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Turkish bath tradition: The example of Gaziantep, Turkey
Tülay Karadayı Yenice,Meltem Ararat 국립민속박물관 2022 International Journal of Intangible Heritage Vol.17 No.-
Conservation of monumental and civil architectural heritage is an important element of cultural sustainability. Preserving these structures with their original characters and transferring them to future generations contributes to social memory formation and builds a bridge between the past and future generations. However, a sustainable and holistic conservation approach should cover not only tangible but also intangible heritage. Considering the tangible and intangible cultural heritage as a whole is also important to transfer the architectural heritage to future generations accurately. Local culture, customs and traditions also affect and change the formation of local architecture. Therefore, this research aims to examine the influence of local bath traditions on bath structures. The research specifically focuses on the relationship between local hammam traditions and Turkish bath architecture in the city of Gaziantep, Turkey. To do this, first, Gaziantep bath culture is examined in detail and its unique character is identified. Then, field research was carried out to investigate historical bath structures on-site and to conduct spatial analyses. The findings of the research show that intangible cultural heritage is a significant factor in shaping tangible heritage. It is believed that the research will contribute to considering tangible and intangible cultural heritage with a holistic comprehension of conservation in the example of historical Gaziantep hammams.
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Lycopene Protects Against Spontaneous Ovarian Cancer Formation in Laying Hens
Kazim Sahin,Engin Yenice,Mehmet Tuzcu,Cemal Orhan,Cengizhan Mizrak,Ibrahim H. Ozercan,Nurhan Sahin,Bahiddin Yilmaz,Birdal Bilir,Bulent Ozpolat,Omer Kucuk 대한암예방학회 2018 Journal of cancer prevention Vol.23 No.1
Background: Dietary intake of lycopene has been associated with a reduced risk of ovarian cancer, suggesting its chemopreventive potential against ovarian carcinogenesis. Lycopene’s molecular mechanisms of action in ovarian cancer have not been fully understood. Therefore, in the present study, we investigated the effects of lycopene on the ovarian cancer formation using the laying hen model, a biologically relevant animal model of spontaneous ovarian carcinogenesis due to high incidence rates similar to humans. Methods: In this study, a total of 150 laying hens at age of 102 weeks were randomized into groups of 50: a control group (0 mg of lycopene per kg of diet) and two treatment groups (200 mg or 400 mg of lycopene per kg of diet, or ~26 and 52 mg/d/hen, respectively). At the end of 12 months, blood, ovarian tissues and tumors were collected. Results: We observed that lycopene supplementation significantly reduced the overall ovarian tumor incidence (P < 0.01) as well as the number and the size of the tumors (P < 0.004 and P < 0.005, respectively). Lycopene also significantly decreased the rate of adenocarcinoma, including serous and mucinous subtypes (P < 0.006). Moreover, we also found that the serum level of oxidative stress marker malondialdehyde was significantly lower in lycopene-fed hens compared to control birds (P < 0.001). Molecular analysis of the ovarian tumors revealed that lycopene reduced the expression of NF-B while increasing the expression of nuclear factor erythroid 2 and its major target protein, heme oxygenase 1. In addition, lycopene supplementation decreased the expression of STAT3 by inducing the protein inhibitor of activated STAT3 expression in the ovarian tissues. Conclusions: Taken together, our findings strongly support the potential of lycopene in the chemoprevention of ovarian cancer through antioxidant and anti-inflammatory mechanisms. (J Cancer Prev 2018;23:25-36)
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Earthquake performance investigation of R/C residential buildings in Turkey
Kasim Armagan Korkmaz,Fuat Demir,Tugce Yenice 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.15 No.6
The aim of this study is to determine the earthquake performances of reinforced concrete (R/C) residential buildings in Turkey and to analyze the parameters that affect the performance. The performance of Turkish residential buildings, determined by their levels of damage, directly relates to their structural systems. Damage parameters observed from previous earthquakes define structural parameters selected to be used in the present study. Five different types of frame R/C buildings were modeled. For the analysis, the model buildings vary according to the number of stories, column sizes, and reinforcement and concrete strength parameters. The analyses consider gravity forces and earthquake loads through 1975 and 2007 Turkish design codes. In a total of 720 different R/C buildings were investigated for the analysis to obtain capacity curves. A performance evaluation was employed by considering the Turkish design code (TDC-2007). The current study ignores irregularities such as soft stories or short columns. The study’s analysis considers a comparison of the parameters’ influence on the structural performance of the model buildings.
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Vitamin D Levels in Patients with Breast Cancer: Importance of Dressing Style
Alco, Gul,Igdem, Sefik,Dincer, Maktav,Ozmen, Vahit,Saglam, Sezer,Selamoglu, Derya,Erdogan, Zeynep,Ordu, Cetin,Pilanci, Kezban Nur,Bozdogan, Atilla,Yenice, Sedef,Tecimer, Coskun,Demir, Gokhan,Koksal, G Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3
Background: Vitamin D deficiency is a potentially modifiable risk factor that may be targeted for breast cancer (BC) prevention. It may also be related to prognosis after diagnosis and treatment. The aim of our study was to determine the prevalence of vitamin D deficiency as measured by serum 25-hydroxy vitamin D (25-OHD) levels in patients with BC and to evaluate its correlations with life-style and treatments. Materials and Methods: This study included 186 patients with stage 0-III BC treated in our breast center between 2010-2013. The correlation between serum baseline 25-OHD levels and supplement usage, age, menopausal status, diabetes mellitus, usage of bisphosphonates, body-mass index (BMI), season, dressing style, administration of systemic treatments and radiotherapy were investigated. The distribution of serum 25-OHD levels was categorized as deficient (<10ng/ml), insufficient (10-24 ng/ml), and sufficient (25-80 ng/ml). Results: The median age of the patients was 51 years (range: 27-79 years) and 70% of them had deficient/insufficient 25-OHD levels. On univariate analysis, vitamin D deficiency/insufficiency was more common in patients with none or low dose vitamin D supplementation at the baseline, high BMI (${\geq}25$), no bisphosphonate usage, and a conservative dressing style. On multivariate analysis, none or low dose vitamin D supplementation, and decreased sun-exposure due to a conservative dressing style were found as independent factors increasing risk of vitamin D deficiency/insufficiency 28.7 (p=0.002) and 13.4 (p=0.003) fold, respectively. Conclusions: The prevalence of serum 25-OHD deficiency/insufficiency is high in our BC survivors. Vitamin D status should be routinely evaluated for all women, especially those with a conservative dressing style, as part of regular preventive care, and they should take supplemental vitamin D.
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