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Victor N. Vasilets,박기동,Valentina A. Surguchenko,Anna S. Ponomareva,Eugene A. Nemetz,Victor I. Sevastianov,배진우 한국고분자학회 2015 Macromolecular Research Vol.23 No.2
Adhesion and proliferation of NIH/3Т3 mouse fibroblasts on the surfaces of bacterial copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and its mixture with poly(ethylene glycol) with differing crystallinity, surfaceenergy, and mean roughness was investigated. The surface mean roughness of all films on both sides, at the air interfaceand at the glass interface, measured by atomic force microscopy, was higher (from 17.0±1.4 nm to 290.8±7.0 nm)than that of the tissue culture polystyrene control (9.5±0.6 nm). The structure, surface energy, and chemical compositionof bacterial films were studied by differential scanning calorimetry, contact angle measurements, and Fouriertransform infrared (FTIR) spectroscopy. After 48 h, cell proliferation on all surfaces was significantly less than onthe control substrate; however, after 72 and 96 h, cell proliferation was comparable with control on some surfaceswith sufficient roughness. Addition of poly(ethylene glycol) resulted in an increase of adhesion and the metabolicactivity of the cells, even for relatively smooth surfaces. The complex correlation of cell metabolic activity with surfaceenergy and crystallinity for “rough” (mean roughness >100 nm) and “smooth” (mean roughness < 100 nm) surfacesis discussed.
Ayowole Victor Atere,Victor Olusegun Oyetayo,Felix Akinsola Akinyosoye 한국식품보건융합학회 2022 식품보건융합연구 (KJFHC) Vol.8 No.6
Hypercholesterolaemia is one of the risk factors of coronary health in humans; hence this research was to investigate the effect of Parkia biglobosa seeds fermented with Lactobacillus plantarum on the cardiac risk factors of diet-induced hypercholesterolaemic Wistar rats. Hypercholesterolaemia in rats were experimentally induced and the hypercholesterolaemic Wistar rats were treated with iru samples. The total cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), liver biomarkers and cardiac risks factors were determined after inducement and treatment with iru. Fourteen (14)-days after inducement, the rats in the group induced had the highest weight of 112.40 g while the control group had 94.30 g. The total cholesterol (TC) in the induced group was 100.80 mg/dl while the control had 51.40 mg/dl, triglyceride (TG) in the induced group was 111.75 mg/dl while the control group had 68.45 mg/dl. After 28 days of treatment, the group treated with fermented samples showed a reduction in the TC (100.80 to 56.99 mg/dl), Triglyceride (111.75 to 32.53 mg/dl), LDL (49.48 to 6.65 mg/dl), cardiac risk ratio (3.36 to 1.28), atherogenic coefficient (3.13-0.29) and atherogenic index (0.57 to 0.11). The result from this study reveals that fermented Parkia biglobosa sample reduced the cardiac risk of rats significantly.
Kulagin, Victor V,Cherepenin, Vladimir A,Gulyaev, Yuri V,Kornienko, Vladimir N,Pae, Ki Hong,Valuev, Victor V,Lee, Jongmin,Suk, Hyyong Published by the American Physical Society through 2009 Physical review. E, Statistical, nonlinear, and so Vol.80 No.1
<P>For controllable generation of an isolated attosecond relativistic electron bunch [relativistic electron mirror (REM)] with nearly solid-state density, we proposed [V. V. Kulagin, Phys. Rev. Lett. 99, 124801 (2007)] to use a solid nanofilm illuminated normally by an ultraintense femtosecond laser pulse having a sharp rising edge (nonadiabatic laser pulse). In this paper, the REM characteristics are investigated in a regular way for a wide range of parameters. With the help of two-dimensional (2D) particle-in-cell (PIC) simulations, it is shown that, in spite of Coulomb forces, all of the electrons in the laser spot can be synchronously accelerated to ultrarelativistic velocities by the first half-cycle of the field, which has large enough amplitude. For the process of the REM generation, we also verify a self-consistent one-dimensional theory, which we developed earlier (cited above) and which takes into account Coulomb forces, radiation of the electrons, and laser amplitude depletion. This theory shows a good agreement with the results of the 2D PIC simulations. Finally, the scaling of the REM dynamical parameters with the field amplitude and the nanofilm thickness is analyzed.</P>
Ayowole Victor Atere,Ayodeji Adedeji,Afolabi Clement Akinmoladun,Victor Olusegun Oyetayo,Felix Akinsola Akinyosoye 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.2
