야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin

Kim, Jong Gwang,Sohn, Sang Kyun,Chae, Yee Soo,Song, Hong Suk,Kwon, Ki-Young,Do, Young Rok,Kim, Min Kyoung,Lee, Kyung Hee,Hyun, Myung Soo,Lee, Won Sik,Sohn, Chang-Hak,Jung, Joo Seop,Kim, Gab Chul,Chung Springer-Verlag 2009 Cancer chemotherapy and pharmacology Vol.64 No.2

Establishment of Plant Regeneration System Via Somatic Embryogenesis and Shoot Organogenesis from Leaf, Petiole and Stem Explants of Gynura Procumbens

Suk Weon Kim(김석원),Nornita Sham(노니타),Eun Yee Jie(지은이),Myung Suk Ahn(안명숙),Seung A Choi(최승아),Ye In Jeon(전예인) 한국원예학회 2016 한국원예학회 학술발표요지 Vol.2016 No.10

Clinical Characteristics and Treatment Outcomes of Pulmonary Diseases Caused by Coinfections With Multiple Nontuberculous Mycobacterial Species

Kim Sol,Woo A La,Yong Seung Hyun,Leem Ah Young,Lee Su Hwan,Lee Sang Hoon,Kim Song Yee,Chung Kyungsoo,Kim Eun Young,Jung Ji Ye,Kang Young Ae,Park Moo Suk,Kim Young Sam,Park Youngmok 대한의학회 2024 Journal of Korean medical science Vol.39 No.20

Background: Coinfections with multiple nontuberculous mycobacterial (NTM) species have not been widely studied. We aimed to evaluate the clinical characteristics and treatment outcomes in patients with NTM-pulmonary disease (PD) caused by coinfection with multiple NTM species. Methods: We retrospectively reviewed patients with NTM-PD at a tertiary referral hospital in Korea between March 2012 and December 2018. Coinfection was defined as two or more species of NTM pathogens isolated from the same respiratory specimen or different specimens within three months. Results: Among 1,009 patients with NTM-PD, 147 (14.6%) NTM coinfections were observed (average age 64.7 years, 69.4% women). NTM species were identified more frequently (median 6 vs. 3 times, P < 0.001) in the coinfection group than in the single species group, and follow-up duration was also longer in the coinfection group (median 44.9 vs. 27.1 months, P < 0.001). Mycobacterium avium complex (MAC) and M. abscessus and M. massiliense (MAB) were the dominant combinations (n = 71, 48.3%). For patients treated for over six months in the MAC plus MAB group (n = 31), sputum culture conversion and microbiological cure were achieved in 67.7% and 41.9% of patients, respectively. We divided the MAC plus MAB coinfection group into three subgroups according to the target mycobacteria; however, no statistical differences were found in the treatment outcomes. Conclusion: In NTM-PD cases, a significant number of multiple NTM species coinfections occurred. Proper identification of all cultured NTM species through follow-up is necessary to detect multispecies coinfections. Further research is needed to understand the nature of NTM-PD in such cases.

Resonance effects in thickness-dependent ultrafast carrier and phonon dynamics of topological insulator Bi₂Se₃

Kim, Sung,Shin, Dong Hee,Kim, Ju Hwan,Jang, Chan Wook,Park, Jun Woo,Lee, Hosun,Choi, Suk-Ho,Kim, Seung Hyun,Yee, Ki-Ju,Bansal, Namrata,Oh, Seongshik IOP 2016 Nanotechnology Vol.27 No.4

<P>Resonance effects in the thickness-dependent ultrafast carrier and phonon dynamics of topological insulator Bi<SUB>2</SUB>Se<SUB>3</SUB> are found irrespective of the kind of substrate by measuring thickness-dependent abrupt changes of pump-probe differential-reflectivity signals (Δ<I>R</I>/<I>R</I>) from Bi<SUB>2</SUB>Se<SUB>3</SUB> thin films on four different substrates of poly- and single-crystalline (sc-) ZnO, sc-GaN and SiO<SUB>2</SUB>. The absolute peak intensity of the Δ<I>R</I>/<I>R</I> is maximized at ∼<I>t</I> <SUB>C</SUB> (6 ∼ 9 quintuple layers), which is not directly related to but is very close to the critical thickness below which the energy gap opens. The intensities of the two phonon modes deduced from the oscillatory behaviors superimposed on the Δ<I>R</I>/<I>R</I> profiles are also peaked at ∼<I>t</I> <SUB>C</SUB> for the four kinds of substrates, consistent with the thickness-dependent Raman-scattering behaviors. These resonant effects and others are discussed based on possible physical mechanisms including the effects of three-dimensional carrier depletion and intersurface coupling.</P>

