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이상진(Sang-Jin Lee),권이영(Yi-Young Kwon),조성원(Sung-Won Cho),권희숙(Hee-Suk Kwon),신우창(Woo-Chang Shin) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.4
본 연구에서는 한방이화주의 피부 생리기능 활성을 알아보기 위해 70% EtOH 추출물의 피부 미백, 주름 개선 및 항염증 효과를 조사하였다. HEE은 tyrosinase 활성 억제 및 tyrosine을 기질로 melanin이 형성되는 pathway에 관여하는 주요한 인자인 TRP-1과 TRP-2를 저해하는 작용 기전을 통해 피부 색소침착의 주요 원인 물질인 melanin 생합성을 농도 의존적으로 저해하는 것을 확인하였다. HEE은 피부진피 내 피부 탄력을 유지하는 elastin을 분해하는 효소인 elastase의 활성을 저해하였고, 피부의 keratinocyte가 생성분비하는 MMP-2와 MMP-9의 단백질 발현과 proteolytic 활성을 억제하여 노화에 따른 피부 주름 생성 억제할 수 있는 가능성을 확인하였다. 또한 세포 독성 없이 LPS에 의해 유도된 염증 반응을 50% 저해하는 HEE의 농도(IC50)는 24.9 μg/mL이며, 50 μg/mL 농도로 처리하였을 때 염증 반응 저해 효과가 70%로 높은 효과를 가지는 것을 확인하였다. 이상의 결과를 종합하면 HEE의 피부 미백, 주름 개선 및 항염증에 우수한 효과를 나타내고 있으므로 기능성 화장품의 주요한 소재로 이용 가치가 높을 것으로 사료된다. Extrinsic skin aging is characterized by the loss of skin tone and resilience, irregular pigmentation, and deep wrinkles. The aim of this study was to investigate the effects of Ehwa Makgeolli containing oriental herbs (Glycyrrhiza uralensis Fisch., Lycium chinense MILL., Morus alba L., and Saururus chinensis Baill) on skin whitening and wrinkling in human skin cells. We prepared Makgeolli extracts (HEE) with 70% ethanol. HEE significantly inhibited in vitro mushroom tyrosinase activity and reduced the cellular and secreted melanin content of mouse melanoma melanocytes (B16F1 cells). HEE down-regulated the protein expression of tyrosinase related protein (TRP)-1/-2, a key player in melanogenesis. Treatment with HEE in human keratinoctyes (HaCaT cells) inhibited the proteolytic activities of matrix metalloproteinase (MMP)-2/-9 in a dose-dependent manner and dramatically reduced the expression of MMP-2/-9. In addition, HEE attenuated lipopolysaccharide (LPS)- induced nitric oxide production in murine macrophages (RAW264.7 cells). These results indicate that HEE may be a great cosmeceutical ingredient for its whitening, anti-wrinkle, and anti-inflammatory effects.
Won, Hyun Kyu,Jeon, Hyon Sun,Han, Hee,Lee, Seung Jung,Jung, Byung Heon Institute of Forest Science 2017 Journal of Forest Science Vol.33 No.4
This study was aimed to analyze the increased forestry incomes by combining timber production and wood processing, which is one of 6th industrialization types in Korean forestry. The selected household has been engaged in forestry for two generations and they produce timber and associated wood products in their own facility. The wood products include dimension lumber, interior wood material, cutting board, and cube chips, the household also utilize logging and sawmill residues as well as seed and seedlings as by-products. Incomes and expenses that have been incurred on individual processes of the sequential timber production and wood processing were surveyed, and we analyzed the economic outcomes of entire business. The results of this study indicate that the gross income of the household is 122.3 million Korean won and the net income is 93.6 million Korean won. The net income of the household is approximately 2.8 times higher than the average net income of whole households in the forestry of Korea in 2016, which is approximately 4.3 times higher than that of households that have been particularly engaged in timber production over the country. We found that the 6th industrialization by combining the two sequential processes creates approximately 3.2 times as much added value compared to the case relying on timber production only.
