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        • Improved Model Predictive Control for H-bridge Cascaded STATCOM

          Xu Rong,Yu Yong,Wu Jian,Yang Rongfeng,Xu Dianguo,Chen He,Yu Yannan,Ni Ronggang 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

          H-bridge cascaded static synchronous compensator (STATCOM) is often used to compensate the harmonic and reactive current derived from non-linear load. In order to improve the performance of STATCOM, an improved model predictive control (MPC) method is put forward in this paper. In the proposed MPC, the difference equations which are derived from the transfer functions of controlling variables and controlled variables in STATCOM are used as the predictive control model, the error between the output of STATCOM and predictive model is used to design feedback correction controller and rolling optimization controller. Meanwhile, the introduced repetitive controller is used to eliminate the inherent steady error. The actual H-bridge cascaded STATCOM is constructed and a series of verification tests are executed. The experimental results prove that the output voltage and current of H-bridge cascaded STATCOM with the proposed MPC have smaller distortion and better sinusoidal shape than those of the traditional Proportion Integral (PI) control. Moreover, the performance of H-bridge cascaded STATCOM is great in high power experiment.

        • KCI등재
        • Effect of Tissue Factor on Invasion Inhibition and Apoptosis Inducing Effect of Oxaliplatin in Human Gastric Cancer Cell

          Yu, Yong-Jiang,Li, Yu-Min,Hou, Xu-Dong,Guo, Chao,Cao, Nong,Jiao, Zuo-Yi Asian Pacific Organization for Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

          Objective: Tissue factor (TF) is expressed abnormally in certain types of tumor cells, closely related to invasion and metastasis. The aim of this study was to construct a human gastric cancer cell line SGC7901 stably-transfected with human TF, and observe effects on oxaliplatin-dependent inhibition of invasion and the apoptosis induction. Methods: The target gene TF was obtained from human placenta by nested PCR and introduced into the human gastric cell line SGC7901 through transfection mediated by lipofectamine. Stably-transfected cells were screened using G418. Examples successfully transfected with TF-pcDNA3 recombinant (experimental group), and empty vector pcDNA3 (control group) were incubated with oxaliplatin. Transwell chambers were used to show change in invasive ability. Caspase-3 activity was detected using a colorimetric method and annexin-V/PI double-staining was applied to detect apoptosis. Results: We generated the human gastric cancer cell line SGC7901/TF successfully, expressing TF stably and efficiently. Compared with the control group, invasion increased, whereas caspase-3 activity and apoptosis rate were decreased in the experimental group. Conclusion: TF can enhance the invasive capacity of gastric cancer cells in vitro. Its increased expression may reduce invasion inhibition and apoptosis-inducing effects of oxaliplatin and therefore may warrant targeting for improved chemotherapy.

        • SCIESCOPUSKCI등재

          Speed and Current Sensor Fault Detection and Isolation Based on Adaptive Observers for IM Drives

          Yu, Yong,Wang, Ziyuan,Xu, Dianguo,Zhou, Tao,Xu, Rong The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.5

          This paper focuses on speed and current sensor fault detection and isolation (FDI) for induction motor (IM) drives. A new, accurate and high-efficiency FDI approach is proposed so that a system can continue operating with good performance even in the presence of speed sensor faults, current sensor faults or both. The proposed three paralleled adaptive observers are capable of current sensor fault detection and localization. By using observers, the rotor flux and rotor speed can be estimated which allows the system to run under the speed sensorless vector control mode when a speed sensor fault occurs. In order to detect speed sensor faults, a threshold-based scheme is proposed. To verify the feasibility and effectiveness of the proposed FDI strategy, experiments are carried out under different conditions based on a dSPACE DS1104 induction motor drive platform.

        • KCI등재

          Speed and Current Sensor Fault Detection and Isolation Based on Adaptive Observers for IM Drives

          Yong Yu,Ziyuan Wang,Dianguo Xu,Tao Zhou,Rong Xu 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.5

          This paper focuses on speed and current sensor fault detection and isolation (FDI) for induction motor (IM) drives. A new, accurate and high-efficiency FDI approach is proposed so that a system can continue operating with good performance even in the presence of speed sensor faults, current sensor faults or both. The proposed three paralleled adaptive observers are capable of current sensor fault detection and localization. By using observers, the rotor flux and rotor speed can be estimated which allows the system to run under the speed sensorless vector control mode when a speed sensor fault occurs. In order to detect speed sensor faults, a threshold-based scheme is proposed. To verify the feasibility and effectiveness of the proposed FDI strategy, experiments are carried out under different conditions based on a dSPACE DS1104 induction motor drive platform.

