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연구논문 : 제주지역 미세먼지의 장기변동 및 농도변화에 관한 국지기상 분석
박연희 ( Yeon Hee Park ),송상근 ( Sang Keun Song ),이수정 ( Soo Jeong Lee ),김석우 ( Suk Woo Kim ),한승범 ( Seung Bum Han ) 한국환경과학회 2016 한국환경과학회지 Vol.25 No.1
Long-term variations of PM_{10} and the characteristics of local meteorology related to its concentration changes were analyzed at 4 air quality sites (Ido-dong, Yeon-dong, Donghong-dong, and Gosan) in Jeju during two different periods, such as PI (2001-2006) and PII (2007-2013), over a 13-year period. Overall, the long-term trend of PM_{10} was very slightly downward during the whole study period, while the high PM_{10} concentrations in PII were observed more frequently than those in PI. The concentration variations of PM_{10} during the study period was clarified in correlation between PM_{10} and meteorological variables, e.g. the low (high) PM_{10} concentration with large (small) precipitation or high (low) radiation and in part high PM_{10} concentrations (especially, Donghong-dong and Gosan) with strong wind speed and the westerly/northwesterly winds. This was likely to be caused by the transport effect (from the polluted regions of China) rather than the contribution of local emission sources. The PM_{10} concentrations in “Asian dust” and “Haze” weather types were higher, whereas those in “Precipitation”, “Fog”, and “Thunder and Lighting” weather types were lower. The contribution of long-range transport to the observed PM_{10} levels in the urban center (Ido-dong, Yeon-dong, and Donghong-dong), if estimated by comparison to the data of the background site (Gosan), was found to explain about 80% (on average) of its input.
사망진단서(사체검안서) 상의 선행사인으로부터 사망통계의 원사인이 선정되는 비율 : 3개 대학병원에서 교부된 사망진단서를 중심으로
박우성,박석건,정철원,김우철,탁우택,김부연,서순원,김광환,서진숙,부유경 한국의료QA학회 2004 한국의료질향상학회지 Vol.11 No.1
Background : To exatnine the problems intolved in writing practice of death certificates, we cotnpated the determination of underlying cause of death for wital statistics using recorded underlying cause of death in issued death statistics. Methods : We collected 688 rnortality certificates issue in year of 2,000 from 3 university hospitals. And we also collected vital statistics from ministry of statistics. The causes of death were coded by experienced medical record wpecialists. And causes of death determined at ministry of statistics for national vita statistics were mapped to causes of death recorded at each death certificates. The rate that underlying causes of death for vital statistics were derived from underlying causes of death recorded at issued death certificaties sere analysed. Results : 64.5% of underlying cause of death for could be derived from underlying cause of death recorded at issued death certificates, 8.6% derived from intermediate cause of death, and 3.9% derived from direct cause of death. In 23% of cases, underlying cause of death could not be derived using issued death certificates. The rate that underlying cause of death for vital statistics could be derived from underlying cause of death recorded at death certificates was different between 3 university hospitals. Ane the rate was also different between death certificates and postmortem certificates. We classified the causes of death using 21 major categories. The rate was different between diseases or conditions tha caused death too. Conclusion : When we examined the correctness of death certificate writing practice using abpve methods, cortectness of writing could not be told as satisfactory. There was difference in correctness of writing between hospotals, between death certificates and postmortem certificates, and between diseases and conditions that caused death. With this results, we suggested some strategy to improve the correctness of death certificate writing practice.
우형택,문연화 대구효성가톨릭대학교 1998 연구논문집 Vol.58 No.2
With respect to the increasing importance of understanding our environmental concerns, this study was conducted to develop the questionnaire for the comprehensive and objective measurement of environmental concerns and test its reliability. The major research methods taken include the design of environmental questionnaire based on literature review and related theories, and the process of increasing the reliability of developed questionnaire through the repetition of reliability analysis. The total of 3 surveys were conducted and the total of 510 persons including diverse sample groups were questionnaired. The SAS PC+ package program was used in the reliability analysis of surveyed data. The first designed questionnaire consisted of 50 items including 25 items related to environmental pollution and 25 items related to nature conservation, reflecting various factors of environmental concerns. The result of the first reliability analysis showed that Cronbach-αfor the total was 0.75. To increase the reliability, items having low correlation with the total were eliminated, corrected, or revised. The reliability of redesigned questionnaire consisting of 46 items was significantly improved to the level of Cronbach-α0.88, the high reliability of measurement. In the second reliability analysis, 11 items were further revised and corrected to develop the questionnaire having the very high reliability. The reliability of the finalized questionnaire was further increased to the level of Cronbach-α0.92.
