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Truong Van Tri,Al-Shakfa Fidaa,Roberge David,Masucci Giuseppina Laura,Tran Thi Phuoc Yen,Dib Rama,Yuh Sung-Joo,Wang Zhi 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.4
Study Design: Retrospective study.Purpose: The purpose of this study was to see how well the Tomita score, revised Tokuhashi score, modified Bauer score, Van der Linden score, classic Skeletal Oncology Research Group (SORG) algorithm, SORG nomogram, and New England Spinal Metastasis Score (NESMS) predicted 3-month, 6-month, and 1-year survival of non-surgical lung cancer spinal metastases.Overview of Literature: There has been no study assessing the performance of prognostic scores for non-surgical lung cancer spinal metastases.Methods: Data analysis was carried out to identify the variables that had a significant impact on survival. For all patients with spinal metastasis from lung cancer who received non-surgical treatment, the Tomita score, revised Tokuhashi score, modified Bauer score, Van der Linden score, classic SORG algorithm, SORG nomogram, and NESMS were calculated. The performance of the scoring systems was assessed by using receiver operating characteristic (ROC) curves at 3 months, 6 months, and 12 months. The predictive accuracy of the scoring systems was quantified using the area under the ROC curve (AUC).Results: A total of 127 patients are included in the present study. The median survival of the population study was 5.3 months (95% confidence interval [CI], 3.7–9.6 months). Low hemoglobin was associated with shorter survival (hazard ratio [HR], 1.49; 95% CI, 1.00–2.23; p =0.049), while targeted therapy after spinal metastasis was associated with longer survival (HR, 0.34; 95% CI, 0.21–0.51; p <0.001). In the multivariate analysis, targeted therapy was independently associated with longer survival (HR, 0.3; 95% CI, 0.17–0.5; p <0.001). The AUC of the time-dependent ROC curves for the above prognostic scores revealed all of them performed poorly (AUC <0.7).Conclusions: The seven scoring systems investigated are ineffective at predicting survival in patients with spinal metastasis from lung cancer who are treated non-surgically.
Hoan Minh Tran,Lan Ngoc Tan Phan,Thang Van Le,Thuy Thuy Truong,Tam Huu Nguyen,Khuong Tung Truong,Le-Thu T. Nguyen,Mai Thanh Phong,Ha Tran Nguyen 한국고분자학회 2019 폴리머 Vol.43 No.4
A novel organic photocatalyst, 4-(10H-phenothiazin-10-yl)-N,N-diphenylaniline (PDPA) has been successfully synthesized from triphenylamine and phenothiazine moiety via Buchwald-Hartwig C-N coupling. The chemical structure of catalyst was characterized via proton nuclear magnetic resonance (1H NMR) and the optical properties were investigated via UV-vis spectroscopy. The PDPA has been applied as an organic photocatalyst for metal free atom transfer radical polymerization (O-ATRP). The well-controlled molecular weights of polymethacrylates have been obtained with high yield of 95% and narrow polydispersity index (Đ).
High-Resolution Simulations for Vietnam - Methodology and Evaluation of Current Climate
Jack Katzfey,Kim Nguyen,John McGregor,Peter Hoffmann,Suppiah Ramasamy,Hiep Van Nguyen,Mai Van Khiem,Thang Van Nguyen,Kien Ba Truong,Thang Van Vu,Hien Thuan Nguyen,Tran Thuc,Doan Ha Phong,Bang Thanh Ng 한국기상학회 2016 Asia-Pacific Journal of Atmospheric Sciences Vol.52 No.2
To assist the government of Vietnam in its efforts to better understand the impacts of climate change and prioritise its adaptation measures, dynamically downscaled climate change projections were produced across Vietnam. Two Regional Climate Models (RCMs) were used: CSIRO’s variable-resolution Conformal-Cubic Atmospheric Model (CCAM) and the limited-area model Regional Climate Model system version 4.2 (RegCM4.2). First, global CCAM simulations were completed using bias- and variance-corrected sea surface temperatures as well as sea ice concentrations from six Coupled Model Intercomparison Project Phase 5 (CMIP5) global climate models. This approach is different from other downscaling approaches as it does not use any atmospheric fields from the GCMs. The global CCAM simulations were then further downscaled to 10 km using CCAM and to 20 km using RegCM4.2. Evaluations of temperature and precipitation for the current climate (1980-2000) were completed using station data as well as various gridded observational datasets. The RCMs were able to reproduce reasonably well most of the important characteristics of observed spatial patterns and annual cycles of temperature. Average and minimum temperatures were well simulated (biases generally less than 1oC), while maximum temperatures had biases of around 1oC. For precipitation, although the RCMs captured the annual cycle, RegCM4.2 was too dry in Oct.-Nov. (−60% bias), while CCAM was too wet in Dec.- Mar. (130% bias). Both models were too dry in summer and too wet in winter (especially in northern Vietnam). The ability of the ensemble simulations to capture current climate increases confidence in the simulations of future climate.
