Electronic structure and optical properties of V-doped Bi₄Ti₃O₁₂ nanoparticles

Gu, Daguo,Qin, Yingying,Wen, Yongchun,Li, Tie,Qin, Lin,Seo, Hyo Jin Elsevier 2017 Journal of Alloys and Compounds Vol.695 No.-

<P><B>Abstract</B></P> <P>Pure and V<SUP>5+</SUP>-doped Bi<SUB>4</SUB>Ti<SUB>3</SUB>O<SUB>12</SUB> (BTO) photocatalysts were prepared by sol–gel routine and subsequent hydrothermal synthesis. The samples were developed into the platelike microparticles with the exposed (001) facets. The crystalline phases were verified via the XRD measurement. The surface characteristics of the photocatalysts were studied by TEM, SEM, BET, EDX and XPS measurements. The UV–vis optical absorption spectra showed that the V-doped photocatalysts exhibit an obvious red shift in the visible light absorption band compared with the pure BTO. Rhodamine B (RhB) dye solution was used as the model organic pollutants to verify the influence of V-doping on the photocatalytic activity. The 10 mol % V-doped BTO showed efficient photocatalytic ability. The photocatalytic activities and mechanisms were discussed on the crystal structure characteristics and the measurements such as EES and XPS results.</P> <P><B>Highlights</B></P> <P> <UL> <LI> V-doped Bi<SUB>4</SUB>Ti<SUB>3</SUB>O<SUB>12</SUB> has been synthesized by sol-gel hydrothermal process. </LI> <LI> Single-crystal micro-plates with exposed {001} facets are reached. </LI> <LI> Visible light absorption in Bi<SUB>4</SUB>Ti<SUB>3</SUB>O<SUB>12</SUB> can be greatly improved by V-doping. </LI> <LI> V-doped Bi<SUB>4</SUB>Ti<SUB>3</SUB>O<SUB>12</SUB> gives better visible light photoactivity. </LI> </UL> </P>

Progress of Solid Waste Management Policy in China

( Yingying Li ),( Jinhui Li ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 ISSE 초록집 Vol.2019 No.-

In order to further promote the prevention and control of environmental pollution by solid waste in China, the Ministry of Ecological and Environment released the revised draft of “the Law of the People's Republic of China on the Prevention and Control of Environmental Pollution by Solid Waste” for Comments in July 2018, and expected to be finished in 2019. The Ministry of Ecological Environment in March, 2018, reviewed and approved the “Implementation Plan for the Reform of Solid Waste Import Management System by Prohibiting the Entry of Foreign Waste”. In addition, in order to further standardize the import management of solid waste and prevent the environmental pollution of imported waste, the Ministry of Ecology and Environment has made four adjustments to the “Catalogue of Imported Waste Management”, which has greatly increased the categories of wastes prohibited from import.

Point defects and grain boundary effects on tensile strength of 3C-SiC studied by molecular dynamics simulations

Yingying Li,Yan Li,Wei Xiao 한국원자력학회 2019 Nuclear Engineering and Technology Vol.51 No.3

The tensile strength of irradiated 3C-SiC, SiC with artificial point defects, SiC with symmetric tilt grainboundaries (GBs), irradiated SiC with GBs are investigated using molecular dynamics simulations at300 K. For an irradiated SiC sample, the tensile strength decreases with the increase of irradiation dose. The Young's modulus decreases with the increase of irradiation dose which agrees well with experimentand simulation data. For artificial point defects, the designed point defects dramatically decrease thetensile strength of SiC at low concentration. Among the point defects studied in this work, the vacanciesdrop the strength the most seriously. SiC symmetric tilt GBs decrease the tensile strength of pure SiC. Under irradiated condition, the tensile strengths of all SiC samples with grain boundaries decrease andconverge to certain value because the structures become amorphous and the grain boundaries disappearafter high dose irradiation.

