정신분열병 환자의 말초 임파구에서 D5도파민 수용체 mRNA의 변화

김형섭,곽용태 용인정신의학연구소 1998 용인정신의학보 Vol.5 No.2

전자토모그래피의 정량적 분석에서 대물렌즈 조리개의 영향

김진규,이상희,권희석,정종만,정원구,이수정,주형태,김윤중 韓國電子顯微鏡學會 2008 Applied microscopy Vol.38 No.4

Electron tomography의 정량적 분석을 위해서 대물렌즈 조리개가 투과빔의 강도에 미치는 영향을 평가하였다. Electron tomography에 도입되는 Beer’s law의 올바른 적용을 위해서는 투과빔은 시료의 기울기에 따른 mass thickness의 변화에 의한 효과만을 반영해야 한다. 그러므로 빔 경로상의 대물렌즈 조리개, 홀더 등에 의한 다른 효과는 제거되어야 한다. 본 연구에서는 대물렌즈 조리개의 cut-off 효과를 120 kV TEM과 Quantifoil holey 카본 시료를 이용하여 상세히 평가하였다. 대물렌즈 조리개를 사용하지 않은 경우와 비교할 때, 30 μm 크기의 대물렌즈 조리개를 통과한 투과전자빔의 강도는 약 16.7%의 감소가 일어난다. 또한 55˚이상의 고경사각 기울기에서는 대물렌즈 조리개의 cut-off 효과에 의해 14.2%의 강도 감소가 추가적으로 발생함을 알 수 있었다. Electron tomography에서 정량적 분석을 위해서는 이러한 대물렌즈 조리개의 영향을 고려해야만 한다. 또한 Beer’s law의 올바른 적용을 위해서는 일련의 기울기에 따른 2차원적 영상은 가능하면 대물렌즈 조리개를 사용하지 않은 상태에서 획득하는 것이 바람직하다. We have evaluated the effects of experimental factors on transmitted electron beam intensities for quantitative analysis in electron tomography. For the correct application of Beer’s law in electron tomography, the transmitted beam intensity should reflect the net effect of mass properties on beam path. So, the any other effects of the objective aperture and the specimen holder on beam path should be removed. The cut-off effects of objective aperture were examined using Quantifoil holey carbon film and a transmission electron microscope operated at 120 kV. The transmitted beam intensities with 30 μm objective aperture dropped about 16.7% compared to electron beam intensities without the objective aperture. Also, the additional losses of about 14.2% at high tilt angles were occurred by cut-off effects of the objective apertures. For the precise quantitative analysis in electron tomography, the effect of the objective aperture on transmitted electron beam intensities should be considered. It is desirable that 2-D tilt series images are obtained without the objective aperture for correct application of Bee’s law.

연 폭로가 남성호르몬에 미치는 영향

김형수,장성훈,이원진,최재욱,박종태,백남원,김록호 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.1

목 적 : 본 연구는 직업성 연 폭로근로자에서 연폭로가 남성 생식기계 독성중 성호르몬에 미치는 영향과 그 정도를 평가하고자 시도되었다.방 법 1998년 하반기에 실시한 일반, 특수건강진단자중 경기도 지역 직업성 연 폭로 근로자 33명과 과거 직업력에서 연 폭로가 없었던 사무직 근로자 33명을 연구대상으로 선정하였다. 연의 생물학적지표로는 혈색소, ZPP, 혈중 연, 및 요중 연을 이용하였으며, 성호르몬으로는 LH, FSH, testos-terone, SHBG 및 FTI를 이용하였다. 연 폭로 지표와 성호르몬과의 상관관계를 조사하였다. 결 과 : 연의 생물학적 지표중 혈색소는 폭로군에서 대조군보다 유의하게 낮았으며, ZPP, 혈중 연및 요중 연등은 폭로군에서 대조군보다 유의하게 높았다. 성호르몬에서 FSH, testosterone, SHBG및 FTI는 모두 폭로군에서 대조군보다 낮았으나 통계적 유의성은 없었다. 폭로군의 성호르몬중에서 연령은 FSH 및 FTI, ZPP는 FSH, 혈중 연은testosterone과 유의한 상관관계가 있었다. 대조군에서 연령은 FSH, testosterone, SHBG 및 FTI와 흡연량은 FSH와 유의한 상관관계가 있었다. 연령군별 폭로군과 대조군의 성호르몬 비교에서 30-39세군의 FTI에서 폭로군이 대조군보다 유의하게 낮았으며 그 밖의 호르몬에서는 모두 유의한 차이가 없었다. 결 론 : 연 폭로군의 FSH, Testosterone, SHBG 및 FTI가 대조군에 비교하여 낮았으나 통계적 유의성은 없었다. 그러나 폭로군에서 연의 생물학적 지표와 일부 성호르몬간에 유의한 상관관계를보였으며 이는 본 연구 대상 근로자의 연 폭로 수준이 일부 성호르몬에 영향이 있음을 보여주는 것으로 판단된다. 향후 이에 대한 지속적인 연구가 진행되어 야 할 것이다. Objectives : This study was performed to evaluate the relationship between biological markers of lead exposure and level of sex. hormones in men occupationally exposed to lead. Methods : In this study, 33 male workers who employed at smelting and battery factories were compared with 33 male workers who were not exposed to lead. As biological markers of lead exposure, hemoglobin, ZPP, blood lead and urine lead were measured. As sex hormones, FSH, LH, testosterone, SHBG and FTI were determined. Results : Hemoglobin level was significantly lower in exposed than in nonexposed group. Level of ZPP, blood lead, and urine lead were significantly higher in exposed than in nonexposed group. There was a trend that level of FSH, testosterone, SHBG, and FTI was lower in exposed than in nonexposed group respectively, but there were no statistical significance. In exposed group, FSH level was correlated with age, ZPP, and blood lead; testosterone level was correlated with hemoglobin, blood lead, urine lead, and SHBG ; and FTI level was correlated with age. Conclusions : Level of some sex hormones were lower in exposed than in nonexposed group but there were no statistical significance between the exposed and the nonexposed group. But level of sex hormones were correlated with several biological markers of lead in exposed group. It suggests that occupational lead exposure might affect sex hormones.