Bioinformatic identification and expression analysis of the chicken B cell lymphoma (BCL) gene
Van Thai Than,Ha Thi Thanh Tran,Duc Viet Ly,Hoang Vu Dang,Minh Nam Nguyen,Anh Duc Truong 한국유전학회 2019 Genes & Genomics Vol.41 No.10
Background B cell lymphoma (BCL) families play an important role in apoptosis as a growth factor, cell death programming, cytokine expression and immune-related genes expression. Objectives In this study, to investigate the roles of BCLs, we performed genome-wide identification, expression and functional analyses of the BCL family in chicken. Methods Chicken BCLs genes were identified and analyzed by using bioinformatics approach. Expression profiles and Hierarchical cluster analysis of the BCLs genes in different chicken tissues were obtained from the genome-wide RNA-seq in the GEO, and Cluster and Java Treeview, respectively. Results A total of 16 BCLs genes were identified from the chicken genome, which could be further classified into five distinct groups in the phylogenetic tree. On the other hand, the interaction among BCLs proteins and between BCLs proteins with NF-κB subunits are limited, indicating that the remaining the functions of BCLs protein could be investigated in chicken. Moreover, KEGG pathway analysis indicated that BCL gene family was involved in regulation of apoptotic and immune response. Finally, BCL gene family was differentially expressed in chicken tissues, pathogen infection and growth stages of early chicken early embryo. Conclusion This study provides significant insights into the potential functions of BCLs in chicken, including the regulation of apoptosis, cell death and expression of immune-related genes.
Experimental study on mechanical behaviors of injection molded PC/PMMA blends
Van Thanh Hoang,Quang Bang Tao,Bich-Tram Truong-Le,Minh Sang Tran,Duc Binh Luu 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.9
Mechanical property is one of the quite important factors of optical articles. Most of pure plastics materials are rarely found to have both high strength and toughness. The paper aims to investigate mechanical properties of polymethyl methacrylate and polycarbonate (PC/PMMA) blends by means of injection molding process and optimization technique. In this study, four factors including composition, packing pressure, melt temperature, and cooling time are taken into account. Experimental results show that the composition is found as the most significant factor for improving the mechanical properties of PC/PMMA blends with confidence level of 95 %. Meanwhile, melt temperature and cooling time are also the most significant parameters for enhancing impact strength with 95 % confidence level. In addition, the mechanical properties of the PC/PMMA plastics composites have been enhanced significantly. Specifically, average tensile yield strength, impact strength, and average elongation are 76.5 MPa, 7429.5 J/m 2 , and 17.5 mm, respectively.
Truong Duong Thuy Thi,Tran Trang Huyen Thi,Nguyen Tam Thanh Thi,Tran Van Hong Thi 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.5
BACKGROUND/OBJECTIVES Although children of ethnic minority groups are experiencing a transition from a predominance of undernutrition to overnutrition, there is little evidence of a dual-malnutrition burden. Therefore, this study examined the double burden of malnutrition among school-aged ethnic minority children living in mountainous areas and its association with their diets. SUBJECTS/METHODS A cross-sectional study was conducted from September 2019 to March 2020 in 3 mountainous areas of Northern Vietnam among 1,556 ethnic minority school-aged children. The prevalence of under-nutrition (stunting and thinness) and over-nutrition (overweight and obesity) were measured using the WHO 2006 child growth standards (height-for-age and BMI-for-age Z-score). Nutritional practices were evaluated by the frequency of food consumption based on a 4-level scale. RESULTS The percentage of children with stunting and thinness were 14.0% and 5.4%, respectively, while the figure for overweight/obesity was 9.4%. The factors positively associated with stunting were living in a family with more than 2 children or being Muong/other ethnicities compared to the Tay ethnicity. Children who consumed fish/shrimps/crabs or milk weekly/daily were less likely to be undernourished compared to those who never consumed these foods. By contrast, children who never consumed foods rich in vitamin A precursors and vitamin A and fruit or consumed daily snacks/junk food were more likely to be overweight/obese. CONCLUSIONS Undernutrition remains a common issue among school-aged children and adolescents of ethnic minority groups, while over-nutrition exists simultaneously. Public health nutrition programs promoting adequate diets and positive lifestyle changes related to nutrition are essential to tackle the double burden of malnutrition among ethnic minority children.