http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Ulrike Braun,Claus G. Bannick 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5
The occurrence of microplastic (MP) in environment is of high public interest. Although in the environmental field already lot of works exist regarding microplastic analysis, the harmonisation is still pending, because of the complexity of environmental matrix and the existing methods. The analysis of bottled water is on the one hand side a relatively simple task (low content of natural, particle matter) and on the other hand side the expected microplastic particles are restricted in general to the packing material. Therefore, the analysis of such food products also regarding the public concern on human health is a first step in the direction of standardisation. In the presentation, we will present the development of a smart filter crucible, which is a sample preparation tool and analysis container in one solution for the determination of MP mass content in bottled beverages, using thermo-analytical detection methods (thermal extraction desorption gas chromatography mass spectroscopy, TED-GC/MS). The present technique of filtration can be applied easily and quickly for beverage samples for MP detection down to particle sizes of 5 μm, allowing a representative result for the samples. Furthermore, we will present the state of harmonisation and standardisation, including national research activities in Germany, as well as the actual progress of European and International Standardisation in ISO and CEN.
Enhanced Smart Tourism and its Role in Reshaping the Tourism Industry
Ulrike Gretzel,Hyunae Lee,Eunji Lee,Namho Chung,Chulmo Koo Smart Tourism Research Center 2023 Journal of smart tourism Vol.3 No.4
This paper explores the concept of enhanced smart tourism as a response to the challenges and opportunities arising in the post-pandemic tourism landscape. The COVID-19 pandemic has not only halted the global tourism industry but also prompted a reevaluation of its sustainability, technological integration, and impact on local communities. The need for a paradigm shift in tourism is emphasized, focusing on digitalization, innovation, and resilience. Enhanced smart tourism is characterized by a shift from traditional practices to innovative governance models, increased emphasis on sustainability, and the integration of technology for better management and visitor experiences. The paper discusses the four pillars of enhanced smart tourism - Technology, Sustainability, Accessibility/Mobility, and Innovation/Creativity, and their expansion in the post-pandemic era. Furthermore, the significant role of data in smart tourism is examined, highlighting the importance of data valuation, management, and ethics. The paper proposes frameworks and methods for data valuation and emphasizes the necessity of a comprehensive approach to data within the smart tourism ecosystem. The conclusion points to the need for further empirical and conceptual research to fully realize the potential of enhanced smart tourism.
Comparison of different methods for the establishment of RNA silencing in plants
Ulrike Manske,Jorg Landsmann,Antje Dietz-Pfeilstetter 한국식물생명공학회 2017 Plant biotechnology reports Vol.11 No.2
RNA interference (RNAi) occurs naturally in plants and is involved in developmental gene regulation as well as in transposon silencing and defence against viruses. RNAi is initiated by small double-stranded RNAs (dsRNAs) of different origins, eventually leading to the silencing of genes with complementary sequences. Besides its use as a basic tool to study gene function, RNAi has widely been exploited for the generation of pathogen resistant crops and for modifying plant metabolism. For the elucidation of gene functions, silencing-inducing dsRNA is often delivered transiently by means of agroinfiltration. This method is independent of plant regeneration and allows rapid testing of multiple silencing constructs. To get more insight into the applicability of transient gene silencing, we compared a variety of different transient and stable approaches to induce silencing of the b-glucuronidase (gus) transgene by the expression of gus hairpin (hpGus) transcripts. While stable expression of the hairpin always resulted in specific gene silencing, transiently expressed hpGus transcripts could only trigger silencing when the hairpin construct was introduced simultaneously with or prior to the target gene.
Marine-Derived Pharmaceuticals - Challenges and Opportunities
( Ulrike Lindequist ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.6
Marine biosphere is the largest one of the earth and harbors an enormous number of different organisms. Living conditions differ fundamentally from those in terrestrial environment. The production of specific secondary metabolites is an important adaption mechanism of marine organisms to survive in the sea. These metabolites possess biological activities which make them interesting as possible drugs for human. The review presents sources, chemistry, production and pharmacology of FDA approved marine derived pharmaceuticals arranged according to their therapeutic indication. Four of the presently seven approved drugs are used for the treatment of cancer. Each another one is applicated for treatment of viral diseases, chronic pain and to lower triglyceride level in blood. Some other products are of interest in diagnostic and as experimental tools. Besides, this article describes challenges in drug development from marine sources, especially the supply problem.
Marine-Derived Pharmaceuticals - Challenges and Opportunities
Lindequist, Ulrike The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.6
Marine biosphere is the largest one of the earth and harbors an enormous number of different organisms. Living conditions differ fundamentally from those in terrestrial environment. The production of specific secondary metabolites is an important adaption mechanism of marine organisms to survive in the sea. These metabolites possess biological activities which make them interesting as possible drugs for human. The review presents sources, chemistry, production and pharmacology of FDA approved marine derived pharmaceuticals arranged according to their therapeutic indication. Four of the presently seven approved drugs are used for the treatment of cancer. Each another one is applicated for treatment of viral diseases, chronic pain and to lower triglyceride level in blood. Some other products are of interest in diagnostic and as experimental tools. Besides, this article describes challenges in drug development from marine sources, especially the supply problem.