두 개의 외연 이야기

Wei-Tien Dylan Tsai(蔡維天),林姃炫(번역자) 중국어문논역학회 2019 中國語文論譯叢刊 Vol.0 No.44

본고는 Dylan Tsai(2015)의 전반부를 번역한 것이다. Tsai의 연구성과는 중국어 기능성분의 지형도를 통해 중국어 문법 구축에 새로운 시야를 제공해준다는 점에서 큰 영향력을 발휘하고 있다. Tsai(2015)에서는 중국어의 기능성분은 경동사구 외연과 좌측 외연이라는 두 특정 영역에 집중되어 있으며, 이는 다시 통사-의미 접합면에서 각각 동반성과인과성에 결부되어 있음을 밝히고 있다. 의문/재귀 부사어, 경동사, 부가논항, 목적어 전치 등 중국어 및 언어 교차적인 다양한 사례들은 내부-외부 이분법의 존재에 강력한 입증자료를 제공해 준다. 이러한 연구결과는 지형학적인 접근법에 기초하여 통사-의미의 사상관계를 폭넓게 이해하는데 크게 기여하고 있다. This paper is a translation of the first half part of Tsai(2015)’s influential work, which provides new insights into the architecture of Chinese grammar, particularly in mapping out the topography of Chinese functional elements. Tsai shows that the distribution of Chinese functional elements is concentrated in two specific areas (i.e., the vP periphery and the left periphery), which in turn are associated with comitativity and causality respectively through the syntax-semantics interface. Both language-internal and cross-linguistic evidence from wh-/reflexive adverbials, light verbs, applicatives, and object fronting lend strong support to the existence of the inner-outer dichotomy. These findings make a great contribution to the full understanding of the nature of syntax-semantics mapping under the cartographic approach.

Change to Ensure Continuity - The Extraordinary Ceremony Dabei Chan : Transformations of Chinese Buddhist Music in England

Tsai,Tsan-Huang 아시아음악학회 2002 Asian Musicology Vol.1 No.-

ACTIVATOR를 이용한 편측성 구치부 반대교합의 치험예

담재화,전윤식 대한치과교정학회 1988 대한치과교정학회지 Vol.18 No.2

The author evaluated the effect of wunderer activator and karwetzky's u-bow activator for correction of anterior and posterior crossbite and mandibular shift to the Rt. or Lt. side. The results were as follows. 1. correction of anterior and posterior corss bite. 2. correction of mandibular shift to the unilateral side. 3. slightly down and backward rotation of mandible was occured.

An Implementation of the Enhanced-CAN BUS Network Connection in CAR Real-Time Embedded Software System

Chun-Shian Tsai,Kun-Shien Tsai,Ming-Tsai Hsu 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

Today’s automobile is featuring a large number of Electronic Control Units (ECUs). This will increase the system complexity, which will consequently increase the difficulties of programming design and safety and the software cost. Therefore, it is important to provide a reliable, real-time, effective and eventually a low-cost software development tool in the automotive industrial market. ERIKA Enterprise provides an open source for multi-processor real-time operating system kernel, implementing a collection of application programming interfaces similar to those of OSEK/VDX standard for automotive embedded controllers. In this paper, we research the automotive software framework for ERIKA Enterprise, and through the conducting of ERIKA software, the real time operating system for OSEK can be ported (embedded) into target ECU hardware in easily. Finally, we propose a demonstrative application for enhanced CAN (ECAN) bus network connection to show how real-time transmission of data frames through ECAN bus network connection is guaranteed by ERIKA Enterprise.

Improvement of ulcerative colitis control by searching and restricting of inflammatory trigger factors in daily clinical practice

Kun-Yu Tsai,Jeng-Fu You,Tzong-Yun Tsai,Yih Jong Chern,Yu-Jen Hsu,Shu-Huan Huang,Wen-Sy Tsai 대한장연구학회 2023 Intestinal Research Vol.21 No.1

