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Sizing Efficiency of AKD in Causticizing Calcium Carbonate Filled Paper
Wang, Jian,Liu, Ling,Xu, Yong-Jian Korea Technical Association of the Pulp and Paper 2014 펄프.종이技術 Vol.46 No.2
Causticizing calcium carbonate (CCC) is produced as a by-product in the causticization step of the kraft pulping process. It is often calcined in a rotary lime kiln after being dewatered and reused in the causticizing process. But for the China mill, the conventional recycled way is difficult because the CCC is mainly obtained from non-wood pulping materials, which higher silicon content led to serious silicon obstacle. So it is often discarded as solid waste or used in landfill after dewatering and secondary pollution is brought. In order to prevent its secondary pollution, recent years, the CCC is used as a filler in China papermaking industry. In mill trials, the CCC can be used to replace an amount of precipitated calcium carbonate (PCC). Unfortunately, the application scope and dosage of CCC have been limited due to its lower sizing efficiency than PCC. In this study, the reason for the lower sizing efficiency of alkyl ketene dimer (AKD) when CCC was used as a filler was investigated. The results showed that the materials in green liquid, such as insoluble matter in green liquid, silicon and metal ions, were a little influence on the sizing efficiency of AKD. The higher BET and BJH pore volume of the CCC were the main reason for lower sizing efficiency of AKD when it was used as filler.
GEOMETRIC QUANTIZATION OF ODD DIMENSIONAL SPINc MANIFOLDS
Jian Wang,Yong Wang 대한수학회 2012 대한수학회보 Vol.49 No.2
We prove a Guillemin-Sternberg geometric quantization formula for circle action on odd dimensional $spin^c$-manifolds. We prove two Kostant type formulas in this case. As a corollary, we get a cutting formula for the odd spinc quantization.
Macrophage-secreted Exosomes Delivering miRNA-21 Inhibitor can Regulate BGC-823 Cell Proliferation
Wang, Jian-Jun,Wang, Ze-You,Chen, Rui,Xiong, Jing,Yao, Yong-Liang,Wu, Jian-Hong,Li, Guang-Xin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10
Exosomes, membranous nanovesicles, naturally carry bio-macromolecules or miRNA and play impoetant roles in tumor pathogenesis. Here, we showed that macrophages cell-derived exosomes can function as vehicles to deliver exogenous miR-21 inhibitor into BGC-823 gastric cancer cells. Exosomes loaded with miR-21inhibitor significantly increased miR-21 levels in BGC-823, but miR-21inhibitor loaded in exosomes exerted an opposite effect. miRNA transfected with exosomes had less cellular toxicity to host cells compared to conventional transfection methods. The miR-21inhibitor loaded exosomes promoted the migration ability and reduced apoptosis of BGC-823 gastric cancer cells. These observations indicate that miR-21 acts as a tumor promoter by targeting the PDCD4 gene and preventing apoptosis of gastric cancer cells through inhibition of PDCD4 expression. Furthermore, exosome -mediated miR-21 inhibitor delivery resulted in functionally more efficient inhibition and less cellular toxicity compared to conventional transfection methods. Similar approaches could be useful in modification of target biomolecules in vitro and in vivo. These findings contribute to our understanding of the functions of miR-21 and exosomes as a carrier for therapy of gastric cancer.
GEOMETRIC QUANTIZATION OF ODD DIMENSIONAL SPIN<sup>c</sup> MANIFOLDS
Wang, Jian,Wang, Yong Korean Mathematical Society 2012 대한수학회보 Vol.49 No.2
We prove a Guillemin-Sternberg geometric quantization formula for circle action on odd dimensional $spin^c$-manifolds. We prove two Kostant type formulas in this case. As a corollary, we get a cutting formula for the odd spinc quantization.
Image post-processed approaches for cavitating flow in orifice plate
Yong Wang,Suguo Zhuang,Houlin Liu,Zhenjiang Zhao,Matevž Dular,Jian Wang 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.7
A comprehensive investigation on cavitating flow and cavitation-induced erosion was performed experimentally in an orifice plate system. Three image post-processed approaches were applied to analyze the test data, in order to obtain the cavitation characteristics. The cavitating flow pattern was studied by high speed images. In one cavitation developing period, there could be three distinct cavitation clouds, whereas the second one is not fully developed. The first image post-processing approach was applied to obtain the mean value and standard deviation distribution, which indicate the erosion area may cover almost all the cavitation developing route and the most vulnerable erosion area locates near the cavitation collapse site. It is coincides with the erosion tests analyzed through the pit-count algorithm approach. The cavitation circulation frequency was invested via PSD analysis approach. It shows that the frequency linearly decreasing with decreasing cavitation number. Additionally, the cavitation intensity effect on cavitation erosion was quantitatively studied based. It is found that the damages are strongly enhanced when increasing the flow velocity. Moreover, the growth rate of eroded pits number is actually stepwise instead of linear (similar to our previous work in a venturi tube), which supports the idea that the cloud cavitation collapse is the primary reason for erosion. The present approaches applied here shows good potential ability of investigating cavitating flows and can be utilized for other apparatus.
