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Purpose We aimed to evaluate health-related quality of life (HRQOL) at 1-year post-diagnosis in breast cancer (BC) patients and its association with overall survival using data from the National Cancer Center Hospital. Materials and Methods Data of a BC cohort were first obtained between 2004 and 2006 and followed up. HRQOL was assessed using EORTC QLQ-C30 and BC specific module QLQ-BR23 few days after diagnosis and 1 year after that. We examined and compared the difference in the two HRQOL scores measured for each patient by the patient’s current survival status. The Cox proportional hazards model was fitted to evaluate the impact of HRQOL on survival, with adjustment for baseline HRQOL and other factors. Results Of 299 enrolled patients, 206 responded at 1-year post-diagnosis (80.6%) and were followed up for 11.6 years on average. At 1-year post-diagnosis, survivors had better HRQOL scores than those who died, although their health status was similar at baseline. Survivors reported significant increase 1 year after diagnosis in global health status and emotional scales. Between the groups, functional scales such as physical, role, and emotional were significantly different. Functional scales, including physical (adjusted hazard ratio [aHR], 0.70), role (aHR, 0.68), emotional (aHR, 0.72), and symptom scales, including fatigue (aHR, 1.34), dyspnea (aHR, 1.29), appetite loss (aHR, 1.24) were significantly associated with overall survival. Patients who were less worried about future health had favorable survival (aHR, 0.83). Conclusion Besides treatment-related symptoms, non-medical aspects at 1-year post-diagnosis, including functional well-being and future perspective, are predictive of long-term survival. Intervention to enhance physical, role, and emotional support for women soon after their BC diagnosis might help to improve disease survival outcomes afterwards.
Based on the research of Article 110 of the Constitution Vietnam in 2013, Article 2 of the Law on Local Government Organization in 2015 and the draft Law on special administrative - economic Unit, the article analyzes the constitutional and the regulations of the Draft law on special administrative - economic unit. From there, make recommendations on the interpretation of the Constitution, on the structure of the law as well as on the location and name of the special administrative - economic unit in Vietnam in the future.
Tran, Phuong Thao,Ngo, Thi Quynh-Mai,Lee, Suhyun,Kim, Okwha,Tran, Huynh Nguyen Khanh,Hwangbo, Cheol,Min, Byung Sun,Lee, Jeong-Hyung ELSEVIER SCIENCE B.V.; AMSTERDAM 2019 JOURNAL OF FUNCTIONAL FOODS Vol.60 No.-
<P><B>Abstract</B></P> <P> <I>Cleistocalyx operculatus</I> flower buds are used as a main ingredient in various beverages and herbal tea in tropical areas. The present study was conducted to investigate anti-osteoclastogenic effects of ethanol extract of <I>C. operculatus</I> flower buds (ECB) and to identify anti-osteoclastogenic compounds in these buds. ECB significantly inhibited RANKL-induced osteoclast differentiation and decreased RANKL-induced the activation of NFATc1. We isolated nineteen compounds from <I>C. operculatus</I> flower buds and found that eight compounds, including maslinic acid (<B>6</B>) and its two coumaroyl analogs (<B>7</B> and <B>8</B>), significantly inhibited RANKL-induced osteoclast formation. Among these, 3-O-<I>trans</I>-<I>p</I>-coumaroyl maslinic acid (<B>8</B>) showed the most potent inhibitory effect on RANKL-induced osteoclastogenesis via impairment of c-Fos and NF-κB activation, and subsequently, NFATc1 activation. These results suggested that