분편 인플루엔자백신(split influenza vaccine)의 임상효과 및 면역원성에 관한 연구
우흥정,김동림,정희진,천병철,이주연,안정배,김지희,박찬,신영규,김우주,김민자,박승철 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1
목적 : 아단위 인플루엔자 백신 접종 후 백신의 인플루엔자 예방효과, 인플루엔자 방어 항체형성, 인플루엔자 백신의 안전성을 조사하고자 하였다. 방법 : 총 571명을 대상으로 인플루엔자 백신 접종을 하였고, 이들 접종자에서 인플루엔자 양질환의 이환을 조사하여 인플루엔자 백신의 인플루엔자예방효과를 알아보았고, 백신의 접종 전 및 접종 4주 후 혈청에서 혈구응집억제물(Hemagglutination Inhibition : HAI) 항체 검사를 실시하여 백신의 방어항체생성을 조사하였고, 백신의 안전성을 알아보기 위해 백신접종 후 1주일 이내의 부작용을 조사하였다. 결과 :백신 접종군과 백신 비접종군에서 인플루엔자 양 질환의 이환을 조사한 결과 접종군 28.35%, 비접종군 35.88%으로 나왔으며, p 값이 0.001로 통계적으로 접종군에서 유의하게 낮았고, 인플루엔자 양 질환의 예방 효과는 20.97%를 보였다. 백신의 방어항체 형성의 평가를 위해 유럽의 인플루엔자 백신 허가 기준을 조사하였는데 B/Guangdong/5/94균주의 백신접종 후 항체가 40이상의 비율을 제외한 다른 기준은 모두 만족 시켰다. 부작용은 전체 조사자 521명중 149명(29%)으로 주로 접종 부위의 국소 부작용을 호소했고, 전신 부작용은 2% 내외였으며 특별히 심각한 부작용은 발견되지 않았다. 결론 : 분편 인플루엔자 백신은 인플루엔자양질환의 예방과 방어항체생성에 효과 있으며 안전한 것으로 사료된다. Background : The safety and effectiveness of influenza vaccine are well known in developed country. The influenza vaccination has been recommended as one of the tentative immunization schedule for indicated persons since 1997 in Korea. But there are still no available data about them, even though nearly 5 million doses of influenza vaccine were used in 1997-1998 season. So it is immediately needed to investigate the safety. efficacy and immunogenicity of influenza vaccine among Korean. Methods : We studied the clinical efficacy of influenza vaccine by monitoring Occurrence of influenza-like illness in influenza risk group(vaccination ; 300, non-vaccination; 215) from December in 1997 to March in 1998. We used the split quadrivalent influenza vaccine containing 15 microgram of hemagglutinin of A/Beijing/262/95(HlNl), A/Wuhan/359/95(H3N2), B/Mie/1/93 and B/Guangdong/5/94. Hemagglutination inhibition(HA1) antibody titers were determined before immunization and 1 months after vaccination And we evaluated adverse effect of influenza vaccination at 7 days after vaccination. Results : Influenza vaccination was associated with si@icant reductions in influenza-like spptoms(vaccination group; 28.35%, non-vaccination group, 35.88%, p=0.001). The preventive effect of influenza-like i3lne.s among influenza risk goup was 20.97%. And immunogenicity of influenza A and B exceeded all of the European licensure criteria for immunogenicity except postvaccination proportion of titers 240 of B/Guangdong/5/94 strain. And the adverse effects were mainly local injection site problem and no serious adverse effect was noted. Conclusion : Split influenza vaccine is safe, inmunogenic and eff'tive in influenza risk group in Korea.
