[경제보도 부문 제115회 이달의 방송기자상] 천국과 지옥을 오간 개미투자자들…‘의문의 30분’

이기주 (사)방송기자연합회 2018 방송기자 Vol.43 No.-

[취재보도 부문_제166회 이달의 방송기자상] 말로만 떠돌던 ‘사적 수행’을 확인하다 : 〈‘1호기 속 수상한 민간인’ 사적 보좌 사적 채용 의혹 연속보도〉2022년 7월 5일~8일 보도 MBC 이기주, 이정은, 신수아 기자

이기주 (사)방송기자연합회 2022 방송기자 Vol.68 No.-

기계적 자극이 치주인대 세포의 osteoprotegerin과 receptor activator of nuclear factor κB ligand mRNA 발현에 미치는 영향

이기주,이승일,황충주,,옥승호,전옥순 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.4

본 연구는 치주인대 세포에 지속적이고 점진적 인장력을 가하여 치아 이동 시 형성되는 인장부위의 기계적 자극에 대한 생화학적 전달과 치조골 흡수와 생성 조절 기전을 이해하고자 하였다. 치주인대 세포가 배양된 유연한 성장 표면을 가진 배지에 지속적이고 점진적인 인장력을 가하고 골흡수 인자인 PGE_(2)와 골형성 인자인 ALP의 생성량을 1, 3, 6, 12시간 후에 측정하여 정량비교하였고 파골세포 분화기전을 조절하는 OPG, RANKL의 인자들과 matrix metalloproteinase (MMP)-1, -8, -9, -13, tissue inhlbitor of matrix metalloproteinase (TIMP)-1의 인자들을 역전사 중합효소 연쇄반응 검사하여 m-RNA 발현을 비교한 결과, 치주인대 세포에 인장력을 가한 경우 대조군보다 PGE_(2)의 농도가 적었고 (p<0.05) ALP의 농도 변화는 없었으며 OPG의 mRNA 발현이 증가하였으나, RANKL의 mRNA 발현은 감소하였다. 그리고 TIMP-1과 MMP-1, -8, -9, -13의 mRNA 발현이 대조군과 차이가 없었다. 이상의 연구에서 사람의 치주인대 세포는 점진적이고 지속적인 인장력에 대한 반응으로 PGE_(2)의 생성과 RANKL의 mRNA 발현은 감소하고 OPG의 mRNA 발현은 증가하여 골흡수를 억제하는 효과를 보이는 것으로 나타났다. Tooth movement is a result of mutual physiologic responses between the periodontal ligament and alveolar bone stimulated by mechanical strain. The PDL cell and osteoblast are known to have an influence on bone formation by controlling collagen synthesis and alkaline phosphatase activation. Moreover, recent studies have shown that the PDL cell and osteoblast release osteoprotegerin(OPG) and the receptor activator of nuclear factor κB ligand (RANKL) to control the level of osteoclast differentiation and activation which in turn influences bone resorption. In this study, progressively increased, continuous tenslonal force was applied to PDL cells. The objective was to progressively increased. continuous tensional force was applied to PDL cells. The objective was to find out which kind of biochemical reactions occur after tensional force application and to illuminate the alveolar bone resorption and apposition mechanism. Continuous and progressively increased tensile force was applied to PDL cells cultured on a petriperm dish wlth a flexible membrane. The amount of PGE_(2) and ALP synthesis were measured after 1, 3, 6 and 12 hours of force application. Secondly, RT-PCR analysis was carried out for OPG and RANKL whlch control osteoclast differentiation and MMP-1, -8, -9, -13 and TIMP-1 which regulate the resolution of collagen and resorption of the osteoid layer. According to the results, we concluded that progressively increased, continuous force application to human PDL cells reduces PGE_(2) synthesls, and increases OPG mRNA expression.

정신분열병 증상을 동반한 결절성경화증 1례

이기주,오세중,이정호 인제대학교 1990 仁濟醫學 Vol.11 No.4

The authors experienced a case of tuberous sclerosis accompanied with schizophrenic symptoms in 14 year-old female patient. This case showed the typical symptoms of tuberous sclerosis, which were adenoma sebaseum, mental retardation, seizure, ungual fibroma, hypopigmented spots, phacoma in eye, angiofibroma in kidney and periventricular calcifications. In addition to above symptoms, schizophrenic-like manifestations, ie ; were also noted in this case. We reported this case and reviewed the relevant literatures on tuberous sclerosis and tuberous sclerosis with psychotic manifestations.

