하악골 전돌자의 악교정 수술을 동반한 교정치료 전후 하악골 주위조직의 변화에 관한 연구

양병호,차경석 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.2

심한 골격성 전후방 및 수직적 악골 부조화를 동반하는 경우는 교정치료 만으로는 만족할 만한 결과를 얻기 어렵고 많은 전후방적인 이동과 치료의 안정성을 얻기 위하여 교정치료와 동반한 악교정수술이 필요하다. 하악전돌증 환자에서의 치료의 목적은 저작,발음 등 악구강계의 기능을 개선하고 안모의 심미성을 증진시키는 한편 안정성을 유지하는 데에 있다. 악교정수술에 의한 하악골의 이동으로 위치의 변화를 보이는 조직으로는 설골, 인두, 혀 등이 있다. 악교정수술을 동반한 교정치료를 받은 골격성 하악전돌증 환자에서 주위 조직들에서 변화 양상을 관찰하고 악교정수술 전후와 보정기간 후의 회귀나 재발에 의한 설골, 인두, 혀 및 상하순의 변화를 살펴보기 위하여 본 연구를 시행하였다. 본 연구에서는 하악전돌증을 주소로 내원하여 하악상행지 시상골절단술을 동반한 교정치료를 받은 환자 22명의 측모두부방사선 규격사진을 수술 전 (T1), 수술 후 (T2), 교정장치의 제거 2년 보정 후 (T3) 3회에 걸쳐 계측 및 비교한 후 다음과 같은 결과를 얻었다. 1.수술 후 설골이 상악골 및 교합평면에 대해 시계방향으로 회전하였으며 보정기간 후 회귀함을 보여주었다. 2.하악골의 수술에 의한 후방이동 후 설골이 후하방으로 이동하였으며 보정기간 후 상전 방으로 회귀함을 보여주었다. 3.인두의 깊이 변화는 상부에서 수술직후 약간 감소하는 경향을 보여 주었으나 보정 전후에 전반적으로 유의한 차이가 없는 것으로 나타났다. 4.혀의 기저부와 관련해서는 혀 기저부 각 (Cv4ia-hy-pt)이 감소하고, 혀의 기저부 배면이 후하방으로 변화하는 양상을 보여주었으며 보정기간 후에 상방으로 변화하였다. 5.상하순의 두께는 상순에서는 수술 후 감소하였다가 다시 증가하는 양상을, 하순이하의 연조직에서 두께가 증가하였다가 감소하는 형태로 나타났다. 이는 하순에서는 수술 후 잉여 연조직에 의한 두께의 증가가 나타나고 상순에서는 구륜근에 의한 장력에 의해 상순의 두께가 감소하였다가 보정 기간 후 새로운 악골 위치로 적응하는 것으로 생각된다. Severe skeletal anteroposterior and vertical discrepancy is difficult to obtain satisfactory result by only orthodontic treatment, and much anteroposterior movement and treatment stability require orthodontic treatment with orthognathic surgery. The treatment goal of mandibular prognathic patients is to promote the function of stomatognathic system including mastication and phonetics, to improve the esthetics of facial profile and to maintain stability. Positional changes of hyoid bone, pharynx and tongue were seen with mandibular movement after orthognathic surgery. This study was performed to observe the changes of perimandibular tissues of orthodontic patients with skeletal mandibular prognathism who treated with orthodontic treatment, and the changes of hyoid bone, pharynx and tongue by relapse or recurrance after before and after orthognathic surgery and retention. The 22 patients who had mandibular prognathism were selected. They treated with orthodontic treatment with sagittal split ramus osteotomy as orthognathic surgery. And lateral cephalometric radiographs were taken 3 times : pre-surgery (T1), immediate post-surgery (T2) and 2 years after retention (T3). The results were as follows : 1.The hyoid bone returned back after clockwise rotation to maxilla and occlusal plane during retention (p〈0.01). 2.The hyoid bone moved posterior-interiorly by mandibular surgery and returned back anterior-superior after retention. (p〈0.01) 3.The changes of pharyngeal depth showed a little decrease at upper area in post- surgery, but it was not a significant difference generally through before, after and retention. 4.In relating to tongue base, the angle of tongue base was decreased and the dorsal area of tongue base moved to inferior-posterior direction and to superior direction again after retention (p〈0.01). 5.Related to the thickness of upper and lower lip, the thickness of upper lip decreased after surgery, and the soft tissues below lower lip increased after surgery and decreased after retention.

