백서(白鼠)의 신경병리성(神經病理性) 동통(疼痛)에 대한 후계(後谿),위중(委中) 혈위(穴位) 호침료법(毫鍼療法)과 레이저 침습조사(侵襲照射) 침료법(鍼療法)과의 비교(比較) 연구(硏究)

위통순 ( Tung Sheun Wei ),윤대환 ( Dae Hwan Youn ),윤여충 ( Yeo Chung Youn ),나창수 ( Chang Su Na ) 대한경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.2

Objective: We have studied the effects of acupuncture and low level He-Ne laser therapy(LLLT) at SI3, BL40 on the tibial, sural nerve injury due to sports-damage or traffic accident and L5 spinal nerve ligature model like general herniation of nucleus pulposus(HNP) in a rat of neuropathic pain. Methods: A model of neuropathic pain was made by injuring tibial nerve and sural nerve while common peroneal nerve was maintained. Also, it was made by isolating left 5th lumbar spinal nerve. Three weeks after the neuropathic surgery, acupuncture and LLLT was injected at SI3, BL40 one time a day for one week. LLLT was divided three groups, that is LLLT-1(5mW), LLLT-2(10mW) and LLLT-3(30mW). After that, we examined the withdrawal response of neuropathic rats` legs by Von frey filament and acetone stimulation. And also we examined c-Fos, Nocieptin and KOR-3 in the midbrain central gray of neuropathic rats. Results: As we have observed the effect of mechanical allodynia, LLLT-3 group were diminished on 4 day, 5 day, 6 day and 7 day in the resection model compared with control model, LLLT-1 group were diminished on 5 day, LLLT-2 group were diminished on 3 day and 6 day, LLLT-3 group were diminished on 3 day, 4 day, 5 day, 6 day and 7 day in connected model compared with control group. As we have observed the effect of cold allodynia, LLLT-3 group were diminished on 7 day in the resection model compared with control model, LLLT-1 group were diminished on 6 day, 7 day, LLLT-3 group were diminished on 7 day in connected model compared with control group. As we have observed the effect of activity of c-Fos in the central gray part, LLLT-3 were diminished in resection model compared with control group, LLLT-1 group were diminished in connected model compared with control group. As we have observed the effect of activity of Nociceptin in the central gray part, resection model were not increased compared with control group, LLLT-1 group and LLLT-3 group were increased in connected model compared with control model. As we have observed the effect of activity of KOR-3 in the central gray part, resection model were not increased compared with control group, LLLT-3 group were increased in connected model compared with control model. Conclusions: We have noticed that LLLT-1 and LLLT-3 group have more controllable effect than acupuncture group. This study can be used in clinical therapy for neuropathic pain. But it is not reliability that Nociceptin and KOR-3 have effectively to control pain. Therefore We have to follow up about that.

痿證으로 진단한 하지마비 환자의 치험 1례

위통순(Tung Sheun Wei) 한의병리학회 2006 동의생리병리학회지 Vol.20 No.3

위증(療證)으로 진단한 하지마비 환자의 치험 1례

위통순,Wei, Tung-Sheun 대한동의생리학회 2006 동의생리병리학회지 Vol.20 No.6

Wei symptom(?證) is symptom that reveals muscle relaxation without contraction and muscle relaxation occurs in the lower or upper limb, in severe case, leads to death. This is the clinical report about the Wei symptom(?證)-patient doubt as Transverse Myelitis and Conversion Disorder. The patient was treated by acupuncture, moxibustion, herb medication(十全大補湯), electriccal stimulation theraphy, Bee Venom acupuncture, and had significant improvement in Wei symptom(?證). these results suggest the surface temperature differ remarkably from before being treated. The temperature is measured by using Digital Infrared Thermal Imaging(DITI). The results suggest that oriental medicare is an effective treatment for Wei symptom. We expected that therapeutic value of treatment of both leg Paralysis in the oriental medicine will be higher if more clinical studies and researches are accomplished.

임신 천식 환자 1례에 대한 임상적 고찰

위통순,양승정,Wei, Tung-Sheun,Yang, Seung-Jung 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.1

Purpose: The purpose of this case study is to report the effect of oriental and western medicine combination therapy for the Asthma during the period of pregnancy. Methods: We treated the patient who had the Asthma during the period of pregnancy and visited Dongshin University oriental hospital. The patient in this case was admitted for 9days due to the Asthma on the twenty-third week period of pregnancy. In consideration of pregnancy, this patient was treated with oriental and western medicine combination treatments such as herb medicine, acupuncture, herbal acupuncture therapy, and so forth. Results: There was remarkable improvement in condition of the patient, treated by oriental and western medicine combination therapy. Conclusion: We confirmed that western medicine treatment is effective in curuing with an urgent symptoms, but there is a limit to complete recovery or prevention. On the other hand. it proves that oriental medicine treatment is proficient with continuous treatment effect, but further studies are needed.

단미음료제(單味飮料劑)를 통한 소갈(消渴)의 치료(治療)에 관한 고찰(考察)

박춘하,위통순,김용성,이경환,Park Choon-Ha,Wei Tung-Sheun,Kim Yong-Sung,Lee Kyung-Hwan 대한한의학방제학회 2002 大韓韓醫學方劑學會誌 Vol.10 No.2

In Oriental medicine, So-gal(消渴) is similar to Diabetes Mellitus in the symptoms. In the medical treatment of So-gal(消渴), one kind of herb medicine is recorded in ancent medicine literatures. That herb medicine is a juice of vegetable drunken with herb medicine of So-gal(消渴). Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁), sang-gang-jup(生薑汁) etc. is that. In that juices, Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁) have sweety tastes, and cold nature. So they cure So-gal(消渴) come from dry and hot nature. Sang-gang-jup(生薑汁) is different with others in the taste and nature that sweety and hot taste and hot nature. Sang-gang-jup(生薑汁) cure the sequela of So-gal(消渴) by his hot nature. We think In Diabetes Mellitus, that juice can be used by drink for the treatment of diet because of simility between So-gal(消渴) and DM.

