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      • KCI등재

        고등학생들의 시험불안과 대처전략

        이미숙,이형영,최영 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

        Objects : The purpose of this study was to see the relationship between the level of test anxiety and coping strategy in high school students. Methods : The subjects were 952 high school students(411 boys and 541 girls) in Kwangju. A self reporting questionnaire, test anxiety scales and coping strategy scales were handed out to the students on April 1994. Result : 1) Test anxiety scores in gradeⅠ and Ⅱ were higher than those in grade Ⅲ. Test anxiety scores were correlated with difficulty in attention, depressive mood and suicidal ideas. 2) The high test anxiety group used more coping strategies than the low test anxiety group and coping strategies were varied among high test anxiety groups according to the grade. 3) Test anxiety correlated positively with coping strategy. 4) Predicting factors of test anxiety were grade, attention difficulty, depressive mood, suicidal idea, withdrawal or disengagement, life evert, internal suppression of emotion and distance. Conclusion : The above results suggest that test anxiety correlated positively with coping strategy and the high test anxiety group used much more coping strategies in order to overcome stress using their potential inner resource than the low test anxiety group.

      • 중년여성의 운동 예측모형

        이미라,소희영 충남대학교 간호과학연구소 2002 충남대 간호학술지 Vol.5 No.1

        This study was conducted to test the hypothetical model designed to explain exercise behavior of middle-aged women. This hypothetical model was based on behavior-related theories and exercise-related literature. Exogenous variables were exercise habit and perceived subjective norm. Endogenous variables were exercise benefit, exercise barrier, exercise-related affect, exercise self-efficacy, exercise intention, and exercise. A convenience sample of 152 middle-aged women was studied. SAS PC Program and LISREL 8.12a program were used for descriptive statistics and linear structural relationship(LISREL) modeling. The results were as follows. 1)The overall fit of the hypothetical model was acceptable(χ2 34.86(p=0.0015), χ2/df 2.49, RMSEA 0.09, standardized RMR 0.05, GFI 0.95, AGFI 0.85, NFI 0.92, NNFI 0.87, CFI 0.95). 2)The results of statistical testing of hypotheses were as follows. (1)The varibles in this hypothetical model explained 95% of the variance of the exercise behavior. (2)Habit was the most important variable to explain exercise behavior, followed by self-efficacy, barrier, affect and benefit. Subjective norm and intention were not significant predictors of exercise behavior. Habit and self-efficacy had a significant direct effect on exercise behavior. Barrier and intention did not directly influence on exercise behavior. Habit, benefit, barrier and affect had a significant indirect effect on exercise behavior through other variables in this hypothetical model. Norm had no indirect effect on exercise behavior. (3)The direct path between habit and benefit, habit and barrier, habit and self-efficacy, norm and barrier, benefit and affect, barrier and self-efficacy, and affect and self-efficacy were significant. The indirect path between habit and affect, habit and self-efficacy, benefit and self-efficacy, benefit and intention were significant. In conclusion, this study verified that the hypothetical model constructed in this study could be used effectively as a reference for further structural modeling or interventional studies.

      • 국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

        이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

        Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

      • Rat의 DNA Polymerase β cDNA가 도입된 Transgenic Drosophila의 체세포 돌연변이 유발에 관한 연구

        최영현,유미애,이원호 부산대학교 유전공학연구소 1995 분자생물학 연구보 Vol.11 No.-

        The effects of DNA polymerase β on the somatic chromosome mutations and mitotic recombinations were investigated using the transgenic Drosophila bearing chimeric gene consisting of a promoter region of Drosophila actin 5C gene and rat DNA polymerase β. For detecting the somatic chromosome mutations and mitotic recombinations, the heterozygous (mwh/+) strains possessing or lacking transgene pel β were used. The spontaneous frequency of small mwh spots, due deletion or nondisjunction etc, in the non-transgenic w strain and the transgenic p[pol β]-130 strain was 0.351 and 0.606, respectively. The spontaneous frequency (0.063) of large mwh spots, arises mostly from somatic recombination between the centromere and the locus mwh, in the transgenic p[pol β]-130 strain was about three times higher than that (0.021) of the non-transgenic w strain. The mutant clone frequencies of small and large mwh spots induced by N-methyl-N'-nitro-N-nitrosoguanidine and ethyl methanesulfonate in the transformant p[pol β]-130 were higher than those in the host strain w. The present results suggest that rat DNA polymerase β participate at least in the somatic chromosome mutations and mitotic recombination processes.

