A Power and Performance Management Simulation Platform for Web Application Server Cluster

Zhi Xiong,Zhongliang Xue,Weihong Cai,Lingru Cai,Juan Yang 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.12

Web application server cluster has been widely used to improve the performance of web application servers. Because web load is highly variable, we need to dynamically manage cluster’s deployment so as to reduce power consumption and meanwhile satisfy load performance demand. To facilitate researchers to evaluate a management strategy or choose key parameters for it, we propose a CloudSim-based simulation platform in this paper. It can simulate different cluster deployment algorithm, request scheduling algorithm and load feature, where cluster’s deployment includes the on/off state, CPU frequency and request scheduling parameter(s) of each server. By the aid of HookTimer component, the platform supports periodical and conditional deployment trigger modes, and can calculate some common performance indicators. The usage of interface, dynamic proxy technique and XML configuration file make the platform have good extensibility and configurability. In addition, a request-number-triggered management strategy is proposed and simulated by the platform. The simulation results demonstrate the feasibility of the platform.

Heat transfer due to pulsating flow through a pipe partially filled with porous media

Zhixiong GUO,성형진 대한기계학회 1996 대한기계학회 춘추학술대회 Vol.- No.-

Attention-based for Multiscale Fusion Underwater Image Enhancement

Zhixiong Huang,Jinjiang Li,Zhen Hua 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.2

Underwater images often suffer from color distortion, blurring and low contrast, which is caused by the propagation of light in the underwater environment being affected by the two processes: absorption and scattering. To cope with the poor quality of underwater images, this paper proposes a multiscale fusion underwater image enhancement method based on channel attention mechanism and local binary pattern (LBP). The network consists of three modules: feature aggregation, image reconstruction and LBP enhancement. The feature aggregation module aggregates feature information at different scales of the image, and the image reconstruction module restores the output features to high-quality underwater images. The network also introduces channel attention mechanism to make the network pay more attention to the channels containing important information. The detail information is protected by real-time superposition with feature information. Experimental results demonstrate that the method in this paper produces results with correct colors and complete details, and outperforms existing methods in quantitative metrics.

MiR-506 Promotes Natural Killer Cell Cytotoxicity against Human Hepatocellular Carcinoma Cells by Targeting STAT3

Zhixiong Su,Xinping Ye,Liming Shang 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.1

Purpose: It is well documented that natural killer (NK) cytotoxicity against hepatocellular carcinoma (HCC) cells is impaired inHCC, which might account for the failure of anti-tumor immune response. miRNAs are considered as important regulators forthe development and functions of NK cells. However, the entire role of miR-506 in NK cells remains far from being addressed. Materials and Methods: The expressions of miR-506 and signal transducer and activator of transcription 3 (STAT3) mRNA in primaryNK cells from HCC patients and healthy controls were detected by quantitative real-time PCR. NK cell cytotoxicity was assessedby CFSE/7AAD cytotoxicity assay and lactate dehydrogenase assay. Luciferase reporter assay, RNA immunoprecipitationassay, and western blot were conducted to confirm the interaction between miR-506 and STAT3. Results: miR-506 expression was downregulated and STAT3 mRNA was upregulated in primary NK cells from HCC patients. PrimaryNK cells from HCC patients showed remarkably reduced cytotoxicity against SMMC7721 or HepG2 cells. NK cell cytotoxicitywas positively correlated with miR-506 expression and negatively correlated with STAT3 mRNA expression. Additionally, miR-506 overexpression enhanced NK cell cytotoxicity against HCC cells, while miR-506 inhibitor showed the reverse effect. Moreover,miR-506 could suppress STAT3 expression by directly targeting 3'-untranslated regions of STAT3. A negative correlation betweenmiR-506 and STAT3 mRNA expression in HCC patients was observed. Mechanistically, overexpressing STAT3 greatly reversedmiR-506-mediated promotion of NK cell cytotoxicity against HCC cells. Conclusion: miR-506 enhanced NK cell cytotoxicity against HCC cells by targeting STAT3, suggesting that modulating miR-506expression maybe a promising approach for enhancing NK cell-based antitumor therapies.

Macrokinetic Model for Gluconobacter oxydans in 2-keto-L-gulonic Acid Mixed Culture

Zhixiong Zhang,Xinjie Zhu,Ping Xie,Junwei Sun,Jingqi Yuan 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.5

A set of kinetic models have been developed for the production of 2-keto-L-gulonic acid from L-sorbose by a mixed culture of Gluconobacter oxydans and Bacillus megaterium. A metabolic pathway is proposed for Gluconobacter oxydans, and a macrokinetic model has been developed for Gluconobacter oxydans, where the balances of some key metabolites, ATP and NADH are taken into account. An unstructured model is proposed for concomitant bacterium Bacillus megaterium. In the macrokinetic model and unstructured model, the mechanism of interaction between Gluconobacter oxydans and Bacillus megaterium is investigated and modeled. The specific substrate uptake rate and the specific growth rate obtained from the macrokinetic model are then coupled into a bioreactor model such that the relationship between the substrate feeding rate and the main state variables, such as the medium volume, the biomass concentrations, the substrate,and the is set up. A closed loop regulator model is introduced to approximate the induction of enzyme pool during lag phase after inoculation. Experimental results demonstrate that the model is able to describe 2-keto-Lgulonic acid fermentation process with reasonable accuracy.