        • SCIESCOPUSKCI등재후보

          Keratin 17 identified by proteomic analysis may be involved in tumor angiogenesis

          Xu, Yong,Zhang, Su-Zhen,Huang, Can-Hua,Liu, Xin-Yu,Zhong, Zhen-Hua,Hou, Wen-Li,Su, Zi-Fen,Wei, Yu-Quan Korean Society for Biochemistry and Molecular Biol 2009 BMB Reports Vol.42 No.6

          Angiogenesis is crucial for solid tumor growth. By secreting angiogenic factors, tumor cells induce angiogenesis. However, targeting these angiogenic factors for cancer therapy is not always successful, suggesting that other factors may be involved in tumor angiogenesis. This work shows that 25 protein spots were differentially expressed by two-dimensional gel electrophoretic analysis when HepG2 cells induced endothelial cell differentiation to tube in vitro, and most of them were upregulated. Twenty-one proteins were identified with MALDITOF-MS, and the other four were identified by LTQ-MS/MS. Keratins were identified as one class of these upregulated proteins. Further study indicated that the expression of keratin 17 in cultured endothelial cells is likely microenvironment regulated, because its expression can be induced by HepG2 cells and bFGF as well as serum in culture media. Increased expression of keratins in endothelial cells, such as keratin 17, may contribute to the angiogenesis induced by HepG2 cells.

        • SCIESCOPUSKCI등재

          Microstructure evolution and effect on deuterium retention in oxide dispersion strengthened tungsten during He<sup>+</sup> irradiation

          Ding, Xiao-Yu,Xu, Qiu,Zhu, Xiao-yong,Luo, Lai-Ma,Huang, Jian-Jun,Yu, Bin,Gao, Xiang,Li, Jian-Gang,Wu, Yu-Cheng Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.12

          Oxide dispersion-strengthened materials W-1wt%Pr<sub>2</sub>O<sub>3</sub> and W-1wt%La<sub>2</sub>O<sub>3</sub> were synthesized by wet chemical method and spark plasma sintering. The field emission scanning electron microscopy (FE-SEM) analysis, XRD and Vickers microhardness measurements were conducted to characterize the samples. The irradiations were carried out with a 5 keV helium ion beam to fluences up to 5.0 × 10<sup>21</sup> ions/m<sup>2</sup> under 600 ℃ using the low-energy ion irradiation system. Transmission electron microscopy (TEM) study was performed to investigate the microstructural evolution in W-1wt%Pr<sub>2</sub>O<sub>3</sub> and W-1wt%La<sub>2</sub>O<sub>3</sub>. At 1.0 × 10<sup>20</sup> He<sup>+</sup>/m<sup>2</sup>, the average loops size of the W-1wt%Pr<sub>2</sub>O<sub>3</sub> was 4.3 nm, much lower than W-1wt% La<sub>2</sub>O<sub>3</sub> of 8.5 nm. However, helium bubbles were not observed throughout in both doped W materials. The effects of pre-irradiation with 1.0 × 10<sup>21</sup> He<sup>+</sup>/m<sup>2</sup> on trapping of injected deuterium in doped W was studied by thermal desorption spectrometry (TDS) technique using quadrupole mass spectrometer. Compared with the samples without He<sup>+</sup> pre-irradiation, deuterium (D) retention of doped W materials increased after He<sup>+</sup> irradiation, whose retention was unsaturated at the damage level of 1.0 × 10<sup>22</sup>D<sub>2</sub><sup>+</sup>/m<sup>2</sup>. The present results implied that irradiation effect of He<sup>+</sup> ions must be taken into account to evaluate the deuterium retention in fusion material applications.