추연규,탁한호,정민우 진주산업대학교 1999 산업과학기술연구소보 Vol.- No.6
In real world, most of plants has a nonlinearity and complexity. Thus it has a trouble for control with general control theory. Up to the present, we have controlled a nonlinear plants supposing that they was linear. But because we did so, many bad matters and errors was brought out in various area. To improve this problem this study tried to control a nonlinear plants with a nonlinear characteristic of artificial intelligence in real world. Industrial crane had a role as plant in this thesis. The critical load was measured and the optimal distance between crane and load and the angle of boom was found with neural networks. So data in table was approximated and generalized by an ability of function approximation in neural networks. The optimal angle of boom for random loads and the distance between crane and loads could be found with a inverse identification of neural networks.
Zn과 Cd의 처리가 GA와 Uniconazole 전처리된 메리골드 'Orange Boy'의 생육과 무기물 흡수에 미치는 영향
정성우,정연옥,허무룡,박중춘 경상대학교 농업생명과학연구원 2002 농업생명과학연구 Vol.36 No.4
메리골드(Tagetes patula L. 'Orange Boy')를 통해 오염지 식생복원과 동시에 양호한 식생경관 조성재료로서의 가능성을 알아보기 위해 본 실험을 수행하였다. 메리골드 'Orange Boy'에 있어서 Zn과 Cd 100+20㎎·L^-1 처리구에서는 GA_3 와 uniconazole은 생체량 및 Zn과 Cd의 축적에는 영향을 주지 않았다. 생장조절제 무처리구의 Zn과 Cd의 200+40㎎·L^-1 처리구에서 대조구의 20%로 건물량이 감소하였다. Zn과 Cd의 농도별 혼용처리에 따른 체내 무기성분 T-N, P, K, Ca, Mg함량은 뚜렷한 경향이 없었고, Zn의 축적은 뿌리와 잎에서 각각 1,227 및 903㎎·㎏^-1, Cd의 경우 줄기와 잎에서 각각 89.7 및 77.4㎎·kg^-1의 최대의 농도를 보였다. The use of plant-based systems to remediate contaminated soils has become an area of intense scientific study in recent years and it is apparent that plants which grow well in contaminated soils need to be identified and screened for use in phytoremediation technologies. This study was conducted to determine the effects of various combinations of Zn and Cd on growth and mineral concentrations of Tagetes patula L. 'Orange Boy'. With 100㎎·L^-1 Zn + 20㎎·L^-1 Cd, GA_3 and Uniconazole did not increase the plant biomass, and accumulation of Zn and Cd Total dry weight with 200㎎·L^-1 Zn and 40㎎·L^-1 Cd was 20% that of control. There was no significant to T-N, P, K, Ca, and Mg contents in leaf, stem, and root. The Zn contents of root and leaf were 1,227 and 903 ㎎·kg^-1, respectively. While the Cd was accumulated different site compared to Zn, the highest accumulation place were stem (74.4 ㎎·kg^-1) and leaf (89.7 ㎎·kg^-1).
인산화에 의한 RNA Polymerase II 역가 조절
김우연 中央大學校 遺傳工學硏究所 1990 遺傳工學硏究論集 Vol.3 No.1
Three subspecies of RNA polymerase II, designated II 0, II A, and II B, have been described in a variety of eukaryotic cells and shown to differ in the molecular weight of their largest subunit, designated II o, II a, and II b, respectively. The objectives of these studies were to define the structural relationship between these subspecies and to determine the functional significance of these differences. Molecular cloning of the gene encoding the largest RNA polymerase II subunit(II a) of mouse has revealed the 52 tandem repeats of the consensus sequence Try-Ser-Pro-Thr-Ser-Pro-Ser at the C-terminus. Multisite phosphorylation within the C-terminal domain of subunit II a give rise to RNA polymerase II 0. RNA polymerase II B arises from proteolytic cleavage of the C-terminal domain. Immunoblotting of cell extracts indicates that HeLa cells contain predominantly RNA polymerase II 0. To investigate the role of the C-terminal domain and the functional significance of its phosphorylation, subspecies of RNA polymerase II was purified and the ability of each subspecies to transcribe the major late promoter of adenovirus-2 was examined. Furthermore, the nature of the enzyme in the initiation complex and the elongating enzyme was determined by photoaffinity labeling. The results indicate that RNA polymerase II A is involved in the formation of the initiation complex, whereas RNA polymerase II 0 is the elongating enzyme. Current ideas concerning the role of the C-terminal domain in transcription and the effect of phosphorylation on the transcriptional activity of RNA polymerase II are discussed.