The Comparison of Compression Hip Screw and Bipolar Hemiarthroplasty for the Treatment of AO Type A2 Intertrochanteric Fractures

( Yee Suk Kim ),( Jae Seung Hur ),( Kyu Tae Hwang ),( Il Yong Choi ),( Young Ho Kim ) 대한고관절학회 2014 Hip and Pelvis Vol.26 No.2

Purpose: The purpose of this study was to compare the outcomes of osteosynthesis using compression hip screw fixation versus bipolar hemiarthroplasty in AO type A2 intertrochanteric fractures. Materials and Methods: From March 2003 to December 2009, 89 patients were included in this study. They were treated using compression hip screws (43 cases) or bipolar hemiarthroplasty (46 cases). The mean age of patients was 77.7 years (65-94 years) and the mean follow-up period was 5.9 years (1-8.3 years). For comparison of the outcomes in the two groups, statistical analyses were performed with parameters including anesthesia time, operation time, amount of transfusion, hospital stay, general complications, clinical outcome, time of partial weight-bearing using a walker, and radiological failure rate. Results: Differences in the amount of transfusion, general complications, and clinical outcome (Merle d’Aubigne´ and Postel score) were not statistically significant between the two groups. The bipolar hemiarthroplasty group showed better results than the compression hip screw group for anesthesia time and the time of partial weight-bearing using a walker. Radiological failures were observed in hips in one case (2.2%) of bipolar hemiarthroplasty, and in four cases (9.3%) of compression hip screw fixation. Conclusion: Among elderly individuals with AO type A2 intertrochanteric fractures, patients treated with bipolar hemiarthroplasty were able to perform early ambulation. However, no significant difference in operation time, amount of postoperative transfusion, clinical results, hospital stay, and radiological failure rate was observed between the bipolar hemiarthroplasty and compression hip screw fixation groups.

The trends and risk factors to predict adverse outcomes in gestational diabetes mellitus: a 10-year experience from 2006 to 2015 in a single tertiary center

( Minji Kim ),( Juyoung Park ),( Soo Hyun Kim ),( Yoo Min Kim ),( Cheonga Yee ),( Suk-joo Choi ),( Soo-young Oh ),( Cheong-rae Roh ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.3

Objective To investigate the change of maternal characteristics, delivery and neonatal outcomes in gestational diabetes mellitus (GDM) over recent 10 years and to identify the risk factors associated with adverse outcome. Methods Consecutive GDM patients (n=947) delivered in our institution were included. Research period was arbitrarily divided into 2 periods (period 1: from 2006 to 2010, period 2: from 2011 to 2015). Multiple pregnancies or preexisting diabetes were excluded. Maternal baseline characteristics, delivery and neonatal outcomes were reviewed. Fetal biometric findings by prenatal ultrasonography were collected. Adverse pregnancy outcome (APO) was defined by the presence of one of the followings; shoulder dystocia, neonatal macrosomia (>4 kg), neonatal hypoglycemia (<35 mg/dL), respiratory distress syndrome (RDS), and admission to the neonatal intensive care unit (NICU) in term pregnancy. Results Period 2 was associated with older maternal age (34 vs. 33, P<0.001) and higher proportion of GDM A2 compared to period 1 (30.9% vs. 23.0%, P=0.009). By univariate analysis, APO was associated with increased body mass index (BMI) at pre-pregnancy (23.4 kg/㎡ vs. 21.8 kg/㎡, P=0.001) or delivery (27.9 kg/㎡ vs. 25.8 kg/㎡, P<0.001), higher HbA1c at diagnosis (5.6% vs. 5.3%, P<0.001) or delivery (5.8% vs. 5.5%, P=0.044), and larger fetal biometric findings (abdominal circumference [AC] and estimated fetal weight, P=0.029 and P=0.007, respectively). Multivariate analysis showed pre-pregnancy BMI (odds ratio [OR], 1.101; 90% confidence interval [CI], 1.028-1.180) and fetal AC (OR, 1.218; 90% CI, 1.012-1.466) were independently associated with adverse outcomes. Conclusion Our study demonstrated the trends and relevant factors associated with the adverse outcomes.

