루시 시대 문헌과 개념을 중심으로

최정현 한양대학교 아태지역연구센터 2026 중소연구 Vol.49 No.4

Русская земля이라는 개념은 러시아와 우크라이나 그리고 벨라루시의 오늘날 동슬라브의 역사적 전신인 키예프 루시 시대 때부터 많은 해석과 논쟁을 낳는 개념이자 실체이다. 이른바 ‘루시 땅’(Русская земля)이라는 개념의 생성으로부터 시작해 중세 모스크바를 중심으로 한 중앙집권제 정치체의 형성 그리고 모스크바에서 상트페테르부르그라는 새로운 구심의 도입 등, ‘러시아 땅’ 내부에서도 상당한 이념적, 실제적 이동이 일어난 만큼, ‘루시 땅’이라는 추상적 관념에 대한 수용과 해석, 그리고 새로운 시각 역시 ‘러시아 땅’ 그 자체에 대한 생각만큼 복잡하고 입체적이다. 특히, 2022년부터 시작된 러시아와 우크라이나 간의 전쟁을 기화로, 더욱 ‘러시아 땅’에 대한 논의가 뜨거워지고 있는 상황에서, 그간 동슬라브 역사와 이념 지형에서의 ‘러시아 땅’에 대한 지리와 심상의 멘탈리티에 대해 논의를 시작하기 위한 첫 단계이자 가장 중요한 작업으로서, 동슬라브 역사의 시작이자 유일한 공통 역사인 키예프 루시 시대, 소위 ‘루시의 땅’(Русская земля)에 대해 문헌에서 확인되는 바와 그 역사적, 문화적, 상징적 개념에 대해 살펴보고자 한다. The concept of the “Russian Land” (Русская земля, Rus'kaia zemlia / Ruskaia zemlia) has long been a contested and multifaceted notion in East Slavic history, serving as both a historical entity and an ideological construct. It has generated extensive interpretations and debates from the era of Kievan Rus'—the shared historical origin of present-day Russia, Ukraine, and Belarus—through to contemporary times. This article examines the emergence and evolution of the “Rus' Land” as a concept, tracing its development from the medieval period onward. Beginning with its attestation in primary sources such as the Primary Chronicle, the notion of the Rus' Land initially denoted the territories associated with the Rurikid dynasty and the political-cultural space centered on Kyiv. Over time, however, its meaning underwent significant ideological and territorial shifts. These included the rise of centralized Muscovite political structures that claimed continuity with Kievan Rus', as well as the later relocation of the symbolic and administrative center to St. Petersburg under the imperial era. Such transformations highlight the fluidity of the “Russian Land” both as an abstract ideal and as a concrete geopolitical vision within East Slavic historical consciousness. Particularly since the outbreak of the Russia–Ukraine war in 2022, discourses surrounding the “Russian Land” have intensified, often invoked in competing national narratives and geopolitical claims. In this context, a critical first step toward understanding the mental maps, symbolic geographies, and ideological landscapes of East Slavic history is a close re-examination of the Kievan Rus' period—the sole commonly inherited historical foundation of the three East Slavic peoples. This study therefore focuses on the “Rus' Land” as documented in medieval sources, analyzing its historical, cultural, and symbolic dimensions. By elucidating the term's original meanings, semantic evolution, and instrumentalization across centuries, the article seeks to lay the groundwork for a more nuanced discussion of shared East Slavic heritage amid ongoing historiographical and political contestations.

스트링 B-트리를 이용한 게놈 서열 분석 시스템

최정현,조환규,Choe, Jeong-Hyeon,Jo, Hwan-Gyu 한국정보처리학회 2001 정보처리학회논문지 A Vol.8 No.4

As results of many genome projects, genomic sequences of many organisms are revealed. Various methods such as global alignment, local alignment are used to analyze the sequences of the organisms, and k -mer analysis is one of the methods for analyzing the genomic sequences. The k -mer analysis explores the frequencies of all k-mers or the symmetry of them where the k -mer is the sequenced base with the length of k. However, existing on-memory algorithms are not applicable to the k -mer analysis because a whole genomic sequence is usually a large text. Therefore, efficient data structures and algorithms are needed. String B-tree is a good data structure that supports external memory and fits into pattern matching. In this paper, we improve the string B-tree in order to efficiently apply the data structure to k -mer analysis, and the results of k -mer analysis for C. elegans and other 30 genomic sequences are shown. We present a visualization system which enables users to investigate the distribution and symmetry of the frequencies of all k -mers using CGR (Chaotic Game Representation). We also describe the method to find the signature which is the part of the sequence that is similar to the whole genomic sequence. 생명 과학의 발전과 많은 게놈(genome) 프로젝트의 결과로 여러 종의 게놈 서열이 밝혀지고 있다. 생물체의 서열을 분석하는 방법은 전역정렬(global alignment), 지역정렬(local alignment) 등 여러 가지 방법이 있는데, 그 중 하나가 k-mer 분석이다. k-mer는 유전자의 염기 서열내의 길이가 k인 연속된 염기 서열로서 k-mer 분석은 염기서열이 가진 k-mer들의 빈도 분포나 대칭성 등을 탐색하는 것이다. 그런데 게놈의 염기 서열은 대용량 텍스트이고 k가 클 때 기존의 온메모리 알고리즘으로는 처리가 불가능하므로 효율적인 자료구조와 알고리즘이 필요하다. 스트링 B-트리는 패턴 일치(pattern matching)에 적합하고 외부 메모리를 지원하는 좋은 자료구조이다. 본 논문에서는 스트링 B-트리(string B-tree)를 k-mer 분석에 효율적인 구조로 개선하여, C. elegans 외의 30개의 게놈 서열에 대해 분석한다. k-mer들의 빈도 분포와 대칭성을 보여주기 위해 CGR(Chaotic Game Representation)을 이용한 가시화 시스템을 제시한다. 게놈 서열과 매우 유사한 서열 상의 어떤 부분을 시그니쳐(signature)라 하고, 높은 유사도를 가지는 최소 길이의 시그니쳐를 찾는 알고리즘을 제시한다.