복소함수 T_c(z)=z^n+c의 쥴리아 집합

양승갑,조경숙,조성훈 명지대학교 교육대학원 1998 敎育大學院 論叢 Vol.1 No.-

복소 함수의 쥴리아 집합이란 무한대로 발사하는 점들의 집합의 경계를 말한다. 이것은 쥴리아 집합의 어떤 점은 무한대로 발산하지 않는 궤도를 갖고 있으나, 이 궤도의 근방에서 무한대로 발산하는 궤도를 갖는 점이 존재함을 의미한다. 본 논문의 목적은 T_c(z)=z^n+c 형태의 복소 함수의 쥴리아 집합에 대한 연구에 있다. 이 때 z와 c는 복소수이고, n≥2이다. 특히, 매개 상수 c 에 대한 여러 가지 형태의 쥴리아 집합에 대하여 살펴보고, 또한 쥴리아 집합에 대한 주기성과 대칭성을 조사하였다.

ACL 손상환자의 보행형태 분석

이경일,박양현,김용숙 朝鮮大學校 스포츠科學硏究所 2004 스포츠科學硏究 Vol.15 No.-

By analyzing on walking patterns of patients who have damaged ACL, we intended to use this study as data for several walking researches. Followings are the result of angles and angular velocities that are variables in the study. 1. The angle of ankle showed flection of 91.28˚ and 93.54˚ at the point E2 (opposite toe off) and at the point of E3(opposite heel contact). The angle of normal left foot was flection of 96.66˚ and 92.30˚ when it was at the point of E1(heel strike) and E2(opposite toe off). 2. The angle of knee showed the biggest curve of 121.07˚ at the point of E2(opposite toe off ) and there was a significant difference with the angle of left knee. 3. The angle of hip joint was the biggest numerical value extension, 49.93˚ at the point of E1(heel strike ) and at the point of E3(opposite heel contact), it showed the curve of 38.43˚. We could see the significant difference at normal left hip joint but at the point of E3(opposite heel contact) the numerical value of the curve appeared to be 89.49˚. 4. The angular velocity of ankle was the biggest as 67.33 at the point of E1(heel strike) and simultaneously, the angular velocity of left ankle appeared to be the smallest as -19.80˚. 5. The angular velocity of knee was -78.28 at the point of E2 (opposite toe off) and at the same point, the velocity of normal left knee was 46.68˚ which was the biggest numerical value. 6. The angular velocity of hip joint were -7.18˚ and -58.03˚ at the point of E1(heel strike) and E2(opposite toe off). At the same point, the velocity of left hip joint showed bigger number of 27.45˚ and -6.11˚.