      • KCI등재

        정신분열증 환자에서 청각 인식유발전위와 임상적 호전의 연관성에 대한 예비연구

        박미경,최영,이형영 대한신경정신의학회 1999 신경정신의학 Vol.38 No.1

        연구목적 : 본 연구는 정신분열증 환자에게 치료에 대한 반응을 예측할 수 있는 객관적 지표를 알아보려는 노력으로 시행되었다. 방 법 : 연구대상은 정신과 진단편람 제 4권 (Diagnostic and Statistical Manual of Mental Disorders-Ⅳ)의 정신분열증 진단기준을 만족시키는 23명의 입원환자였다. 치료 전 또는 치료 초기에 청각 인식유발전위를 시행하였으며 임상증상의 변화는 치료 전과 치료 4주 후 양성 및 음성 증후군 척도(Positive and Negative Syndrome Scale)를 통하여 측정하였다. 결 과 : 1) 양성척도의 호전정도는 P1과 N1의 잠복기와 유의한 정 상관관계를 보이고, P3 잠복기, P2의 전위와는 유의한 역 상관관계에 있었다. 2) 음성척도의 호전정도는 P3 잠복기와 유의한 역 상관 관계를 보였다. 3) 일반정신병리척도의 호전도 또한 P3 잠복기와 유의한 역 상관관계를 보였다. 결 론 : 이러한 결과는 치료전 실시한 청각 인식유발인자가 정신분열증 환자에게 임상적 호전의 예측인자로서 가치가 있음을 시사한다. 향후 많은 환자를 대상으로 지속적인 연구가 필요하다. Objectives : The purpose of this study was to see the correlation between the auditory cognitive evoked potential and the clinical improvement in schizophrenics. Method : The subjects were 23 patients with schizophrenia. Auditory cognitive evoked potential was examined at pretreatment or acute phase of treatment. The change of symptom was assessed by the PANSS(Positive and Negative Syndrome Scale) before drug treatment and in the 4th week of treatment. Results : 1) The change of positive subsclae was positively correlated with P1 latency(p〈.05), N1 latency(p〈.05) and negatively correlated with P3 latency(p〈.05), P2 amplitude(p〈.05). 2) The change of negative subscale was negatively correlated with P3 Latency(p〈.05). 3) The change of general psychopathology subscale was negatively correlated with P3 latency(p〈.05). Conclusion : These results suggest that the auditory cognitive evoked potential in schizophrenic patients could be valuable on prediction of clinical improvement. But, further studies are required to support these results.

      • 케일 쥬스에 의한 AFLATOXIN B_1의 유전독성 억제 효과

        최영현,박건영,이선미,유미애,이원호 부산대학교 유전공학연구소 1995 분자생물학 연구보 Vol.11 No.-

        The inhibitory effect of the fresh juice of kale on the genotoxicity induced by aflatoxin B_1 (AFB_1) in Salmonella and Drosophila was investigated. The kale juice had strong inhibitory activity for His^- to His^+ reverse-mutations induced by AFB_1 acting on S. typhimurium TA100. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. Using the wing hairs spot test, we found that the formation of mutant hairs in adult flies as a result of feeding with AFB_1 in their larval stages was efficiently inhibited by coadministration of the fresh juice of kale, which revealed that it can inhibit gene mutation, deletion and mitotic chromosomal recombination. These results seem to suggest that kale juice may exert its inhibitory effect to mutagenic and/or carcinogenic properties of DNA damaging agents.