Hypercholesterolaemia is one of the risk factors in coronary heart disease. Hence, this research was designed to investigate the effect of iru on cholesterol levels in hypercholesterolaemic rats. The fermented condiment iru was produced naturally and with starter cultures of Lactobacillus plantarum, Bacillus subtilis, and Leuconostoc sp.. The hypercholesterolaemic rats were fed a diet supplemented with iru for 28 days, and total cholesterol, triglyceride (TG), high density lipoproteins (HDL), and low density lipoproteins (LDL) were determined before and after feeding. Cholesterol levels in hypercholesterolaemic rats (100.80 mg/dL) were reduced to 56.99∼80.21 ㎎/dL after feeding with iru supplementation while rats not placed on the iru diet had cholesterol levels of 119 ㎎/dL. There were also significant reductions (P<0.05) in serum TG (78.77∼32.57 ㎎/dL) and LDL (28.43∼6.63 ㎎/dL) levels in rats fed the iru diet compared with the control (63.36 ㎎/dL). Higher and significantly different (P<0.05) HDL was found in rats fed with iru fermented with L. plantarum (44.01 ㎎/dL) while the least was found in the untreated group (28.93 ㎎/dL). The results from this study suggest that supplementing the diet with iru obtained by the fermentation of Parkia biglobosa seeds may significantly reduce cholesterol level in the blood stream.
ATERE, Ayowole Victor,OYETAYO, Victor Olusegun,AKINYOSOYE, Felix Akinsola Korea FoodHealth Convergence Association 2022 융합경영연구 Vol.8 No.6
Hypercholesterolaemia is one of the risk factors of coronary health in humans; hence this research was to investigate the effect of Parkia biglobosa seeds fermented with Lactobacillus plantarum on the cardiac risk factors of diet-induced hypercholesterolaemic Wistar rats. Hypercholesterolaemia in rats were experimentally induced and the hypercholesterolaemic Wistar rats were treated with iru samples. The total cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), liver biomarkers and cardiac risks factors were determined after inducement and treatment with iru. Fourteen (14)-days after inducement, the rats in the group induced had the highest weight of 112.40 g while the control group had 94.30 g. The total cholesterol (TC) in the induced group was 100.80 mg/dl while the control had 51.40 mg/dl, triglyceride (TG) in the induced group was 111.75 mg/dl while the control group had 68.45 mg/dl. After 28 days of treatment, the group treated with fermented samples showed a reduction in the TC (100.80 to 56.99 mg/dl), Triglyceride (111.75 to 32.53 mg/dl), LDL (49.48 to 6.65 mg/dl), cardiac risk ratio (3.36 to 1.28), atherogenic coefficient (3.13-0.29) and atherogenic index (0.57 to 0.11). The result from this study reveals that fermented Parkia biglobosa sample reduced the cardiac risk of rats significantly.
Optogenetics: Solving the Enigma of Sleep
Victor James,Jae Meen Lee,Tae Kim 대한수면학회 2018 sleep medicine research Vol.9 No.1
Sleep is a crucial and evolutionarily conserved phenomenon, but the mechanisms that control sleep-wake behavior and underlie sleep disorders are not yet fully understood. One major challenge for sleep research was the lack of technology that allows for cell-type- and circuit-specific investigation of neurons and neural circuitry. A decade ago, a novel methodology known as optogenetics was developed, which uses light to control specific cell types of neurons, either to activate or inhibit neuronal firings. The strength of optogenetics in neuroscience is the precise control of neuronal activities in millisecond scale and the ability to dissect the neural circuits and cell types to understand their functions. There have been substantial advancements made in the field of sleep research through the implementation of optogenetics. This review provides a brief introduction on the optogenetics and a consolidated summary of recent findings published in sleep research using optogenetics.
Victor G,Cicirelli 한국노년학연구회 2003 한국 노년학연구 Vol.12 No.-
Based on exchange/equity theory, the study explored the views of older women in assisted living facilities regarding reciprocity of exchange of social support with a close friend. Study participants were 92 chronically ill older women aged 65 to 98. In individual interviews, participants responded to 4 vignettes depicting situations in which there was an imbalance of exchange with a friend. Background characteristics of the participants were also assessed. Qualitative analysis was used to examine responses to the vignette situations. Although most of these older women affirmed reciprocity norms to a degree, findings could be better explained by norms of altruism and of loyalty to friends, despite inequality of exchange associated with infirmities of aging.