고양이 위 평활근에서 KCI에 의한 근수축에 대한 Protein Kinase의 조절

심상수,김승록,심혜선,이덕주,한상준,윤신희,조양혁,김명석 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.3

고양이 위 평활근 수축에 대한 Vanadate와 Pervanadate의 효과

심상수,최효봉,심혜선,이덕주,윤신희,한상준,김명석,조양혁 大韓消化器病學會 1999 大韓消化器病學會誌 Vol.33 No.1

Cholinergic Control of Pancreatic Secretion: The Effects of Atropine on Plasma Cholecystokinin and Secretin Release

Jo. Yang-Hyeok,Rhie. Duck-Joo,Chang. Young-Soon,Hahn. Sang-June,Sim. Sang-Soo,Kim. Myung-Suk,Kim. Chung-Chin 대한생리학회 1991 대한생리학회지 Vol.25 No.1

Generally, it has been known that cholecystokinin (CCK) release into the plasma is under cholinergic control, but secretin release is not. Thus in anesthetized dogs we studied the effect of atropine (50 μg/kg followed by 50 μg/kg/hr) on pancreatic secretion and plasma concentrations of bioactive CCK and immunoreactive secretin in response to intraduodenal perfusion of sodium oleate (1, 3 and 9 mmol/hr). The volume, protein output and bicarbonate output of the secretion were increased by sodium cleats and this oleate-induced secretion was decreased significantly by atropine administration. However the increased plasma CCK and secretin levels by sodium oleate were not changed by atropine. These results indicate that atropine suppressed sodium oleate-induced pancreatic secretion through inhibiting cholinergic mechanism directly rather than decreasing the release of pancreatic secretory hormones. In another set of experiments, bilateral cervical vagi were stimulated electrically to observe the changes of pancreatic secretion and the above two plasma hormone levels in the presence or absence of atropine. In the vagally stimulated dogs, the volume, protein output and bicarbonate output of the pancreatic secretion were increased significantly. Both plasma secretin and CCK were concomitantly released significantly by vagal stimulation. Atropine significantly depressed the pancreatic secretory response as well as the release of these two pancreatic secretory hormones. Therefore, we conclude that in the presence of atropine the depressed pancreatic response to vagal stimulation is at least, in part, due to decreased release of endogenous CCK and secretin. In the vagally stimulated animals, however, the involvement of direct cholinergic influence on pancreatic exocrine gland remains to be answered.

적출한 고양이 위(胃) 근절편에서 서파의 전파 및 발생빈도에 미치는 Dopamine의 영향

조양혁(Jo, Yang-Hyeok),심상수(Sim, Sang-Soo),김명석(Kim, Myung-Suk),김정진(Kim, Chung-Chin),최현(Choi, Hyun) 대한생리학회 1986 대한생리학회지 Vol.20 No.1

The effect of dopamine on the propagation and the frequency electrical activities (slow wave) of the stomach was studied in isolated stomach muscle strips of 145 cats, The gastric slow wave monopolarly recorded by four capillary electrodes (Ag-AgCl) in Krebs-Ringer solution (ph 7.4, temperature 36±0.5℃) bubbled with 5% CO₂ in O₂. Dopamine caused concentration-dependent changes of direction of slow wave propagation with decline in development of irregular propagation by domperidone pretreatment. Dopamine also increased the variation of slow wave frequency concentration-dependently. The variation of slow wave frequency induced by dopamine was significantly inhibited by pretreatment with domperidone and phentolamine but not with propranolol, hexamethonium and tetrodotoxin. It is therefore suggested that dopamine plays a role in the genesis of gastric electrical abnormality acting on dopamine receptors and partly on α-adrenergic receptors in cats. 위(胃) 전기활동(서파)의 전파(傳播) 및 발생빈도에 미치는 dopamine의 영향을 주명하기 위하여 145마리의 고양이를 사용하며 다음의 실험을 실시하였다. 위의 복측부분을 적출하여 종주근의 주행 방향으로 대만쪽에서 길이 5cm, 폭 1.2cm인 근절편을 만들어, 95% O₂와 5% CO₂가 계속 공급되는 Krebs-Ringer용액 (PH 7.4, 온도 36±0.5℃)내에 두고 가느다란 은선이 들어있는 모세관 전극 (Ag-AgCl)을 사음하여 단극성으로 서파를 기록하였다. dopamine의 첨가후 위서파의 전파방향은 첨가한 농도에 비례하여 전환이 많아졌으나, dopamine의 영향은 domperidone의 전처치로 유의하게 억제되었다. dopamine은 또한 농도가 증가함에 따라 불규칙한 위서파의 발생만도를 증가시켰으며 이 현상은 domperidone 및 Phentolamine에 의하여 억제되었으나 Propranolol, hexamethonium 및 tetrodotoxin에 의하여는 억제되지 않았다. 그러므로 dopamine은 고양이 위에서 dopamine receptor와 일부 α-adrenergic receptor에 작용하며 이상적(異常的)서파를 발생시킨다고 사료된다.

