Korean ECM : Semantic and Pragmatic Factors

Stephen Wechsler,Yae Sheik Lee 언어과학회 1995 언어과학연구 Vol.12 No.-

Comparison of Alcohol Secondhand Effects among Korean and U.S. College Students

천성수,손애리,이상숙,Henry Wechsler,Easton A. Reid,Rubelyn Inot,Grace Percoheles,김미경 한국보건교육건강증진학회 2009 보건교육건강증진학회지 Vol.26 No.5

Objectives: To compare alcohol secondhand effects among US and Korean students. Methods: Nationally representative 4-year colleges of two countries were involved in this cross-national comparison study. Data from the 2001 U.S. College Alcohol Study and the 2003 Korean College Alcohol Study came from 120 colleges in 38 U.S. states and the District of Columbia and 60 colleges in Korea. Randomly selected 4-year college students from the U.S. (10,924) and Korea (2,385) participated in the study using self-reports of alcohol use and perceptions of drinking as assessed by College Alcohol Study questionnaires. Results: Korean students were tend to more likely to have being a victim of sexual assault or date rape, having to take care of drunken students and finding vomit in the hall or bathroom of residence, than US students, while US students were tend to more likely to have being insulted or humiliated, having a serious argument and quarrel, being pushed, hit, or assaulted, having study/sleep interrupted, and experiencing an unwanted sexual advance than Korean students. In general, US students were more likely to suffer interrelationship problems after drinking while Korean students were more likely to have physical and individual drinking related problems. Objectives: To compare alcohol secondhand effects among US and Korean students. Methods: Nationally representative 4-year colleges of two countries were involved in this cross-national comparison study. Data from the 2001 U.S. College Alcohol Study and the 2003 Korean College Alcohol Study came from 120 colleges in 38 U.S. states and the District of Columbia and 60 colleges in Korea. Randomly selected 4-year college students from the U.S. (10,924) and Korea (2,385) participated in the study using self-reports of alcohol use and perceptions of drinking as assessed by College Alcohol Study questionnaires. Results: Korean students were tend to more likely to have being a victim of sexual assault or date rape, having to take care of drunken students and finding vomit in the hall or bathroom of residence, than US students, while US students were tend to more likely to have being insulted or humiliated, having a serious argument and quarrel, being pushed, hit, or assaulted, having study/sleep interrupted, and experiencing an unwanted sexual advance than Korean students. In general, US students were more likely to suffer interrelationship problems after drinking while Korean students were more likely to have physical and individual drinking related problems.

일회성 다부위 신경융해술이 뇌성마비 아동의 치료에 미치는 효과

김혜경,김성우,Barbara Wechsler,김종태,권범선 대한재활의학회 2006 Annals of Rehabilitation Medicine Vol.30 No.5

Dupilumab Long-term Safety and Efficacy in Patients with Asthma: Liberty Asthma Traverse

( Hae Sim Park ),( Michael E. Wechsler ),( Linda B. Ford ),( Jorge F. Maspero ),( Ian D. Pavord ),( Yuji Tohda ),( David Langton ),( Christian Domingo ),( Alberto Papi ),( Arnaud Bourdin ),( Henrik Wa 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.0

Background Dupilumab, a fully human monocolonal antibody, blocks the shared receptor component for interleukin (IL) 4 and IL 13, key and central drivers of type 2 inflammation in multiple diseases. The efficacy and safety of dupilumab in asthma have been demonstrated up to 52 weeks in phase 2 and phase 3 studies. This open-label extension (OLE) study (NCT02134028) assessed long-term safety and efficacy of dupilumab in adult and adolescent patients who had completed a dupilumab asthma study (phase 2b DRI, phase 2 EXPEDITION, phase 3 QUEST, or phase 3 VENTURE). Methods Patients with moderate-to-severe or oral corticosteroid (OCS)-dependent severe asthma received add on subcutaneous dupilumab 300 mg every 2 weeks (q2w) up to 96 weeks. Treatment-emergent adverse events (TEAEs), annualized rate of severe asthma exacerbations (AER) during the treatment period, change from parent study baseline (PSBL) in forced expiratory volume in 1 second (FEV1), and biomarkers up to Week 96 were assessed. Results 2,282 patients were enrolled overall. Patient safety profile was consistent with the parent studies (Table). The low unadjusted AER and improvement in FEV1 observed in the parent studies were sustained during the OLE. Similar efficacy was seen in patients with elevated type 2 biomarkers from DRI/QUEST. By Week 96, blood eosinophils decreased to below-PSBL levels in patients from DRI/QUEST and were near-PSBL levels in patients from VENTURE; total IgE levels decreased by 82% (median percent change from PSBL). Conclusion Long-term use of dupilumab was well tolerated and showed sustained efficacy in asthma patients up to 96 weeks.