identification of the anti-osteoclastogenic compounds from <I>C. operculatus</I> flower buds may extend our understanding of molecular mechanisms underlying biological activities of <I>C. operculatus</I> flower buds for osteoclast-related diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The anti-osteoclastogenic effect of <I>Cleistocalyx operculatus</I> is demonstrated. </LI> <LI> Ethanol extract of <I>C. operculatus</I> flower buds (ECB) inhibits RANKL-induced osteoclastogenesis. </LI> <LI> Eight compounds are identified as anti-osteoclastogenic compounds from ECB. </LI> <LI> Maslinic acid and its two coumaroyl analogs inhibit RANKL-induced NFATc1 activation. </LI> <LI> The mechanism explains the anti-osteoclastogenic effect of C. operculatus flower buds. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Purpose : Foreign direct investment is one of the important economic characteristics in the modern globalized world. The flow of investments into developing economies is increasingly accounting for a large share of global FDI. The purpose of the study is to find out the factors that influence the attraction of foreign investment into developing countries. Research design, data, methodology : The study collected data from 33 countries in Asia, Africa, Latin, Central America, and Caribbean between 1980 and 2019. By using the Eviews, stationary test, fixed effects and random effects test to find variables that have a significant impact on the development of developing countries as well as each region of Asia, Africa, Central South America. Results : The results show that since 1980, financial development, market size, price stability, trade openness, infrastructure capacity and labor force have had a significant impact on FDI inflows to developing countries. However, when separating with Asia, Africa, the Americas, Central America and the Caribbean, different factors determine the FDI inflows of each region. For Asia market size and trade openness are influential factors that have a positive impact on attracting foreign capital inflows. The larger the trade openness, the more FDI inflows are attracted. Similarly, a larger market, encouraging efficient investment, has been particularly attractive to FDI investors in recent decades. For Africa, the level of financial development, market size, trade openness, infrastructure and labor source are the factors that influence the attraction of FDI inflows. While for Central South America, the level of financial development is the most significant variable affecting FDI attraction, followed by market size, labor source and trade openness are positive factors that have a significant impact on FDI inflows. Conclusions : Therefore, In order to promote FDI inflow, the level of financial development, market size, openness of trade, infrastructure construction and workers' resources should be established. And as the analysis shows, different FDI determinants in Asia, Africa, and Latin America are different, so policy planning and enforcement for each region are needed. 지난 10년 동안 세계화가 빠르게 진행됨에 따라 FDI는 선진국에서 신흥국으로, 특히 개발도상국에서 가장 두드러진 특징으로 나타났다. 특히 아시아, 아프리카 및 중남미 국가들은 FDI의주요 대상국으로 부상하였다. 이에 본 논문에서는 1980년대부터 2019년까지 개발도상국의 패널데이터를 이용하여 개도국의 FDI 유입 결정요인이 무엇인지 분석하였다. 분석대상은 개발도상국 33개국 아시아, 아프리카 및 중남미 3개 그룹으로 구분하여, 그룹별 국가에 영향을 주는 FDI결정요인이 무엇인지? FDI에 영향을 주는 종속변수와 금융발전, 시장규모, 거시경제, 인프라시설, 무역개방성, 노동자원 6가지 독립변수로 하여 패널 데이터 분석을 실시하였다. 분석결과 금융발전 수준, 시장 규모, 물가 수준 , 인프라 시설, 무역 개방성, 노동자원이 개발도상국FDI 유입에 긍정적 요인으로 나타났으며, 아시아, 아프리카, 중남미 각 지역에 대한 분석결과를 비교해보면 아시아의 경우 FDI 유입을 촉진하기 위해 시장 규모와 무역 개방성이 FDI 유입요인으로 나타났다, 또한 아프리카의 경우는 인프라와 금융 개발, 중남미 지역의 경우 금융발전 수준, 시장 규모, 노동자원 및 무역 개방성이 각각 FDI에 영향을 준 것으로 분석되었다.
