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- 저자 : Xiao‑Xue Zhang (검색결과 83 건)
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Xue‑Lian Song,Fei‑Fei Zhang,Wen‑Jing Wang,Xin‑Ning Li,Yi Dang,Ying‑Xiao Li,Qian Yang,Mei‑Jing Shi,Xiao‑Yong Qi 한국유전학회 2020 Genes & Genomics Vol.42 No.12
Background: Myocardial ischemia and reperfusion injury (MI/RI) is a complex pathophysiological process, which can lead to severe myocardial injury. The long noncoding RNA alpha-2-macroglobulin antisense RNA 1 (A2M-AS1) has been revealed to be abnormally expressed in MI, However, its function in MI and the potential mechanism are still unclear. Objective: To evaluate the functional role of A2M-AS1 in hypoxia/reoxygenation (H/R)-induced neonatal cardiomyocytes and its potential molecular mechanism. Methods: Dataset GSE66360 was obtained from GEO database for analyzing the RNA expression of A2M-AS1 and interleukin 1 receptor type 2 (IL1R2). KEGG pathway enrichment analysis of the genes that co-expressed with A2M-AS1 was performed. Human neonatal cardiomyocytes were subjected to H/R to construct in vitro models. QRT-PCR and Western blot were adopted to test the levels of mRNA and protein. The viability and apoptosis of cardiomyocytes were tested by CCK-8 and flow cytometry assays, respectively. Results: The expression of A2M-AS1 was notably downregulated in H/R-treated cardiomyocytes. Overexpression of A2M-AS1 can notably enhance the cell viability of H/R-damaged cardiomyocytes, whereas knockdown of A2M-AS1 showed the opposite outcomes. Besides, a negative correlation was showed between A2M-AS1 and IL1R2 expression. In H/R-treated cardiomyocytes, overexpression of IL1R2 weakened the promoting proliferation and anti-apoptosis effects caused by overexpressing A2M-AS1, however, IL1R2-knockdown abolished the anti-proliferation and pro-apoptosis effects caused by silencing A2M-AS1. Conclusion: This study demonstrates the potential regulatory role of A2M-AS1/ IL1R2 axis in cardiomyocytes suffered from H/R, and provides insight into the protection of MI/RI.
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Study on economic performances of multi-span suspension bridges part 2: parametric study
Zhang, Li-Wen,Xiao, Ru-Cheng,Sun, Bin,Jiang, Yang,Zhang, Xue-Yi,Zhuang, Dong-Li,Zhou, Yun-Gang,Tu, Xue Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.2
Economic performances of consecutive multi-span suspension bridges are studied. The material amount and cost estimation formulas of the bridges have been derived in the part 1 of the study. A parametric study is carried out based on the formulas for investigating the different factors' effect on the bridge cost. The factors include the bridge sag, the bridge span, the bridge foundation and the environment condition, etc. Then, an economical layout of the bridges is proposed for different conditions. Lastly, a selection of suspension bridge types is discussed based on the economy of bridges.
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Taxonomy of fungal complex causing red-skin root of Panax ginseng in China
Xiao H. Lu,Xi M. Zhang,Xiao L. Jiao,Jianjun J. Hao,Xue S. Zhang,Yi Luo,Wei W. Gao 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.3
Background: Red-skin root of Asian ginseng (Panax ginseng) significantly reduces the quality and limits theproduction of ginseng in China. The disease has long been thought to be a noninfectious physiologicaldisease, except one report that proved itwas an infectious disease. However, the causal agents have not beensuccessfully determined. In the present study, we were to reveal the pathogens that cause red-skin disease. Methods: Ginseng roots with red-skin root symptoms were collected from commercial fields in NortheastChina. Fungi were isolated from the lesion and identified based on morphological characters alongwith multilocus sequence analyses on internal transcription spacer, b-tubulin (tub2), histone H3 (his3),and translation elongation factor 1a (tef-1a). Pathogens were confirmed by inoculating the isolates inginseng roots. Results: A total of 230 isolates were obtained from 209 disease samples. These isolates were classifiedinto 12 species, including Dactylonectria sp., D. hordeicola, Fusarium acuminatum, F. avenaceum, F. solani,F. torulosum, Ilyonectria mors-panacis, I. robusta, Rhexocercosporidium panacis, and three novel speciesI. changbaiensis, I. communis, and I. qitaiheensis. Among them, I. communis, I. robusta, and F. solani had thehighest isolation frequencies, being 36.1%, 20.9%, and 23.9%, respectively. All these species isolated werepathogenic to ginseng roots and caused red-skin root disease under appropriate condition. Conclusion: Fungal complex is the causal agent of red-skin root in P. ginseng.