職業公務員 制度

李基柱 건국대학교 1974 法經論叢 Vol.1974 No.9

필터 버블 완화를 위한 다면적 추천 시스템

이기주,이승건,김남규 한국지능정보시스템학회 2026 지능정보연구 Vol.32 No.1

기존 추천 시스템은 사용자가 과거에 선호한 아이템과 유사한 상품만을 반복적으로 추천하는 필터 버블(Filter Bubble) 문제를 야기한다. 이는 기존 추천 시스템의 성능 평가가 지나치게 정확도 중심으로 이루어졌기 때문이며, 정확도와 다양 성 간의 상충 관계로 인해 필터 버블 현상은 추천 시스템 연구 분야의 난제로 인식되어 왔다. 이에 본 연구에서는 아이템 추천 모델과 카테고리 추천 모델을 통합하여 다양한 후보를 선정하고, 두 가지 임베딩 정보를 활용하여 거대 언어 모델 (Large Language Model, LLM) 기반 재 순위화를 수행하는 다면적 임베딩 통합 방법론(Multi-Faceted Embedding Integration)을 제안한다. 제안 방법론은 카테고리 선호도에 따라 후보군을 균형있게 구성한 후, 아이템 임베딩과 카테고리 임베딩을 프로젝터를 통해 변환하여 LLM 프롬프트에 주입하고 버벌라이저로 최종 순위를 도출한다. Amazon Toys & Games 데이터셋을 활용한 실험 결과 제안 방법론은 N-다양성 데이터셋에서 Recall@10 기준 LlamaRec 대비 45%, LRURec 대비 56%의 성능 향상을 보였으며, 전체 데이터셋에 대해서도 필터 버블을 고려한 기존 추천 모델보다 높은 정 확도를 나타냈다. 결론적으로 본 연구에서 제안한 다면적 추천 시스템은 높은 수준의 정확도를 유지하면서도 아이템 추천 의 다양성을 확보함을 확인하였으며, 이를 통해 전자상거래 플랫폼의 사용자 경험 개선과 상품 다양성 확보에 기여할 수 있을 것으로 기대된다. Traditional recommender systems often suffer from the filter bubble problem, repeatedly suggesting items similar to those users have preferred in the past. This issue arises largely because existing systems have been evaluated predominantly through accuracy-oriented metrics, and the inherent trade-off between accuracy and diversity has made filter bubbles a long-standing challenge in recommender systems research. To address this, we propose a Multi-Faceted Embedding Integration method that integrates an item recommendation model with a category recommendation model to generate diverse candidate items, and performs large language model (LLM)-based re-ranking using two types of embedding information. The proposed method constructs a balanced candidate pool according to category-level preferences, transforms item and category embeddings through projectors, and injects them into an LLM prompt, where a verbalizer produces the final ranking. Experiments conducted on the Amazon Toys & Games dataset show that our method improves Recall@10 by 45% compared to LlamaRec and by 56% compared to LRURec on the N-diversity dataset. It also outperforms existing filter-bubble-aware recommendation models in overall accuracy on the full dataset. In conclusion, the proposed multi-faceted recommendation framework maintains high accuracy while enhancing item diversity, thereby contributing to improved user experience and greater product variety in e-commerce platforms.

권두언-창조경제시대, 어떻게 준비할 것인가?

이기주 한국공학교육학회 2013 Ingenium(人材니움) Vol.20 No.2

창조경제가시대의화두로회자되고있다. 국내에서는박근혜정부의정책패러다임으로 제시되어 더욱 관심이 증가하고 있다. 일찍이 1994년 호주에서 발간된 “Creative Nation” 보고서를 시작으로 영국의 문화미디어 스포츠부(DCMS)가 “개인의 창조성과 스킬, 재능 등에 기반한 산업 내지지적재산권의 창출과 이용을 통해 부와 일자리를 만들어낼 수 있는 잠재력을 지닌 산업”, 즉 창조산업의 육성의 필요성을 제기하면서 본격화 되었다. 이후, 창조경제는 영국의 호킨스에 의해 2001년 이론적으로 발전되었고 여러 학자들에 의해 더욱 정교화 되는 과정을 거쳤다.