Intelligent fault diagnosis method for marine diesel engines using instantaneous angular speed

Zhixiong Li 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.8

The normal operation of marine diesel engines ensures the scheduled completion and efficiency of a trip. Any failures may result in significant economic losses and severe accidents. It is therefore crucial to monitor the engine conditions in a reliable and timely manner in order to prevent the malfunctions of the plants. This work describes and evaluates the development and application of an intelligent diagnostic technique based on the integration of the empirical mode decomposition (EMD), kernel independent component analysis (KICA), Wigner bispectrum and support vector machine (SVM). It is an extension of the previous work on the fault detection for a diesel engine using the instantaneous angular speed (IAS). In this study, in order to solve the underdetermined blind source separation (BSS)problem the combination of EMD and KICA is firstly presented to estimate IAS signals from a single-channel IAS sensor. The KICA is also applied to select distinguished features extracted by Wigner bispectrum. The SVM is then employed for the multi-class recognition of the marine diesel engine faults in an intelligent way. Numerical simulations using a 6-cylinder engine model and real IAS data measured on the ship named “Hangjun 20” are used to evaluate the proposed method. Both the numerical and experimental diagnostic results have shown high efficiency of the proposed diagnostic method. Distinct fault features of the IAS signals have been extracted by the EMD-KICA and Wigner bispectrum, and the fault detection rate of the SVM is beyond 94.0%. Thus, the proposed method is feasible and available for the fault diagnosis of marine diesel engines.

Modeling of Left Ventricular Motion and Hemodynamic Analysis Based on CT Tomography

Zhixiong Li,Liang Qi,Wei Han,Minzu Zhang,Tianci Duan,Yan Qiang 한국유체기계학회 2024 International journal of fluid machinery and syste Vol.17 No.1

Based on Computed Tomography (CT) tomography images of the human heart, a 3D reconstruction and wall optimization of the heart was performed by using Mimics to model the motion of the left ventricular overflow wall. The non-Newtonian blood flow in the left ventricle was numerically simulated using the dynamic mesh technique based on User Defined Functions (UDF) programming of the left ventricular wall motion. When the left ventricle is diastolic, the internal pressure gradually increases, the blood flow structure approximates the physiological blood flow pattern, the rate at the mitral orifice first increases and then decreases, and a local high stress zone appears. When the left ventricle is systolic, the pressure gradient is significant, the internal pressure decreases and the rate at the aortic valve orifice shows a pattern of increasing and then decreasing. The dynamic simulation of left ventricular blood flow provides a feasible technical solution for the fluid dynamics analysis of cardiac physiological and pathological processes

Antioxidant, Antibacterial, Tyrosinase Inhibitory, and Biofilm Inhibitory Activities of Fermented Rice Bran Broth with Effective Microorganisms

Li, Zhixiong,Lee, Jin-Tae,Cho, Moo-Hwan 한국생물공학회 2010 Biotechnology and Bioprocess Engineering Vol.15 No.1

The effective microorganism fermentation extract (EM-X) is a refreshment beverage widely consumed in East Asia. Due to the antioxidant property of the health beverage, EM-X has potential benefits for the human immune system and has been generally accepted in clinical practice. In search of new functions of EM-X, another version of EM-X, named EM-YU in this study, which is fermented from rice bran, seaweed, and kiwifruit with effective microorganisms demonstrates high antioxidant, antibacterial, tyrosinase inhibition activities, and biofilm inhibition activity of pathogenic bacteria. The antioxidant activity of 1.8% EM-YU was equivalent to that of 0.01 mg/mL vitamin C. Also, EM-YU clearly inhibited the cell growth of two pathogenic bacteria, Escherichia coli O157:H7 and Pseudomonas aeruginosa PAO1; and EM-YU broth (6.7%) inhibited (55${\pm}$1%) the activity of mushroom tyrosinase. Moreover, the ethyl acetate extract of EM-YU, called EM-YU-EX (0.6 mg/mL), 7-fold reduced the biofilm formation of E. coli O157:H7 without affecting its cell growth. It is the first report that EM-X variant possess antibacterial, tyrosinase inhibitory, and biofilm inhibitory activities. These results support other beneficial properties of the natural health product EM-X variant (EM-YU).

Evaluation of Pedestrians Potential Risk at Non-Signalized Intersections Based on Predicted Relative Time-To-Collision Using Deep Learning Trajectory Prediction Method

Tengfeng Lin,Zhixiong Jin,Seongjin Choi,Hwasoo Yeo 대한교통학회 2023 대한교통학회 학술대회지 Vol.89 No.-

Evaluation of Pedestrians Potential Risk at non-Signalized Intersections Based on Predicted Relative Time-Collision Using Deep Learning Trajectory Prediction Method

Tengfeng Lin,Zhixiong Jin,Seongjin Choi,Hwasoo Yeo 대한교통학회 2023 대한교통학회 학술대회지 Vol.89 No.-