      • 한국에서 통용되고 있는 지폐에서의 미생물 오염 분석

        장효원,이미영,오계헌 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.2

        The purpose of this work was to investigate the microbiological distribution and contamination from korean currency that is circulated generally among various kinds of people. Fifty 1,000-won bills were collected by seasons and regions for 18 months. supernatants derived from bills treated by ultrasonicator with .0.8% saline were inoculated and incubated on various selective media such as mannitol salt agar, potato dextrose agar, plate count agar, bismuth sulfite glucose glycine yeast extract agar, luria-Bertani agar. As the results, various kinds of bacteria and fungi including Staphylococcus aureus, Staphyolcoccus epidermidis, Streptococcus mitis, Streptococcus salivarius, Escherichia coli, Enterobacter sp., Salmonella sp., Pseudomonas sp., Candidasp. from 1,000-won bills grew on the solid media. Bacterial contamination was higher in spring and summer compared to winter, whereas fungal contaminatioj was predominated in winter. Especially, 1,000-won bills collected in fish markets and korean traditional markets were heavily contaminated by E. coli, staphylococcus aureus, Pseudomonas sp. Streptococcus sp.,Salmonella sp., and -hemolytic Bacillus. Similar results were obtained from 5,000-won bills and 10,000-won bills as well. In consequence, it was proven that korean currency of bank notes in current use was significantly contaminated by many pathogenic microorganisms.

      • 수중액중의 중금속에 대한 녹차의 흡착성질

        권이열,김미경,이동섭,홍순영,전혜옥 漢陽大學校 環境科學硏究所 1992 環境科學論文集 Vol.13 No.-

        본 연구는 수용액중의 중금속에 대하여 녹차를 이용하여 흡착능을 고찰하였다. 실험에 사용된 녹차는 시판되는 "태평양화학 설록차(2번차)"를 40∼60mesh로 만들어 사용하였다. 각 중금속이온을 함유한 시료용액에 녹차를 첨가하여 흔든 다음, 원심분리해서 상등액중의 각 이온농도를 원자흡광광도계로 측정했다. 그 결과, 각 조건에서 녹차에 의한 중금속의 최대흡착율은 Cu(Ⅱ)는 65∼78%, Cd(Ⅱ)는 78∼82%, Pb(Ⅱ)는 82∼92%였으며, 반응초기 10분간에 최대흡착율의 90%가 일어났다. The adsorptivities of the green-tea particles on Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) ions were examined by measurements of the adsorption percentage under various conditions, and the method to collect and remove the metallic ion in aqueous solutions were described. Each of 100ml sample solution of Pb(Ⅱ),Cd(Ⅱ) and Cu(Ⅱ) ions mixed with 2g of the green-tea under stirring for minutes. The solutions were then centrifuged, and the concentrations of Pb(Ⅱ), Cd(Ⅱ), and Cu(Ⅱ) ions in the supernatant solution were determined by the atomic absorption spectrometer. As the results, the adsorption equilibrium of Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) ions were reached to equilibrium by shaking for about 30∼40minutes. Then adsorptivities were 84%, 79% and 65% respectively.

      • KCI등재

        언양 자연 집단내 Drosophila melanogaster의 유해 유전자 빈도 분석

        김영필,최영현,유미애,이원호 한국환경과학회 1996 한국환경과학회지 Vol.5 No.1

        The genetic variabilities of second chromosomes of Drosophila melanogaster concealed in O^n-yang natural population have been analyzed by the Cy//Pm method and an allelism test during two years (1993-1994). The mean frequencies of deleterious(lethal and semilethal) genes in O^n-yang natural population were estimated to be 23.97% in 1993 and 27.15% in 1994, respectively. The allelism rates between lethal genes in the population were 0.654%(1993) and 1.429%(1994). The mean values of elimination by frequencies of deleterious genes and allelism rates were 0.0004(1993) and 0.0010(1994), respectively. The frequencies of phenotypic sterility of males in 1994 were estimated to be 1.95%, and thoses of genotypic sterility of females and males were estimated to be 1.54% and 2.31%, respectively.

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