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        • Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis

          Yu, K,H.,Hong, K,S.,Lee, B‐,C.,Oh, M‐,S.,Cho, Y,J.,Koo, J‐,S.,Park, J‐,M.,Bae, H‐,J.,Han, M‐,K.,Ju, Y,S.,Kang, D‐,W.,Appelros, P. Blackwell Publishing Ltd 2011 Acta neurologica Scandinavica Vol.123 No.5

          <P>Yu K‐H, Hong K‐S, Lee B‐C, Oh M‐S, Cho Y‐J, Koo J‐S, Park J‐M, Bae H‐J, Han M‐K, Ju Y‐S, Kang D‐W, Appelros P, Norrving B, Terent A. Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis. 
Acta Neurol Scand: 2011: 123: 325–331. 
© 2010 John Wiley & Sons A/S.</P><P><B>Background – </B> It has not been clarified whether the disparity in ischemic stroke outcome between populations is caused by ethnic and geographic differences or by variations in case mix. Propensity score matching (PSM) analysis can overcome some analytical problems but is rarely used in stroke outcome research. This study was to compare the ischemic stroke case‐fatality between two PSM cohorts of Sweden and Korea.</P><P><B>Methods – </B> Prognostic variables related to baseline characteristics and stroke care were included in our PSM model. Then, we selected 7675 Swedish and 1220 Korean patients with ischemic stroke from each stroke registers and performed one‐to‐one matching based on propensity scores of each patient.</P><P><B>Results – </B> After PSM, all measured variables were well balanced in 1163 matched subjects, and the 90‐day case‐fatality was identical 6.2% (HR 0.997, 95%CI 0.905–1.099) in Sweden and Korea.</P><P><B>Conclusions – </B> No difference is found in the 90‐day case‐fatality in propensity score‐matched Swedish and Korean patients with ischemic stroke.</P>

        • KCI우수등재

          열처리에 따른 Y₂O₃박막의 미세 구조 변화와 전기적 특성 변화에 대한 고찰

          정윤하(Y. H. Jung),강성관(S. K. Kang),김은하(E. H. Kim),고대홍(D. H. Ko),조만호(M. H. Cho),황정남(C. N. Whang) 한국진공학회(ASCT) 1999 Applied Science and Convergence Technology Vol.8 No.3(1)

          p-type Si (100) 기판 위에 습식 산화법으로 SiO₂ 층을 형성한 후, Ionized Cluster Beam(ICB) 증착 방법으로 200 Å 두께의 Y₂O₃ 박막을 증착 하였다. Y₂O₃ 박막이 증착 된 시편을 산소, 아르곤 분위기에서 열처리한 후, Atomic Force Microscopy(AFM)과 Transmission Electron Microscopy(TEM)을 사용하여 Y₂O₃ 박막의 표면과 계면을 관찰하였다. 열처리를 수행한 후 Y₂O₃ 박막과 Si 기판 사이에서 SiO₂층이 성장하고, 이트륨실리 케이트 층이 형성되는 것을 관찰할 수 있었다. 산소 분위기에서 열처리를 수행한 시편의 Y₂O₃ 박막 표면을 관찰한 결과, 표면 상부에 아르곤 분위기에서 열처리한 시편에서는 보이지 않았던 새로운 상이 형성되었음을 알 수 있었다. 또한 전기적 특성을 측정하기 위하여 Al/Y₂O₃/p-type Si (100) 의 캐패시턴스-전압 특성을 관찰하였고, 그 결과 Y₂O₃ 박막의 유전 상수 값이 약 9정도임을 알 수 있었다. We investigated the interfacial reactions between the Y₂O₃ film deposited by ICB processing and p-type (100) Si substrates upon annealing treatments in O₂ and Ar gas ambients. We also investigated the evolution of surface morphology of ICB deposited Y₂O₃ films upon annealing treatments. We observed that the root-mean-square (RMS) value of surface roughness measured by AFM increased with annealing time at 800℃ in O₂ ambient, while the change of surface roughness was not observed in Ar ambient. We also found the growth of SiO₂ layer and the formation of yttrium silicate layer. From the capacitance values (C_(acc)) measured by C-V measurements, the relative dielectric constant of Y₂O₃ film in metal-insulator-semiconductor (MIS) structure was estimated to be about 9.

        • DMF effect on the morphology and the luminescence properties of Y<sub>2</sub>O<sub>3</sub>:Eu<sup>3+</sup> red phosphor prepared by spray pyrolysis

          Jung, K.Y.,Kang, Y.C.,Park, Y.K. Korean Society of Industrial and Engineering Chemi 2008 Journal of industrial and engineering chemistry Vol.14 No.2

          N,N-Dimethylformamide (DMF) was used as a drying control chemical additive (DCCA) in spray pyrolysis in order to improve the luminous properties of Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles. It was found that the addition of DMF to the spray solution containing citric acid (CA) and ethylene glycol (EG) greatly enhances the photoluminescence intensity as well as the morphology of Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles. According to BET analysis, the surface area of Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles prepared from the solution containing only the organic additives was not reduced, whereas, the surface area of the Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles prepared from the solution containing both DMF and organic additives was decreased gradually as increasing the concentration of DMF. From these results, it was concluded that the adding of DMF to the spray solution containing the organic additives is a very effective way to reduce the porosity of phosphor particles, keeping the spherical morphology. As a result, the densification of porous structure led to greatly improve the photoluminescence intensity of Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles under ultraviolet (254nm) excitation. Finally, the prepared Y<SUB>2</SUB>O<SUB>3</SUB>:Eu particles with dense structure showed about 208% improved photoluminescence intensity compared with the particles which have a spherical shape but porous structure.