Fe₃O₄ nanoparticles encapsulated in one-dimensional Li₄Ti₅O₁₂ nanomatrix: An extremely reversible anode for long life and high capacity Li-ion batteries

Jo, Mi Ru,Jung, Jaepyeong,Lee, Gi-Hyeok,Kim, Yunok,Song, Kyeongse,Yang, Junghoon,Chae, Ji Su,Roh, Kwang Chul,Kim, Yong-Il,Yoon, Won-Sub,Kang, Yong-Mook Elsevier 2016 Nano energy Vol.19 No.-

<P><B>Abstract</B></P> <P>Transition metal oxides are very promising electrode materials for lithium-ion batteries that operate through conversion reactions. Energy densities for conversion reactions are higher than for intercalation reactions, but most of transition metal oxides show poor cycling performance and reversibility due to the pulverization of active materials and subsequent volume changes. We here report a facile and scalable synthesis for realizing Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB>-coated Fe/Fe<SUB>3</SUB>O<SUB>4</SUB> hybrid nanocomposites in the form of one-dimensional nanofibers (C@Fe-Fe<SUB>3</SUB>O<SUB>4</SUB>/Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB> hybrid NFs). This is a new class of highly-reversible and safe anode material that can significantly reduce the lithium-ion diffusion length and improve strain tolerance during Li ion insertion/extraction. Its oxidation state was also impressively controlled through a carbothermal reaction during annealing. The precise oxidation state control of C@Fe-Fe<SUB>3</SUB>O<SUB>4</SUB>/Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB> hybrid NFs simultaneously enabled high capacity due to the conversion reaction of Fe<SUB>3</SUB>O<SUB>4</SUB> as well as high reversibility and stability resulting from zero-strain characteristics and superb kinetics of Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB>. This new electrode material appears promising for not only future energy systems but also various electronic devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> C@Fe-Fe<SUB>3</SUB>O<SUB>4</SUB>/Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB> hybrid NFs showed extremely stable cyclic retention, which enabled to realize a full cell based on transition metal oxides anode for the first time. </LI> <LI> Its mechanical flexibility, electric conductivity and thermal stability were surprisingly enhanced. </LI> <LI> This enhancement was attributed to zero-strain feature of Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB>, and the evolution of Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12-δ</SUB> and metallic Fe. </LI> <LI> This novel hybrid composites showed a synergistic effect thanks to high capacity of Fe<SUB>3</SUB>O<SUB>4</SUB>, high thermal and structural stability of Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB>, and the improved kinetics from dexterous oxidation state and morphology control. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>An effective strategy to significantly boost the structural stability and electrochemical performance of Fe<SUB>3</SUB>O<SUB>4</SUB> nanoparticles through the embedment in Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB> nanomatrix was successfully demonstrated despite its extremely irreversible conversion reaction. The resultant C@Fe-Fe<SUB>3</SUB>O<SUB>4</SUB>/Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB> hybrid NFs showed excellent mechanical flexibility and electronic conductivity that could be each assigned to high stability or zero-strain feature of Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12</SUB>, and the evolution of oxygen-deficient Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12-δ</SUB> as well as metallic Fe</P> <P>[DISPLAY OMISSION]</P>

Adjusting the Anisotropy of 1D Sb₂ Se₃ Nanostructures for Highly Efficient Photoelectrochemical Water Splitting

Yang, Wooseok,Ahn, Jihoon,Oh, Yunjung,Tan, Jeiwan,Lee, Hyungsoo,Park, Jaemin,Kwon, Hyeok-Chan,Kim, Juran,Jo, William,Kim, Joosun,Moon, Jooho Wiley (John WileySons) 2018 ADVANCED ENERGY MATERIALS Vol.8 No.14

화물차사고 비율에 따른 고속도로 교통사고 분석모형에 대한 연구

Yang, Sung-Ryong,Yoon, Byoung-jo,Ko, Eun-Hyeok 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.4

