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Diverse nectar robbers on Alpinia roxburghii Sweet (Zingiberaceae)
Xiaobao Deng,Wen Deng,Alice Catherine Hughes,Dharmalingam Mohandass 국립중앙과학관 2015 Journal of Asia-Pacific Biodiversity Vol.8 No.3
This study records for the first time three mammal species as nectar robbers on the ginger Alpinia roxburghii Sweet. We examined the behavior of nectar robbers and compared with earlier studies on a single plant species. We recorded seven species of nectar robbers: three squirrels, one bird, and three bees. Timing of robbing nectars were similar; however, robbing behavior differed among robbers. In particular, squirrels damaged the flower parts while robbing the nectar.
Cheng Xiaobao,Gao Minghan,Gao Qiang,Peng Xiao-Hong 한국통신학회 2023 ICT Express Vol.9 No.6
Reinforcement learning (RL) has been used in combination with cooperative caching to deal with growing traffic in mobile networks, but the performance of RL based caching policies depends heavily on network settings. This paper investigates the impact of access delays within network infrastructures and popularity and similarity properties of the contents requested on network performance. A deep Q-network based caching framework is established in both basic and extended cooperative edge networks. Our simulation results reveal explicit relationships between the performance and influential parameters, which can provide a guidance and benchmark for the design of effective caching polices with RL and cooperation technologies.
Feng Lin,Xiaobao Wu 한국콘크리트학회 2016 International Journal of Concrete Structures and M Vol.10 No.4
Experimental studies were conducted on 36 grouted splices to investigate their mechanical performance under four loading schemes: (1) incremental tensile loading, (2) repeated tensile loading, (3) cyclic loading at high stress, and (4) cyclic loading at large strain. Load-deformation responses of the grouted splices under cyclic loadings were featured with pinching effect and stiffness degradation compared to those responses under tensile loadings. The shape of the hysteresis loops of load-deformation curves was similar to that under incremental tensile loading. For the purpose of structural analysis, stress–strain relationships were presented for grouted splices under various loadings.
Yina Ren,Xiaobao Xu,Qianlan Zhang,Yongzhuang Lu,Ximin Li,Lin Zhang,Jingkui Tian 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.2
One new oleanolic acid triterpenoid saponin,3-O-b-D-glucopyranosyl olean-11, 13(18)-diene-23,28-dioicacid, (hereafter referred to as DS-1) was isolated from thetraditional Chinese medicinal plant Dianthus superbus (D. superbus). DS-1 plays an important role in the bioactivity ofD. superbus. Thus, a sensitive, reliable and accuratereversed-phased liquid chromatography with tandem massspectrometry (LC–MS/MS) in negative ion mode wasdeveloped and validated for the quantification and pharmacokineticstudy of DS-1 in rats plasma. The pharmacokineticprofile showed that DS-1 was rapidly absorbed and eliminatedin plasma, indicating that significant accumulation ofthe compound in biological specimen is unlikely. In addition,poor absorption into systemic circulation was observed afteroral administration of DS-1, resulting in low absolute bioavailability(0.92 %).
Lin, Feng,Wu, Xiaobao Korea Concrete Institute 2016 International Journal of Concrete Structures and M Vol.10 No.4
Experimental studies were conducted on 36 grouted splices to investigate their mechanical performance under four loading schemes: (1) incremental tensile loading, (2) repeated tensile loading, (3) cyclic loading at high stress, and (4) cyclic loading at large strain. Load-deformation responses of the grouted splices under cyclic loadings were featured with pinching effect and stiffness degradation compared to those responses under tensile loadings. The shape of the hysteresis loops of load-deformation curves was similar to that under incremental tensile loading. For the purpose of structural analysis, stress-strain relationships were presented for grouted splices under various loadings.
Multibody contact dynamics on mechanisms with deep groove ball bearing joints
Tingqiang Yao,Liguo Xian,Lihua Wang,Xiaobao Liu 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.9
The dynamics of ball bearings are important to fatigue breakage, dynamic performance and motion precision of mechanisms connected by ball bearings joints with multi-clearances. In this study, a new method is proposed for multibody dynamics analysis on mechanisms under the effects of radial internal clearances and impact of balls/cage pockets interactions of ball bearings. Including balls/rings interactions and balls/cage pockets interactions, the three dimensional dynamics models of the crank slider mechanism are established and calculated by generalized-α algorithms on the basis of Hertzian contact theory and penalty function method. The rules of eccentric trajectories of inner and outer ring center for one ball bearing joint are verified with the results calculated by XU’s references. The results of dynamic errors, motion trajectories, dynamic forces are achieved under different speeds, radial clearances and number of ball bearings. The speeds and radial clearances are critical to the dynamic performances and motion precision of mechanisms, especially the number of ball bearings. The number of ball bearings is important to impact force and motion stability of the mechanism.
