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Fei-Fei Qin,Ya-Xiong Wang,Young-Bae Kim 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.춘계 No.-
고분자 전해질 연료전지의 열관리는 연료전지 작업 효율을 향상시키고 수명을 연장시키기는 매우 중요한 역할을 한다. 스택 온도가 너무 낮으면 전기 화학 반응의 속도가 늦어지고 반응에 의해 생성되는 물의 증발을 방해 한다. 그러나, 너무 높으면 온도는 촉매 낭비, 열 손실, 폐기물 방출 등 연료 전지의 수명을 줄인다. 본 논문은 고분자 전해질 연료전지(PEMFC) 열 관리를 위한 연구이다. 우선, 연료전지의 열역학 이론에 기초하여, MATLAB / Simulink를 통해 연료전지의 동적 모델을 만들었다. 실험을 통해 수학적인 시뮬레이션 모델링을 검증했다. PEMFC 동적 모델에 기초하여, 본 연구는 퍼지 논리 전략을 통하여 열 관리 제어 시스템을 설계 하였다. 이상적인 온도(PEMFC 효율 최적의 온도 곡선)와 스택 실제 온도의 오차, 그 오차의 미분 항, 및 외부 간섭 조건 전류(PEMFC 현재 스택)로 퍼지 제어기의 입력으로 구성 되었으며, 제어기의 출력은 냉각 팬의 제어전압이다. 본 연구는 열 관리를 위한 처음으로 외부 간섭 조전, 즉, 스택 전류를 제어기에 도입하여 복잡한 한 퍼지 제어기를 만들었다. 3차원 퍼지 제어기는 간단한 퍼지 제어기를 통해 발생한 정적 오류를 줄일 수 있다. 뿐만 아니라 제어 최적화 성능을 향상시켰다. 퍼지 논리 제어방법을 통해 연료전지 열 관리를 빠른 응답 시간과 작은 오차의 오버 슈트를 얻을 수 있다. 즉, 더 효율적으로 제어 성능을 향상시켰다.
Pan, Xiong-Fei,Xie, Yao,Loh, Marie,Yang, Shu-Juan,Wen, Yuan-Yuan,Tian, Zhi,Huang, He,Lan, Hui,Chen, Feng,Soong, Richie,Yang, Chun-Xia Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Objective: Gastric cancer (GC) is one of the most common malignancies and its mortality ranks third among all cancers in China. We previously noted that XRCC1 Arg194Trp was associated with GC risk in Western China in a study on XRCC1 Arg194Trp and ADPRT Val762Ala. We aimed to further explore the association of these polymorphisms with risk of the noncardia subtype. Methods: We enrolled 176 noncardia GC patients and 308 controls from four hospitals and a community between October 2010 and August 2011. Genotyping was performed in a 384-well plate format on the Sequenom MassARRAY platform. A self-designed questionnaire was utilized to collect epidemiological data from the subjects regarding demographic factors and potential risk factors. Results: Subjects were aged $56.8{\pm}11.8$ (mean ${\pm}$ standard deviation) and $57.6{\pm}11.1$ years in the case and control groups, respectively. Individuals carrying the XRCC1 Trp/Trp or Arg/Trp variant genotype were at significantly increased risk of noncardia GC (adjusted OR, 1.48; 95% CI, 1.00-2.17), after adjustment for family history of cancer, drinking, and smoking. The increased risk of XRCC1 Arg194Trp variant genotype was more pronounced among subjects below 60 years old (adjusted OR, 1.78; 95% CI, 1.07-2.96), compared to older individuals. ADPRT Val762Ala variants (Ala/Ala or Val/Ala) were not associated with noncardia GC (adjusted OR, 1.03; 95% CI, 0.69-1.54). Conclusions: Our study suggests that XRCC1 Arg194Trp is a genetic susceptibility factor for developing noncardia GC in Han Chinese in Western China. In particular, individuals with the XRCC1 Arg194Trp variant genotype are at increased risk for GC below 60 years old.
Ya-Xiong Wang,Fei-Fei Qin,Kai Ou,Young-Bae Kim 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
DC/DC converters with hybrid proton exchange membrane (PEM) fuel cell and battery power sources are designed and implemented using sliding mode control (SMC). The converters are typically comprised by unidirectional boost converter and bidirectional converter which are used for regulating the bus voltage and managing power distribution. SMC is selected to control the converters since it can cope with the high non-linear characteristic of the coupled system as well as ensure the stability. The hybrid power control system is constructed in MATLAB/Simulink platform. A comparative approach based on conventional proportional-integral (PI) control is developed to compare the control performance with SMC. The experimental validation is carried out with National Instruments (NI) LabVIEW-based hybrid PEMFC/battery supplied DC/DC converters system prototype.