        • Korean diet: Characteristics and historical background

          Kim, S.H.,Kim, M.S.,Lee, M.S.,Park, Y.S.,Lee, H.J.,Kang, S.a.,Lee, H.S.,Lee, K.E.,Yang, H.J.,Kim, M.J.,Lee, Y.E.,Kwon, D.Y. Elsevier 2016 Journal of ethnic foods Vol.3 No.1

          Background: Korea has developed a unique food culture connected to its long agricultural history. Recently, interest in Korean food, especially regarding its health benefits, has greatly increased. However, there are insufficient resources and research available on the characteristics and definitions of Korean cuisine. Methods: Researchers and professors of the food and nutritional sciences in Korea began working together in April 2015 in order to establish cohesive definitions and concepts to be used in dialogue related to the Korean diet (K-diet). The 100 most representative Korean dishes (K-food) were selected by evaluating their role in tradition, culture, and health promotion. Results: Although the K-diet has been widely discussed in regard to raw ingredients, traditional cooking methods and technology, fundamental principles, and knowledge, it would be valuable to preserve the traditional methods and knowledge of Korean foods rather than focus on the raw materials themselves. Korean meals have historically been served with bap (cooked rice), kuk (dishes with broth), kimchi, and banchan (side dishes) to be consumed at the same time. As traditionally baking or frying were not common cooking methods, Koreans tended to use fermenting, boiling, blanching, seasoning, and pickling. Among these methods, the most characteristic method is fermentation. The process of fermentation enriches food flavors and preserves foods. Conclusion: The K-diet is composed of bab (cooked-rice) and kuk, and various banchan with one serving called bapsang. Kimchi is always served at every meal. The principal aspects of the K-diet include proportionally high consumption of vegetables, moderate to high consumption of legumes and fish, and low consumption of red meat. Banchan is mostly seasoned with various jang (fermented soy products), medicinal herbs, and sesame or perilla oil.

        • Novel effects of FTY720 on perinuclear reorganization of keratin network induced by sphingosylphosphorylcholine: Involvement of protein phosphatase 2A and G-protein-coupled receptor-12

          Park, M.K.,Park, S.,Kim, H.J.,Kim, E.J.,Kim, S.Y.,Kang, G.J.,Byun, H.J.,Kim, S.H.,Lee, H.,Lee, C.H. North-Holland ; Elsevier Science Ltd 2016 european journal of pharmacology Vol.775 No.-

          <P>Sphingosylphosphorylcholine (SPC) evokes perinuclear reorganization of keratin 8 (K8) filaments and regulates the viscoelasticity of metastatic cancer cells leading to enhanced migration. Few studies have addressed the compounds modulating the viscoelasticity of metastatic cancer cells. We studied the effects of sphingosine (SPH), sphingosine 1-phosphate (S1P), FTY720 and FTY720-phosphate (FTY720P) on SPC-induced K8 phosphorylation and reorganization using Western blot and confocal microscopy, and also evaluated the elasticity of PANC-1 cells by atomic force microscopy. FTY720, FTY720P, SPH, and SIP concentration-dependently inhibited SPC-evoked phosphorylation and reorganization of K8, and migration of PANC-1 cells. SPC triggered reduction and narrow distribution of elastic constant K and conversely, FTY720 blocked them. A common upstream regulator of JNK and ERK, protein phosphatase 2A (PP2A) expression was reduced by SPC, but was restored by FTY720 and FTY72P. Butyryl forskolin, a PP2A activator, suppressed SPC-induced K8 phosphorylation and okadaic acid, a PP2A inhibitor, induced K8 phosphorylation. Gene silencing of PP2A also led to K8 phosphorylation, reorganization and migration. We also investigated the involvement of GPR12, a high-affinity SPC receptor, in SPC-evoked keratin phosphorylation and reorganization. GPR12 siRNA suppressed the SPC-triggered phosphorylation and reorganization of K8. GPR12 overexpression stimulated keratin phosphorylation and reorganization even without SPC. FTY720 and FTY720P suppressed the GPR12-induced phosphorylation and reorganization of K8. The collective data indicates that FTY720 and FTY720P suppress SPC-induced phosphorylation and reorganization of K8 in PANC-1 cells by restoring the expression of PP2A via GPR12. These findings might be helpful in the development of compounds that modulate the viscoelasticity of metastatic cancer cells and various SPC actions. (C) 2016 Elsevier B.V. All rights reserved.</P>