Thermoelectric Properties of n-type Bi₂Te2.7Se0.3 Compounds Prepared by Spark Plasma Sintering

이기주,Jing-Wen Xu,임철호,조원승 대한금속·재료학회 2008 METALS AND MATERIALS International Vol.14 No.4

In this study, the thermoelectric properties of 0.1 wt.% CdI₂-doped n-type Bi₂Te2.7Sb0.3 compounds, fabricated by SPS in a temperature range of 250℃ to 350℃, were characterized. The density of the compounds was increased to approximately 100 % of the theoretical density by carrying out consolidation at 350℃. The Seebeck coefficient, thermal conductivity, and electrical resistivity were dependent on a hydrogen reduction process and the sintering temperature. The Seebeck coefficient and the electrical resistivity increased with the reduction process. Also, electrical resistivity decreased and thermal conductivity increased with sintering temperature. The results suggest that carrier density and mobility vary according to the reduction process and sintering temperature. The highest figure of merit, 1.93 × 10-³K-¹ , was obtained for the compound consolidated at 350℃ for 2 min. In this study, the thermoelectric properties of 0.1 wt.% CdI₂-doped n-type Bi₂Te2.7Sb0.3 compounds, fabricated by SPS in a temperature range of 250℃ to 350℃, were characterized. The density of the compounds was increased to approximately 100 % of the theoretical density by carrying out consolidation at 350℃. The Seebeck coefficient, thermal conductivity, and electrical resistivity were dependent on a hydrogen reduction process and the sintering temperature. The Seebeck coefficient and the electrical resistivity increased with the reduction process. Also, electrical resistivity decreased and thermal conductivity increased with sintering temperature. The results suggest that carrier density and mobility vary according to the reduction process and sintering temperature. The highest figure of merit, 1.93 × 10-³K-¹ , was obtained for the compound consolidated at 350℃ for 2 min.

45,XI 46,XXr 핵형의 터너 증후군 1례

이기주,이봉규,정중화,이만재,전용준,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2

A 16-years-old-girl was presented with chief complaints of dizziness and exertional dyspnea. She was tall 146 cm (less than the fifth percentile) and sexually developed normally. But she experienced intermittent menorrhagia. She had a shield chest, a low-set nuchal hairline and a short left metatarsal bone. There were no other dysmorphic facial features, no webbed neck, no cubitus valgus, & no mental retardation. The blood hemoglobin was 6.2 g/dl and peripheral blood smear showed hypochromic microcytic red blood cells. Bone marrow showed moderate erythroid hyperplasia and normoblast with scant cytoplasm, and it was not stained by Prussian Blue stain. She had a mosaicism of 45.X/46.XXr in the cells, cultured from the peripheral blood. Fifty five cells were examined. Forty-two cells had 45 chromosome, with one X. The remaining thirteen cells had 46 chromosomes per cell, with a normal X and a ring X chromosome. The mother was 155 cm tall and had normal karyotype. We herein report a Turner syndrome patient with a ring X chromosome with a brief review of literature.

十二味寬中湯, 凉膈散火湯, 荊防瀉白散이 백서의 혈압 및 국소뇌혈류량에 미치는 영향

李基珠,金敬堯 한국전통의학연구소 1999 한국전통의학지 Vol.9 No.2

1. Background and Purpose For many years, Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan have been used as a therapeutic agent in constitutional disease. The effects of three prescriptions on the vascular system is not well-known. The purpose of this study is to determine the effects of these prescriptions on blood pressure(BP) and regional cerebral blood flow(rCBF). 2. Methods I injected a vein of rat with extracts of Sibimikwanjungtang, Yangkyeoksanhwatang and Hyeongbangsabaeksan with five kinds of dose and measured BP and rCBF. 3. Results After injected Sibimikwanjungtang, BP was not changed but rCBF was increased in a dose-dependent manner. After injected Yangkyeoksanhwatang, BP was elevated and rCBF was increased in a dose-dependent manner. After injected Hyeongbangsabaeksan, BP was not changed but rCBF was increased in a dose-dependent manner.