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김수현 ( Soo Hyun Kim ), 이아름 ( Ahreum Lee ), 김수지 ( Suji Kim ), 김경조 ( Kyeong Jo Kim ), 권오준 ( Ojun Kwon ), 최준영 ( Joon Young Choi ), 구진숙 ( Jin Suk Koo ), 노성수 ( Seong-soo Roh ) 대한본초학회 2017 大韓本草學會誌 Vol.32 No.4
Objectives : Advanced glycation end products (AGEs) is bind formation of glucose and protein. Acceleration of AGE formation during hyperglycemia is associated with the pathogenesis of diabetic complications and causes kidney and skin damage. The aim of this study was investigated the AGEs inhibitory activity and antioxidant activity of water extracts from young persimmon (YP) and heated young persimmon (HYP). Methods : Paeoniae Radix Alba (YP) is prepared by heating with 30% ethanol. AGEs formation inhibitory activities of YP and HYP measured using bovine serum albumin. To evaluate the protective effects of YP and HYP in diabetic rats induced with streptozotocin (STZ) and methyl glyoxal (MGO), SD rats were distributed into four groups; normal mice (Nor), AGEs-induced rats (Con), AGEs-induced rats treated with 100 ㎎/㎏ YP (YP), AGEs-induced rats treated with 100 ㎎/㎏ heated YP (HYP) for 3weeks. Heated young persimmon respectively decrease AGEs construction. Results : YP and HYP administration inhibited the biomarkers of AGEs in serum, kidney and skin tissues. AGE-induced rats revealed that the significant decreased collagen however, heat processing methods of young persimmon up regulated inhibits AGEs-induced collagen decrease. The expressions of AGEs were decreased in YP and HYP treated group compared with the control group in tissues. It specifies that HYP has potential to serve as a positive regulator of via AGEs path way. Conclusion : It has proposed that may have an improvement effect on diabetic complications, heated young persimmon has AGEs inhibitory excellent activities and antioxidant effect.
The food components of red sea bream(Pagrus major) cultured in copper alloy(brass) net(BN) and nylon net(NN) cages for nine months were investigated. The body weight was 234.9g at the beginning of the culture(the young fish), and then 692.1g(BN group) and 549.3g(NN group) at the fish cultured for nine months(the nine-month culture fish). The moisture content of the edible portion of the fish was higher in the young fish than in the nine-month culture fish. On the contrary, the lipid content was higher in the latter (9.1-10.6%) than in the former (7.6%). The lipid content in the nine-month culture fish was slightly higher in the BN group compared to the NN group. There was little difference in protein content between the young fish and the nine-month culture fish, or between the BN and NN groups. There was a slightly higher level of copper content in the liver (5ppm in the young fish and 5-6ppm in the nine-month culture fish) compared to the edible portions (1ppm in the young fish and 3-4ppm in the nine-month culture fish), but no difference was evident between the BN and NN groups. The prominent fatty acids were 16:0, 18:1n-9, 22:6n-3, 16:1n-7, 18:2n-6, 20:5n-3, and 18:0 in the edible portions of the young and cultured fish. The n-3 fatty acid content was slightly richer in the BN group.
Carcinoma of the lung is generally considered as a disease of middle age and elderly. But lung cancer is now so prevalent that patients below the age of 40 years must be increaseing. We reviewed the records of 483 lung cancer patients who had been diagnosed in the department of internal medicine of Seoul National University Hospital from March 1984 to February 1986, and the clinical features of the young patients under 40 years were compared with those of the control group patients over 40 years. The results are summarized as follows; 1) Seven percent of 34 cases of 483 patients were belong to the young age group patients (less than 40 years). The youngest patient was 22 years old. 2) Male to female ratios of young group and the control group were 3.25:1, 5.9:1 respectively (p$gt;0.05). 3) The mean duration of symptoms from the onset to the definite diagnosis was 2.7 months in young group and 2.3 months in the control group (p$gt;0.3). 4) The most common initial symptoms in the young group were dyspnea (26.5%), hemoptysis (20.5%), cough or sputum (20.5%), chest pain (8.8%) which were also the most common initial symptoms in the control group. (p$gt;0.25) The incidence of superior vena cava syndrome was significantly higher in the young age group (23.5%) than in the control group (7.1%) (p$lt;0.05). 5) In the young group, the proportion of adenocarcinoma (35%) was significantly higher than that of the control group (18%) (p$lt;0.05). 6) The proportion of smoker was significantly lower in the young age group (13 cases, 38.2%) than in the control group (77.7%). The histological type of 13 smokers of the young group was squamous cell carcinoma in 12 cases and adenocarcinoma in 1 case. 7) All non-small cell lung cancer patients in young group were belong to stage Ⅲ. 8) Distant metastasis rate of the young group (74%) was significantly higher than that of the control group (54.8%) (p$lt;0.05).