Purpose: This study aimed to investigate inequalities in colorectal cancer (CRC) screening rates in Korea and trends therein usingthe slope index of inequality (SII) and relative index of inequality (RII) across income and education groups. Materials and Methods: Data from the Korean National Cancer Screening Survey, an annually conducted, nationwide cross-sectionalsurvey, were utilized. A total of 17174 men and women aged 50 to 74 years were included for analysis. Prior experience withCRC screening was defined as having either a fecal occult blood test within the past year or a lifetime colonoscopy. CRC screeningrates and annual percentage changes (APCs) were evaluated. Then, SII and RII were calculated to assess inequality in CRCscreening for each survey year. Results: CRC screening rates increased from 23.4% in 2005 to 50.9% in 2015 (APC, 7.8%; 95% CI, 6.0 to 9.6). Upward trends in CRCscreening rates were observed for all age, education, and household income groups. Education inequalities were noted in 2009,2014, and overall pooled estimates in both indices. Income inequalities were inconsistent among survey years, and overall estimatesdid not reach statistical significance. Conclusion: Education inequalities in CRC screening among men and women aged 50 to 74 years were observed in Korea. Noapparent pattern, however, was found for income inequalities. Further studies are needed to thoroughly outline socio-economicinequalities in CRC screening.
전 세계에서 베트남은 기후 변화에 가장 큰 영향을 받는 국가 중 하나이다. 현재 베트남의 기후 변화에 대 한 대응 활동은 텔레비전, 신문, 라디오, 인터넷 등과 같은 미디어에 의존하고 있다. Facebook은 베트남 사 람들이 가장 많이 사용는 소셜 네트워크이다 (베트남 의 페이스북 이용자는 5800만명으로 세계 7위). 그러 나 상대적으로 그것을 기후변화 대응에 이용하고자 하 는 관심은 적은편이다. 이 논문에서는 Facebook의 Audience Insight Tool(AIT)과 온라인 사회학 조사 방법 을 활용하여 Facebook을 통한 기후 변화 대응 활동의 현재 상태 및 효율성을 평가했다. 베트남 Facebook의 기후 변화 대응 팬 페이지의 수는 15개 정도이며, 그중 가장 인기 있는 곳의 팔로워 수가 94,721명에 이른다. 이 연구에서는 베트남에서 가장 방문자가 많은 기후 변화 대응 팬 페이지 2곳을 조사하고 평가 한 결과, Facebook을 통한 기후 변화 대응은 예상 한 것만큼 큰 효과가 없었다. 또한 온라인 설문 조사를 통해 이러한 문제의 원인을 파악해 보고자 하였다. 이 결과는 앞으 로 기후 변화 대응을 할 때 Facebook과 같은 소셜 네트 워크의 강점을 부각시키면서 해결책을 찾고자 하는 기 관들에게 과학적인 밑거름이 될 것이다. Vietnam is one of the countries most affected by climate change. Therefore, communication activities on climate change in Vietnam are focused with various media such as television, newspapers, radio, internet etc. In particular, Facebook social network is a potential media but less interested and developed. In this topic, Audience Insight tool of the Facebook social network and the online sociological survey method were conducted to assess the current status and effectiveness of climate change communication activities via Facebook in Vietnam today. Vietnam ranks seventh in the world with 58 million users. However, the number of climate change communication fanpages has only about 15 fanpages with the largest number of followings is 94,721 persons. Among of the 10 most contented Facebook users in Vietnam today, there is no fanpage related to climate change. The results of research and evaluation two fanpages of climate change communication that are the most and most frequent followers in Vietnam showed that climate change communication via Facebook in Vietnam is not as effective as expected. At the same time, online survey results also pointed out the causes of the above problems. This is the scientific basis for management agencies to find the solutions to promote the strength of Facebook social network in climate change communication in the future.
