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Xiangang Zuo,Pengfei Liu 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.3
The development process of the software system is influenced by multi factors, thus the risk control of software projects is of vital importance. Targeting at the features including multi-factor, multilayer, fuzziness and uncertainty during the process of risk assessment of software projects, this paper analyzed the risk measurement of software projects and proposed a multilevel risk measurement algorithm of software projects based on grey variable weight clustering model. This algorithm firstly analyzed the influencing factors of the risk control of software projects, establishing a multilevel risk measurement system for software projects; next, establishing the whitenization weight functions of different measurement indexes and different measurement grades of software projects risks respectively on the basis of the grey system theory, and under the condition of considering the degree of importance of the indexes of different levels, the corresponding risk measurement algorithm of software projects based on grey variable weight clustering model was established; then the paper presented the detailed execution steps of this algorithm and discussed the detailed process to achieve the algorithm. Finally, the algorithm was verified through the case study.
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Xiaolei Ren,Xiangang Zuo,Kangzhen Xu,Yinghui Ren,Jie Huang,Jirong Song,Bozhou Wang,Fengqi Zhao 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.7
A novel energetic material, 1-amino-1-(2,4-dinitrophenylhydrazinyl)-2,2-dinitroethylene (APHDNE), was synthesized by the reaction of 1,1-diamino-2,2-dinitroethylene (FOX-7) and 2,4-dinitrophenylhydrazine in Nmethyl pyrrolidone (NMP) at 110 ^oC. The theoretical investigation on APHDNE was curried out by B3LYP/6-311+G^* method. The IR frequencies analysis and NMR chemical shifts were performed and compared with the experimental results. The thermal behavior of APHDNE was studied by DSC and TG/DTG methods, and can be divided into two crystal phase transition processes and three exothermic decomposition processes. The enthalpy, apparent activation energy and pre-exponential factor of the first exothermic decomposition reaction were obtained as −525.3 kJ mol^−1, 276.85 kJ mol^−1 and 10^(26.22) s^−1, respectively. The critical temperature of thermal explosion of APHDNE is 237.7 ^oC. The specific heat capacity of APHDNE was determined with micro-DSC method and theoretical calculation method, and the molar heat capacity is 363.67 J mol^−1 K^−1 at 298.15 K. The adiabatic time-to-explosion of APHDNE was also calculated to be a certain value between 253.2-309.4 s. APHDNE has higher thermal stability than FOX-7.
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( Kun Wang ),( Xiangang Kong ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5
This study aimed to explore the neuroprotection and mechanism of isoflurane on rats with spinal cord ischemic injury. Total 40 adult male Sprague-Dawley rats were divided into the four groups (n=10). Group A was sham-operation group; group B was ischemia group; group C was isoflurane preconditioning group; group D was isoflurane preconditioning followed by ischemia treatment group. Then the expressions of TWIK-related K+ channel 1 (TREK1) in the four groups were detected by immunofluorescent assay, real time-polymerase chain reactions (RT-PCR) and western blot. The primary neurons of rats were isolated and cultured under normal and hypoxic conditions. Besides, the neurons under two conditions were transfected with green fluorescent protein (GFP)-TREK1 and lentivirual to overexpress and silence TREK1. Additionally, the neurons were treated with isoflurane or not. Then caspase-3 activity and cell cycle of neurons under normal and hypoxic conditions were detected. Furthermore, nicotinamide adenine dinucleotide hydrate (NADH) was detected using NAD+/NADH quantification colorimetric kit. Results showed that the mRNA and protein expressions of TREK1 increased significantly in group C and D. In neurons, when TREK1 silenced, isoflurane treatment improved the caspase-3 activity. In hypoxic condition, the caspase-3 activity and sub-G1 cell percentage significantly increased, however, when TREK1 overexpressed the caspase-3 activity and sub-G1 cell percentage decreased significantly. Furthermore, both isoflurane treatment and overexpression of TREK1 significantly decreased NADH. In conclusion, isofluraneinduced neuroprotection in spinal cord ischemic injury may be associated with the up-regulation of TREK1.
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Wang, Kun,Kong, Xiangang The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5
This study aimed to explore the neuroprotection and mechanism of isoflurane on rats with spinal cord ischemic injury. Total 40 adult male Sprague-Dawley rats were divided into the four groups (n=10). Group A was sham-operation group; group B was ischemia group; group C was isoflurane preconditioning group; group D was isoflurane preconditioning followed by ischemia treatment group. Then the expressions of TWIK-related $K^+$ channel 1 (TREK1) in the four groups were detected by immunofluorescent assay, real time-polymerase chain reactions (RT-PCR) and western blot. The primary neurons of rats were isolated and cultured under normal and hypoxic conditions. Besides, the neurons under two conditions were transfected with green fluorescent protein (GFP)-TREK1 and lentivirual to overexpress and silence TREK1. Additionally, the neurons were treated with isoflurane or not. Then caspase-3 activity and cell cycle of neurons under normal and hypoxic conditions were detected. Furthermore, nicotinamide adenine dinucleotide hydrate (NADH) was detected using NAD+/NADH quantification colorimetric kit. Results showed that the mRNA and protein expressions of TREK1 increased significantly in group C and D. In neurons, when TREK1 silenced, isoflurane treatment improved the caspase-3 activity. In hypoxic condition, the caspase-3 activity and sub-G1 cell percentage significantly increased, however, when TREK1 overexpressed the caspase-3 activity and sub-G1 cell percentage decreased significantly. Furthermore, both isoflurane treatment and overexpression of TREK1 significantly decreased NADH. In conclusion, isoflurane-induced neuroprotection in spinal cord ischemic injury may be associated with the up-regulation of TREK1.