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The purpose of this study was to investigate the effects of parental imperative verbal control mode and young children's self-control on problem behaviors. Teachers and parents of 3-5 aged young children attending 5 kindergartens located in Cheongju responded the questionnaires. The research model was tested through path analyses using AMOS 7.0 program. The results of this study were as follows : First, mother's imperative verbal control influenced on young children's self-control, and young children's self-control had a good effect on hyperactive-aggression. There was no significant direct effect of mother's imperative verbal control on young children's hyperactive-aggression, but the effect of mother's imperative verbal control on young children's problem behaviors was mediated by young children's self-control. Father's imperative verbal control had no effect on children's self-control and hyperactive-aggression. Second, parental imperative verbal control and children's self-control did not show any significant influence on children's worried-anxiety.
The purpose of the study was to provide the basic materials of scientific educational program suitable to young children by showing the effects of life science teaching on young children's naturalist intelligence and scientific inquiring ability. Research issue 1. What are the effects of life science teaching on young children's naturalist intelligence? Research issue 2. What are the effects of life science teaching on young children's scientific inquiring ability? 2-1. What are the effects of life science teaching on the children's ability to predict of the children's scientific investigation? 2-2. What are the effects of life science teaching on the children's ability to observe of the children's scientific investigation? 2-3. What are the effects of life science teaching on the children's ability to classify of the children's scientific investigation? 2-4. What are the effects of life science teaching on the children's ability to measure of the children's scientific investigation? 2-5. What are the effects of life science teaching on the children's ability to discuss of the children's scientific investigation? The target groups of the study are a class of twelve children of 4 years old who are total 24 students of two different day care centers in Daejeon City. The children of the experimental group, A, in one daycare center have been instructed with the life science teaching for the science activity for 16 weeks, while the control group, B, in a different day care center, have been instructed the standard of child care process for the science activity. The measurement of young children's naturalist intelligence and scientific inquiring ability had been used 'the multiple intelligence test (PMIT-E) for preschoolers' and 'the testing instrument of scientific inquiring ability'. To know the difference of their naturalist intelligence between the experimental group and the control group, the research material collected through such a testing instrument had been verified the corresponding sample, t and to know the difference of their scientific inquiring ability, the significance had been verified through the application of ANCOVA. The crucial result on the study is as follows. Firstly, the children who were instructed with the life science teaching statistically significantly improved the young children's naturalist intelligence more than the children who were not instructed with the life science teaching. Therefore, life science teaching has a positive effect on improving young children's naturalist intelligence. Secondly, the result after the study is that the life science teaching has a considerable effect on scientific inquiring ability. The experimental child group experienced a significantly noticeable point increase statistically compared to that of the opposing group. Therefore, life science teaching has a positive effect on improving young children's scientific inquiring ability. Therefore, life science teaching has an effective class on young children's naturalist intelligence and scientific inquiring ability.