Huan Wang,Yu Zou,Zhong Zhang,Kai-Yuan Wang,Huan An,Chang-Yong Zhan,Jun Wang,Jian-Chun Wu 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.8
The migration properties of uranium vacancies and interstitials in zirconium-doped uranium dioxide are studied by using density functional theory (DFT) and the climbing-image nudge elastic band (CI-NEB) method. The strong correlations among uranium $5f$ electrons were described by using a spherically averaged Hubbard parameter. In the model, the zirconium atoms are introduced by replacing the uranium atoms at the nearest and the next nearest neighbor sites along the diffusion path of uranium defects. The doping with zirconium obviously reduces the migration barriers for defects in uranium dioxide. The effect of doping with zirconium on the diffusion of uranium defects decreases with increasing distance between the zirconium dopant and the uranium defects. Further, we investigated the lattice distortion and the electron transfer associated with the migration of uranium defects, and we analyzed the physical origin of the reduction in the migration barriers caused by zirconium doping.
Xin, Yong,Wang, Jia-Yang,Li, Liang,Tang, Tian-You,Liu, Gui-Hong,Wang, Jian-She,Xu, Yu-Mei,Chen, Yong,Zhang, Long-Zhen Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3
Objective: To make sure the feasibility with $^{18F}FDG$ PET/CT to guided dynamic intensity-modulated radiation therapy (IMRT) for nasopharyngeal carcinoma patients, by dosimetric verification before treatment. Methods: Chose 11 patients in III~IVA nasopharyngeal carcinoma treated with functional image-guided IMRT and absolute and relative dosimetric verification by Varian 23EX LA, ionization chamber, 2DICA of I'mRT Matrixx and IBA detachable phantom. Drawing outline and making treatment plan were by different imaging techniques (CT and $^{18F}FDG$ PET/CT). The dose distributions of the various regional were realized by SMART. Results: The absolute mean errors of interest area were $2.39%{\pm}0.66$ using 0.6cc ice chamber. Results using DTA method, the average relative dose measurements within our protocol (3%, 3 mm) were 87.64% at 300 MU/min in all filed. Conclusions: Dosimetric verification before IMRT is obligatory and necessary. Ionization chamber and 2DICA of I'mRT Matrixx was the effective dosimetric verification tool for primary focal hyper metabolism in functional image-guided dynamic IMRT for nasopharyngeal carcinoma. Our preliminary evidence indicates that functional image-guided dynamic IMRT is feasible.
MiR-421 Regulates Apoptosis of BGC-823 Gastric Cancer Cells by Targeting Caspase-3
Wu, Jian-Hong,Yao, Yong-Liang,Gu, Tao,Wang, Ze-You,Pu, Xiong-Yong,Sun, Wang-Wei,Zhang, Xian,Jiang, Yi-Biao,Wang, Jian-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13
MicroRNAs might act as oncogenes or tumor suppressors in cancer. Recent studies have shown that miR-421 is up-regulated in human gastric cancer. Here, we found that miR-421 was over-expressed in gastric cancer tissues and cell lines. Bioinformatics analysis predicted that the caspase-3 gene was a target of miR-421. Caspase-3 was negatively regulated by miR-421 at the post-transcriptional level. Bax and Bcl-2 were also regulated by miR-421. Moreover, tumor necrosis factor receptor-I and -II, death receptors in the apoptosis pathway, were up-regulated by miR-421. The over-expression of miR-421 promoted gastric cancer cell growth and inhibited apoptosis of the BGC-823 gastric cancer cell line. These observations indicate that miR-421 acts as a tumor promoter by targeting the caspase-3 gene and preventing apoptosis of gastric cancer cells through inhibition of caspase-3 expression. These findings contribute to our understanding of the functions of miR-421 in gastric cancer.
Wide-Tunable Mid Infrared Intra-cavity Optical Parametric Oscillator Based on Multi-period MgO:PPLN
Xiao-Chan Wang,Yu-Heng Wang,Hao Zheng,Hong-Zhi Liu,Yong-Ji Yu,Zi-Jian Wang 한국광학회 2021 Current Optics and Photonics Vol.5 No.1
This paper reports a tunable diode-pumped folded intracavity Q-switched singly resonant optical parametric oscillator based on multi-period MgO:PPLN. A wide tuning mid-infrared parametric lightfrom 2.78 μm to 4.17 μm was obtained in real time by changing the poled periods and temperatures. The maximum output power of 1.89 W at 3.2 μm, 1.53 W at 3.5 μm, 0.87 W at 3.8 μm and 0.486 W at 4.1 μm were achieved. The highest optical-optical conversion efficiency was 7.89%. During experiments, a range tunable output of 2.78–4.17 μm in the mid-infrared range was achieved.