Reforestation is a primary factor in protecting upland forests providing economic sustenance for livelihood and keeping watersheds intact. In this study, we evaluated the importance of several direct and indirect drivers that can influence people’s decision for reforestation. Acquiring data from Cao Phong district of Vietnam, we utilized Bayesian Network (BN) to analyze how household characteristics, socio-economic status, biophysical environment, institutional support, and farm characteristics influenced reforestation decisions of local people. BN allowed us to identify 1) the main drivers that affect landholders ‘planted forest area, 2) how the key drivers affect among themselves, and 3) what causes constraints in tree planting. We surveyed 100 households for potential drivers, identified significant drivers by using bivariate analysis and stepwise linear regression, and created a BN to predict scenarios with different household’s perception regarding the planted forest area. The results revealed five direct drivers (attitude of household to tree planting, sources of investment capital for planting practice, land area, distance from household to market, experience of participating in forestry program) and seven indirect drivers (information about forestry program, incentives supported for tree planters, land tenure, accessibility to plantation forest, rotation length of planting trees, forest area, household income) that significantly influenced farmers’ reforestation decisions. Constraints in planting trees were due to the difficulties in protecting property from mortality and unreliable profit. Our results can assist design efficient forestry programs in Vietnam and in other comparable areas.
In the training for Vietnamese Bachelor of school (for an audience of foreign students), Vietnamese Literature is one of the compulsory subjects. This is a good subject but it is difficult for foreign students, due to limited language skills. So, how do foreign students get excited to learn Vietnamese Literature and clearly understand literary works of Vietnam? This article raises some experience in the application of the group discussion method based on hierarchical theory of Benjamin Bloom's thinking when we teach Vietnamese Literature for foreign students, particularly students formal system studying at the Faculty of Vietnamese Studies, University of Social Sciences and Humanities - Vietnam National University Ho Chi Minh City. This method helps teachers to maximize the motto “learner-centered”, and also helps students to use effectively P.O.W.E.R. Studying methods (by Professor of Psychology Robert S. Feldman, University of Massachusetts initiated), in order to promote active, positive and creative learning.
Hien nay, Khoa hoc Xa hoi va Nhan van (KHXH&NV) da tro thanh linh vuc nghien cuu mang tinh toan cau. O Viet Nam, nhu cau phat trien khoa hoc ky thuat de dua dat nuoc phat trien, hoi nhap da tro thanh nhu cau buc thiet. Vi vay, trong mot thoi gian dai, cac moi quan tam cua xa hoi hau nhu deu huong ve cac nganh Khoa hoc Tu nhien, va nganh KHXH & NV chua duoc chu trong va dau tu dung muc. Dieu nay da dan den mot thuc trang dang lo ngai la nghien cuu KHXH & NV Viet Nam co su “tut hau” so voi the gioi. Ty le cac bai bao KHXH & NV xuat hien rat “khiem ton” tren cac tap chi quoc te. Qua tim hieu thuc trang nghien cuu KHXH & NV o Viet Nam va tinh hinh nghien cuu KHXH & NV the gioi, bai viet de xuat mot so giai phap nham thuc day nghien cuu KHXH & NV de nganh KHXH & NV Viet Nam phat trien vung manh, huong den hoi nhap va toan cau hoa. Cac giai phap tap trung vao cac van de: Xay dung nguon nhan luc chien luoc, Quy hoach de tai va dinh huong nghien cuu, Day manh hop tac nghien cuu quoc te, Phat trien quy dau tu nghien cuu va thay doi hinh thuc tai tro, danh gia ket qua nghien cuu. Currently, the Social Sciences and Humanities (SSH) has become the field of global research. In Vietnam, the demand for the development of science and technology to national development and integration has become a pressing demand. Therefore, for a long time, almost all the concerns of the society towards the Science and Technology, meanwhile, sector of SSH were not paid due attention and proper investment. This problem has led to a worrying situation that is the Vietnamese Social sciences and Humanities are “lagging behind” in comparison with the countries in the world. The share of SSH articles published is very limited in international journals. Through understanding the reality of SSH research in Vietnam and the situation of SSH research in the world, the article suggested some solutions to in order to promote social sciences and Humanities research, to the SSH in Vietnam to strong development, towards integration and globalization. The solutions focus on the following issues: Building a Strategic Human Resources, Research Orientation and Planning, Promoting International research cooperation, Developing investment funds for research and Changing the form of grants, evaluate of research results.