이광원,임재환,이두희 충남대학교 농업과학연구소 1997 농업과학연구 Vol.24 No.2
The number of modernized green houses have been increased to produce high quality and high-pay off farm products. The unit investment costs per pyeong(3.3058㎡) for building a glass house was estimated at 449 thousand won. On the other hand, the unit prices for the PC house with iron frame and the vynil house with automatic control system were revealed 365 thousand won and 93 thousand won respectively. The main objective of the study was to identify the financial feasibility of the green house investment prevailed in rural area. At present, some farmers have selected the green house without any consideration of profitability of crops and accessibility of their farming practices and technology. For the soundness of green house cultivation and management, the indices of finacial efficiency for the modernized green houses were necessary. The decesion making criteria such as NPV(Net Present Value), IRR(Internal Rate of Return), B/C Ratio and Payback Period were analyzed for the individual high investment facilities considering the present farmer's technology and on-farm benefits and costs. The results of the feasibility analysis of green houses were as follows: 1. In case of 100% private burden of the investment costs, NPV revealed only positive value for the vinyl house with automatic system and IRR for the house was also estimated at more than 10% and B/C Ratio was amounted to more than 1.0. On the other hand, the other glass and PC houses showed negative NPV and unacceptable B/C ratio and IRR. 2. In case of the following terms and conditions as 50% Government subsidy, 20% loans and 30% farmers burden of the total investment cost, all the green houses showed acceptable IRR. B/C Ratio and NPV. 3. The financial feasibility of the glass house was acceptable in tomato cultivation rather than in cucumber cultivation. The payback periods of cucumber were represented as 8.9 years for glass house, 8.5 years for PC house and 4.1 years for vinyl house with automatic system respectively. In conclution, the glass and PC house cultivation of high value vegetables were only acceptable under the Government subsidy and loan systems from the view point of farmer's financial situations. On account of the unacceptable economic rate of return, the government subsidy and loan policy for glass house cultivation should be transfered to the vinyl and pc houses in the future.
염원희(Youm, Won-hee) 한국민속학회 2016 韓國民俗學 Vol.63 No.-
<삼풍백화점 괴담>은 사회적 참사(慘事)를 소재로 하는 도시전설 중 하나이다. 삼풍백화점 참사는 한국인이라면 누구나 기억하고 있는 일종의 집단기억이며, 이를 바탕으로 하는 도시전설은 ‘집단기억의 형상화로서의 이야기’라 할 수 있다. 도시전설은 허구의 이야기로서 참사와는 별개로 존재하지만, 당시의 참사가 이야기를 통해 회자됨으로써 사람들에게 사건의 참혹함을 지속적으로 상기시키는 역할을 한다. 또한 사건에 대한 대중의 감정이 드러나는 창구 역할을 하여 전승자가 감정을 해소할 수 있는 효과를 갖는다. 기존에 연구된 도시전설은 일본과의 영향관계가 부각되었으나 본고에서 다루는 <삼풍백화점 괴담>의 경우, 일본의 영향을 받은 면을 찾아보기 어려웠다. 공포의 대상, 정서와 서사구조, 죽음관 등에서 전통적 맥락이 드러난다는 점에서 한국적 도시전설의 일면을 확인할 수 있었다. One of the urban legends based on a social event is the one originating from the tragedy of the collapse of Sampung Department Store. The disaster is a kind of collective memory that many Koreans remember, and the urban legend based on it can be regarded as “a story that is the embodiment of collective memory.” An urban legend based on a social event exists separately from the incident; yet as the accident becomes the talk of the town through stories, it continuously reminds people of the cruelty of the incident. In addition, it acts as a window to reveal the public"s emotions about the event, and it has an emotional cathartic effect. While earlier researches on urban legends have focused on their relation to Japan, in the case of the urban legend based on the Sampung Department Store tragedy, which is the focus of this paper, it was difficult to find any aspects influenced by Japan. Some aspects of the Korean style of urban legends were investigated. For instance, it was found that the appearance of traditional figures, such as ancestor gods or the angel of death, is based on the ideas of folk religion. Also, traditional context was exposed in its narrative structure and its view of death.
측뇌실내 수막종 : 임상분석 및 수술접근법 Clinical Analysis and Surgical Approach
양희진,김동규,정희원,이현구,김현집,조병규,최길수,한대희 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.10
The authors present six cases of lateral ventricle meningiomas treated at Seoul National University Hospital between 1979 and 1991. These six cases of lateral ventricular meningiomas constitute 1.8 percent of all intracranial meningiomas and 16.7 percent of mass lesions of the lateral ventricle. The mean age was 29 years ranging from 11 to 50 years, younger than that or intracranial meningiomas with a statistical significance(p<0.01). Four of the patients were women and two were men. All cases were located in the trigonal area. The most common clinical symptoms and signs were related to increased intracranial pressure such as headache, nausea and vomiting. Based on the clinical presentation and radiological features(CT. MRI and angiography), correct preoperative diagnosis was possible in five cases. Gross total removal of the tumor was achieved in all cases. There was no operative mortality. A temporal gyrus approach was used in five cases with good surgical results. The benefits and drawbacks of each surgical approach for meningiomas of the lateral ventricle is discussed with review of pertinent literatures.
