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Potential Application of Cells from htPA Transgenic Pig's Somatic Cells
You-Mi Jo,Kyung-Woon Kim,Deug-Woo Han,Byong-Chul Yang,Dong-Kyo Kim,Eun-Ju Chung,Myoung-Seob Choi,Ji-Hyun Lim,Mi-Yun Oh,Su-Jin Jo,Jin-Ki Park,Won-Kyong Chang,Hak-Jae Chung 한국동물생명공학회(구 한국동물번식학회) 2012 발생공학 국제심포지엄 및 학술대회 Vol.2012 No.1
You Jin Lee,Jae Min Hwang,Ji Soo Hong,Ye-Won In,Hyung-Yong Cho 한국산업식품공학회 2017 학술대회 및 심포지엄 Vol.2017 No.11
In a previous study, it was reported that enzymatic hydrolysis under pressurization could be a new method which could produce arginine dipeptide and free amino acid in anchovy hydrolysate as salty enhancer at optimal condition. Powder is more efficient than liquid in terms of transport and storage stability. For the purpose of producing spray dried powder of various salt contents was investigated the effect of different salt concentration of anchovy hydrolysate on spray dried powder properties. The anchovy hydrolysate of various salt contents(in the range of approximately 0.7- 19.8% w/w) prepared adding the fish sauce (Dae-Young fish market) at inlet drying air temperatures of 120°C and 140°C. The process yield and physicochemical properties such as moisture content, bulk density, hygroscopicity and the morphology (EDS, XPS, XRD) of the anchovy hydrolysate powder was measured. The glass transition temperatures (Tg) of the powders equilibrated under various water activities were determined using a differential scanning calorimeter (DSC). Different drying conditions and salt concentration could generate anchovy hydrolysate powders with different process yield, bulk density and moisture content. The spray-dried anchovy hydrolysate powder was confirmed by XRD to be a mixture of an amorphous substances and crystalline salts. The energy dispersive X-ray spectrometer (EDS) and X-Ray Photoelectron Spectroscopy (XPS) analysis demonstrated that the surface NaCl concentration of the powders increased with an increasing drying air temperature. Increasing moisture adsorption of the anchovy hydrolysate powders resulted in a Tg reduction. It is suggested that producing spray dried anchovy hydrolysate for the industrial use is the use of the feed salt concentration of not lower than % w/w and inlet air temperature at 120°C, 140°C
(You Cheol Hwang),(Tae Won Lee),(Myung Jae Kim),(Moon Ho Yang),(Chun Gyoo Ihm) 대한내과학회 2001 The Korean Journal of Internal Medicine Vol.16 No.2
N/A Background : It has not been clear whether immunosuppressive therapy favorably influences renal function and proteinuria in IgA nephropathy (IgAN). Angiotensin converting enzyme inhibitor (ACEi) has an anti-proteinuric effect in IgAN. A retrospective study was done to see whether the addition of immunosuppressive therapy to ACEi produces a more excellent anti-proteinuric effect and preserves better renal function than ACEi alone. Methods : A total of 49 patients with proteinuria>1.0 g/day and serum creatinine concentrations<1.5 mg/dL were followed-up from at least 1 year to 9 years. Among them, 25 patients were treated with the combination of cyclophosphamide, prednisolone and ACEi while the other 24 were treated with ACEi alone. Results : The combination therapy or ACEi alone both reduced proteinuria with significant value (the combination group: from 5.74±5.08 to 2.29±2.77 g/day, ACEi group: from 3.85±2.54 to 1.68±1.91 g/day), while no significant differences in reduction of proteinuria were noticed between the two groups. There was no significant elevation of serum creatinine in both groups during follow-up (the combination group: from 0.91±0.20 to 1.03±0.38 mg/dL, ACEi group: from 0.93±0.27 to 0.99±0.37 mg/dL). This study showed no significant differences in the change in slope of 1/serum creatinine levels during the follow-up period between the two groups. Conclusion : We conclude that immunosuppressive therapy may not be beneficial in patients with proteinuric IgAN. ACEi may be a valuable therapeutic agent avoiding serious side effects of immunosuppressive agents.