This study aimed to examine how the welfare environments of early childhood teachers and individual variables of young children influence young children`s emotional competence. To this end, a survey was conducted among children aged between three and five years and teachers at a childcare center in Gyeonggi-do, and a multi-level data analysis using HLN 7.0 was carried out to analyze this study data. The results of this study are as follows: First, the study showed that young children`s emotional awareness of themselves and others, as well as their emotional control, depended on the children`s gender and their teachers` job-related stress. Second, the study showed that young children`s emotional vocabulary and empathy depended on the children`s gender and their teachers` academic background. Third, the study showed that young children`s emotional expressiveness depended on the children`s gender, emotionality, and organizational commitment, and their teacher`s job-related stress. The results of this study are relevant to the welfare of early childhood teachers, who have a major influence on educational institutions for young children, and lay the groundwork for future educational policies.
본 연구는 G지역에 거주하는 유치원 원아 70명을 대상으로 꽃과 채소 가꾸기 활동이 유아의 정서지능 및 행복감에 어떠한 영향을 미치는 지를 알아보기 위한 목적으로 이루어졌다. 이를 위하여 두 가지 연구문제를 설정하였다. 첫째, 유치원에서의 꽃과 채소 가꾸기 활동이 유아의 정서지능에 미치는 영향은 어떠한가? 둘째, 유치원에서의 꽃과 채소 가꾸기 활동이 유아의 행복감에 미치는 영향은 어떠한가? 연구결과는 다음과 같다. 첫째, 유치원에서의 꽃과 채소 가꾸기 활동은 실험집단과 통제집단 비교에서 정서지능 하위영역인 자기인식, 감정조절, 타인인식, 대인관계 모든 영역에서 유의한 차이가 있는 것으로 분석되었다. 둘째, 유치원에서의 꽃과 채소 가꾸기 활동은 실험집단과 통제집단 비교에서 행복감 하위영역인 부모관계, 교사관계, 인지 및 성취, 몰입, 정서, 건강, 생활만족 영역에서 유의한 차이가 있었다. 이러한 결과를 볼 때 유아의 정서지능과 행복감 증진을 위해 꽃과 채소 가꾸기 활동의 체험들이 적절하고 의미 있는 교육활동으로 현장에 적용해 볼 수 있음을 시사해 주고 있다. The purpose of this study was to find out how flower and vegetable growing activity will have an influence on young children's emotional intelligence and happiness. The subjects of study were 70 young children in the age group of 5 years at G kindergarten and H kindergarten. Among those 70 young children, each 35 young children were allocated to both experimental group and control group, respectively and then flow growing activity and vegetable growing activity were classified for separate allocation. The findings were as follows: First, flower and vegetable-growing activity had a positive influence on young children's emotional intelligence. In particular, looking at the effect of emotional intelligence by sub-area, it was analyzed that there was a significant statistical difference in self-recognition, emotion adjustment, recognition of others, interpersonal relationship, and all areas-sub area of emotional intelligence between experimental group and control group. Second, flower and vegetable-growing activity had a positive influence on young children's happiness. Looking at the effect of happiness by sub-area, it was appeared that there was a significant statistical difference in young children parent relationship, young children-teacher relationship, peer relationship, young children's recognition and achievement, immersion, emotion, health, and satisfaction in life -subarea of happiness-between experimental group and control group, but no significant statistical difference in spirituality.
( Eun Hye Lee ), ( Ah Young Leem ), ( Sang Hoon Lee ), ( Joo Han Song ), ( Song Yee Kim ), ( Kyung Soo Chung ), ( Ji Ye Jung ), ( Moo Suk Park ), ( Young Sam Kim ), ( Joon Chang ), ( Young Ae Kang ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Background: The prevalence of nontuberculous mycobacteria lung disease (NTM-LD) is increasing worldwide. However, there is limited information about the NTM-LD of young age people. Methods: Patients diagnosed with NTM-LD at severance hospital between January 2006 and December 2016 were retrospectively reviewed. Clinical characteristics and microbiologic features of patients under 40 years were compared with patients over 40 years. Results: Total 906 patients were identified NTM-LD. Of these, 29 patients (3.2%) were under 40 years of age (young age group) and the remaining 877 were over 40 years of age (old age group). Mean age of the two groups were 32 (IQR 24-33) and 64 (IQR 56-72), respectively. Female was predominant in both groups and about half of the patients had a history of tuberculosis (51.7% vs.51.5%, p=0.984). 7 patients (24.1%) of the young age group had malignancy history and among them, 6 patients were hematologic cancer who subsequently received bone marrow transplantation. The proportion of the nodular bronchiectatic form of NTM-LD is significantly higher in old age group (67.5%) compared to young age group (31.0%) (p=<0.001). M.avium complex (MAC) was the most common etiologic organism in both groups, however, it was less common in the young age group (44.8% vs. 65.3%, p=0.023). Identification of M.abscessus complex (MABC) was higher in young age group although statistically insignificant (24.1% vs. 17.0%, p=0.318). Conclusion: This study could help to better understand the characteristics and microbial features of NTM-LD of young age people.