멀티모달 맥락정보 융합에 기초한다중 물체 목표 시각적 탐색 이동

최정현,김인철 한국정보처리학회 2023 정보처리학회 논문지(KTSDE) Vol.12 No.9

The Multi-Object Goal Visual Navigation(MultiOn) is a visual navigation task in which an agent must visit to multiple object goalsin an unknown indoor environment in a given order. Existing models for the MultiOn task suffer from the limitation that they cannotutilize an integrated view of multimodal context because use only a unimodal context map. To overcome this limitation, in this paper,we propose a novel deep neural network-based agent model for MultiOn task. The proposed model, MCFMO, uses a multimodal contextmap, containing visual appearance features, semantic features of environmental objects, and goal object features. Moreover, the proposedmodel effectively fuses these three heterogeneous features into a global multimodal context map by using a point-wise convolutionalneural network module. Lastly, the proposed model adopts an auxiliary task learning module to predict the observation status, goal directionand the goal distance, which can guide to learn the navigational policy efficiently. Conducting various quantitative and qualitativeexperiments using the Habitat-Matterport3D simulation environment and scene dataset, we demonstrate the superiority of the proposedmodel.

부정맥 신호의 조기진단을 위한 연속 심전도 모니터링 기기 개발

최정현,강민호,박준호,권기구,배태욱,박준모,Choi, Junghyeon,Kang, Minho,Park, Junho,Kwon, Keekoo,Bae, Taewuk,Park, Jun-Mo 한국융합신호처리학회 2021 융합신호처리학회 논문지 (JISPS) Vol.22 No.2

With the recent development of IT technology, research and interest in various bio-signal measuring devices are increasing. But studies related to ECG(electrocardiogram), which is one of the most representative bio-signals, particularly arrhythmic signal detection, are incomplete. Since arrhythmia has various causes and has a poor prognosis after onset, preventive treatment through early diagnosis is best. However, the 24-hour Holter electrocardiogram, a tool for diagnosing arrhythmia, has disadvantages in the limitation of use time, difficulty in analyzing motion artifact due to daily life, and the user's real-time alarm function in danger. In this study, an ECG and pulse monitoring device capable of continuous measurement for a long time, a real-time monitoring app, and software for analysis were developed, and the trend of the measured values was confirmed. In future studies, research on derivation of quantitative results of ECG signal measurement analysis is required, and further research on the development of an arrhythmic signal detection algorithm based on this is required.

움직임 벡터의 통계적 특성을 이용한 고속 움직임 추정

최정현,박대규,이경환,이법기,김덕규,Choi, Jung-Hyun,Park, Dae-Gyue,Lee, Kyeong-Hwan,Lee, Bub-Ki,Kim, Duk-Gyoo 대한전자공학회 2000 電子工學會論文誌-SP (Signal processing) Vol.37 No.2

고속 움직임 추정 방법들에서는, 움직임 추정 오차는 최적 탐색점에서 멀어질수록 단조 증가한다는 성질을 이용하여, 계산량을 줄인다 본 논문에서는 먼저, 참조 탐색점들의 MAE (mean absolute error) 차가 클 때에, 대부분의 움직임 벡터는 작은 MAE의 참조 탐색점 방향에서 나타난다는 통계적 특성을 조사하였다 그러므로, 이 특성을 이용하여 탐색점 수를 줄일 수 있는 고속 움직임 추정 방법을 제안한다 모의 실험 결과, 기존의 고속 움직임 추정 방법들에 비해서는 비슷한 성능을 유지하면서 계산량을 줄일 수 있었다. In Fast motion estimaion algorithms, they reduce the computational complexity using the assumption that the matching error increases monotonically as the search moves away from the global minimum error In this paper, we first investigate the statistical characteristics of motion vector that the motion vector mostly occures on the side of small MAE (mean absolute error) between the reference search points when the MAE difference of them is large Therefore, we propose a fast motion estimation algorithm using this property and can reduce the number of search points The computer simulation result shows that the proposed method reduces computational complexity compared with conventional fast algorithms.