대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

2-Deoxy-D-Glucose에 의한 대사성 쇼크가 무우스의 면역 반응에 미치는 영향

김양숙,장선일,박래길,조성경,정헌택 최신의학사 1991 最新醫學 Vol.34 No.2

Carbonic Anhydrase Inhibitors가 Lipopolysaccharide에 의해 유도된 골흡수에 미치는 영향

박양호,차경석 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.1

To study bone resorption mechanism effect of LPS on the Ca release from fetal rat ulnae and radii, and effects of carbonic anhydrase inhibitors on the LPS-induced bone resorption in organ culture were studied. Ulnae and radii were removed from 19 days old fetal rats, prelabelled by subcutaneous injection of 200 Ci CaCl₂into their mother on the 17th day of gestation. Radioactivities of Ca released into media were determined after 24, 48 and 72 hours. Effects of LPS and carbonic anhydrase inhibitors were observed by the ratio of % release Ca between paired control and experimently group. The observed results were as follows : 1. LPS(1㎍/㎖) supplemented in media for 72hours increased the Ca release significantly after 48 and 72 hours of culture and LPS(10㎍/㎖) increased the Ca release significantly after 72 hours of culture. 2. LPS-induced Ca release was not inhibited significantly by 1mM sulfanilamide but inhibited significantly by 10mM significantly after 48 and 72 hours of culture. 3. LPS-induced Ca release was not inhibited significantly by 0.1mM dichlorphenamide but inhibited significantly by 10mM dichlorphenamide after 48 and 72 hours of culture. 4. LPS-induced Ca release was not inhibited significantly by 1mM acetazolamide but inhibited significantly by 5mM acetazolamide after 72 hours of culture.

치매노인의 인지능력에 미치는 꽃장식의 효과와 꽃의 선호도 조사

윤숙영,김홍열,--,우태양 한국화훼연구회 2002 화훼연구 Vol.10 No.1

본 연구는 대구광역시에 위치한 <햇빛치매어르신주간보호센터>에 있는 치매노인을 대상으로 꽃장식이 치매노인의 인지기능에 미치는 영향을 알아보고 꽃장식에서 꽃의 색과 크기의 선호도를 조사하기 위해서 치매노인 6명을 대상으로 2002년 2월 14일부터 2002년 5월 9일까지 주 1회씩 총 12회 원예치료 프로그램을 실시하였다. 대상자는 모두 여성이었다. 평가결과는 다음과 같다. MMSE-K 평가결과 대상자 A는 원예치료 실시 전 13점에서 실시 후 18점으로, 대상자 D는 원예치료 실시 전 5점에서 13점으로 유의하게 향상되는 것을 볼 수 있었다. 대상자 B는 7점에서 8점으로, 대상자 E는 3점에서 7점으로 향상되었으나 유의차가 없었다. 대상자 C는 원예치료 실시 전 15점에서 실시 후에는 14점으로 오히려 낮아졌으나 유의차는 없었다. 대상자 F는 인지능력이 없는 대상자로서 실시 전후 큰 변화가 없었다. 꽃의 선호도 조사결과 색은 적색과 황색 그리고 분홍색 순으로 선호하였고 크기는 중간형보다는 크거나 작지만 풍성한 꽃을 선호하였다. 이상의 결과로부터 꽃장식은 치매노인의 인지기능 향상에 효과적이었다. 재료는 매회 달랐지만 작품을 구사하여 다듬고, 자르고, 꽂고 하는 반복적인 활동을 통해 흥미를 유발하여 적극적으로 자신감을 갖게 되었으며, 또한 결과물을 가족들과 함께 공유하게 함으로써 가족관계도 개선되었다. Abstract. This study set out to research preference of flowers, to analyze the impacts of floral decoration on the improvement of recognition ability in the demented old adults in order to develop an more effective horticultural therapy program for the demented old adults. The subjects were made out of the demented old adults who were taken care of at <HABIT Demented Old Adults Day Care Center> located in Icheon-dong, Nam-gu, Daegu Metropolitan City. Total six subjects were included in experiment. They were all female, and their average age was 76. The experiment was conducted once a week from February 14 to May 9, 2002, total in 12 times. The experiment was only focused on floral decorations. The color and size of flowers were considered to decide the subjects preference. The subjects preferred red and yellow flowers. They also liked big flowers or small but opulent ones. As for floral decoration, the material flowers were different each session. But the subjects were aroused into interest via repetitive activities such as designing their works and arranging, cutting, and putting in flowers. Their active and confident attitudes became evident, and their relationships with their family grew better as they shared their works with them.

