한국인의 연, 망간, 알루미늄 및 실리콘의 혈중 농도

김정만,안정모,김원술,김정일,신해림,정갑열,김준연 동아대학교 산업의학연구소 2000 산업의학연구소 논총 Vol.- No.5

Blood Lead, Manganese, Aluminium and Silicon Concentrations in Korean Adults Jung Man Kim, Jung Mo Ahn, Won Sul Kim1), Jung Il Kim2), Hai Rim Shin, Kap Yeol Jung2), Joon Youn Kim Department of Preventive Medicine, College of Medicine and Industrial Medicine Research Institute. Dong-A University Department of Health Care, Handong University Sunlin Presbyterian Hotpital1) Department of Occupational Medicine, College of Medicine, Dong-A University2) 0bjectives : This study was performed to determine the reference values of blood lead, manganese, aluminium, and silicon in healthy adults. Methods : The subjects were 132 (67 male and 65 female), and classified to three age groups (≤39,40∼49, and 50≤). Hood lead, manganese and aluminium were analyzed by atomic absorption spectrophotometer, and blood silicon was analyzed by direct current plasma optical omission spectrometer. Results : Blood lead levels(geometric mean, S.D) were (3.49, 1.70) ㎍/dL in male auld (3.04, 1.65) ㎍/dL in female, but the difference is not significant, and there was no significant difference between age groups. Mean blood manganese level was 0.99±0.41㎍/dL, and there was no significant difference between sex or age groups. Mean blood aluminium level was 0.59±0.35㎍/dL and there was no significant difference between sex or age groups. Mean blood silicon level was 54.41±27.64㎍/dL in male and 43.34±23.51㎍/dL in female, and the level in male was significantly higher than that in female (p〈0.05). There was significant difference between age groups, and the oldest showed the highest level in male (p〈0.05), but no significant difference between age groups in female. Conclusions : Authors hope that this study would provide basic data for determininig reference values and evaluating health effects.

Analysis of VolP-Associated Accounting based on Quality-Based Billing

Jung,Youn-Chan 가톨릭대학교 자연과학연구소 2005 자연과학논문집 Vol.26 No.-

Existing accounting functions on the AAA architecture mainly deal with metering connection time between set up and tear down. This paper presents the VolP-associated accounting architecture which enables quality based billing. The NAS functions as an end-user server to collect accounting packets on a real-time basis and as an accounting client to send a batch to the AAA server. In order to explore the operational burden of placing the function of VolP-associated data collection on the NAS, we will develop an analytical model to investigate the effects of the frequency of accounting packet generation, the number of active devices, and NAS processing capabilities on the performance of the packet loss probability and the packet buffering delay at the NAS buffer. Then, we discuss these results focused on the maximum number of active devices the NAS can accommodate for a certain condition.

Genetic Toxicity Test of Nanosilica by Comet assay and Mouse Lymphoma Assay

Youn?Jung Kim(김연정),Han Seam Choi(최한샘),Dong Ge Ra Mi Moon(문동그라미),Ji Hee Kim(김지희),Hye Gyeong Jo(조혜경),Jae Chun Ryu(류재천) 환경독성보건학회 2007 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

Awareness of Space as a Theatrical Dramaturgy and Divided Self in Brian Friel’s Plays

( Jung¸ Youn Gil ) 동국대학교 영어권문화연구소 2012 영어권문화연구 Vol.5 No.2

Brian Friel plays communicate not only through words but also through the non-verbal use of space ― both the geographical places in which plays are set and the ways stage space is used. The circumstance of place is always a highly pertinent consideration in any discussion of Irish literature. I try to establish the relevance of a apposite attention to the question of place in Friel plays and propose to see it as an attempt to reveal awareness of place and divided self. The discussion of the paper centers on ‘the problem of space.’ Through this attempt, I examine Friel’s treatment of place as the theatrical dramaturgy in his plays in terms of the geographical space partition and the stage space and asserts that his ‘awareness of place’ reveals the cognitive mapping of Ireland's ‘divided self’. In geographical respect, Ballybeg is emblematic of Ireland and a part of Ireland rather than any one specific village in that area. In this respect Ballybeg represents an effort, at the wider application of a place, towards some kind of local universality. In dramaturgy, the experimental stage spaces are employed to deconstruct the reality Friel has created within the world of Ballybeg as well as its external reality. I draw the conclusion that his attempts to map the pain of de-mythologizing both personal and public identities, facing up to lost fantasies to the individual and the nation. A focus on space particularly connected to theatrical dramaturgy(aesthetics) offers fresh interpretations of the texts and, far from narrowing the significance of Friel’s work, opens it up to some of the major intellectual issues of present Ireland.