Wagner 재치환 대퇴스템을 이용한 인공 고관절 재치환술

김이석 ( Yee Suk Kim ),조창민 ( Chang Min Cho ),황규태 ( Kyu Tae Hwang ),김영호 ( Young Ho Kim ),최일용 ( Il Yong Choi ) 대한고관절학회 2010 Hip and Pelvis Vol.22 No.2

Purpose: We evaluated the results of revision total hip arthroplasty using a Wagner revision femoral stem. Materials and Methods: We enrolled 54 patients who underwent hip arthroplasty using a Wagner revision stem between 1996 and 2004. The mean age at revision surgery was 65.4 years and the mean follow up period was 7.2 years. There were 42 aseptic loosenings and 12 periprosthetic fractures. The pre-operative femoral defects were classified according to the Paprosky classification system. Clinical and radiological results were evaluated. Results: The mean Harris hip score improved from 43 preoperatively to 89 at the latest follow up. There were 2 cases with inguinal pain and 1 with thigh pain; in each case pain was reduced by medications. All cases showed endosteal bone formation around the stem. Five cases showed radiolucency in Gruen zones 1 and 7. Six cases had hips that showed subsidence (average=3.1 mm). There was 1 dislocation (1.8%) and 1 intraoperative periprosthetic fracture (1.8%). There were no re-revisions. Conclusion: Use of a Wagner revision femoral stem for revision total hip arthroplasty elicits satisfactory results including stable fixation of the stem, a low rate of subsidence, and a low rate of dislocation.

Serum CA 19-9 Level Correlates CT Severity Score in Patients with NTM-PD

( Kangjoon Kim ),( Hye-jeong Lee ),( Seung Hyun Yong ),( Su Hwan Lee ),( Sang Hoon Lee ),( Song Yee Kim ),( Kyungsoo Chung ),( Eun Young Kim ),( Ji Ye Jung ),( Moo Suk Park ),( Young Sam Kim ),( Joon 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-

Background Until now, there is no validated clinical biomarker of nontuberculous mycobacterial pulmonary disease (NTM-PD) in terms of evaluating disease severity or treatment response. Limited data suggests that elevated serum carbohydrate antigen 19-9 (CA 19-9) is observed in the patients with NTM-PD, and the level decreases following the successful NTM-PD treatment. Methods This retrospective study examined 79 NTM-PD patients who conducted both measurement of serum CA 19-9 level and chest computed tomography (CT) scan, less than a month apart. The NTM-PD disease severity were rated by the scoring system based on CT images. Correlation between the CT score and the serum level of CA 19-9 were evaluated by using Spearman’s correlation coefficient and Spearman’s partial correlation coefficient, and the latter was controlled for the variables of age, sex and body mass index (BMI). Results Serum CA 19-9 levels had a positive correlation with the CT score, especially for the score of total (rs=.416, p<0.01), and the sub-score of bronchiectasis (rs=.251, p<0.05), bronchiolitis (rs=.289, p<0.01), cavity (rs=.221, p<0.05), and consolidation (rs=.303, p<0.01). Patients’ BMI had a negative correlation with the CT score (rs=-.358, p<0.01), but had no significant correlation with serum CA 19-9 level itself. After controlling for the variables of age, sex and BMI, partial correlation analysis showed statistically significant positive correlation between serum CA 19-9 level and the CT score of bronchiectasis, bronchiolitis, cavity, consolidation, and total sum (Table 1). Conclusion Serum CA 19-9 levels had a positive correlation with the CT severity score of NTM-PD. Serum CA 19-9 may be a useful biological marker for evaluating disease activity or therapeutic response in the patients with NTM-PD, and further study is warranted.

Hydroxyapatite 피복된 ABG I 삽입물을 이용한 무시멘트 인공 고관절 전치환술: 최소 10년 이상 추시 결과

김이석 ( Yee Suk Kim ),박동혁 ( Dong Hyuck Park ),황규태 ( Kyu Tae Hwang ),김영호 ( Young Ho Kim ),최일용 ( Il Yong Choi ) 대한고관절학회 2013 Hip and Pelvis Vol.25 No.3

Purpose: The purpose of this study was to evaluate the outcomes of total hip arthroplasty (THA) with an ABG I hip prosthesis after a minimum ten-year follow up. Materials and Methods: From January 1996 to March 2001, 121 hips in 104 patients, whi were followed up for a minimum of ten-years, were enrolled in this study. The clinical and radiographic outcomes were evaluated and Kaplan-Meier survival analysis was performed. Results: The mean Harris hip score at the last follow-up was 84 points. A radiolucent line around the cup, osteolysis, and cup loosening were observed in 5 hips(4.1%), 53 hips(43.8%), and 5 hips(4.1%), respectively. In the femoral side, osteolysis and stem loosening were observed in 11 hips(9.1%) and 2 hips(1.7%), respectively. The mean linear wear rate of the polyethylene liner was 0.23 mm/yr. Forty four revisions(36.3%) were performed. The outcomes were similar regardless of the cause of primary THA. The survival rate with the end point of revision due to cup loosening was 56.3%, and revision due to stem loosening was 98.1% after a 16 year follow-up. Conclusion: High polyethylene wear and the disappointing survival rate of the ABGI cup were observed after a minimum ten year follow-up. Therefore, close observation of patients who have received an ABG I prosthesis is necessary.