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Carotid intima-media thickness in hypertensive patients is associated with media wall changes
( Yo Han Park ),( Hyun Woong Park ),( Yong Kyun Kim ),( Ki Hong Kim ),( Jang Ho Bae ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: It is still unknown which layer out of intima (CIT), media (CMT), and intima-media thickness (CIMT) of carotid artery is thickened in patients with hypertension (HTN). We evaluated to see which of the two layers is thicker in patients with HTN and investigate the predictable factors of CIMT. Methods and Results: This is an observational cohort study that consisted of 1,809 patients from 12 hospitals. The carotid images were sent to Korea Research Institute of Standards and Science for core laboratory analysis using specialized software, which can measure intima and media wall thickness. HTN patients (n=1079, 59.6%) were more likely to be older (60.2 years old vs. 53.8 years old, p<0.001) than non-HTN patients. Also, they were more likely to have diabetes, dyslipidemia and higher creatinine level compared to non-HTN patients (n=730, 40.4%). HTN patients showed significantly higher CIMT (0.72±0.17 mm vs. 0.64±0.15 mm, p<0.001), CMT (0.40±0.13 mm vs. 0.35±0.12 mm, p<0.001), and CIT (0.031±0.007 mm, 0.030±0.006 mm, p<0.001) than non-HTN patients. Linear regression analysis showed that HTN (CIMT, β=0.172, 95% CI=0.031-0.072, p<0.001, CIT, β=0.137, 95% CI=0.007-0.024, p<0.001, CMT, β=0.151, 95% CI=0.020-0.053, p<0.001), age, CKD, LDL cholesterol level (>100 mg/dL) were associated with CIMT, CIT, and CMT. On the other hand hs-CRP was only associated with CIMT (β=0.071, 95% CI=0.001-0.042, p=0.040). In HTN patients, age (β=0.283, 95% CI=0.055-0.115, p<0.001), CKD (β=0.184, 95% CI=0.040-0.134, p=0.040) and LDL-cholesterol level (β= 0.120, 95% CI=0.007-0.065, p<0.001) were associated with CIMT. However, age (β=0.425, 95% CI=0.100-0.174, p<0.001) and obesity (β=0.118, 95% CI=0.005-0.063, p=0.023) were associated with CIMT in non-HTN patients. Conclusions: HTN was importantly associated with CIMT in non-symptomatic subjects. The increased CIMT in patients with HTN was due mainly to increased CMT. Age, CKD and LDL-cholesterol level were associated with CIMT in HTN patients. This result suggests that lipid control is important in hypertensive patients in terms of atherosclerosis.
Intravascular Epithelioid Angiosarcoma in the Abdominal Aorta Mimicking an Infected Aneurysm
Woong Ki Park,Kyong Lin Park,Yo Seok Cho,Ahram Han,Sanghyun Ahn,Seung-Kee Min 대한혈관외과학회 2019 Vascular Specialist International Vol.35 No.4
Primary aortic angiosarcoma is very rare, and preoperative diagnosis is challenging with resultant poor prognosis. Angiosarcoma may mimic an infected aneurysm or a mural thrombus. Clinical suspicion of angiosarcoma is vital for an early diagnosis and proper surgical treatment, especially in cases with atypical rapid growth of an aortic abdominal aneurysm with a thrombotic mass. Herein, we report a case of angiosarcoma in the abdominal aorta mimicking an infected aneurysm and present computed tomography and positron emission tomography findings.
An Application for Efficient Management of User Created Content in Ubiquitous Fashionable Computer
Yo-Won Jeong,Chul Lee, Ki-Woong Park,Kyu Ho Park 한국차세대컴퓨팅학회 2007 한국차세대컴퓨팅학회 논문지 Vol.3 No.4
The one of important issues for the success ofwearable computer is developing its killerapplications. An application of user created content(UCC) in Ubiquitous Fashionable Computer (UFC)[1], introduced in this paper, is an efficient anduseful tool to create and manage user's multimediacontent. The UFC includes a gesture-based userinterface called iThrow. By using this device, userscan control UFC easily and intuitively. The scenarioof our UCC in the UFC is as follows. First a usercaptures an image by using the camera attached inthe UFC. For editing the captured image, the usersend it to a near kiosk by taking throwing action tothe kiosk, and then the image is displayed in thekiosk. The user can edit the image such as rotationor adjusting picture size, brightness, and contrastby taking various intuitive hand-gestures. Afterediting, if the user takes the throwing action again,the final image is uploaded and registered in hisblog automatically.