고정역할치료가 초등학생의 개인구념 및 대인불안에 미치는 효과

차윤정(Cha Youn-Jung),안이환(Ahn Ie-Hwan) 경성대학교 인문과학연구소 2009 인문학논총 Vol.14 No.1

본 연구의 목적은 Kelly(1955)의 고정역할치료(Fixed-Role theory)가 대인불안이 있는 초등학생의 개인구념(Personal Construct) 및 대인불안에 미치는 효과를 검증하는 데 있다. 본 연구의 가설을 검증하기 위하여 부산시내 K초등학교 5학년 5개 학급 가운데 대인불안검사(음정순, 2003)의 상위 15%에 해당하는 학생 18명을 선발하여 각각 9명씩(여 5, 남 4) 실험집단 및 통제집단으로 설정하였다. 본 연구에서 사용된 고정역할 치료는 Kelly가 2주 동안 실시한 6회기의 고정역할치료 프로그램을 본 연구자가 재구성 하였다. 고정역할치료 프로그램은 4주 동안, 주 3회 총 10회를 연구자의 교실에서 방과 후 시간을 이용하여 실시되었다. 이에 따른 본 연구의 결과는 디음과 같다. 첫째, 고정역할치료 프로그램을 실시한 실험집단의 개인구념은 통제집단에 비해 통계적으로 유의미하게 향상되었다. 둘째, 고정역할치료 프로그램은 실험집단 아동의 6가지 대인불안(일반적 대인불안, 집단·사회적 대인불안, 친구에 대한 대인불안, 특정인에 대한 대인불안, 이성에 대한 대인불안, 미지인에 대한 대인불안) 가운데 미지인에 대한 대인불안을 제외한 5개 영역애서 매우 유의미한 효과가 나타났다. 따라서 고정역할치료는 초등학생의 대인불안에 대한 개인구념의 변화를 통해 불안을 감소시킬 수 있는 새로운 방법임이 확인되었다. The prnpose of this study is proving the effect of fixed-role theory at elementaIy students' individual construction and interpersonal anxiety. To prove these assumptions, each 9 students are categorized into experimented group and controlled group and the 18 subjects are from K elementary school in Busan. Before taking the program, two groups had individual construction test through interpersonal anxiety test and latticed role-construction. Based on Kelly’s (1955) fixed-role theory program taken 2 weeks in sixth fixed-role thoory program, the researcher, myself, reorganized the program with the six sub-factors of interpersonal anxiety analyzed to know the symptoms of interpersonal anxiety by Eum jung-soon(2003). Fixed-role thoory program was experimented 3 times a week, 10 times in total for 4 weeks with the subjects from experimented group after school in researcher’s class. The conclusion of this study is as below. First, the experimented group’s individual construction experimented fixed-role theory program considerably improved. Second, interpersonal anxiety of experimented group taken fixed-role theory program considerably decreased except the interpersonal anxiety with strangers which is a sub-factor.

치매방지 작업기구 사용이 항산화효소 활성에 미치는 영향

조경혜,박정은,윤지윤,문세보,박효영,정인옥,이정원 서울여자대학교 자연과학연구소 2001 자연과학연구논문집 Vol.13 No.-

We developed an occupational therapy tool to maintain and improve the cognitive function for the elderly who have senile dementia. 86 elderly people took a mininal mental state examination (MMSE) for the therapy to perform the occupational therapy, and divided into three groups based on avarage ages and MMSE values. The occupational therapy was treated three times per week for 10 weeks. The results showed that there were significant differences in the performing scores before and after the treatment ; the scores for the occupational therapy were increased significantly (p<0.001) and the performing time was shortened from 6-week throughout 10-week regimen. This study was to examine the effect on the activity of antioxidant enzymes by occupational therapy. The activities of antioxidant enzymes such as catalase, Glutathion-6-phosphate dehydrogenase (G6PDH), and superoxide dismutase (SOD) were increased to the normal standard by the occupational therapy for the elderly having dementia. The recovery of activities of antioxidant enzymes was obvious in severe demented elderly compared to those in normal or mild demented elderly. These results suggest that the occupational therapy had an beneficial effect on the protection against the oxidative stress especially for severe demented elderly, and the occupational tool need to be modified so as to improve the protection against the oxidative stress for normal and/or mild demented elderly.

한국전통생활문화에 관한 고찰

이숙,홍윤호,신윤숙,신효식,한경미,최정미,김은정 全南大學校家政科學硏究所 2002 生活科學硏究 Vol.12 No.-

This study is objected on preliminary research for more scientific and wider studies on the Traditional Living Culture of Korea. For this purpose, studies about clothing, food, home management, Traditional Living Culture were reviewed and analysed. The results were as follows : First, Clothing culture studies concentrated on ritual clothings, Second, Food Culture studies included history of traditional food development and recipes. Third, in the field of home management value system, attitudes and parent-child relations were studied,

정신분열병과 Glutathione S-Transferase M1유전자 다형성

배치운,조자현,김연주,김태석,김정진,이창욱,이수정,전태연,이철,백인호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : This study aimed to test the possible association between Glutathione S-Transferase Ml gene (GSTMl) variants and schizophrenia. Methods : One hundred and eleven inpatients with schizophrenia and 130 healthy controls were recruited. Genotyping was performed by polymerase chain reaction-based method. Results : The GSTMl null genotype was significantly more frequent in patients with schizophrenia than in controls (p=0.014, odd ratio=1.93, 95% confidence interva1=1.115-3.351), while GSTMl genotype vahants were not associated with either tardive dyskinesia (TD) or total Abnormal Involuntary Movement Scale (AIMS) scores. Conclusion : The present study suggests that the GSTMl polymorphism may confer susceptibility to the development of schizophrenia but not to TD, at least in Korean population.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.