MoJMJD6, a Nuclear Protein, Regulates Conidial Germination and Appressorium Formation at the Early Stage of Pathogenesis in Magnaporthe oryzae

Li Zhang,Dong Li,Min Lu,Zechi Wu,Chaotian Liu,Yingying Shi,Mengyu Zhang,Zhangjie Nan,Weixiang Wang 한국식물병리학회 2023 Plant Pathology Journal Vol.39 No.4

In plant-pathogen interactions, Magnaporthe oryzae causes blast disease on more than 50 species of 14 monocot plants, including important crops such as rice, millet, and most 15 recently wheat. M. oryzae is a model fungus for studying plant-microbe interaction, and the main source for fungal pathogenesis in the field. Here we report that MoJMJD6 is required for conidium germination and appressorium formation in M. oryzae. We obtained MoJMJD6 mutants (ΔMojmjd6) using a target gene replacement strategy. The MoJMD6 deletion mutants were delayed for conidium germination, glycogen, and lipid droplets utilization and consequently had decreased virulence. In the ΔMojmjd6 null mutants, global histone methyltransferase modifications (H3K- 4me3, H3K9me3, H3K27me3, and H3K36me2/3) of the genome were unaffected. Taken together, our results indicated that MoJMJD6 function as a nuclear protein which plays an important role in conidium germination and appressorium formation in the M. oryzae. Our work provides insights into MoJMJD6-mediated regulation in the early stage of pathogenesis in plant fungi.

Exterior egg quality as affected by enrichment resources layout in furnished laying-hen cages

Li, Xiang,Chen, Donghua,Meng, Fanyu,Su, Yingying,Wang, Lisha,Zhang, Runxiang,Li, Jianhong,Bao, Jun Asian Australasian Association of Animal Productio 2017 Animal Bioscience Vol.30 No.10

Objective: This study aimed to investigate the effects of enrichment resources (a perch, dustbath, and nest) layout in furnished laying-hen cages (FC) on exterior quality of eggs. Methods: One hundred and sixty-eight (168) Hy-Line Brown laying hens at 16 weeks of age were randomly distributed to four treatments: small furnished cages (SFC), medium furnished cages type I (MFC-I), medium furnished cages type II (MFC-II), and medium furnished cages type III (MFC-III). Each treatment had 4 replicates or cages with 6 hens for SFC (24 birds for each SFC) and 12 hen/cage for MFC-I, -II, and -III (48 birds for each MFC-I, -II and -III). Following a 2-week acclimation, data collection started at 18 weeks of age and continued till 52 weeks of age. Dirtiness of egg surface or cracked shell as indicators of the exterior egg quality were recorded each week. Results: The results showed that the proportion of cracked or dirty eggs was significantly affected by the FC type (p<0.01) in that the highest proportion of cracked or dirty eggs was found in MFC-I and the lowest proportion of dirty eggs in SFC. The results of this showed that furnished cage types affected both dirty eggs and cracked eggs (p<0.01). The results also indicated that not nest but dustbath lead to more dirty eggs. Only MFC-I had higher dirty eggs at nest than other FC (p<0.01). The results of dirty eggs in MFC-I and MFC-II compared with SFC and MFC-III seemed suggest that a low position of dustbath led to more dirty eggs. Conclusion: SFC design affected exterior egg quality and the low position of dustbath in FC resulted in higher proportion of dirty eggs.

Oxalate formation during hydrogen peroxide-reinforced oxygen delignification

Yingying Liu,Shujuan Ge,Youming Li,Bingyun Li,Hailong Li 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.58 No.-

The effects of different process parameters (alkali dosage, hydrogen peroxide dosage, temperature, reaction time, and oxygen pressure) on oxalate formation during hydrogen peroxide-reinforced oxygen delignification (OP) of Eucalyptus kraft pulp were investigated in the present study. The relationships between oxalate formation and the dosages of both alkali and peroxide were found to be almost linear. Oxalate formation could be divided into “fast” and “slow” periods, depending on the reaction time. The best selectivity for the OP process was achieved using an alkali dosage of 2.0%, a hydrogen peroxide dosage of 2.0%, a temperature of 100 °C, an oxygen pressure of 0.6 MPa and a reaction time of 60 min. Oxalate formation was also, to some extent, reduced under these conditions. These results will be very helpful in optimizing the OP process, controlling oxalate formation and improving product quality.