        • KCI등재

          Induces Vasodilatation of Rat Mesenteric Artery in vitro Mainly by Inhibiting Receptor-Mediated Ca2+-Influx and Ca2+-Release

          Yong-Xiao Cao,Jian-Pu Zheng,Jian-Yu He,Jie Li,Cang-Bao Xu,Lars Edvinsson 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.6

          The purpose of this study was to investigate the effect of atropine on peripheral vasodilation and the mechanisms involved. The isometric tension of rat mesenteric artery rings was recorded in vitro on a myograph. The results showed that atropine, at concentrations greater than 1 µM, relaxed the noradrenalin (NA)-precontracted rat mesenteric artery in a concentration-dependent manner. Atropine-induced vasodilatation was mediated, in part, by an endothelium-dependent mechanism, to which endothelium-derived hyperpolarizing factor may contribute. Atropine was able to shift the NA-induced concentration-response curve to the right, in a non-parallel manner, suggesting the mechanism of atropine was not mediated via the α1-adrenoreceptor. The β- adrenoreceptor and ATP sensitive potassium channel, a voltage dependent calcium channel, were not involved in the vasodilatation. However, atropine inhibited the contraction derived from NA and CaCl2 in Ca2+-free medium, in a concentration dependent manner, indicating the vasodilatation was related to the inhibition of extracellular Ca2+ influx through the receptoroperated calcium channels and intracellular Ca2+ release from the Ca2+ store. Atropine had no effect on the caffeine-induced contraction in the artery segments, indicating the inhibition of intracellular Ca2+ release as a result of atropine most likely occurs via the IP3 pathway rather than the ryanodine receptors. Our results suggest that atropine-induced vasodilatation is mainly from artery smooth muscle cells due to inhibition of the receptor-mediated Ca2+-influx and Ca2+- release, and partly from the endothelium mediated by EDHF.

        • SCIESCOPUSKCI등재

          Four Human Cases of Diphyllobothrium nihonkaiense (Eucestoda: Diphyllobothriidae) in China with a Brief Review of Chinese Cases

          Yu-Chun Cai,Shao-Hong Chen,Hiroshi Yamasaki,Jia-Xu Chen,Yan Lu,Yong-Nian Zhang,Hao Li,Lin Ai,Hai-Ning Chen 대한기생충학열대의학회 2017 The Korean Journal of Parasitology Vol.55 No.3

          We described 4 human infection cases of zoonotic fish-tapeworm, Diphyllobothrium nihonkaiense, identified with morphological and molecular characters and briefly reviewed Chinese cases in consideration of it as an emerging parasitic disease in China. The scolex and mature and gravid proglottids of some cases were seen, a rosette-shaped uterus was observed in the middle of the mature and gravid proglottids, and the diphyllobothriid eggs were yellowish-brown in color and displayed a small knob or abopercular protuberance on the opposite end of a lid-like opening. The average size of the eggs was recorded as 62-67×42-45 μm. The parasitic materials gathered from 4 human cases were morphologically identified as belonging to the genera Diphyllobothrium and Adenocephalus. The phylogenetic analysis based on the nucleotide sequences of cytochrome c oxidase subunit 1 gene of the etiologic agents confirmed that the 4 cases were D. nihonkaiense infection. The finding of 4 additional D. nihonkaiense cases suggests that D. nihonkaiense might be a major causative species of human diphyllobothriasis in China. A combined morphological and molecular analysis is the main method to confirm D. nihonkaiense infection.

        • KCI등재

          Metabolic dynamics across prolonged diapause development in larvae of the sawfly, Cephalcia chuxiongica (Hymenoptera: Pamphiliidae)

          Xu Rong,Chen Yu-Hui,Xia Ju-Fei,Zeng Ting-Xiao,Li Yong-He,Zhu Jia-Ying 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

          Nutrient metabolism is crucial for the survival of insects through the diapause. However, little is known about the metabolic mechanism of prolonged diapause. The sawfly, Cephalcia chuxiongica (Hymenoptera: Pamphilii�dae), is a notorious defoliator of pine trees in southwest China. One of the distinguishing biological character�istics of this pest is the prolonged diapause of about 1.5 years. In this study, the body lipid, carbohydrate (total body sugar, glycogen, trehalose, and glucose), protein, and glycerol contents were measured in diapausing larvae of C. chuxiongica. The results showed that the changes of biochemical composition in C. chuxiongica are asso�ciated with the diapause initiation, maintenance, and termination phases. During the initiation phase, trehalose, glucose, and glycerol increased significantly, but glycogen decreased sharply. In general, the lipid, carbohydrate, and glycerol levels decreased gradually across the maintenance phase. At termination phase, the contents of glycogen and lipid persistently decreased, while an increase of trehalose, glucose, and glycerol contents were detected. The protein level was significantly higher at maintenance phase than at initiation and termination phases. It was also found that elevation of trehalose, glucose, and glycerol contents occurred in winter. These implies that the metabolites with altered levels in diapausing larvae of C. chuxiongica are responsible for maintaining a prolonged development and overwintering.

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