혼합원자가 훼라이트 Ca_(1+x) La_(1-x) FeO_(4-y)계의 비화학양론적 조성과 그 물성에 관한 연구
여철현,편웅범,이은석,이성주 연세대학교 대학원 1989 延世論叢 Vol.25 No.1
Perovskite-related oxides of the Ca1+xLa1-xFe4-y system (0.0≤x≤0.5), possessing the K2NiF4 structure, have been prepared and studied by X-ray diffraction, Mohr salt analysis, Mo¨ssbauer effect and electrical conductivity. X-ray diffractions show that the solid solutions of this system have tetragonal or distorted tetragonal K2NiF4 structures and that the lattice volume almost constant with changing the e value. By Mohr salt analysis reveals the value of nonstoichiometric ratio y are found to be in the- wide range of 0.00~0.15. Using Mo¨ssbauer effect, the oxidation state and the magnetic hyperfine field of the iron nuclei in the samples have been studied. The value of the isomer shift is equal to that expected for trivalent and tetravalent iron ion. Electrical conductivity measurements show an decreasing the activation energy when the amount of tetravalent iron ion is increased
Gender difference of carotid artery by aging in healthy Korean subjects using novel software
( Yo-han Park ),( Yong-kyun Kim ),( Duck Jun Seo ),( Hyun-woong Park ),( Ki Hong Kim ),( Jang Ho Bae ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Carotid arterial intima and media thickness (IT and MT) between both genders by aging is not known, although carotid intima-media thickness (IMT) is known to be increased by aging and male gender shows thicker than female. Methods & Results: The CCA images (n=2,204 from 12 hospitals) were prospectively collected and sent to KRISS for core laboratory analysis using newly developed Korean software which can measure IT and MT. Men (n=1146, 52%) had more hypertension (65.7% vs. 53%), diabetes (46.7% vs. 38.7%), smoking (40.4% vs. 2.8%) and higher triglyceride (149.6±131.2 mg/dL vs. 121.5±91.9 mg/dL) and lower HDL cholesterol (47.1±12.0 mg/dL vs. 54.0±13.8 mg/dL) than women. Men had thicker CCA IT (0.31±0.07 mm vs. 0.30±0.06 mm, p=0.009) but both CCA IMT and CCA MT were not different between two groups (0.70±0.16 mm vs. 0.69±0.17 mm, p=0.180; 0.39±0.12 mm vs. 0.39±0.13 mm, p=0.694). Even though CCA IMT, IT and MT were increased with age but gender difference of carotid wall thickness was not evenly presented in the different age groups. This gender difference of CCA IT was not observed in the different age groups. And men had only thicker CCA IMT and MT in the age group less than 45 years old (0.58±0.09 vs. 0.54±0.09, p=0.004; 0.30±0.08 vs. 0.27±0.07, p=0.002). Conclusions: There was no significant gender difference between both genders in this study population. CCA IMT, IT and MT were similarly increased with age. The increased CIMT mainly reflect the increased CMT rather than CIT in asymptomatic healthy subjects.
( Yo Han Lee ),( Jae Young Jang ),( Woong Cheul Lee ),( Soung Won Jeong ),( Eui Ju Park ),( Byoung Moo Lee ),( Jin Nyoung Kim ),( Sae Hwan Lee ),( Sang Gyune Kim ),( Sang Woo Cha ),( Young Seok Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: We assessed baseline and on-treatment variables to determine predictive factors of the complete virologic response in naive chronic hepatitis B patients with entecavir therapy. Methods: A total of 261 naive chronic hepatitis B (CHB) patients treated with entecavir (0.5 mg daily) for at least 12 weeks were enrolled. The complete virologic response was defi ned as the absence of serum HBV-DNA by PCR assay (<20 IU/ml) on 2 consecutive measurement at 48week. Compliance with therapy was assessed whenpatients visit the outpatient clinic and phone calls. The medication adherence was more than 80% of all patients.Results: Finally, 98 patients were treated with entecavir for 96 weeks. And 151 patients were treated with entecavir for 48weeks. The mean follow-up duration was 20 ± 16.5 months. The complete virologic response at 48weeks was 67.5%. The cumulative rates of the virologic response at 12, 24, 48, and 96 weeks were 17.2%, 46.0%, 67.6%, and 71.4%, respectively. An absence of HBeAg and high DNA level at baseline were signifi cant predictors of the complete virologic response at 48 weeks in a univariate analysis (p<0.001, p=0.02). An absence of HBeAg at baseline was signifi cant predictor of the complete virologic response at 48weeks in a multivariate analysis (p<0.001). Also aminotransferase level was signifi cant predictor of the complete virologic response at 48 weeks in HBeAg positive patients (p<0.05). Conclusions: Our data showed a good complete virologic response (67.5%) in naiveCHB patients with entecavir therapy. Additionally, the predictor of the complete virologic response was an absence of HBeAg. Also, aminotransferase level can be used for predictor of the complete virologic response in HBeAg positive patients.
