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      • Analytical study of the failure mode and pullout capacity of suction anchors in sand

        Liu, Haixiao,Peng, Jinsong,Zhao, Yanbing Techno-Press 2015 Ocean systems engineering Vol.5 No.4

        Suction anchors are widely adopted and play an important role in mooring systems. However, how to reliably predict the failure mode and ultimate pullout capacity of the anchor in sand, especially by an easy-to-use theoretical method, is still a great challenge. Existing methods for predicting the inclined pullout capacity of suction anchors in sand are mainly based on experiments or finite element analysis. In the present work, based on a rational mechanical model for suction anchors and the failure mechanism of the anchor in the seabed, an analytical model is developed which can predict the failure mode and ultimate pullout capacity of suction anchors in sand under inclined loading. Detailed parametric analysis is performed to explore the effects of different parameters on the failure mode and ultimate pullout capacity of the anchor. To examine the present model, the results from experiments and finite element analysis are employed to compare with the theoretical predictions, and a general agreement is obtained. An analytical method that can evaluate the optimal position of the attachment point is also proposed in the present study. The present work demonstrates that the failure mode and pullout capacity of suction anchors in sand can be easily and reasonably predicted by the theoretical model, which might be a useful supplement to the experimental and numerical methods in analyzing the behavior of suction anchors.

      • SCIESCOPUSKCI등재

        Production of Recombinant Human Papillomavirus Type 52 L1 Protein in Hansenula polymorpha Formed Virus-Like Particles

        Liu, Cunbao,Yao, Yufeng,Yang, Xu,Bai, Hongmei,Huang, Weiwei,Xia, Ye,Ma, Yanbing The Korean Society for Microbiology and Biotechnol 2015 Journal of microbiology and biotechnology Vol.25 No.6

        Human papillomavirus (HPV) type 52 is a high-risk HPV responsible for cervical cancer. HPV type 52 is common around the world and is the most common in some Asian regions. The available prophylactic HPV vaccines protect only from HPV types 16 and 18. Supplementing economical vaccines that target HPV type 52 may satisfactorily complement available prophylactic vaccines. A codon-adapted HPV 52 L1 gene was expressed in the methylotrophic yeast Hansenula polymorpha, which is used as an industrial platform for economical hepatitis B surface antigen particle production in China. We found that the recombinant proteins produced in this expression system could form virus-like particles (VLPs) with diameters of approximately 50 nm. This study suggests that the HPV 52 VLPs produced in this platform may satisfactorily complement available prophylactic vaccines in fighting against HPVs prevalent in Asia.

      • Analytical study of the failure mode and pullout capacity of suction anchors in clay

        Liu, Haixiao,Wang, Chen,Zhao, Yanbing Techno-Press 2013 Ocean systems engineering Vol.3 No.2

        Suction anchors are widely adopted in mooring systems. However there are still challenges in predicting the failure mode and ultimate pullout capacity of the anchor. Previously published methods for predicting the inclined pullout capacity of suction anchors are mainly based on experimental data or the FEM analysis. In the present work, an analytical method that is capable of predicting the failure mode and ultimate pullout capacity of the suction anchor in clay under inclined loading is developed. This method is based on a rational mechanical model for suction anchors and the knowledge of the mechanism that the anchor fails in seabed soils. In order to examine the analytical model, the failure angle and pullout capacity of suction anchors from FEM simulation, numerical solution and laboratory tests in uniform and linear cohesive soils are employed to compare with the theoretical predictions and the agreement is satisfactory. An analytical method that can evaluate the optimal position of the attachment point is also proposed in the present study. The present work proves that the failure mode and pullout capacity of suction anchors can be reasonably determined by the developed analytical method.