건측(健測) 취혈(取穴) 다종(多種) 침자법(鍼刺法)이 백서(白鼠)의 신경병리성(神經病理性) 동통(疼痛)에 미치는 영향

정정희,조명래,위통순,류충열,Jung, Jung-Hee,Cho, Myung-Rae,Wei, Tung-Sheun,Ryu, Chung-Ryeol 대한침구의학회 2007 대한침구의학회지 Vol.24 No.5

Objectives : To find effects of acupuncture, electro-acupuncture, low level He-Ne laser therapy(LLLT) at $TE_5$, $GB_{41}$ in the neuropathic pain. We made experiment on rats ligated L5 spinal nerve like general herniation of nucleus pulposus(HNP). Methods : A model of neuropathic pain was made by isolating Left 5th lumbar spinal nerve of rats. Three days after the neuropathic surgery, acupuncture and LLLT, electro-acupuncture was injected at $TE_5$, $GB_{41}$ one time a day for a week. Each group was divided two. one is opposite side performed the surgery which is right, another is left side performed the surgery. After that, the author examined the withdrawal response of neuropathic rats' legs by van Frey filament and acetone stimulation. And also the author examined c-Fos, Nociceptin and KOR-3 in the midbrain central gray of neuropathic rats. Results : As we have observed the effect of mechanical allodynia, LT-R group were diminished on 6th day compared with control group, EA-L group, EA-R group and LT-L group were diminished on 7th day compared with control group. As we have observed the effect of cold allodynia, EA-R group were diminished on 6th day, 7th day compared with control group. As we have observed the effect of activity of c-Fos in the central gray part, EA-R group and LT-R group were diminished compared with control group. As we have observed the effect of activity of Nociceptin in the central gray part, EA-R group were a little increased compared with control group but it is not reliability. As we have observed the effect of activity of KOR-3 in the central gray part, EA-R group were significantly increased compared with control group. Conclusions : We have noticed that effect of acupuncture at opposite side of sickness and powerful stimulation could be more effective, because of EA-R group have more controllable effect all test we have done on the other hand EA-L group have only effect on mechanical allodynia. This study can be used in clinical therapy for neuropathic pain. But it is not reliability that Nociceptin have effectively to control pain. Therefore We have to follow up about that.

화담통락탕(化痰通絡湯)이 백서의 뇌혈류변화 및 허혈성 뇌손상에 미치는 영향

박형배,양승정,위통순,박혜선,전상윤,홍석,Park, Hyoung-Bae,Yang, Seung-Jung,Wei, Tung-Sheun,Park, Hye-Sun,Jeon, Sang-Yoon,Hong, Seok 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.1

Objectives & Methods : This present study was performed to investigate the effect of Hwadamtongrak-Tang extract (HTT) on the regulation of cerebral hemodynamics in terms of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP)] in normal and cerebral ischemic rats. Also the effects of HTT on changes in local blood flow, inhibition of LD H activity in neuronal cells, and levels of cytokine production in the serum were determined in the ischemic rat model. The major findings are summarized below. Results : 1. HTT significantly increased rCBF in a dose-dependent manner, but MABP was not changed by HTT treatment. These results suggest that HTT may increase rCBF by dilating cerebral arterial diameter. 2. HTT-induced increase in rCBF was blocked by pretreatment with cyclooxygenase inhibitor indomethacin (IDN, 1 mg/kg, i.p.) and MABP was significantly increased by ID N. 3. Pretreatment of methylene blue $(MTB,\;10\;{\mu}g/kg,\;i.p.)$, an inhibitor of guanylate cyclase, significantly decreased both rCBP and MABP in HTT-treated rats. 4. HTT treatment significantly increased rCBP to a stable level during the period of cerebral reperfusion. 5. HTT significantly inhibited LD H activity in neuronal cells, suggesting a neuroprotection by HTT. 6. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after middle cerebral arterial occlusion in HTT-treated rats. IL-10 levels in the serum were significantly increased by HTT treatment whereas transforming growth factor $(TGF)-{\beta}$ levels were similar between HTT-treated and control groups. 7. Serum interleukin $(IL)-1{\beta}$ and tumor necrosis factor $(TNF)-{\alpha}$ levels were significantly decreased in the femoral artery 1 hr after reperfusion in HTT-treated rats. Serum IL-10 levels were significantly decreased in HTT-treated rats compared with the control group, and no significant changes in $(TGF)-{\beta}$ in the serum were observed by HTT treatment. Conclusions: The present data suggest that HTT may have an anti-ischemic effect via the improvement of cerebral hemodynamics and thus protect the brain from ischemic damage.

테이핑 요법을 병용한 한방치료로 호전된 안면신경마비 환자 치험 12례

이동현(Dong Hyun Lee),나건호(Gun Ho Na),강수우(Sue Yuo Chiang),정정희(Jeong Hui Jeong),위통순(Tung Sheun Wei),윤여충(Yeo Choong Yoon) 한의병리학회 2006 동의생리병리학회지 Vol.20 No.4