Cross-national comparison of perceptions to heavy episodic drinking and drinking behaviors among Korean and U.S. college students

Chun, Sung-Soo,Nelson, Toben F.,Reid, Easton A.,Wechsler, Henry The Korean Society for School Community Health Edu 2011 한국학교지역보건교육학회지 Vol.12 No.3

배경 및 목적 : 미국과한국양국의대학생의음주문제는심각한사회문제이며, 대학생의음주문제를예방하기 위한 다양한 노력들이 시도되고 있다. 본 연구는 미국과 한국대학생들의 음주와 폭음에 대한 인식 및 태도에 차이가 있는지를 비교 분석하기 위해 설계되었다. 방법 : 데이터는 2001년 미국의 하버드 보건대학원의 College Alcohol Study (CAS) 팀에서 미국의 120개 4년제 대학에서 10,904명에게서 조사한 원자료와 한국에서는2003년 삼육대학교 보건복지대학원의 Korean College Alcohol Study (KCAS) 팀에서 전국의 60개 4년제 대학의 2,385명의 원자료를 함께 통합하여 사용하였다. 이 자료의 특징은CAS에서 개발한설문지를 한국과 미 국양측에서 공동으로 사용하여 양 국가를 대표한 4년제 대학생의 표본을 대상으로 음주와 관련된 조사를 수행한 점이다. 결과 : 한국남학생들이 폭음할 기회가7.74배더많고 여학생의 경우는3.36배 더많다. 지난 한달동안 3회 이상 술 취한 경험율에서 한국 남학생들의 경험율이 34.3%로 미국의 20.4%보다 많고, 여학생의 경우도 24.6%로 미국 여학생의 11.1%보다 현저히 더 많다. 한국 대학생들의 폭음자 비율이 미국 대학생들의 폭음자 비율보다 많은 것과같이, 한국 대학생들이 미국의 대학생들 보다 폭음이 안전한 것으로 인식하고 있으며, 음주에있어서도더욱허용적인태도를가지고있다. 한국남학생의78.4%와 여학생의67.3%가 폭음 이상의 량을 안전하다고 인식하고 있다(미국은 남학생은 50.3%, 여학생은 34.1%). 폭음에 해당하는 음주량(남자는5잔 이상, 여자는4잔 이상)을안전하다고인식하는정도에서한국의대학생들이미국의대학생들에 비해서 남학생은 4.06배, 여학생이 3,96배 더 높다. 결론 : 한국 학생들 중에서도 음주의 량이 더 많은 학생들이 다른 학생들보다 음주와 술 취함과 폭음에 관하여 더욱 허용적이고, 안전한 음주에 대해 더욱 둔감한 태도와 신념을 보이고 있다.

The Incidence of Perioperative Stroke: Estimate Using State and National Databases and Systematic Review

Rami Al-Hader,Khalid Al-Robaidi,Tudor Jovin,Ashutosh Jadhav,Lawrence R. Wechsler,Parthasarathy D. Thirumala 대한뇌졸중학회 2019 Journal of stroke Vol.21 No.3

Background and Purpose Perioperative stroke remains a devastating complication after surgical procedures, due to hemodynamic and inflammatory changes that increase the risk of strokes within 30 days following surgery. We aimed to assess the incidence of perioperative strokes in patients undergoing various surgical procedures and reach a national estimate. Methods A retrospective cohort study was conducted using California State Inpatient Databases, State Emergency Department Databases, State Ambulatory Surgery and Services Databases, and the National Inpatient Sample (NIS) during the period 2008 to 2011 from the Healthcare Cost and Utilization Project. A systematic review was conducted using PubMed, Embase, and Web of Science databases to obtain published articles that reported the incidence of perioperative stroke in various surgical procedures. Results Analysis of 3,694,410 surgical encounters from the state of California (mean±standard deviation age: 52.4±21.1 years) yielded an overall rate of perioperative stroke of 0.32% (n=11,759). The incidence of perioperative strokes was highest following neurological (1.25%), vascular (1.07%), and cardiac (0.98%) surgeries. The NIS database contained a total of 48,672,974 weighted hospitalizations and yielded a rate of perioperative stroke of 0.42% (n=204,549). The systematic review completed yielded 187 articles, which had an overall sample size of 184,922 and an incidence of perioperative stroke ranging from 0% to 13.86%. It is estimated that in any given year, there would be approximately 40,000 to 55,000 (0.33% to 0.46%) perioperative strokes nationally. Conclusions Our findings support further strategies to identify and stratify patients undergoing surgical procedures with a high incidence of perioperative strokes to improve patient counseling and a future potential treatment plan.