An optofluidic system with integrated microlens arrays for parallel imaging flow cytometry
Holzner, Gregor,Du, Ying,Cao, Xiaobao,Choo, Jaebum,J. deMello, Andrew,Stavrakis, Stavros The Royal Society of Chemistry 2018 Lab on a chip Vol.18 No.23
<P>In recent years, high-speed imaging has become increasingly effective for the rapid analysis of single cells in flowing environments. Single cell imaging methods typically incorporate a minimum magnification of 10× when extracting sizing and morphological information. Although information content may be significantly enhanced by increasing magnification, this is accompanied by a corresponding reduction in field of view, and thus a decrease in the number of cells assayed per unit time. Accordingly, the acquisition of high resolution data from wide field views remains an unsolved challenge. To address this issue, we present an optofluidic flow cytometer integrating a refractive, microlens array (MLA) for imaging cells at high linear velocities, whilst maximizing the number of cells per field of view. To achieve this, we adopt an elasto-inertial approach for cell focusing within an array of parallel microfluidic channels, each equipped with a microlens. We characterize the optical performance of the microlenses in terms of image formation, magnification and resolution using both ray-tracing simulations and experimental measurements. Results demonstrate that the optofluidic platform can efficiently count and magnify micron-sized objects up to 4 times. Finally, we demonstrate the capabilities of the platform as an imaging flow cyclometer, demonstrating the efficient discrimination of hB and Jurkat cells at throughputs up to 50 000 cells per second.</P>
GETACHEW ALEMU,MINGKUI WANG,BINGYAN ZHANG,JUNPENG LI,XIAOBAO XU,JIN CUI,YAN SHEN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.5
The power conversion e±ciency of p-type dye-sensitized solar cells (DSSC) is determined by thekinetics of hole injection and dye-regeneration reaction at the dye/electrolyte interface. In thiswork, the photochemical regeneration kinetics of dye adsorbed on CuCrO 2 mesoporous ¯lm wasinvestigated by using scanning electrochemical microscopy with feedback mode. Organic P1 andC343 sensitizers in combination with iodide-based and thiolate-based electrolytes were selected tounderstand the e®ect of sensitizers and redox shuttles on dye-regeneration process. A fast re-generation kinetic rate constant was con¯rmed in thiolate-based sample compared with iodide-based electrolyte, indicating that the organic redox shuttle was an e±cient mediator to optimizethe performance of p-type DSSC.
Chongwen Xu,Yuan Shao,Wanli Ren,Hao Dai,Fangli Yang,Xiang Li,Shaoqiang Zhang,Junsong Liu,Xiaobao Yao,Qian Zhao,Xin Sun,Zhiwei Zheng 한국분자세포생물학회 2023 Molecules and cells Vol.46 No.6
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid carcinoma. Despite a good prognosis, approximately a quarter of PTC patients are likely to relapse. Previous reports suggest an association between S-phase kinase-associated protein 2 (SKP2) and the prognosis of thyroid cancer. SKP1 is related to apoptosis of PTC cells; however, its role in PTC remains largely elusive. This study aimed to understand the expression and molecular mechanism of SKP2 in PTC. SKP2 expression was upregulated in PTC tissues and closely associated with clinical diagnosis. In vitro and in vivo knockdown of SKP2 expression in PTC cells suppressed cell growth and proliferation and induced apoptosis. SKP2 depletion promoted cell autophagy under glucose deprivation. SKP2 interacted with PH domain leucine-rich repeat protein phosphatase-1 (PHLPP1), triggering its degradation by ubiquitination. Furthermore, SKP2 activates the AKT-related pathways via PHLPP1, which leads to the cytoplasmic translocation of SKP2, indicating a reciprocal regulation between SKP2 and AKT. In conclusion, the upregulation of SKP2 leads to PTC proliferation and survival, and the regulatory network among SKP2, PHLPP1, and AKT provides novel insight into the molecular basis of SKP2 in tumor progression.