김연수,류지윤,김욱성,장우익,김한성 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2
Pulmonary sequestration is a rare congenital lung disease. It is classified as intrapulmonary sequestration, having own visceral pleura, and extrapulmoanry sequestration, not having own visceral pleura. We experienced two cases of intrapulmonary pulmonary sequestration. Two cases were developed in right lower lobe of lung. A 31 year old man had coughing, sputum, and febrile sensation for 2 months. He had antituberculosis medication because he was misdiagnosed as pulmonary tuberculucosis. The sequestrated lung was supplied by systemic artery originated from descending thoracic aorta. Another 58-year-old woman had symptoms of recurrent upper respiratory infection occurring over a seven-year period. We couldn't find aberrant artery form 2nd case. We performed lobectomy in two cases and patients were treated successfully without complication.
도시주부의 생활예절수행이 가족응집성 및 가정생활만족도에 미치는 영향
이정우,김연화 숙명여자대학교 출판부 2002 生活科學硏究誌 Vol.17 No.-
The purpose of this study was to explore the effect of performance of living proprieties on family cohesion and Family satisfaction, centering on house wives in the lives of Korean housewives. The results of this study were as follows: 1. The practice of life propriety was shown to be relatively high in house wives. The variables that affected this level were as follows: perceptiveness to the importance of propriety, self-esteem, perceptiveness to resource reasonableness. 2. Family cohesion and family satisfaction revealed a relatively high level. The variables affecting the family cohesion were self-esteem, perceptiveness to resource reasonableness, age, perceptiveness to the importance of propriety. The variables affecting the family satisfaction were self-esteem, perceptiveness to resource reasonableness, perceptiveness to health, gender-role attitudes, income, perceptiveness to the standard of living, fare orientedness. 3. The degree of the practice of life propriety significantly affected family cohesion and family satisfaction. 4. On the family satisfaction, the result showed the practice of life propriety were lower figures compared to the family cohesion. The important variables affecting the Family satisfaction were self-esteem, perceptiveness to resource resaonableness, perceptiveness to the importance of propriety, degree of the practice of life propriety. In addition, it was found that the most significant variable that influenced family satisfaction was family cohesion. Future research is needed to expand its focus on the practice of life propriety in the area of family resource management. More concrete and specialized family life education programs should be developed for the benefit of building healthy families.
이용연,서상훈,유화승,최우진,조정효,이연월,손창규,조종관 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1
Climical studies were carried out 83 cases of patients with colorectal cancer treated bv Hangamdan(抗癌丹) from January lth 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by colorectal cancer, by sex, showed that Male is more then Female, by age, showed that the numbber of fifties is majorith. 2. distribution of diagnostic stage, in descending order; stage Ⅲ(53%, top), stagew Ⅵ(45.8%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(83.3%) and combined treatment of westem and oriental therapy(92.1%)were boserved. The effects of the symptoms were as folows: diarrhea(37.3%),abdominal pain (25.3%), general body weakness(22.9%), nausea(20.5%) and etc. in orders. 4. Analysis of hematology attached by colorectal cancer, maintenance and increasing of WBC(89.9%), RBC(74.7%), Hgb(81.1%), Platelet(92.4%) were Observed. After taken Hangamdan, the satety of the liver and kidney were as follows; maintenance and decreasting of AST(85.9%), ALT(94.8%) , GTP(87.5%), Creatinine(90.9%) were observed. 5. of IL-12 and IFN-λ attached by colorectal cancer, increasing of IL-12(53.3%), IFN-λ(80%) were observedl. 6. Analysis of QOL attached by colorectal cancer, maintenance and improvement of combined treatment of western and oniental therapy(89.6%), traditional oriental therapy(83.3%) were observed. 7. Analysis of survival in patients with Ⅳ stage of colorectal cancer, above 7 months(18.4%), 12 months(65.8%). 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(83.3%) and maintenance and improvement of combined treatment of western and oriental therapy(80.5%) were observed. Analysis of tumor marker attached by colorectal cancer, maintenance and decreasing of CEA(78.8%) were boserved 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(83.3%), combined treatment of westem and oriental therapy(72.7%) were observed.