Pan, Xiong-Fei,Wen, Ying,Loh, Marie,Wen, Yuan-Yuan,Yang, Shu-Juan,Zhao, Zhi-Mei,Tian, Zhi,Huang, He,Lan, Hui,Chen, Feng,Soong, Richie,Yang, Chun-Xia Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7
Background: Gastric carcinogenesis is a complicated process that involves environmental and genetic factors like interleukin-4 (IL-4) and IL-8. Single nucleotide polymorphisms in their genes are associated with changed levels of gene expression. Here, we investigated the association between IL4-590 C>T and IL8-251T>A and gastric cancer (GC) risk in Sichuan of Southwestern China. Materials and Methods: We surveyed the research subjects using a self-designed questionnaire with questions on demographic factors and putative risk factors. Approximately 2-5ml of whole blood was collected after field survey to analyze IL4-590 C>T and IL8-251T>A genotypes using MALDI-TOF MS. Results: Our study recruited 308 pairs of GC patients and controls, including 224 (72.7%) men and 84 (27.3%) women in each group. There were 99 cardia and 176 noncardia GC patients in the case group. The case and control groups had an average age of $57.7{\pm}10.6$ ($mean{\pm}SD$) and $57.6{\pm}11.1$ years. GC patients reported a significantly greater proportion of family history of cancer (29.9% vs 10.7%, p<0.01) and drinking (54.6% vs 43.2%, p<0.01) than did controls. Variant genotypes of IL-4-590 C>T and IL-8-251 T>A were not associated with overall GC risk (adjusted OR, 0.89; 95%CI, 0.61-1.28 for CT or CC vs TT; adjusted OR, 1.14; 95%CI, 0.86-1.79 for TA or AA vs TT). Stratification analysis of two SNPs for risk by subsites only found that variant IL-8-251 TA or AA genotype was associated with increased noncardia GC risk (adjusted OR, 2.58; 95%CI, 1.19-5.57). We did not observe interactions between the IL-8-251 T>A genotype and smoking (adjusted OR, 0.38; 95%CI, 0.08-1.79) or drinking (adjusted OR, 0.36; 95%CI, 0.08-1.65) for risk of noncardia GC. Conclusions: Our data indicate no association between the two SNPs of IL-4-590 and IL-8-251 with overall GC risk, while the IL-8-251 TA or AA genotype conferred risk of cardia GC. Our findings contribute to the evidence body for risk of SNPs associated with the development of gastric cancer in this region.
Yongjun Fei,Zhi-Xiong Liu,Hai-Yan Xiong,Lai-Yun Li 한국식물학회 2018 Journal of Plant Biology Vol.61 No.1
Arabidopsis AGAMOUS (AG) has roles in specifying reproductive organ (stamens and carpels) identity, floral meristem determinacy, and repression of A-function. To investigate possible roles of AG orthologous genes in gymnosperm species and evolution of C function, we isolated and identified AG orthologous gene TcAG from Taxus chinensis var. mairei (family Taxaceae, order Coniferales), a member of the last divergant lineage from higher Conifer that sisters to Gnetales. Sequence alignment and phylogenetic analysis grouped TcAG into the gymnosperm AG lineage. TcAG was expressed in both developing male and female cones, but there was no expression in juvenile leaves. Ectopic expression of TcAG in an Arabidopsis ag mutant produced flowers with the third whorl petaloid stamen and fourth whorl normal carpel, but failed to convert first whorl sepals into carpeloid organs and second whorl petals into stamenoid organs. A 35S::TcAG transgenic Arabidopsis ag mutant had very early flowering, and produced a misshapen inflorescence with a shortened floral axis. Our results suggest that establishment of the complete C-function occurred gradually during AG lineage evolution even in gymnosperms.
Pan, Xiong-Fei,Yang, Shu-Juan,Loh, Marie,Xie, Yao,Wen, Yuan-Yuan,Tian, Zhi,Huang, He,Lan, Hui,Chen, Feng,Soong, Richie,Yang, Chun-Xia Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4
Objectives: Interleukin (IL) -10 is a potent cytokine with a dual ability to immunosuppress or immunostimulate. We aimed to explore the association of IL10 promoter polymorphisms with risk of gastric cancer (GC) in a Han population in Southwestern China. Methods: We enrolled 308 pairs of GC and control subjects from four hospitals and a community between October 2010 and August 2011 in a 1:1 matched case-control design. Demographic information was collected using a designed questionnaire. IL10-592 A>C and IL10-1082 A>G polymorphisms were determined by Sequenom MassARRAY analysis. Results: Patients with GC reported statistically higher proportions of family history of cancer (29.9% versus 10.7%, P<0.01) and alcohol drinking (54.6% versus 43.2%, P<0.01) than did controls. Similar results were observed in comparison between non-cardia GC patients and controls (P<0.01 and P=0.03). Variant genotypes of IL10-592 A>C and IL10-1082 A>G were not associated with overall GC risk (adjusted OR, 0.94, 95% CI, 0.66-1.33; adjusted OR, 1.00, 95% CI, 0.62-1.60). Sub-analysis showed that the IL10-592 AC/CC variant genotype was associated with decreased non-cardia GC risk (adjusted OR, 0.58; 95% CI, 0.36-0.95). No association was found between any of the IL10 haplotypes established from two polymorphisms and risk of non-cardia GC. Conclusions: In conclusion, our data do not link the two SNPs of IL10-592 and IL10-1082 with overall GC risk. We demonstrate that IL10-592 polymorphism is associated with protective effect against non-cardia GC. Our findings may offer insight into risk associated with the development of GC in this region.