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Reliable control of magnetic vortex chirality in asymmetrically optimized magnetic nanodisk
Zhang Huanhuan,Yu Hai,Zhang Xue-Feng,Yang Xiao-Xue,Shim Je-Ho,Ma Xiao-Ping,Piao Hong-Guang 한국물리학회 2022 Current Applied Physics Vol.43 No.-
Magnetic vortex has attracted attention in the field of information storage because their topological spin structures with chiral bistable states. If the vortex core polarity and vortex circulation sense can be controlled simultaneously in a nanodisk, which will be more beneficial to realize the multi-bit ultrahigh density storage. In this paper, a reliable control scheme for magnetic vortex chirality is proposed by optimizing the structure of Pac- Man-like nanodisk. The results show that the polarity and circulation of the vortex can be controlled simultaneously by changing the direction of the global magnetic field, and even the chiral states of the vortex can be determined by detecting the stray field distribution on the surface of the nanodisk. The optimized Pac-Man-like nanodisk provide an experimental method for the control and detection of magnetic vortex chirality, which will be beneficial to the realization of multi-bit magnetic storage or magnetic logic technology in the future.
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Xiao-Wen Zhang,Hua-Ping Lin,Jun Li,Fan Zhou,Bin Wei,Xue-Yin Jiang,Zhi-Lin Zhang 한국물리학회 2012 Current Applied Physics Vol.12 No.5
Microcavity effect and pixel contrast ratio (PCR) are key issues for top-emitting organic light-emitting diode (TOLED). Si and Ag are two widely used reflective anodes for constructing effective TOLEDs. The mechanism contributing to microcavity effect and PCR has been clarified by using conventional optoelectronic theory. Consequently, the differences of microcavity effect and PCR between Si-based and Agbased TOLEDs are discovered. Our results indicate that the Si-based TOLED possesses weak microcavity effect and improved PCR in comparison with Ag-based device. This is resulted from the low reflectivity and less reflective phase change of Si. The weak microcavity effect in Si-based TOLED also contributes to negligible variation of electroluminescent spectra with viewing angles and low device efficiency. Furthermore, Si-based TOLED shows rather high PCR which is about quintuple that of Ag-based device. Microcavity effect and pixel contrast ratio (PCR) are key issues for top-emitting organic light-emitting diode (TOLED). Si and Ag are two widely used reflective anodes for constructing effective TOLEDs. The mechanism contributing to microcavity effect and PCR has been clarified by using conventional optoelectronic theory. Consequently, the differences of microcavity effect and PCR between Si-based and Agbased TOLEDs are discovered. Our results indicate that the Si-based TOLED possesses weak microcavity effect and improved PCR in comparison with Ag-based device. This is resulted from the low reflectivity and less reflective phase change of Si. The weak microcavity effect in Si-based TOLED also contributes to negligible variation of electroluminescent spectra with viewing angles and low device efficiency. Furthermore, Si-based TOLED shows rather high PCR which is about quintuple that of Ag-based device.
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Study on economic performances of multi-span suspension bridges part 1: simple estimation formulas
Zhang, Li-Wen,Xiao, Ru-Cheng,Sun, Bin,Jiang, Yang,Zhang, Xue-Yi,Zhuang, Dong-Li,Zhou, Yun-Gang,Tu, Xue Techno-Press 2013 Structural Engineering and Mechanics, An Int'l Jou Vol.47 No.2
A study on economic performances of consecutive multi-span suspension bridges is carried out. In this part of the study, material amount and structural cost estimation formulas of the bridges is derived based on the structural ultimate carrying capacity. The bridge cost includes the part of superstructure and the part of substructure. Three types of bridge foundations, bored piles, concrete caissons and floating foundations, are considered in substructure. These formulas are to be used for the parametric study of the bridge cost in order to define its more economical layout under different conditions in the part two of the study.