      • KCI등재

        Clustering memory-guided anomaly detection model for large-scale screening of esophageal endoscopic images

        Wu Yanbing,Zhao Zijian,Pang Xuejiao,Liu Jin 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.4

        A deep learning screening model of esophageal endoscopic images can reduce the burden on endoscopists. However, most deep learning methods require many labeled data with balanced categories, and their ability to deal with new diseases not appearing in the training set is limited. This study elaborated a semi-supervised anomaly detection model for the initial screening of esophageal endoscopic images, requiring a single class of samples as a training set. The reconstruction-based method was used for anomaly detection. The model’s framework was a variational auto-encoder, with two memory modules added in latent space to restrain its generalization ability. In the memory module, a clustering operation was introduced to provide a better distribution of memory vectors, promoting their compactness with encoded features and separation from each other. A detailed description and theoretical substantiation of the proposed model were presented. A dataset containing 7989 esophageal endoscopic images labeled by experienced endoscopists was used for numerical experiments. The proposed model results were compared with those of other auto-encoder-based anomaly detection methods, outperforming them and achieving an area under the curve of 0.8212. The ablation study was also conducted to validate the effectiveness of each model’s part, and new data were successfully incorporated to assess the model feasibility and applicability range.

      • Research on a New Hybrid Intelligent Fault Diagnosis Method and its Application

        Zhenhua Wang,Zhentao Liu,Xueyan Lan,Jian Liu,Shaowei Wang,Yangming Wu,Yanbing Xue 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.7

        In order to overcome the shortcomings of slow convergence speed and easy falling into the local minimum values of the BP neural network, an improved particle swarm optimization(PSO) algorithm is proposed to optimize the redial basic function (RBF) neural network, in order to propose a new hybrid intelligent fault diagnosis(IMPSO-RBFNN) method. In the IMPSO-RBFNN method, the adaptive dynamic adjusting strategy is used to control the inertia weight of the PSO algorithm in order to an improved particle swarm optimization(IMPSO) algorithm. Then the IMPSO algorithm is selected to optimize the parameters of RBF neural network by encoding the particle and continuous iteration of the IMPSO algorithm in order to obtain the optimal combination values of the parameters of RBF neural network. The optimal combination values are regarded as the values of these parameters of the RBFNN for constructing the final IMPSO-RBFNN method. In order to test the effectiveness of the proposed IMPSO-RBFNN method, the data from bearing data center of CWRU is selected in this paper. The experiment results show that the IMPSO algorithm can effectively optimize the weights of RBFNN, the IMPSO-RBFNN method can accurately realize high precision fault diagnosis of rolling bearing.

      • SCOPUSKCI등재

        Determination of Herbicide Propisochlor in Soil, Water and Rice by Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) Method Using by UPLC-ESI-MS/MS

        Wu, Xiaohu,Xu, Jun,Liu, Xingang,Dong, Fengshou,Wu, Yanbing,Zhang, Ying,Zheng, Yongquan Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.3

        A simple, quick and reliable analytical method for the confirmation and quantification of propisochlor was developed. The propisochlor was extracted from water, soil and rice (stalks, rice and hull) matrices using acetonitrile, and cleaned up with primary secondary amine and determined by UPLC-MS/MS. The LODs of propisochlor ranged from 0.03 ${\mu}g/kg$ to 0.12 ${\mu}g/kg$, while the LOQs ranged from 0.1 ${\mu}g/kg$ to 0.4 ${\mu}g/kg$ in different matrixes. The mean recoveries of propisochlor at three levels (0.005, 0.01 and 0.05 mg/kg) were in the range of 73.7-94.9% with intra-day relative standard deviations (RSD) of 1.1-13.9% and inter-day $RSD_R$ of 3.3-12.7%. This method is suitable for routine analysis of propisochlor under field conditions. The half-lives of propisochlor in rice stalks, water and soil were 1.7, 1.5 and 2.3 days in Hunan, 5.7, 1.0 and 1.9 days in Anhui and 4.8, 1.0 and 3.1 days in Guangxi.

      • KCI등재

        A fancy hydrangea shape bimetallic Ni-Mo oxide of remarkable catalytic effect for hydrogen storage of MgH2

        Jiaqi Zhang,Quanhui Hou,Yanbing Liu,Xinglin Yang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.118 No.-