고속도로에서 화물차는 승용차에 비해 도로의 많은 부분을 점유한다. 이로 인해 도로의 용량은 상대적으로 감소하며, 국소적으로 주변 운전자에게 위협적인 요소로 작용한다. 화물차 사고는 일반적인 사고와 달리 사고 특성이 다르므로 분석 방법 또한 일반적인 사고와 다르게 적용해야 한다. 사고 분석 방법 중 사고예측모형은 특정 구간에 대한 사고건수를 예측하며 교통계획을 수립할 때 사고 예방을 위한 대책 수립과 도로의 위험성을 진단할 때 활용된다. 이에 본 연구는 고속도로의 화물차 간 사고 비율을 적용하여 사고예측모형에 투입될 수 있는 보정계수를 산출하는 것을 목적으로 한다. 연구를 위해 고속도로를 대상으로 사고 자료를 수집하였으며 2014~2016년까지 3개 년도의 교통량 및 사고 자료를 활용하였다. 연간 사고건수를 토대로 사고예측모형을 개발하였으며, 본 연구를 통해 화물차 간 사고 비율에 따른 사고예측모형을 비교함으로써 실질적인 고속도로 사고예측모형을 확인하고 그에 대한 대책을 제시하고자 한다. Trucks take up more portions than cars on highways. Due to this, road use relatively diminish and it serves locally as a threatening factor to nearby drivers. Baggage car accident has distinct characteristics so that it needs the application of different analysis opposed to ordinary accidents. Accident prediction model, one of accident analyses, is used to predict the numbers of accident in certain parts, establish traffic plans as well as accident prevention methods, and diagnose the danger of roads. Thus, this study aims to apply the accident rate of baggage car on highways and calculate the correction factor to be put in the accident prediction models. Accident data based on highway was collected and traffic amounts and accident documents between 2014 and 2016 were utilized. The author developed an accident prediction model based on numbers of annual accidents and set mean annual and daily traffic amounts. This study intends to identify the practical accident prediction model on highway and present an appropriate solution by comparing the prediction model in accords with the accident rate between baggage cars.

경도관 동맥색전술을 이용한 비정상 자궁출혈의 치료

양승부,최교창,이상진,정영진,임한혁,한효상,황인철,조환성 순천향의학연구소 2005 Journal of Soonchunhyang Medical Science Vol.11 No.1

Objective : Our purpose of this study is to evaluate the effectiveness of the transcatheter arterial embolization for the management of abnormal uterine bleeding. Materials and Methods : 14 patients with massive or recurrent uterine bleeding underwent percutaneous transcatheter arterial embolization between February 2003 and September 2004. We reviewed 14 cases of uterine artery or internal iliac artery embolization using gelfoam or PVA particles. Results : Good management of uterine bleeding was achieved in 13 of 14(93%) cases. The cause of abnormal uterine bleeding was myoma(5 case), post D & E bleeding(3), acquired vascular malformation(3), pseudoaneurysm(1), adenomyosis(1), and endometrial hyperplasia(1). Conclusion : Transcatheter artery embolization is an effective and life-saving procedure in massive or recurrent uterine bleeding. Early diagnosis and prompt transcatheter arterial embolization is a useful mangement of uterine bleeding.

Effect of continuous exposure to low-dose-rate gamma irradiation on cell growth and lipid accumulation of marine microalgae

Jeong, Dong Hyeok,Jeong, Min Ho,Jeong, Soo Kyung,Yang, Kwangmo,Jo, Wol Soon CHAPMAN & HALL 2017 AQUACULTURE INTERNATIONAL Vol.25 No.2

화물차사고 비율에 따른 고속도로 교통사고 분석모형에 대한 연구

Sung-Ryong Yang,Byoung-jo Yoon,Eun-Hyeok Ko 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.4

고속도로에서 화물차는 승용차에 비해 도로의 많은 부분을 점유한다. 이로 인해 도로의 용량은 상대적으로 감소하며, 국소적으로 주변 운전자에게 위협적인 요소로 작용한다. 화물차 사고는 일반적인 사고와 달리 사고 특성이 다르므로 분석 방법 또한 일반적인 사고와 다르게 적용해야 한다. 사고 분석 방법 중 사고예측모형은 특정 구간에 대한 사고건수를 예측하며 교통계획을 수립할 때 사고 예방을 위한 대책 수립과 도로의 위험성을 진단할 때 활용된다. 이에 본 연구는 고속도로의 화물차 간 사고 비율을 적용하여 사고예측모형에 투입될 수 있는 보정계수를 산출하는 것을 목적으로 한다. 연구를 위해 고속도로를 대상으로 사고 자료를 수집하였으며 2014~2016년까지 3개 년도의 교통량 및 사고 자료를 활용하였다. 연간 사고건수를 토대로 사고예측모형을 개발하였으며, 본 연구를 통해 화물차 간 사고 비율에 따른 사고예측모형을 비교함으로써 실질적인 고속도로 사고예측모형을 확인하고 그에 대한 대책을 제시하고자 한다. Trucks take up more portions than cars on highways. Due to this, road use relatively diminish and it serves locally as a threatening factor to nearby drivers. Baggage car accident has distinct characteristics so that it needs the application of different analysis opposed to ordinary accidents. Accident prediction model, one of accident analyses, is used to predict the numbers of accident in certain parts, establish traffic plans as well as accident prevention methods, and diagnose the danger of roads. Thus, this study aims to apply the accident rate of baggage car on highways and calculate the correction factor to be put in the accident prediction models. Accident data based on highway was collected and traffic amounts and accident documents between 2014 and 2016 were utilized. The author developed an accident prediction model based on numbers of annual accidents and set mean annual and daily traffic amounts. This study intends to identify the practical accident prediction model on highway and present an appropriate solution by comparing the prediction model in accords with the accident rate between baggage cars.