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정혜진;김현태;김유선;정현걸;강윤경;문정섭 인제대학교 2011 仁濟醫學 Vol.32 No.-
Eosinophilic gastroenteritis is a rare disorder of unknown etiology characterized by presence of gastrointestinal symptoms, eosinophilic infiltratio n of one or more parts of gastrointestinal tract without involvement of other organs and absence of parasitic infestation. The clinical presentation depends on the extents and depths of eosinophilic infiltration. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. We report a case of eosinophilic enterocolitis in a 55-year-old female presented with abdominal pain and watery diarrhea resulting in recurrent acute renal failure.
응집제 Ceramic-Zeolite type과 황토를 이용한 Microcystis aeruginosa 제거에 관한 연구
박홍기,정은영,이유정,정종문,최식영,홍용기 한국환경과학회 2002 한국환경과학회지 Vol.11 No.4
For the proposal of Microcystis aeruginosa control technique by coagulants, removal effects of coagulants were carried out using isolated strain and collected water bloom of M. aeruginosa on Downstream of the Nakdong River. Both of purified and field-collected M. aeruginosa were entirely sedimented by the addition of the coagulant Ceramic-Zeolite type Co 100 (1.5 mg/l) within 24 hr, but Yellow loess (10 mg/l) was less effective for the removal of M. aeruginosa within 24hr. Thus it was concluded that Ceramic-Zeolite type Co 100 was the most effective coagulant.
유용성 도료와 수용성 도료의 유해성 비교에 관한 연구 : 자동차 보수용 도료를 중심으로
권은혜,김광식,오정룡,최정근,정윤석,이유진,김은아,송세욱,정호근 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1
The purpose of this study is to substitute water-based painting materials for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters. This study assessed the exposure of organic solvents to the painters using water-based and solvent-based painting materials and compared compositions, painting processes and the health hazards of the application of these alternative painting materials. The results of this study are as follows. 1. solvent-based painting materials used in motor-repairing process consist of various organic solvents, which consist primarily of toluene, xylene, ethyl benzene, ethyl methyl bezene, trimethyl bezene, ethyl acetate, butyl acetate, methyl isobutyl ketone, 2-ethoxy ethanol, 2-ethoxy ethyl acetate and toluene-2.4-diisocianate and the others. These organic solvents are know as health-hazardous substances. But water-based painting materials are high-solid, low-solvent ones and consist of such two organic solvents as 2-butoxy ethanol and 2-heptanone and the others. 2. The painters using solvent-based painting materials in motor-repairing process are exposed to various organic acetate, methyl isobutyl ketone, trimethyl benzene, 2-ethoxy ethanol, and 2-ethoxy ethyl acetate. But the painters using solvent-based ones are only exposed to 2-butoxy ethanol and 2-heptanone. 3. By using water-based painting materials in stead of solvent-based painting materials containing health-hazardous organic solvents, the exposure of such organic solvents in the painter's breathing zone can be largely prevented. 4. This study recommends water-based painting materials as substitutes for the current solvent-based ones used in motor-repairing process to minimize the exposure of organic solvents to the painters.
사회성 훈련 프로그램이 발달장애아동의 사회성 및 적응행동에 미치는 효과
유은희,양정남,이숙자 동신대학교 2005 論文集 Vol.15 No.-
The Effects of a Social Skills Program on Improving Sociability, and Adaptive Behaviors of Children with Developmental Disabilities. The purpose of this study was to investigate the effects of a social skills program on improving social skills, and adaptive behaviors of children with developmental disabilities. A total of nine children at the Language Therapy Center for children and adolescents in Gwangju Metropolitan City participated in this study with the consent from their parents. The research was conducted following one-group pretest-posttest design, a preexperimental design. A social skills program was implemented once a week with 90 minutes per session for 15 weeks. The effects of the program were evaluated by administering Social Maturity Scale, and Adaptive Behavior Scale before and after the program. The results showed that the scores in social maturity, and adaptive behavior scales, respectively, increased from pretest to posttest. This study concluded with a discussion on the implications of social skill programs for improving social skills, and adaptive behaviors of children with developmental disabilities in the field of social welfare. Implications and suggestion for future studies was discussed.