生物學的 改良劑를 利用한 슬럿지의 脫水

김형석,신남철,이태호,박승조 동아대학교 환경문제연구소 1991 硏究報告 Vol.14 No.2

To conditioning sludge to occure in the course of food processing industry, after culturing Rhoodotorula glutinis, dosing a certain amount of culture solution into the sludge and measured the variation of total suspended solids and then, in the aerobic and anaerobic conditions after manage sludge, examining the result of measured specific resitance, the coefficient of cmopressibility to know the dewateability. Arrangements of this result are as follows : 1) As the result of total suspended solids concentration by change of aeration time and the amount of Rhodotorula glutinis dose, optimal dose was Rhodotorula glutinis 10㎖ by 20㎖ sludge. The very suitable aeration time was 4-5days. 2) After dosing biological conditioner(Rhodotorula glutinis) 60㎖ by 11 sludge in aerobic condition, aeration for five days. The results of specific resistance, the coefficient of compressibility were 22.71×10^(5)m/㎏ 1.6, respectively. 3) In the cases of using Rhodotoruls glutinis for biological conditioner, using polymer for chemical conditioner. This results are as follows : Biological conditioner ; the moisture content of sludge cake 77.7% Chemical conditioner ; the moisture content of sludge cake 70.3% But, I author propose that biological conditioner is more useful than chemicals in the total operating and maintenance cost.

외상성 손상과 관련된 상악 측절치 치근형성의 부분 또는 완전정지에 관한 증례보고

김도형,서태휴,이상호 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

Partial or complete arrest of root formation is a rare complication caused by different factors that affects the permanent tooth during root development. The possible factors affecting this complication have been reported in dentin dysplasia, trauma, transmission of the periapical infection of the primary teeth to permanent tooth germ, radiation therapy, and congenital renal disease. One of these factors, traumatic injury to the primary dentition may cause a deflection or displacement of the permanent tooth bud. And the effects of trauma to Hertwig's epithelial root sheath which is essential to root development are the result of the transmission of the traumatic force through the surrounding bone or through the primary tooth. And it can cause critical damage to the normal root development. These tow cases show 2 children who complained of delayed eruption of permanent incisors, who have had a traumatic history during primary dentition. After clincial examination, because they have no more evidence of root formation of maxially lateral incisors. We extracted the permanent maxially lateral incisors which show partial or complete arrest of root formation. We concluded as follows; 1. These two cases show that one is a complete arrest of root formation when injured at 3 years old, the other is a partial arrest of root formation when injured at 5 years old. So, it is considered that direction and magnitude of traumatic forces and injured stage of permanent tooth bud will affect the root development. 2. It was noticed that there was an arrest or loss of Hertwig's epithelial root sheath in the histologic section of the extracted maxially lat. incisors. 3. After continuous observation, if there is a sign of partial or complete arrest of the root formation, impaction, or delay of the eruption of surrounding teeth after the normal root formation stage, extraction is indicated, and it is considered that orthodontic or prosthodontic treatment is needed.