Background/Aims: Exacerbating factors of ulcerative colitis (UC) are multiple and complex with individual influence. We aimed to evaluate the efficacy of disease control by searching and restricting inflammation trigger factors of UC relapse individually in daily clinical practice. Methods: Both patients with UC history or new diagnosis were asked to avoid dairy products at first doctor visit. Individual-reported potential trigger factors were restricted when UC flared up (Mayo endoscopy score ≥1) from remission status. The remission rate, duration to remission and medication were analyzed between the groups of factor restriction complete, incomplete and unknown. Results: The total remission rate was 91.7% of 108 patients with complete restriction of dairy product. The duration to remission of UC history group was significantly longer than that of new diagnosis group (88.5 days vs. 43.4 days, P=0.006) in patients with initial endoscopic score 2–3, but no difference in patients with score 1. After first remission, the inflammation trigger factors in 161 relapse episodes of 72 patients were multiple and personal. Milk/dairy products, herb medicine/Chinese tonic food and dietary supplement were the common factors, followed by psychological issues, non-dietary factors (smoking cessation, cosmetic products) and discontinuation of medication by patients themselves. Factor unknown accounted for 14.1% of patients. The benefits of factor complete restriction included shorter duration to remission (P<0.001), less steroid and biological agent use (P=0.022) when compared to incomplete restriction or factor unknown group. Conclusions: Restriction of dairy diet first then searching and restricting trigger factors personally if UC relapse can improve the disease control and downgrade the medication usage of UC patients in daily clinical practice.

Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency

Tsai Yi-Chih,Chen Su-Liang,Peng Shu-Ling,Tsai Ya-Li,Chang Zuong-Ming,Chang Vincent Hung-Shu,Ch’ang Hui-Ju 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

Krüppel-like factor 10 (KLF10) is a tumor suppressor in multiple cancers. In a murine model of spontaneous pancreatic adenocarcinoma (PDAC), additional KLF10 depletion accelerated distant metastasis. However, Klf10 knockout mice, which suffer from metabolic disorders, do not develop malignancy. The mechanisms of KLF10 in PDAC progression deserve further exploration. KLF10-depleted and KLF10-overexpressing PDAC cells were established to measure epithelial-mesenchymal transition (EMT), glycolysis, and migration ability. A murine model was established to evaluate the benefit of genetic or pharmacological manipulation in KLF10-depleted PDAC cells (PDACshKLF10). Correlations of KLF10 deficiency with rapid metastasis, elevated EMT, and glycolysis were demonstrated in resected PDAC tissues, in vitro assays, and murine models. We identified sirtuin 6 (SIRT6) as an essential mediator of KLF10 that modulates EMT and glucose homeostasis. Overexpressing SIRT6 reversed the migratory and glycolytic phenotypes of PDACshKLF10 cells. Linoleic acid, a polyunsaturated essential fatty acid, upregulated SIRT6 and prolonged the survival of mice injected with PDACshKLF10. Modulating HIF1α and NFκB revealed that EMT and glycolysis in PDAC cells were coordinately regulated upstream by KLF10/SIRT6 signaling. Our study demonstrated a novel KLF10/SIRT6 pathway that modulated EMT and glycolysis coordinately via NFκB and HIF1α. Activation of KLF10/SIRT6 signaling ameliorated the distant progression of PDAC. Clinical Trial Registration: ClinicalTrials.gov. identifier: NCT01666184.

Effects of fermented soybean meal with Bacillus velezensis, Lactobacillus spp. or their combination on broiler performance, gut antioxidant activity and microflora

Tsai, C.F.,Lin, L.J.,Wang, C.H.,Tsai, C.S.,Chang, S.C.,Lee, T.T. Asian Australasian Association of Animal Productio 2022 Animal Bioscience Vol.35 No.12

Objective: A series of experiment were conducted to evaluate the effects of replacing a part of soybean meal (SBM) at 6% of broiler diets with fermented soybean meal (FSBM) obtained by single or two-stage fermentation by measuring growth performance, antioxidant activity in the jejunum and distal intestinal microflora. Methods: Soybean meal samples were prepared by single-stage fermentation using Bacillus velezensis (Bv) (FSBM_B), or Lactobacillus spp. (as commercial control) (FSBM_L). Additional SBM sample was prepared by two-stage fermentation using Bv and subsequently using Lactobacillus brevis ATCC 367 (Lb) (FSBM_B+L). Enzyme activity, chemical composition, trichloroethanoic acid-nitrogen solubility index (TCA-NSI) and antioxidant activity were measured. Then, in an in vivo study, 320 Ross308 broilers were divided into four groups with ad libitum supply of feed and water. Four groups were fed either a corn-soybean meal diet (SBM), or one of fermented SBM diets (FSBM_B+L, FSBM_B, and FSBM_L). Growth, serum characteristics, microflora, and the mRNA expression of selected genes were measured. Results: Compared to SBM, FSBM_B+L contained lower galacto-oligosaccharide, allergic protein, and trypsin inhibitor, and higher TCA-NSI by about three times (p<0.05). Reducing power and 1,1-diphenyl-2-picrylhydrazyl free radical scavenging ability correlated positively with the TCA-NSI content in FSBM. Growth performances were not significantly different among four groups. In jejunum of 35-day-old broilers, partial replacement of SBM by FSBM_B+L increased the activity of superoxide dismutase and catalase (CAT), and the FSBM_B group had the highest catalase activity (p<0.05). Partial replacement of SBM by FSBM increased relative mRNA expressions of nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), and peptide transporter 1 (PepT1) (p<0.05); however, FSBM_B+L increased CAT mRNA level to 5 times of the control (p<0.05). Conclusion: Using Bv- and Lb-processed SBM through two-stage fermentation to partially replace 6% of diets will improve the gut's antioxidant activity under commercial breeding in broilers.