        The design of catalysts with excellent catalytic activity plays an important role in the field of solid-statehydrogen storage of new energy sources. Herein, a novel hydrangea-like NiO@NiMoO4 composite catalystwas prepared through a facile hydrothermal reaction. Subsequently, NiO@NiMoO4 was doped into MgH2by ball milling to solve the problems of high dehydrogenation temperature and slow desorption kineticsof MgH2. It can be seen from the experimental results that the MgH2 + 10 wt% NiO@NiMoO4 compositestarts to dehydrogenate at about 190 C, which is about 170 C lower than that of pure MgH2. Meanwhile,after complete dehydrogenation, the composites can start to absorb hydrogen below 40 C. Comparedwith pure MgH2, the activation energy of hydrogen absorption and dehydrogenation of the compositedecreased by 47.6 kJ/mol and 46.5 kJ/mol, respectively. In 10th cycle tests, the MgH2 + 10 wt%NiO@NiMoO4 composite still has good cycle stability. After adding a small amount of biomass charcoal,the hydrogen storage capacity can even be maintained above 97%. Furthermore, the characterizationresults show that the in situ generated new species Mo and Mg2Ni/Mg2NiH4 synergistically promotethe adsorption and dissociation of hydrogen. This new synergistic mechanism provides new comprehensiveinsights for improving reversible hydrogen storage in MgH2.

      • KCI등재

        Internal Mammary Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy in Breast Cancer

        Zhao Bi,Peng Chen,Jingjing Liu,Yanbing Liu,Pengfei Qiu,Qifeng Yang,Weizhen Zheng,Yongsheng Wang 한국유방암학회 2018 Journal of breast cancer Vol.21 No.4

        Purpose: The definition of nodal pathologic complete response (pCR) after a neoadjuvant chemotherapy (NAC) just included the evaluation of axillary lymph node (ALN) without internal mammary lymph node. This study aimed to evaluate the feasibility of internal mammary-sentinel lymph node biopsy (IM-SLNB) in patients with breast cancer who underwent NAC. Methods: From November 2011 to 2017, 179 patients with primary breast cancer who underwent operation after NAC were included in this study. All patients received radiotracer injection with modified injection technology. IM-SLNB would be performed on patients with internal mammary sentinel lymph node (IMSLN) visualization. Results: Among the 158 patients with cN+ disease, the rate of nodal pCR was 36.1% (57/158). Among the 179 patients, the visualization rate of IMSLN was 31.8% (57/179) and was 12.3% (7/57) and 87.7% (50/57) among those with cN0 and cN+ disease, respectively. Furthermore, the detection rate of IMSLN was 31.3% (56/179). The success rate of IM-SLNB was 98.2% (56/57). The IMSLN metastasis rate was 7.1% (4/56), and all of them were accompanied by ALN metastasis. The number of positive ALNs in patients with IMSLN metastasis was 3, 6, 8, and 9. The pathology nodal stage had been changed from pN1/ pN2 to pN3b. The pathology stage had been changed from IIA/ IIIA to IIIC. Conclusion: Patients with visualization of IMSLN should perform IM-SLNB after NAC, especially for patients with cN+ disease, in order to complete lymph nodal staging. IM-SLNB could further improve the definition of nodal pCR and guide the internal mammary node irradiation.

      • KCI등재

        Determination of Herbicide Propisochlor in Soil, Water and Rice by Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) Method Using by UPLC-ESI-MS/MS

        Xiaohu Wu,Jun Xu,Xingang Liu,Feng Shou Dong,Yanbing Wu,Ying Zhang,Yongquan Zheng 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.3

        A simple, quick and reliable analytical method for the confirmation and quantification of propisochlor was developed. The propisochlor was extracted from water, soil and rice (stalks, rice and hull) matrices using acetonitrile, and cleaned up with primary secondary amine and determined by UPLC-MS/MS. The LODs of propisochlor ranged from 0.03 μg/kg to 0.12 μg/kg, while the LOQs ranged from 0.1 μg/kg to 0.4 μg/kg in different matrixes. The mean recoveries of propisochlor at three levels (0.005, 0.01 and 0.05 mg/kg) were in the range of 73.7-94.9% with intra-day relative standard deviations (RSD) of 1.1-13.9% and inter-day RSDR of 3.3-12.7%. This method is suitable for routine analysis of propisochlor under field conditions. The half-lives of propisochlor in rice stalks, water and soil were 1.7, 1.5 and 2.3 days in Hunan, 5.7, 1.0 and 1.9 days in Anhui and 4.8, 1.0 and 3.1 days in Guangxi.

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