Dihydroflavonol 4-reductase 유전자를 이용한 담배의 형질전환
유정아,이원숙,이주안,김영채,박영두 경희대학교식량자원개발연구소 2006 硏究論文集 Vol.25 No.-
본 연구는 화색과 관련된 DFR 유전자를 Agrobacterium을 이용한 형질전환 방법으로 담배(Nicotiana tabaccum L.)에 형질전환 시키기 위해 수행되었다. 이를 위하여 배추의 DFR 유전자를 CaMV 35S promotor와 nos terminator를 운반하는 식물 발현용 vector, pCAMBIA 1302에 삽입하였다. 재조합된 벡터 pCAMBIA 1302-DFR은 Agrobacterium tumfaciens LBA4404를 이용하여 담배 식물체 잎 절편체를 형질전환한 후 MS 배지에 1.5 mg·L^(-1) BA, 50 mg·L^(-1) hygromycin 및 200 mg·L^(-1) cefotaxim이 첨가된 1차 선발배지에서 신초를 유도하였다. 유도된 신초는 100 mg·L^(-1) hygromycin과 200 mg·L^(-1) cefotaxim이 첨가된 2차 선발 배지에서 뿌리를 유기하였다. 뿌리가 형성된 재분화 개체는 온실에서 재배하였으며 재배된 담배로부터 genomic DNA를 추출하고 DFR 유전자의 담배 genome내로의 전이여부를 hygromycin primer를 이용하여 PCR 방법으로 확인한 바 형질전환 개체에서 예상했던 365 bp 단편을 볼 수 있었으나 형질전환을 시키지 않은 식물체에서는 PCR 산물을 확인 할 수 없었다. PCR 검정으로 확인된 담배는 화색변이 여부를 관찰하기 위해 온실에서 재배 중에 있다. Dihydroflavonol 4-reductase (DFR) gene was introduced into tobacco (Nicotiana tabaccum L.) plants using Agrobacterium mediated transformation. To introduce this gene, DFR gene was cloned into plant binary vector, pCAMBIA 1302, harboring CaMV 35S promotor and nos terminator. After infection with Agrobacterium tumefaciens LBA4404 containing pCAMBIA 1302, transformed shoots were induced from first selection medium (MS medium + 1.5 mg·L^(-1) BA + 50 mg·L^(-1) hygromycin + 200 mg·L^(-1) cefotaxim). To confirm the transfer of DFR gene in the genome of tobacco plants, PCR was conducted using primers of the hygromycin gene. A PCR fragment of 365 bp was obtained from each transformed plants, which is the predicted size of the hygromycin gene but not from nontransformed plants. Transformed tobacco plants are growing in the greenhouse to analyze phenotypic variation, especially flower color.
유구치 상아질의 각 부위에 적용된 수종의 복합레진 접착제의 미세인장접착강도에 관한 연구
유정은,최영철,최성철,박재홍 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3
본 연구는 유구치 상아질의 각기 다른 부위(표층부, 심층부, 치경부)에서 복합레진 접착제의 접착강도를 비교, 평가하기 위하여 임상에서 흔히 사용하고 있는 서로 다른 4종의 접착방식(3-step total etch: 1군, 2-step total etch: 2군, 2 step self-etch: 3군, all-in-one: 4군)을 적용하고 복합 레진(Light-Core™ Core Build-Up Composite)을 적층한 후, 미세인장접착강도를 비교하였을 때 다음과 같은 결과를 얻었다. 1. 접착방식간의 비교에서 레진의 접착방식에 따른 상아질 각 부위에서의 미세인장접착강도는 제 1군이 표층부에서 뚜렷이 높았으나(p<0.05) 2, 3, 4군은 부위에 따른 차이가 없었다. 2. 부위별 미세인장접착강도를 비교하여 보았을 때 상아질 표층부에서의 미세인장접착강도는 레진의 접착 방식간에 차이가 없었으나, 심층부에서는 2군, 3군, 4군 및 1군의 순으로 나타났고(p<0.05), 치경부에서는 2군과 3군이 1군과 4군에 비하여 현저히 높았다(p<0.05). The purpose of this study was to evaluate the micro-tensile bond strength (μTBS) of four luting resin to regional dentin of human primary teeth. Dentin from non-carious primary molars were prepared from different regions(s, superficial dentin; d, deep dentin; c, cervical dentin), and divided into groups based on anatomical locations and types of luting resins(Scotchbond Multi-purpose: SB ; One-Step: as ; AdheSE Bond: ASE ; G-Bond : GB) : SB-s, SB-d, SB-c; OS-s, OS-d, OS-c; ASE-s, ASE-d, ASE-c ; GB-s, GB-d, GB-c. Luting resins were used according to the manufacturers' instructions, to bond Light-Core™ Core Build-Up Composite) to the exposed dentin specimens in the light-curing mode. After storage for 1 day, μTBS was tested at a cross-head speed of 1 mm/min. Data were analyzed with T-test and two-way ANOVA. The bonding interface and fractography analyses were performed with SEM. The results were as follows : 1. μTBS to superficial dentin was significantly higher than to deep dentin for SB(p<0.05). But there were no significant differences in regional μTBS among as, ASK GB(p>0.05). 2. There were no significant differences in μTBS to superficial dentin among each groups. But, in deep dentin, μTBS of SB-d was significantly lower than those of OS-d, ASE-d, and GB-d(p<0.05). μTBS of OS-d was significantly higher than those of GB-d(p<0.05), but there were no significant differences in μTBS of ASE-d. There were no significant differences among μTBS of ASE-d, OS-d, and GB-d.