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Zhang Hongrui,Zhang Liyang,Xue Xiao,Zhang Xiaoxia,Wang Hongyi,Gao Tengyun,Phillips Clive 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.1
Objective: The objective of this study was to compare the feeding value, meat nutrients and associative effects of a diet comprised of various corn silages inclusion with peanut vine or wheat straw in finishing beef cattle. Methods: One hundred and eighty Simmental crossbred beef steers were blocked and assigned to the follow treatments: i) whole plant corn silage-based diet (control, WPCS), ii) mixed forages-based diet (replacing a portion of corn silage with wheat straw, WPCSW), iii) corn stalklage-based diet (CS), and iv) sweet corn stalklage-based diet (SCS). Each group consisted of 5 repeated pens with 9 steers/pen. The diets were formulated to be isonitrogenous and isoenergetic with same forage to concentrate ratio. Experimental diets were fed for 90 d. Results: The effective ruminal degradability of dry matter and crude protein were highest for WPCS diet (p<0.05), for neutral detergent fiber was highest in SCS diet (p<0.05). The average daily gain was greater for cattle offered the WPCS diet, intermediate with WPCSW and SCS and lowest with CS (p<0.001). The concentration of non-esterified fatty acid in serum was higher for steers fed with CS and SCS diets than those offered WPCS and WPCSW steers (p<0.001). The treatments did not affect the general nutritional contents and amino acids composition of Longissimus dorsi of steers (p>0.05). Conclusion: The corn silage-based diet exhibited the highest feeding value. The sweet corn stalklage and wheat straw as an alternative to corn silage offered to beef cattle had limited influence on feeding value and meat nutrients. However, the value of a corn stalklage-based diet was relatively poor. To sum up, when the high quality forage resources, such as corn silage, are in short supply, or the growth rate of beef cattle decreases in the later finishing period, the sweet stalklage and wheat straw could be used as a cheaper alternative in feedlot cattle diet without sharp reducing economic benefits. Objective: The objective of this study was to compare the feeding value, meat nutrients and associative effects of a diet comprised of various corn silages inclusion with peanut vine or wheat straw in finishing beef cattle.Methods: One hundred and eighty Simmental crossbred beef steers were blocked and assigned to the follow treatments: i) whole plant corn silage-based diet (control, WPCS), ii) mixed forages-based diet (replacing a portion of corn silage with wheat straw, WPCSW), iii) corn stalklage-based diet (CS), and iv) sweet corn stalklage-based diet (SCS). Each group consisted of 5 repeated pens with 9 steers/pen. The diets were formulated to be isonitrogenous and isoenergetic with same forage to concentrate ratio. Experimental diets were fed for 90 d.Results: The effective ruminal degradability of dry matter and crude protein were highest for WPCS diet (p<0.05), for neutral detergent fiber was highest in SCS diet (p<0.05). The average daily gain was greater for cattle offered the WPCS diet, intermediate with WPCSW and SCS and lowest with CS (p<0.001). The concentration of non-esterified fatty acid in serum was higher for steers fed with CS and SCS diets than those offered WPCS and WPCSW steers (p<0.001). The treatments did not affect the general nutritional contents and amino acids composition of Longissimus dorsi of steers (p>0.05).Conclusion: The corn silage-based diet exhibited the highest feeding value. The sweet corn stalklage and wheat straw as an alternative to corn silage offered to beef cattle had limited influence on feeding value and meat nutrients. However, the value of a corn stalklage-based diet was relatively poor. To sum up, when the high quality forage resources, such as corn silage, are in short supply, or the growth rate of beef cattle decreases in the later finishing period, the sweet stalklage and wheat straw could be used as a cheaper alternative in feedlot cattle diet without sharp reducing economic benefits.
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Taxonomy of fungal complex causing red-skin root of Panax ginseng in China
Lu, Xiao H.,Zhang, Xi M.,Jiao, Xiao L.,Hao, Jianjun J.,Zhang, Xue S.,Luo, Yi,Gao, Wei W. The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.3
Background: Red-skin root of Asian ginseng (Panax ginseng) significantly reduces the quality and limits the production of ginseng in China. The disease has long been thought to be a noninfectious physiological disease, except one report that proved it was an infectious disease. However, the causal agents have not been successfully determined. In the present study, we were to reveal the pathogens that cause red-skin disease. Methods: Ginseng roots with red-skin root symptoms were collected from commercial fields in Northeast China. Fungi were isolated from the lesion and identified based on morphological characters along with multilocus sequence analyses on internal transcription spacer, β-tubulin (tub2), histone H3 (his3), and translation elongation factor 1α (tef-1α). Pathogens were confirmed by inoculating the isolates in ginseng roots. Results: A total of 230 isolates were obtained from 209 disease samples. These isolates were classified into 12 species, including Dactylonectria sp., D. hordeicola, Fusarium acuminatum, F. avenaceum, F. solani, F. torulosum, Ilyonectria mors-panacis, I. robusta, Rhexocercosporidium panacis, and three novel species I. changbaiensis, I. communis, and I. qitaiheensis. Among them, I. communis, I. robusta, and F. solani had the highest isolation frequencies, being 36.1%, 20.9%, and 23.9%, respectively. All these species isolated were pathogenic to ginseng roots and caused red-skin root disease under appropriate condition. Conclusion: Fungal complex is the causal agent of red-skin root in P. ginseng.
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