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Ren, Xiaolei,Zuo, Xiangang,Xu, Kangzhen,Ren, Yinghui,Huang, Jie,Song, Jirong,Wang, Bozhou,Zhao, Fengqi Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.7
A novel energetic material, 1-amino-1-(2,4-dinitrophenylhydrazinyl)-2,2-dinitroethylene (APHDNE), was synthesized by the reaction of 1,1-diamino-2,2-dinitroethylene (FOX-7) and 2,4-dinitrophenylhydrazine in N-methyl pyrrolidone (NMP) at 110 $^{\circ}C$. The theoretical investigation on APHDNE was curried out by B3LYP/6-311+$G^*$ method. The IR frequencies analysis and NMR chemical shifts were performed and compared with the experimental results. The thermal behavior of APHDNE was studied by DSC and TG/DTG methods, and can be divided into two crystal phase transition processes and three exothermic decomposition processes. The enthalpy, apparent activation energy and pre-exponential factor of the first exothermic decomposition reaction were obtained as -525.3 kJ $mol^{-1}$, 276.85 kJ $mol^{-1}$ and $10^{26.22}s^{-1}$, respectively. The critical temperature of thermal explosion of APHDNE is 237.7 $^{\circ}C$. The specific heat capacity of APHDNE was determined with micro-DSC method and theoretical calculation method, and the molar heat capacity is 363.67 J $mol^{-1}K^{-1}$ at 298.15 K. The adiabatic time-to-explosion of APHDNE was also calculated to be a certain value between 253.2-309.4 s. APHDNE has higher thermal stability than FOX-7.
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Shen Qiaoqiao,Luo Xiangping,Feng Xiangang,Gao Yulin 한국간호과학회 2022 Asian Nursing Research Vol.16 No.3
Purpose: The aim of this paper is to develop a scale for measuring the perinatal bereavement care competence of midwives and assess its psychometric properties. Methods: The Perinatal Bereavement Care Competence Scale was developed in four phases. (1) Item generation: 75 items were formulated based on a literature review and interviews with midwives. (2) Delphi expert consultation: 15 experts evaluated whether the items were clear/appropriate/relevant to the questionnaire dimensions, and the items were optimized. (3) Pilot test: The comprehensibility, acceptability, and time required to complete the questionnaire by midwives were assessed. (4) Evaluation of reliability and validity: The scale was validated by initial item analysis, exploratory and confirmatory factor analyses, and internal consistency reliability and testeretest reliability. Results: The final scale consisted of six dimensions and 25 items: maintaining belief (three items), knowing (four items), being with (six items), preserving dignity (four items), enabling (five items), and self-adjustment (three items). Exploratory factor analysis yielded a six-factor structure that was consistent with the theoretical framework and explained 70.8% of the total variance. Confirmatory factor analysis indicated a good fit for the six-factor model. Cronbach's a for the scale was 0.931, and the test eretest reliability coefficient was 0.968. Conclusion: The Perinatal Bereavement Care Competence Scale is a valid and reliable instrument for measuring the competence of midwives in caring for bereaved parents who have experienced perinatal loss.
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Kunzhi Xu,Feng Ding,Qing Li,Xiangang Xie,Lei Yang,Ying Li,Binbin Dong 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.5
Located within the centre of the Tethys Himalayas, the Weimei Formation of the Rongbu area in southern Tibet is a littoral-neritic sedimentary association composed of clastic rocks and a few shales. Petrologic characteristics and detrital component statistics indicate that sandstone types include lithic quartz sandstones, with the average content of quartz, feldspar and debris being 77%, 9% and 14%, respectively. The provenance of the Weimei Formation is a recycled orogeny, and the aforementioned sandstones generally have high SiO2 levels, low CaO, K2O and Na2O levels and wide ranges of CIA and CIW values. The primitive mantle-normalised trace element spider diagrams showed unstable content of some elements and losses of Ba, P, Sr, K, Ti and other elements in partial samples. Chondrite-normalised rare-earth element (REE) patterns indicate that the sandstones are characterised by an enrichment of LREE, significant fractionation of LREE and HREE and negative Eu anomalies. Further, ratios of Sm/Nd and Cr/Zr and discriminant diagrams (i.e., La/Yb versus ΣREE, ΣREE versus SiO2/Al2O3, La/Th versus Hf and function discrimination diagrams) reveal that sandstones from the Weimei Formation were derived from ancient quartzose sedimentary rocks and volcanic rocks of continental island arc. Many important parameters (i.e., La, Ce, Pb, Th, Hf, Zr, ΣREE, La/Yb, (La/Yb)N, ΣLREE/ΣHREE, Eu/Eu*, Rb/Sr and Zr/Hf) of samples and tectonic setting discriminant diagrams (i.e., Th versus Co versus Zr/10, La versus Th versus Sc, La versus Th and function discriminant diagrams) indicate that the tectonic setting of the Weimei Formation sandstones from the Tethys Himalayas has both characteristics of a passive margin and continental island arc. By comparing the detrital zircon U-Pb ages and Hf isotopic characteristics of the Weimei Formation with the strata whose provenances have been identified and analysing the weathering, petrography and geochemistry characteristics of Weimei Formation sandstones and the paleogeography conditions of the northern margin of the India craton within the Late Jurassic epoch, we inferred that Weimei Formation sandstones were mainly sourced from the Precambrian metamorphic rocks of the India craton, simultaneously, the sandstones also received minor sedimentary materials from earlier Tethys Himalaya strata whose provenances contained volcanic rocks of the nearby Gangdese volcanic belt. After experiencing weak to moderate weathering, denudation and long-distance transport, the sedimentary materials eventually migrated to the shelf and the top of the continental slope on the northern margin of the Indian continent, where the materials later participated in diagenesis.
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