        • 1987년 한국에서 발생한 렙토스피라병의 혈청역학적 조사

          이증훈,박영수,이우곤,김석용,정선식,우준희,박성광,박경희,송영욱,김선영,기정일,최두혁,강성귀,김주완,최강원,김우열,최명식,최인학,장우현,윤성열 대한감염학회 1988 감염 Vol.20 No.3

          Human leptospirosis was an unfamiliar disease in Korea until 1984 that outbreak of leptospirosis occurred among farmers and soldiers after field works for harvesting rice. During that time, Lee and Jo confirmed the first Korean cases of leptospirosis by serological test, isolation of causative agent and autopy findings. Afterward several outbreaks occurred also during autumn especially after flood in every years and some characterisitcs of leptospirosis in Korea such as clinical manifestations, serotypes and seroepidemiological features has been revealed by many investigators. Because of the major mode of transmission between rodents and human is by direct contact with leptospiral urine of rodents or contaminated soil by the urine, leptospirosis in Korea has been primarily a disease of person in occupations heavily exposed to contaminated soil or infected urine such as farmer, army and etc. Therefore it seems that leptospirosis is one of the main communicable diseases to be controlled urgently in Korea, for an agricultural people account for almost half of total Korean people. For clarifying the seroepidemiological patterns of human leptospirosis in Korea by sex, month region and main reacting serovars of L. interrogans among acute febrile disease occurred in 1987, 1,773 patient's sers with acute febrile episodes were tested by microagglutination test using 19 representative strains of leptospiral serogroup as antigen. All of those sera were collected from 10 collaborative clinics located in Kyunggi, Kangwon, Chungbuk, Chungnam, Chonbuk, Chonnam province and Seoul. The results wee summerized as follows. 1) Among 1,773 sera of patients with acute febrile episodes, 219 (12.4%) were seropositive to L. interrogans, 487(27.5%) to R. tsutsugamushi, 241(13.6%) to R.typhi and 160(90.0%) to Hantaan virus. 2) Among seropositives to L.interrogans, the male outnumbered the female, 65% and 35%. 3) For age distribution, 26.9% of seropositives to L.interrogans were fifties, 19.6% were forties, 9.1% were sixties, 5.9% were thirties and 4.1% were twenties. 4) Eighty three percent of seropositives had occurred between September and October in 1987 with a peak in September. 5) Main leptospiral serovars reactive to patient's sera were Icterohaemorrhagiae(54.3%), Canicola(31.0%), CH-48(13.2%), Tarassovi(0.9%)and Cynopteri(0.5%). 6) For regional distribution, 65.8% of seropositives to L.interrogans were residents from Chonbuk, 12.3% were Chonnam, 7.3% were Chungnam, 5.5% were Kyunggi and 1.4% were Kangwon.

        • 중년 사무직 남성의 직무스트레스와 허리둘레, 체질량지수의 관계에 관한 연구

          강수임,고보경,김지영,노정연,리청,송주은,이현영,이혜민,최유경,정덕유,이민경 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

          Purpose: The purpose of this study was to determine the relationship between job stress, body mass index and waist circumference among middle aged male workers. Methods: Using a descriptive correlation study design, a total of 122 middle aged male workers were recruited through convenience sampling from November 8 to December 13, 2015. The questionnaire included in this study were general characteristics and the Korean Occupational Stress Scale-Short Form (KOSS-SF). Data were statistically analyzed using SPSS windows version 22 program with Pearson’s correlation coefficient. Results: A significant relationship was found between job stress, body mass index (p=.043) and waist circumference (p=.007). Conclusion: These results suggest that high job stress are significantly associated with both body mass index and waist circumference of middle aged male workers. This implies a need for intervention that focuses on reducing obesity and metabolic syndrome influenced by job stress.

        • 대학생의 수면, 회복성과 대인관계 간의 관계

          강민경,김소정,김유미,박수민,변고영,송은혜,신지혜,이은별,이은서,정진선,김건희,이수연 이화여자대학교 간호과학대학 2019 이화간호학회지 Vol.- No.53

          Purpose: This study aimed to identify the relationship among sleep, resilience, and interpersonal relations of college students. Methods: Data were collected by using a structured questionnaire consisting of Korean Sleep Scale, Connor-Davidson Resilience Scale-10, and Relationship Change Scale between September 21st, 2018 to September 30th, 2018. Subjects were 185 college students who currently attend universities in a city. Collected data were analyzed using descriptive statistics, t-test, one-way ANOVA, Tukey’s test and Pearson’s correlation coefficient using the SPSS 25.0 program. Results: The mean score of sleep was 34.93±6.35, the mean score of resilience was 23.17±6.95, and the mean score of interpersonal relations were 3.65±0.38. In sleep, there were significant differences according to grade and major. In resilience, there were significant differences according to gender and grade. Sleep was negatively related to resilience (r=-.319, p<.001) and interpersonal relations (r=-.226, p=.002). Interpersonal relations were positively correlated to resilience (r=.348, p<.001). Conclusion: The results suggest that concrete measures to promote interpersonal relations need to be sought in consideration of the relations among college students' sleep, resilience, and interpersonal relations. Also, it is expected that the study will be used as basic data to improve the interpersonal relations of college students in the desirable direction by improving the sleep and resilience of college students.

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