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RISS 인기검색어
- 검색키워드
- 저자 : Tonatiuh (검색결과 3 건)
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Food Hypersensitivity in Mexican Adults at 18 to 50 Years of Age: A Questionnaire Survey
Martín Bedolla-Barajas,Tonatiuh Ramses Bedolla-Pulido,Alan Salvador Camacho-Peña,Estefanía González-García,Jaime Morales-Romero 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.6
Purpose: There is limited epidemiological evidence of food hypersensitivity (FH) in the adult population. We aimed to determine the prevalence of FH in Mexican adults, their clinical features and to establish common food involved in its appearance. Methods: We designed a cross-sectional study using a fixed quota sampling; 1,126 subjects answered a structured survey to gather information related to FH. Results: The prevalence of FH in adults was 16.7% (95% CI, 14.5% to 18.8%), without statistical significant differences related to gender (women, 17.5% and men, 15.9%) or residential location. The most common clinical manifestations in adults with FH were oral allergy syndrome (70 of 1,126) and urticaria (55 of 1,126). According to category, fruits and vegetables were the most frequent foods to trigger FH (6.12%) and were individually related to shrimp (4.0%), and cow milk (1.5%). Adults under age 25 had a higher frequency of FH (OR, 1.39; 95% CI, 1.01 to 1.91, P <0.001). Personal history of any atopic disease was significantly associated with FH (P <0.0001). Conclusions: The prevalence of FH is relatively high in Mexican adults, and FH is significantly associated with atopic diseases.
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Dietary Biotin Supplementation Impairs Testis Morphology and Sperm Quality
Karina Pasten-Hidalgo,Leticia Riveron-Negrete,Gloria Sicilia-Argumedo,Gustavo Canul-Medina,Tonatiuh Salazar-Anzures,Miguel Tapia-Rodrıguez,Enrique O. Hernandez-Gonzalez,Ana Lilia Roa-Espitia,Carlos Ce 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.5
Supplements containing pharmacological concentrations of biotin are commercially available over the counter. Classical toxicity studies have considered biotin administration as harmless; however, recent investigations have shown that biotin supplementation modifies tissue morphology without changes in toxicity markers, raising concerns about the consequences of morphological changes on tissues' functions and the safety of pharmacological concentrations of the vitamin. Testes are very sensitive to toxicants, and testicular histology is a reliable method to study its function. In this work, we investigated the effects of dietary biotin supplementation on testis morphology and spermatogenesis function using an experimental model, in which we have not observed unfavorable effects on other tissue functions or toxicity markers. Male BALB/cAnNHsd mice were fed a control or a biotin-supplemented diet (1.76 or 97.7 mg biotin/kg diet) for 8 weeks. Compared to the control group, the biotin-supplemented mice presented remarkable testis morphology changes, including increased spermatogonia layers; the cellular mechanism involved is related to increased proliferation. Sperm count and serum testosterone levels were not affected, but spermatozoa motility and morphology were significantly impaired in the biotin-supplemented mice. These results caution against the use of supplements with high concentrations of biotin and indicate that biotin's pharmacological effects on morphology need to be considered in toxicological studies.
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The Output Regulation Problem for Unmodeled Reference/Disturbance Signals Using High-gain Observers
Jesús Alberto Meda-Campaña,Ricardo Ismael Ancona-Bravo,Jonathan Omega Escobedo-Alva,Tonatiuh Hernández-Cortés,Ricardo Tapia-Herrera 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.4
Based on the regulation theory and high-gain observers, in this paper, a controller for tracking and/or rejecting unmodeled but measurable signals is designed. Considering that the measurable reference/disturbance signals are bounded and smooth, it is proven that the missing dynamical models for such signals can be estimated by high-gain observers of dimensions equal to or greater than one. Then, the corresponding high-gain observers are embedded into an auxiliary system, known as the exosystem, allowing in this way, that the regulation theory can be applied and the new equations to be solved are also given. Because the exosystem is directly constructed from the high-gain observers, the proposed controller is robust in the sense that it is capable of tracking/rejecting any bounded and smooth signal as long as the estimations of the high-gain observers are sufficiently accurate. The existence conditions for such a controller are given, and numerical experiments are used to illustrate the efficacy of the proposed approach.
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