13. BIOLOGICAL TECHNOLOGY OF THE TREATMENT OF LEACHATE FROM SANITARY LANDFILLS

P . S . Bull,J . V . Evans,R . M . Wechsler,K . J . Cleland 大韓環境工學會 1983 대한환경공학회지 Vol.5 No.2

Cross-national comparison of perceptions to heavy episodic drinking and drinking behaviors among Korean and U.S. college students

Sungsoo Chun,Toben F. Nelson,Easton A. Reid,Henry Wechsler 한국학교・지역보건교육학회 2011 한국학교지역보건교육학회지 Vol.12 No.3

A Comparison of Alcohol Secondhand Effects among Korean and U.S. College Students

Chun, Sung-Soo,Sohn, Ae-Ree,Reid, Easton A.,Inot, Rubelyn,Kim, Mi-Kyung,Percoheles, Grace,Lee, Sang-Sook,Wechsler, Henry Korean Society for Health Education and Promotion 2009 보건교육건강증진학회지 Vol.26 No.5

목적: 이 연구는 한국과 미국대학생의 음주로 인한 간접피해수준을 상대적으로 비교하기 위해 설계되었다. 방법: 하버드대학교의 대학생음주연구(CAS)의 2001년도의 원자료 10,924명의 데이터와 한국대학생음주연구(KCAS)의 2003년도의 원자료 2,385명의 데이터를 하나의 파일에 함께 넣어서 분석하였다. 조사도구는 CAS의 대학생용 조사설문지를 사용하였으며, 한국의 주종과 량과 관련하여서는 표준잔과 량을 기준으로 적용하였다. 지난 한 달 동안의 음주하였다고 한 학생의 알코올관련문제 및 간접피해의 정도를 비교하였으며, 연령과 음주빈도 와 음주량 통제하여 로지스틱회귀분석의 결과로 제시하였다. 결과: 한국대학생들이 술 취한 동료를 돌봄, 성적인 폭행, 데이트 강간, 구토물들을 발견하는 것 등의 간접피해를 많이 받는 반면에 미국대학생들은 모욕을 당함, 심하게 다툼, 밀침을 당함, 학업에 방해를 받음, 폭행을 당함, 원치 않은 섹스를 함 등의 간접피해를 더 많이 겪고 있다. 결론: 미국대학생들은 상호관계에 의한 간접피해를 많이 느끼는데 비해서, 한국대학생들은 개인적이고 신체적인 간접피해를 더 많이 느끼고 있다. Objectives: To compare alcohol secondhand effects among US and Korean students. Methods: Nationally representative 4-year colleges of two countries were involved in this cross-national comparison study. Data from the 2001 U.S. College Alcohol Study and the 2003 Korean College Alcohol Study came from 120 colleges in 38 U.S. states and the District of Columbia and 60 colleges in Korea. Randomly selected 4-year college students from the U.S. (10,924) and Korea (2,385) participated in the study using self-reports of alcohol use and perceptions of drinking as assessed by College Alcohol Study questionnaires. Results: Korean students were tend to more likely to have being a victim of sexual assault or date rape, having to take care of drunken students and finding vomit in the hall or bathroom of residence, than US students, while US students were tend to more likely to have being insulted or humiliated, having a serious argument and quarrel, being pushed, hit, or assaulted, having study/sleep interrupted, and experiencing an unwanted sexual advance than Korean students. Conclusion: In general, US students were more likely to suffer interrelationship problems after drinking while Korean students were more likely to have physical and individual drinking related problems.

Perioperative Stroke, In-Hospital Mortality, and Postoperative Morbidity Following Transcatheter Aortic Valve Implantation: A Nationwide Study

Parthasarathy Thirumala,Felix D. Nguyen,Amol Mehta,John Schindler,Suresh Mulukutla,Vinodh Jeevanantham,Lawrence Wechsler,Thomas Gleason 대한신경과학회 2017 Journal of Clinical Neurology Vol.13 No.4

Background and Purpose Perioperative stroke is a significant complication of transcatheter aortic valve implantation (TAVI). This study aimed to quantify perioperative stroke as an independent risk factor for in-hospital mortality and postoperative morbidity in patients receiving TAVI. Methods A retrospective cohort study was conducted using the National Inpatient Sample. Patients undergoing TAVI during 2012 and 2013 were identified using diagnostic codes of International Classification of Diseases, ninth revision. Univariate and multivariate analyses were performed using patient demographics and comorbidities to identify predictors of mortality and morbidity, defined by a length of stay of >14 days and/or discharge to a place other than home. Results Data were obtained from 7,556 patients undergoing TAVI during 2012 and 2013. The incidence rates of mortality and morbidity were 4.57 and 71.12%, respectively. Perioperative stroke was an independent risk factor for mortality [odds ratio (OR)=3.182, 95% confidence interval (CI)=1.530–6.618, p=0.002], as were infection (OR=17.899, 95% CI=9.876–32.440, p< 0.001) and pericardial tamponade (OR=7.272, 95% CI=2.874–18.402, p<0.001). Stroke also predicted morbidity (OR=5.223, 95% CI=2.005–13.608, p=0.001), which was also associated with age, being female, being Asian, moderate and high Van Walraven scores (VWR), and infection. Conclusions In conclusion, perioperative stroke was found to be independently associated with in-hospital mortality and postoperative morbidity, as are age and high VWR. Our findings support the use of further preoperative, intraoperative, and postoperative management strategies during TAVI.