Study on a Binder by Using Porcine Blood Plasma Transglutaminase, Thrombin and Fibrinogen

Tsai, Chong-Ming,Tseng, Tsai-Fuh,Yang, Jeng-Huh,Chen, Ming-Tsao Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.1

The purpose of this study was to prepare a binder containing porcine blood transglutaminase (TGase), thrombin and fibrinogen. Extracted TGase, thrombin and fibrinogen were used alone or mixed with different proportions of their volume (v/v/v) by nine combinations as follows were 0.5:1:15, 0.5:1:20, 0.5:1:25, 1:1:15, 1:1:20, 1:1:25, 1.5:1:15, 1.5:1:20 and 1.5:1:25, respectively. Five ml of each combination were mixed with 0.6 ml of 0.25 M calcium chloride before experiment. After storage at 4C for 0, 1, 2, 3, 4 and 5 weeks, enzyme activity, total plate count, pH value, and SDS-PAGE of TGase, thrombin and fibrinogen were tested and pH value, clotting time and gel strength of the nine combination binders were determined. The results showed that total plate count of thrombin and pH value of TGase were significantly higher (p<0.05) than in other treatments. SDS-PAGE results showed that purified TGase, thrombin and fibrinogen from porcine blood plasma compared with commercial products (Sigma) had the same band patterns and nine different combination binders had no significant effect. Enzymatic activity of TGase and thrombin decreased as storage time increased. Total plate count of TGase, thrombin and fibrinogen and clotting time of the binder increased as storage time increased. The higher amount of fibrinogen in combinations, the stronger the gel strength.

Porcine Blood Plasma Transgluataminase Combined with Thrombin and Fibrinogen as a Binder in Restructured Meat

Tseng, Tsai-Fuh,Tsai, Chong-Ming,Yang, Jeng-Huh,Chen, Ming-Tsao Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.7

The purpose of this study was to use pig blood plasma transglutaminase (TGase) combined with thrombin and fibrinogen as a binder, which was applied to restructured meat, and to investigate its effect on the restructured meat quality. Pig meat was obtained 10 h post mortem from a traditional market was ground using a 10 mm aperture plate. A binder admixture was added (TGase:thrombin:fibrinogen mixed as 0.5:1:20 (v/v/v) to which was added 12% of its volume of 0.25 M calcium chloride) at 0, 5, 10, 15 and 20% of meat weight. Measurements included cooking loss, shrinkage rate, shear value, total plate count, pH value, TBA value, color difference, tension strength and sensory evaluation. The results showed that ground meat containing 20% w/w of binder admixture had higher cooking loss, shrinkage rate and shear value (p<0.05). Addition of different percentages of binder admixture did not affect total plate count, pH value, TBA value, and sensory evaluation of restructured meat (p>0.05). Tension strength was increased with increased level of binder admixture. Addition up to 15% binder admixture to restructured meat showed better scores of sensory texture, flavor and total acceptability (p<0.05).

Cerebral Microbleeds in Autosomal Dominant Polycystic Kidney Disease

Li-Kai Tsai,Pei-Lung Chen,Hsin-Hsi Tsai,Ya-Fang Chen,Ping-Chun Wu,Jiann-Shing Jeng,Jenq-Wen Huang,Tzong-Shinn Chu,Juliana Tze-Wah Kao 대한뇌졸중학회 2020 Journal of stroke Vol.22 No.1

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