자폐스펙트럼 장애아동의 의사소통 기술 향상에 관한 단일대상연구의 문헌 분석
정유진,윤현숙 이화여자대학교 특수교육연구소 2014 특수교육 Vol.13 No.1
이 연구는 2007년부터 2013년까지 이루어진 자폐스펙트럼 장애아동의 의사소통 기술 향상을 위한 연구들을 조사하여, 일반적인 특징과 동향을 알아보고, 단일대상연구 증거기반 실제(evidence-based practices: EBP)의 기준이 되는 Horner 등(2005)이 제안한 질적 지표를 기초로 중재방법에 대한 문헌 분석을 실시하였다. 연구 결과, 첫째, 자폐스펙트럼 장애아동의 의사소통 기술 향상을 위한 단일대상연구들의 일반적인 특징을 분석한 결과, 연구대상 측면에서는 3명 이상으로 실시된 연구들이 절반 이상이었고, 연령은 주로 초등연령에서 이루어져 왔으며, 장애정도는 경증-중간 자폐에서부터 중도 자폐에 이르기까지 고르게 이루어져 왔다. 연구환경은 여러 기타 외부 환경에서 이루어진 연구들이 절반을 차지하였고, 실험설계는 주로 중다 기초선 설계와 중다 간헐 기초선 설계를 많이 사용했다. 독립변인으로는 다양한 중재방법들이 사용되었으며, 이 중 4편 이상의 논문에서 실시된 중재로는 상황이야기 중재, 보완대체 의사소통 중재가 있었다. 다음으로 종속변인으로는 의사소통 기능 증진의 효과를 본 연구들이 절반 이상을 차지하였다. 둘째, 자폐스펙트럼 장애아동의 의사소통 기술 향상을 위한 단일 대상연구들의 증거기반 실제의 기준이 되는 질적 지표 충족 정도를 살펴본 결과, 질적 지표의 영역별 평균 충족률은 종속변인 96%, 기초선 94%, 대상자 및 환경 91%, 실험통제 및 내적 타당도 91%, 독립변인 78%, 사회적 타당도 64%, 외적 타당도 62% 순으로 나타났다. 또한 각 논문별로 질적 지표의 충족여부를 살펴본 결과 21가지 질적 지표 중 90%에 해당되는 19가지의 질적 지표를 모두 충족시키는 경우는 6편(23%)인 것으로 나타났다. In this study, we investigated literatures done through 2007 to 2013 about the improvement of communication skill in children with autism spectrum disorder. We examined general feature and trends, and performed qualitative analysis based on quality indicator which can be a standard for evidence-based practice(EBP) in single subject research suggested by Horner et al.(2005). In the view of general feature and trends, we first found that more than half studies were performed with three or more children in terms of subject of study, and mainly carried out in the age before 13. Severity of disability was identified evenly from mild and moderate to severe autism. From the side of research environment, more than half studies were performed in many different environments, mostly using multiple baseline design and multiple probe design. Various interventions were conducted as independent variable. Social stories intervention and augmentative and alternative communication intervention(AAC) were employed in more than 4 literatures. In dependent variable, it was confirmed that more that half of studies showed the significant improvement in communication skill. In the analysis of satisfaction level in quality indicator, the average level of areal satisfaction in quality indicator was respectively 96% in dependent variable, 94% in baseline, 91% in subjects and environments, 91% in experimental control/internal validity, 78% in independent variable, 64% in social validity, and 62% in external validity. Besides, among all literatures examined by satisfaction level in quality indicator, 6 literatures (23%) fulfilled the requirements of 19 out of 21 quality indicators.
노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성
유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6
Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.
劉承宰,崔允碩,金正九 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.6
The purpose of the present investigation was to study the stress corrosion cracking (SCC) properties of environmentally friendly Bi-brasses in Mattsson's solution (0.05M copper sulfate and 0.5M ammonium sulfate, pH 7.4) at room temperature. Three unleaded brasses with Bi content ranging from 1 to 3 wt% and a conventional leaded brass for comparison were investigated. The effect of Bi on SCC of unleaded brasses was studied through polarization test, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM, energy dispersive spectroscopy (EDS) and slow-strain-rate test (SSRT). Potentiodynamic polarization studies indicated that the corrosion resistance of Bi-containing brasses was improved as the content of Bi, which showed a passivating characteristic in Mattsson's solution, increased. The Pb- and Bi-containing brasses presented an inductive behavior on impedance data in low frequency region at the open-circuit potential (OCP). Such behavior could be attributed to the adsorption process on the alloy surface. The observed dezincified layers after SSRT should be particularly good initiators of SCC as they could induce tensile stress. As the content of Bi increased, the thickness of dezincified layer and the volume fraction of preferentially attacked Β phase decreased, therefore, SCC resistance of the Bi-containing brasses was improved.