단순 흉부 둔상시 늑골촬영에서 미발견된 늑골골절의 진단: 초음파검사의 유용성
김요한 ( Yo Han Kim ),황은구 ( Eun Gu Hwang ),이송암 ( Song Am Lee ),이진웅 ( Jin Woong Lee ),이창희 ( Chang Hee Lee ),최영칠 ( Young Chil Choi ) 대한외상학회 2004 大韓外傷學會誌 Vol.17 No.1
Background: Rib fractures are the most common injuries resulting from blunt chest trauma. The sensitivity of conventional radiogrphy in showing the rib fracture is limited especially in whom involving the cartilage part of the rib. We investigated the rib fractures, those overlooked on conventional radiography, with the use of ultrasonography in minor blunt chest trauma. Materials and Methods: From september 2002 to March 2004, 40 patients (21 women and 29 men, mean age 43.3±15.1,range 16~85 years), with minor blunt chest trauma showing no evidence of rib fractures on conventional radiography, were admitted for examination with ultrasonography. Logistic regression analysis was done to outlined the clinical predictors of these incidious rib fractures. Results: A total of 15 (35%) patients showed rib lesions, whereas 25 (65%) patients had no evidence of rib lesions. Fractures of rib associated with a periosteal hematoma was the most common finding in ten (66.7%) patients followed by the rib fracture of the rib alone in four (26.7%) patients and subperiosteal hematoma alone in one (6.6%) patient. A total of eight (53.3%) patients had bony rib fractures, whereas seven (46.7%) patients had chondral rib fractures. Age (p=0.280), gender (p=0.431), type of etiology (p=0.823), duration of pain (p=0.470) and site of trauma (p=0.923) did not appear as significant predictors for these rib fractures. However, involved part of the rib showed a significant correlation with either age (p=0.043) or duration of pain (p=0.036). Bony rib fractures significantly occurred in elderly patients, and the duration of pain in patients with bony rib fractures was significantly longer than that of the patients with chondral rib fractures. Conclusions: Ultrasonography is a useful imaging method in showing the rib fractures those overlooked on conventional radiography in minor blunt chest trauma, and no significant clinical feature exists as a predictor for these insidious fractures. However, bony rib fractures significantly occur in elderly patients and result in a longer duration or pain.
자동차 정비 작업이 근골격계질환과 스트레스에 미치는 영향
길여진 ( Yo-chin Kil ),송영웅 ( Young-woong Song ) 대구가톨릭대학교 자연과학연구소 2023 자연과학연구논문집 Vol.21 No.1
This study tried to survey the prevalence of musculoskeletal disorders(MSD) and psychosocial stress among the automobile maintenance workers, and assessed the correlation between MSD symptoms and psychosocial stress. A structured self-reported questionnaire was distributed to 117 auto mechanics from wheel mobile equipment located in Daegu city and Gyeongsangbuk-do. The questionnaire was composed of three parts: (1) demographic and work related characteristics (age, martial status, smoking, physical load level ets.) (2) MSD symptoms (3) psychosocial stress. Psychosocial stress was measured using a PWI-SF(Psychosocial Well-being Index-Short Form). The prevalence of musculoskeletal disorders during last year preceding data collection was reported as about 31.4%. Marital status, exercise, phsical workload, job satisfaction, psychological stress were significantly associated with MSDs. Single, no exercise, high physical workload, low job satisfaction, high psychosocial stress showed high percentage of MSD symptoms. Of the 117 subjects, 8(8.2%) were in the normal group of psychosocial stress, 87(88.8%) were in the latent stress group of psychosocial stress and 3(3.1%) were in high risk stress group of psychosocial stress. Job satisfaction, MSD symptoms were found to be significantly associated with psychsocial stress. No exercise, high psychosocial stress were found to be significantly associated with possibility of MSD symptoms.
김요한 ( Yo Han Kim ),이송암 ( Song Am Lee ),황은구 ( Eun Gu Hwang ),이진웅 ( Jin Woong Lee ) 대한외상학회 2004 大韓外傷學會誌 Vol.17 No.2
Background: Sternal fracture may be associated with myocardial contusion even in patients without associated with significant injuries. The aims of this study are to determine the role of echocardiogram(ECHO) in treatment of sternal fracture and to suggest the indication of ECHO. Material and Method: We reviewed the records of 50 consecutive patients presenting with sternal fracture after blunt chest trauma. The relationships between ECHO, creatine kinase MB isoenzyme(CK-MB), electrocardiogram(EKG) were assessed in reference to myocardial contusion. Results: Twelve patients(24%) had one or more abnormal cardiac tests but only 4(8%) had clinically symptomatic myocardial contusion. Eight(22.9%) out of 35 ECHO studies revealed pericardial effusion which was not associated with the severity of all other associated injuries. The incidence of an abnormal ECHO finding in patients of isolated sternal fracture was similar to that of the patients who suffered multiple injuries. In 4 patients with pericardial effusion, this finding was not associated with any other abnormal tests and was regarded as of no clinical cardiac significance. On the other hand, a myocardial contusion was shown by ECHO study only while EKG and CK-MB tests remained normal in that patients. Conclusion: We suggest that the ECHO should be used as a diagnostic and triage tool in every patient with sternal fracture associated with other injuries. However patients with benign epicardial effusion can be discharged as soon as their clinical condition improves regardless of other associate injuries.