본 연구는 식물체험과 연계한 동시감상이 유아의 정서지능과 정서창의성에 미치는 효과를 알아보기 위하여 경북 G시의 어린이집 유아 만 4세 39명을 대상으로 실험집단과 통제집단으로 분류하였다. 여러 선행연구를 참고하여 식물체험과 연계한 동시감상 계획안을 작성하였으며 측정도구는 정서지능 검사와 정서창의성 검사로써 사전·사후 검사를 하였다. 자료처리 및 분석은 SPSS 16.0을 이용하여 공변량분석(ANCOVA)을 실시하였다. 연구결과 첫째, 식물체험과 연계한 동시감상을 한 실험집단과 하지않은 통제집단 간의 유아의 정서지능(자기인식 표현력, 자기조절능력, 타인인식능력, 대인관계능력)에 통계적으로 유의미한 차이를 나타내었다. 둘째, 식물체험과 연계한 동시감상을 한 실험집단과 하지않은 통제집단 간의 유아의 정서 창의성(신기성, 준비성, 효율성, 솔직성)에 통계적으로 유의미한 차이를 나타내었다. This study is intended to know the effects of children`s verse activities through experience related plants on emotional intelligence and emotional creativity of young children. 39 young children who are four years old of child care center in G city were participated to analyze this study. 20 children were the experimental group and 19 children were the comparative group. To measure emotional intelligence of young children, Byeong-nae Lee`s Emotional Intelligence Checklist(1997) and Ji-hye Back`s Test(1991) is used. SPSS 16.0 programs were used. The results are as follows. The first, emotional intelligence of young children who participated in young children`s verse activities through experience related plants was improved, compared with that of young children who did not. The second, emotional creativity of young children who participated in young children`s verse activities through experience related plants was improved, compared with that of young children who did not.
Objectives: Although there have been several reports that described characteristics for young age stroke, information regarding very young age (18–30 years old) has been limited. We aimed to analyze demographic factors, stroke subtype, and 3-month outcome in acute ischemic stroke patient who have relatively very young age in multicenter stroke registry. Methods: We evaluated all 122 (7.1%) consecutive acute ischemic stroke (within 7 days after symptom onset) patients aged 18 to 30 from 17,144 patients who registered in multicenter prospective stroke registry, 1997 to 2012. Etiology was classified by Trial of Org 10172 in Acute Stroke Treatment criteria. Stroke severity was defined as National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was defined by modified Rankin scale (mRS) at 3 months after index stroke. Results: The mean age of all included patients was 25.1±3.7 years and 76 patients (62.2%) were male. The median NIHSS at admission was 4. Considering stroke subtype, 37 patients (30.3%) had stroke of other determined etiology (SOD), 37 (30.3%) had undetermined negative evaluation (UN) and 31 (25.4%) had cardioembolism (CE) were frequently noted. After adjusting age, sex and variables which had P<0.1 in univariable analysis (NIHSS and stroke subtype), CE stroke subtype (odds ratio, 4.68; 95% confidence interval, 1.42–15.48; P=0.011) were significantly associated with poor functional outcome (mRS≥3). Conclusion: In very young age ischemic stroke patients, SOD and UN stroke subtype were most common and CE stroke subtype was independently associated with poor discharge outcome.