초고주파 소자 해석을 위한 벡터유한요소법에 관한 연구

김영태,김형석 순천향대학교 부설 산업기술연구소 2001 순천향 산업기술연구소논문집 Vol.7 No.1

In this paper, the vector finite elements are abopted to calculate eigenvalues of RF and microwave components. Simulation results show that spurious solutions are completely avoided because of the divergence free nature of the vector elements. This paper seeks to extend these low-order elements to higher orders to improve the accuracy of numerical solutions. Investigation of numerical results for a rectangular waveguide was provided. A vector finite element program was implemented to allow propagation constants and electric field distributions to be directly computed in the rectangular and circular waveguides which are partially filled with the dielectric.

PGA에 의한 교량의 손상도 곡선

김종인,이수철,김태형 대구대학교 산업기술연구소 2003 産業技術硏究 Vol.15 No.1

In performing a risk analysis of structure for earthquake, it is imperative to identify the vulnerability of structures associated with various stages of damage. And the earthquake resisting capability is needed for structures like bridge. So the damage analysis of bridges with or without isolator for earthquake effects is necessary. In this paper, the method for construction of fragility curve is presented. In doing that. general purpose structural analysis program and generally used probability density function are used. The results of structural analysis are represented by Bernoulli distribution which says damage or no damage. By the use of Maximum Likelihood Method. two parameters of lognormal distribution -median and standard deviation - are found. With them, the fragility curves are constructed. In this paper, the fragility curves of bridge are constructed with respect to PGA(Peak Ground Acceleration). The results of this study are as follows: (1) As the result according to research, we got the Fragility Curve to have median and standard deviation as 0.242 0.262 respectively. (2) For PGA, the fragility curve is distributed on relatively wide range of PGA. So it can be a good measure for evaluation of damage effect with respect to PGA.

사질토지반의 테이퍼-펄스말뚝 적용에 관한 실험적 연구

김종인,신영기,김태형,오재학 대구대학교 산업기술연구소 2009 産業技術硏究 Vol.20 No.1

In this paper, a typical drilled shaft to cylindrical and step-tapered pile, pulse pile are produced by the experiment and then captured the ground, forming Jumunjin standard sand model tests loading at sat joy bearing capacity analysis, tapered plus pulse pile was suggestions. Soft ground and the ground around the sandy soil casting of pile to skin friction research tapered pile adjusting the angle and shape for a wide range of variation of pulse pile further study is underway, and the most graft-type model is not presented. Therefore, in this study, the test bearing capacity of existing drilled shaft current analysis by the comparative analysis, as well as skin friction through mutual tapered plus pulse pile bering capacity and allow the unit to analyze and compare the suggestions model would be effective.

PGA에 대한 면진받침의 손상도 해석 연구

김종인,김종윤,김태형 대구대학교 산업기술연구소 2009 産業技術硏究 Vol.20 No.1

Nowadays, The number of occurrence of earthquakes has increased and accordingly the damage caused by earthquake has also increased around the world. Because it is difficult for earthquakes to be predicted in advance and earthquakes often occur concurrently, the needs for the study on the effects of earthquake was increased. Probability theory accumulated during a long time enables engineers to deal with uncertainties of structure quantitatively and to judge stability of structure reasonably. Existing method calculates uncertainties by applying safety factors but the method cannot consider the safety of structures quantitatively. When various stages of structural damage are considered, if the number of uncertainties are many, then a method is needed for assessing vulnerability and damage state appropriately. This study aims not only to present the way for finding fragility curve of structures by using universal structural analysis program and general probability density function but also to compare seismic isolation performance.

아파트단지내 조경시설물 평가에 관한 연구 : 수원 매탄5단지를 사례로 A Case Study of Maetan Apartment Complex in Suwon, Korea

김학범,김정태,임형준 안성산업대학교 2002 論文集 Vol.34 No.-

This study aims to provide useful data for designing the outdoor space or planning landscape architecture facilities in apartment housing complex. Primary data were collected by questionnaire survey in Maetan Apartment Complex in Suwon. The questionnaires contain three sets of variables : outdoor environment, landscape architecture facilities, and the respondents' demographic variables. The results are as follows. 1) The apartment residents are using bench or pergola most frequently among the landscape architecture related facilities. 2) The residents are dissatisfied with shortage of parking lots, therefore, more parking area is needed in the apartment complex. 3) The residents expressed considerable concern for trees, however, they pointed out to change some species of trees and need some professional management for them. 4) The variables related landscape architecture facilities were reduced to 6 factors; 'trees', 'bench/pergola', 'excercise/playground', 'pavement', 'lighting facility', 'parking lots'. And 'trees' is perceived the most important factor by the residents. 5) Finally, 'landscape architecture facilities', is most important factor among variables consist of apartment exterior environment.