Cellulose nanofibrils composite hydrogel with polydopamine@zeolitic imidazolate framework-8 encapsulated in used as efficient vehicles for controlled drug release

Yingying Liu,Ying Huo,Qing Fan,Mei-Ling Liu,Hongbin Liu,Bin Li,Youming Li 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.102 No.-

Herein, we report a nanocellulose hydrogel that has a packaging structure for on-demand drug release. Zeolitic imidazolate frameworks-8 (ZIF-8) were grown on the surface of polydopamine (PDA) to producePDA@ZIF-8 nanoparticles. The obtained PDA@ZIF-8 nanoparticles were then incorporated into a networkof cellulose nanofibrils (CNFs) to fabricate a PDA@ZIF-8/CNFs composite hydrogel. The loading ratio of thedrug tetracycline hydrochloride (TH) was 58%. A slight burst release behavior was observed at the beginning,and the composite hydrogel presented a significant pH-dependent release behavior. The drug deliverytime of the PDA@ZIF-8/CNFs composite hydrogel was 3.5 times longer than that of the PDA/CNFscomposite hydrogel. Furthermore, NIR light radiation accelerated the drug delivery rate. The drug releasemechanism was mainly driven by anomalous transport. Importantly, the novel PDA@ZIF-8/CNFs compositehydrogel was found to be biocompatible according to in vitro cytotoxicity test. Because of its uniquemultiple drug release responses, the PDA@ZIF-8/CNFs composite hydrogel may be used in future clinicalapplications as a promising drug delivery carrier.

Updated Bayesian Network Meta-Analysis of Adjuvant Targeted Treatment Regimens for Early Human Epidermal Growth Factor Receptor-2 Positive Breast Cancer

Xinyan Li,Litong Yao,Mozhi Wang,Mengshen Wang,Xiang Li,Xueting Yu,Jingyi Guo,Haoran Dong,Xiangyu Sun,Yingying Xu 한국유방암학회 2020 Journal of breast cancer Vol.23 No.4

Purpose: Combining targeted agents with adjuvant chemotherapy prolongs survival in human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients, but also increases the risk of adverse effects. The updated results of 3 randomized controlled trials (RCTs) were reported in 2019. Given the lack of adequate head-to-head pairwise assessment for anti-HER2 agents, network meta-analysis facilitates obtaining more precise inference for evidence-based therapy. Methods: RCTs comparing at least 2 anti-HER2 regimens in an adjuvant setting for HER2- positive early-stage breast cancer (EBC) were included. Hazard ratios for overall survival (OS) and disease free survival (DFS), with respective 95% confidence intervals were pooled for assessment of efficacy. A Bayesian statistical model was used, and odds ratios (ORs) for adverse events (AEs) were used to pool effect sizes. Results: We demonstrated that 1-year trastuzumab plus chemotherapy had increased efficacy compared to shorter or longer treatment duration. The OR of cardiac events gradually increased from 6 months to 1 and 2-year trastuzumab arms, relative to chemotherapy only. Compared to trastuzumab plus chemotherapy, dual HER2-targeting therapies increased DFS, especially for hormone receptor negative patients. Dual anti-HER2 blockade regimens revealed an increased probability of gastrointestinal reactions. As a second agent, pertuzumab showed significantly higher DFS and OS. Conclusion: We conclude that 1-year adjuvant trastuzumab should remain as the standard treatment for HER2-positive EBC patients, as it has greater efficacy and a manageable proportion of AEs. Clinical efficacy can be increased for hormone receptor-negative tumors by including a second HER2-targeted agent to the treatment regimen. For hormone receptor-positive cases with basal disease, it is acceptable to reduce the risk of cardiotoxicity by shortening the duration of trastuzumab.

