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- 저자 : Vrinda (검색결과 5 건)
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Vrinda Saxena,Arghya Pal 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.4
Transcranial direct current stimulation (tDCS) is a form of novel brain stimulating method that has attracted interest owing to its relative inexpensiveness and ease of administration. It has been evaluated in many studies for its effectiveness in improving cognitive symptoms in Alzheimer’s disease (AD). However, our understanding regarding its efficacy and the most effective way of administering tDCS (in terms of lead placement to achieve response and prevent harmful consequences) is still evolving. The current meta-analysis was conducted to resolve the above issues. A search using appropriate keywords and medical subject headings was conducted on PubMed, Scopus and DOAJ database. Studies were analysed on pre-defined inclusion and exclusion criteria. Finally 11 studies were included for quantitative analysis from 1,021 obtained from initial search. All the studies included were methodologically of high quality, though an asymmetrical funnel plot raised the possibility of publication bias. tDCS was found to significantly improve the scores on cognition as compared to sham. Anodal tDCS was found to be significantly beneficial in this regards, whereas cathodal and dual stimulation were not. There were no significant difference in the number of drop-outs and adverse reaction in tDCS and sham group. The quality of evidence that we have reviewed in this study is robust. tDCS, particularly anodal tDCS is an effective treatment modality in AD. It is well tolerated in patients with AD. However, further studies are warranted to probe the role of tDCS in other domains of AD.
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Intrarater and interrater reliability of pulse examination in traditional Indian Ayurvedic medicine
Vrinda Kurande,Rasmus Waagepetersen,Egon Toft,Ramjee Prasad 한국한의학연구원 2013 Integrative Medicine Research Vol.2 No.3
Background: In Ayurveda, pulse examination (nadipariksha) is an important tool to assess the status of three doshas: vata, pitta, and kapha. Long historical use has been seen as a documentation of its efficacy; however, there is a lack of a quantitative measure of the reliability of the pulse examination method. The objective of this study was to test the intrarater and interrater reliability of pulse examination in Ayurveda. Methods: Fifteen registered Ayurvedic doctors with 3–15 years of experience examined the pulse of 20 healthy volunteers twice, for a total of 600 examinations. The examinations were performed blind and in a random order. Only the current status of dosha-specific methods of pulse examination were considered. Cohen's weighted κ statistic was used as a measure of intrarater and interrater reliability, and a hypothesis of homogeneous diagnosis (random rating) was tested. Following this, we tested whether proportions of ratings were equal between doctors. Results: According to the Landis and Koch scale, the level of reliability ranged from poor to moderate. It was observed that the doctors more frequently diagnosed a combination of two doshas than a single dosha. The κ values were generally larger for experienced doctors (p = 0.04). Conclusion: Experience and proper training have important roles in pulse examination.
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Vrinda Goel,Uttam Kumar Mandal 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.4
On the basis of the water-loving nature of Polyaniline (PANI), super hydrophilic polysulfone (PS) ultrafiltration membranes were prepared via in-situ polymerization of aniline on the surface of the membrane. Growing polyaniline in-situ leads to permeability enhancement of the ultrafiltration membrane. Surface-attenuated total reflection Fourier transform infrared spectroscopy, Atomic force microscopy, Scanning electron microscopy and energy dispersive X-spectroscopy and water contact angle demonstrated the successful attachment of PANI on PS membrane surface. Modified membranes containing increased amount of PANI were compared to the unmodified PS membrane to estimate the change in membrane performance, hydrophilicity and anti-fouling properties. PANI modified membranes showed higher water fluxes in comparison to unmodified membranes, while protein rejection was almost similar in both PANI modified and unmodified PS membranes. Atomic force microscopy and contact angle measurements confirmed increased membrane surface hydrophilicity with increasing PANI content. Fouling study and flux recovery experiments revealed that modified membranes exhibit higher flux recovery ratio (65%) and more stability to strong cleaning agents.
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Variational Bayesian Inference Based Image Inpainting using Gamma Distribution Prior
Rohit Sain,Vikas Mittal,Vrinda Gupta 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.12
Variational Bayesian (VB) inference is the latest iterative method for prediction of data in machine learning. It provides the solution for intractable integration in Bayesian methodology. In this paper, a simple VB linear regression is applied for prediction of the damaged pixels in an image. Bayesian linear regression model is used for prediction of the pixels. For this neighbor pixels are used as training data to generate the parameters of the prediction function. Now using this prediction function, damaged pixels are predicted and incorporated into the image. Proposed method is linear while image is a non-linear object, generally. Hence, for linearity, a small image window size is used to avoid the nonlinearities in image.
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