세침 흡입 생검으로 진단된 간의 혈관근지방종 1 예

이경아,유은실,민영일,김해련,심기남,정훈용,양석균,홍원선,박의련,이문규 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6

Hepatic angiomyolipoma is a rare benign tumor of the liver composed of blood vessel, smooth muscle cells, fat and myelocomponent. The preoperative diagnosed of the lesion is important because of its therapeutic implications. Radiologic findings are not specific because the composed elements are variable in proportion and distribution. Thus, the findings at computed tomography, ultrasono graphy and magnetic resonance imaging may be only suggestive and its definitive diagnosed requires histologic confirmation. We experienced a case of hepatic angiomyolipoma in patient with chronic hepatitis diagnosed preoperatively by fine-needle aspiraton biopsy under ultrasound guidance. To our knowledge, this is the first case of hepatic angiomyolipoma diagnosed preoperatively in Korea. We report it with review of literatures.

Carbonic Anhydrase Inhibitors가 Lipopolysaccharide에 의해 유도된 골흡수에 미치는 영향

朴亮鎬,車敬石,金世源 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

To study bone resorption mechanism, effect of LPS on the ^45Ca release from fetal rat ulnae and radii, and effects of carbonic anhydrase inhibitors on the LPS-induced bone resorption in organ culture were studied. Ulnae and radii were removed from 19 day old fatal rats, prelabelled by subcutaneous injection of 200μCi ^45CaCl_2 into their mother on the 17th day of gestation. Radioactivities of ^45Ca released into media were determined after 24, 48 and 72 hours. Effects of LPS and carbonic anhydrase inhibitors were observed by the ratio of % release of ^45Ca between paired control and experimental group. The observed results were as follows : 1. LPS(1㎍/ml) supplemented in media for 72hours increased the ^45Ca release significantly after 48 and 72 hours of culture and LPS(10㎍/ml) increased the ^45Ca release significantly after 72 hours of culture. 2. LPS-induced ^45Ca release was not inhibited significantly by 1mM sulfanilamide but inhibited significantly by 10mM sulfanilamide after 48 and 72 hours of culture. 3. LPS-induced ^45Ca release was not inhibited significantly by 0.1mM dichlorphenamide but inhibited significantly by 1mM dichlorphenamide after 48 and 72 hours of culture. 4. LPS-induced ^45Ca release was not inhibited significantly by 1mM acetazolamide but inhibited significantly by 5mM acetazolamide after 72 hours of culture.

독시사이클린 나노입자가 함유된 치주용 키토산 스트럽의 제조 및 특성

송경숙,양재헌,김영일,정규호 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.4

Local drug delivery by using biocompatible polymers has been developed in the treatment of periodontitis for many years. In the field of dental therapy, doxycycline is usually a first choice because of its broad-spectrum antibiotic activity. The strip releases antibiotics for a week, and the polymer should be degradable after a week. In this study, we prepared and evaluated the chitosan strips and nanoparticle strips containing doxycycline hydrochloride, and studied their antiacterial activity, dissoultion, and degrability in vitro. The weight of cast strip containing a 5 mg of doxycycline hydrochloride and a 45 mg of chitosan polymer was 57.67±0.17 mg. The release rate of doxycycline hydrochloride from the strip was measured by HPLC. The drug released from chitosan strip and nanoparticle strip was shown to be 50 ㎍/ml, in first 24 hours. In antibacterial test showed growth inhibitory activity after 24 hrs anaerobic incubation. In vitro degradability showed demolished weight of 93.74±0.08% chitosan strip, 82.48±1.29% chitosan nanoparticle strip, 2.47±1.99% polycarprolactione strip (control). These results showed that, with this doxycycline hydrochloride strip, it is feasible to obtain a sustained release of the drug within the periodontal pocket for seven days which may be improve for local drug delivery system for treatment of periodontal disease.