Neutrophil-inspired photothermo-responsive drug delivery system for targeted treatment of bacterial infection and endotoxins neutralization

Chengnan Li,Yingying Gan,Zongshao Li,Mengjing Fu,Yuzhen Li,Xinran Peng,Yongqiang Yang,Guo‑bao Tian,Yi Yan Yang,Peiyan Yuan,Xin Ding 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background P. aeruginosa, a highly virulent Gram-negative bacterium, can cause severe nosocomial infections, and it has developed resistance against most antibiotics. New therapeutic strategies are urgently needed to treat such bacterial infection and reduce its toxicity caused by endotoxin (lipopolysaccharide, LPS). Neutrophils have been proven to be able to target inflammation site and neutrophil membrane receptors such as Toll-like receptor-4 (TLR4) and CD14, and exhibit specific affinity to LPS. However, antibacterial delivery system based on the unique properties of neutrophils has not been reported. Methods A neutrophil-inspired antibacterial delivery system for targeted photothermal treatment, stimuli-responsive antibiotic release and endotoxin neutralization is reported in this study. Specifically, the photothermal reagent indocyanine green (ICG) and antibiotic rifampicin (RIF) are co-loaded into poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP-ICG/RIF), followed by coating with neutrophil membrane to obtain antibacterial delivery system (NM-NP-ICG/RIF). The inflammation targeting properties, synergistic antibacterial activity of photothermal therapy and antibiotic treatment, and endotoxin neutralization have been studied in vitro. A P. aeruginosa-induced murine skin abscess infection model has been used to evaluate the therapeutic efficacy of the NM-NP-ICG/RIF. Results Once irradiated by near-infrared lasers, the heat generated by NP-ICG/RIF triggers the release of RIF and ICG, resulting in a synergistic chemo-photothermal antibacterial effect against P. aeruginosa (~ 99.99% killing efficiency in 5 min). After coating with neutrophil-like cell membrane vesicles (NMVs), the nanoparticles (NM-NP-ICG/RIF) specifically bind to inflammatory vascular endothelial cells in infectious site, endowing the nanoparticles with an infection microenvironment targeting function to enhance retention time. Importantly, it is discovered for the first time that NMVs-coated nanoparticles are able to neutralize endotoxins. The P. aeruginosa murine skin abscess infection model further demonstrates the in vivo therapeutic efficacy of NM-NP-ICG/RIF. Conclusion The neutrophil-inspired antibacterial delivery system (NM-NP-ICG/RIF) is capable of targeting infection microenvironment, neutralizing endotoxin, and eradicating bacteria through a synergistic effect of photothermal therapy and antibiotic treatment. This drug delivery system made from FDA-approved compounds provides a promising approach to fighting against hard-to-treat bacterial infections.

The Progress of Implementation of Basel Convention in China

( Jinhui Li ),( Yingying Li ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 ISSE 초록집 Vol.2019 No.-

As one of the earliest parties and signatories, China has been actively implementing the Basel Convention in order to promote its full implementation in China. First of all, China has established management mechanism of solid waste import and export, and made efforts to promote cooperation among various ministries, actively carry out waste import and export supervision and combat illegal transboundary movement. Secondly, a complete system of laws and regulations on the control of transboundary movement and environmental management of hazardous wastes and other wastes has been established, such as Law of the People's Republic of China on the Prevention and Control of Solid Waste Pollution and Law on Promoting Circular Economy. In addition, China has initially formed a management and technical support system of hazardous waste and other waste by establishing Basel Convention Regional Centre, and the solid waste management centers at all levels. Meanwhile, China's solid waste and hazardous waste treatment industry has been established and gradually expanded.