정신훈련 프로그램의 실시에 따른 체육수업 참여유형 비교연구
김원배,김정수,정청희,노희덕,홍준희 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.1
The purpose of this study was to identify the student participation styles in elementary school physical education classes. To identify the student participation styles, the factors such as subject, teacher, parents, the level of family economy and classroom environments were investigated. To achieve the purpose of this study was observed during 3 months in 1997. Educational ethnography was used in order to collect qualitative date. The subjects were 40 students on grade 4 in Chang Soe elementary school. Student participation styles were categorized six domains based on classroom teacher's observation and evaluation about them for 4 months. This styles included 'enthusiastic students', 'officious helpers', 'modifiers', 'ball girl-ball boys', 'timid paragons', and 'halfway students' Enthusiastic student was characterised by learning ability and attitude in his classroom, Officious helper by interference in other students in classes, Modifiers by the his tendency of exchange and execuse about the teacher-assigned-task, Ball girls-ball boys by yield their opportunity to participation in games and took peripherial position as by-hnaders, Timid paragons by work his task only when the teacher let him ordered and listen to teacher's explanation attentively, Halfway students by very bad learning attitude and made distribute the learning circumstances by their mischief. The result of this study were as follows;
베타-1, 3-글루칸 합성능이 손상된 SACCHAROMYCES CEREVISIAE 돌연변이주의 유전적 분석
이동원,박상원,진은희,정재훈,김진미,박희문 충남대학교 생물공학연구소 1996 생물공학연구지 Vol.4 No.-
A conditional lethal mutant of Saccharomyces cerevisiae, which can grow only on a osmotically remediable medium and is defective in β-1, 3-glucan synthase activity at nonpermissive temperature (37℃) was genetically analyzed. Two genes, BGS1 and BGS2, affecting in vitro activity of β-1,3-glucan synthase were identified. One gene, TOS1-1, affecting the osmotic stability of yeast cell was also identified. All three genes seemed to be unlinked each other. The defect in β-1,3-glucan synthase activity, however, seemed to be aggravated by the coexpression of tos1-1 and bgs1 mutation. Furthermore the results indicate that TOS1-1 can be a third gene involved in β-1,3-glucan synthesis in yeast.
김희남,송승기,정윤중,윤여권,김희원,조상원,심재환 한국안전학회 2003 한국안전학회지 Vol.18 No.2
The magnetic polishing is the useful method to finish some machinery fabrications by using magnetic power. This method is one of the precision techniques and has an aim for clean technology in the transportation of the pure gas in the clean pipes. The magnetic abrasive polishing method is not so common in the field of machine that it is not known to widely. There are rarely researcher in this field because of non-effectiveness of magnetic abrasive. Therefore, in this paper we deals with the development of the magnetic abrasive with the use of Ba-Ferrite. In this development, abrasive grain WA has been made by using the resin bond fabricated at low temperature. And magnetic abrasive powder was fabricated from the Ba-Ferrite which was crushed into 200 mesh. The XRD analysis result shows that only WA abrasive and Ba-Ferrite crystal peaks were detected, explaining that resin bond was not any more to contribute chemical reaction. From SEM analysis, we found that WA abrasive and Ba-Ferrite were strongly bonding with each other.
경연 대회를 통한 초ㆍ중고생의 창의력 신장 효과에 관한 연구
이희복,육근철,류해일,김현섭,김희수,박달원,유병환,김선효,김여상,서광수,변두원,서명석,배성효,박종석,심규철,이성희 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1
미래 사회를 대비하기 위한 개인의 개성을 존중과 창의적인 능력을 지닌 인간을 양성을 목적으로 충청남도 지역의 초 ㆍ 중고등학생들을 대상으로 한 창의력 경연대회가 공주대학교 과학교육연구소에서 개최되었다. 충청남도 초 ㆍ중 ㆍ 고등학생들을 대상으로 실시한 창의력 경연대회는 창조적 아이디어를 내어 스스로 문제를 해결해 나갈 수 있는 교육 프로그램을 제공하는 좋은 기회였음이 확인되었으나, 일부의 팀에서만 참신하고 재미있는 아이디어들이 제안되었다. 여학생의 참가자 수가 상당히 증가하였으며, 대체적으로 입상권의 학생들의 상당 부분이 여학생이라는 것이 특이할만하다. 학년이 올라감에 따라서 창의적인 아이디어를 내는 양이나 질에 있어서 뒤떨어지는 것으로 분석되었으며, 토론 학습의 적응력이 미흡하고 발표력 및 청취력에 있어서도 떨어지는 것으로 나타났다. 따라서 중 ㆍ고등학교의 학교교육에서도 학생들에게 프로젝트형 탐구학습 프로그램의 적용은 물론 토론식 수습을 통한 학생들의 사고의 전환의 기회를 제공해야 할 것으로 사료된다. The creativity competition was held to foster the creativity of elementary and secondary school students in the Institute of Science Education, Kongju national University. It was found that the creativity competition effected on the improvement of inventing creative ideas and problem solving activities. But, only some competitors participated in semifinal and final contests, presented original and interesting ideas. More female students participated in competition than last year. More female participants were awarded a prize than males. Totally, participants were defective in discussion and communication, and presentation and listening ideas. Increasing grades correlated inversely with creativity and originality. There is need of inquiry project teaming programs and presenting opportunities of conversion of thinking by discussing instructions in school