중등도 및 중증고혈압에서 Nifedipine 설하투여의 강압효과에 관한 연구

김영훈,서순규,최인석,김열홍,안희권,심완주,노영무 대한내과학회 1986 대한내과학회지 Vol.31 No.5

In order to assess the efficacy of sublingual nifedipine in the acute treatment of moderate to severe hypertension, a single blind test was done in 30 patients, 10 males and 20 females, aged 40 to 76 years, with moderate to severe hypertension. The patients with mean sitting blood pressure(BP) of more than J40 mmHg received sublingual placebo, and BP and pulse rate(PR) were measured in sitting position 10,20 and 30 minutes after the sublingual placebo was given. The patients with post-placebo 30 minutes sitting mean BP of less than 13pmmHg were excluded from the study. The placebo treatment period was followed by the administration of 10mg of sublingual nifedipine, and BP and PR were measured 10,20,30 and 45 minutes after nifedipine was given. BP decreased with placebo treatment(p$lt;0. 01 by paired t-test, preplacebo vs. post-placebo 30 minutes). With sublingual nifedipine BP started to fall in 10 minutes and reached the lowest levels in 30 or 45 minu1es. The systolic BP decreased from 198.0±21.4mmHg to 159±20.4mmHg, diastolic BP from 122.5±13.0 mmHg to 103.2±14.4 mmHg and mean from 147.7±13.4 mmHg to 121.7±14.8 mmHg 45minutes after nifedipine(p$lt;0.01 by paired t-test). The average fall in systolic BP/diastolic BP/mean BP 45 minutes after nifedipine was 39/19/26 mmHg(p$lt;0. 001, by paired t-test). The maximal fall in systolic BP correlated better with pretreatment value(r=0.42) than the maximal fall in diastolic pressure(r=0.21), PR increased from 79±12 to 87±11/minute with nifedipine(p$lt;0.001, by paired t-test). Side effects were mild facial flushing(16.7%) and palpitation (3.3%). The findings suggest that a dose of 10mg of sublingual nifedipine is a simple, effective and safe method for the acute treatment of moderate to severe hypertension and can be used as a non-injecting alternative agent for the treatment of hypertensive emergency.

당뇨성망막증에서의 방사성핵종 망막신티그라피의 이용에 관한 연구

이상우,박영태,이형호,최승환,안일민,서순규,진용한,이태수 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.1

정신치료와 세계관

서동혁,이부영 한국분석심리학회 1988 心性硏究 Vol.3 No.1

B . C . G 접종후 속발된 심상성 낭창양 (狼瘡樣) 반응의 1 예

송준영,서정희 대한피부과학회 1979 大韓皮膚科學會誌 Vol.17 No.1

B.C.G. is a living attenuated vaccine which produces resistance to tuberculous infection. Until now, several million persons were vaccinated with B.C.G., the rnajority being between 7 and 14 years of age. A very small number of general fatal reaction have been reported but from an epidemiological view point this does not; serions dirninish. the importance of B.C.G. Vaccination in the fight against tubereulosis. Dermatological complication of R.C.G. are rarely seen. Specific reactions attributed to the Vaccination were excessive lymphadenitis, scrofuloderma like, Iupus vuIgaria like, lichen nitidus lesion and tuberculid type lesion. Non specific reactions include toxicoderma hemorrhagica, urticaria, erythema multiform, erythema nodosum and granuloma anulare. Literature was briefly reviewed comparision of clinical and histological findings with this particular case. We are going to report one case of lupus vulgaris like reaction after B.C.G. Vaccination.

BLT (Bi3.25La0.75Ti3O12) 박막의 결정립 배향성이 잔류 분극과 누설 전류에 미치는 영향

서주형,오상호,박찬향 대한금속재료학회(대한금속학회) 2001 대한금속·재료학회지 Vol.39 No.11

Effect of grain orientation on the electrical polarization and leakage current characteristics of Bi_(3.25)La_(0.75)Ti₃O_(12) (BLT) thin films was investigated in terms of c-axis off alignment. The c-axis epitaxial and various c-axis off aligned BLT films have been successfully grown by using different electrode materials (Pt and SrRuO₃) and heat-treatments. In order to evaluate the crystallinity and the film texture of various c-axis off-aligned BLT thin films, X-ray diffraction (XRD) and transmission electron microscopy (TEM) were carried out. BLT thin film grown on the SrRuO₃/SrTiO₃ (100) substrate revealed that its c-axis aligned completely parallel to the substrate normal, by developing cube-on-cube epitaxial relathionship with underlying SrRuO₃ film. The corresponding P-E curve showed nearly paraelectric property. The polycrystalline (117) and (014) oriented BLT films grown in this study were shown that their c-axis off alignment about growth direction increased by amount more than 50°. As the degree of c-axis off-alignment was increased, remanent polarization was increased due to the anisotropic polarization characteristic of BLT film, however, the surface roughness of BLT films was increased and it resulted in degraded leakage current characteristic. Therefore, grain orientation of BLT thin films is a crucial factor controlling the polarization properties and leakage current characteristics.

의학과 정신치료

서동혁,이부영 한국분석심리학회 1988 心性硏究 Vol.3 No.1

단섬유로 강화된 Nylon 6.6/Ionomer 복합재료의 물리적 특성

서광석,박광석,이철호 고려대학교 공학기술연구소 1999 공학논문집 Vol.37 No.1

Physical properties of short glass fiber-reinforced nylon 6,6 and ionomer (Surlyn 9020) composites were studied. While ionomer content was increased from 0 to 30phr, tensile strength and flexural strength were decreased, whereas impact strength had maximum value at 20phr. Permittivity, tans, and volume resistivity had no remarkable difference with the variation of ionomer content, In PEA (Pulsed electroacoustic) experiments, for moisture-free specimens, homocharges were accumulated near electrodes and increased with the increase of ionomer content up to 20phr. It was found that moisture uptake rate of nylon 6,6 was declined due to hydrophobicity of ionomer. For moisture-contained specimens, homocharges were increased with moisture content at first, and then decreased while moisture content saturated. Moisture-ionomer interaction was a major mechanism of homocharge formation.

저밀도 폴리에틸렌의 전기전도에 미치는 실리콘유의 영향

서광석,이창용,강창균 고려대학교 공학기술연구소 1991 고려대학교 생산기술연구소 생기연논문집 Vol.27 No.1

Electrical conduction characteristics of low density polyethylene with a silicon-oil layer at the surface have been investigated at medium fields ranging from about 75 to 650 ㎸/㎝ over the temperature range of 20 to 100℃. The conduction current of polyethylene increases exponentially with the electric field and gets higher as the temperature increases. The observed conduction behavior was explained in term of the SCLC and tunneling effect. Activation energy ranges from 0.54 to 0.44 eV over the field range of 90∼450 ㎸/㎝ and the charge mobility was estimated from a Child law to be in the order of 10^(-16)∼10^(-14)㎡/V·s. Silicone oil layer modifies the conduction behaviors in polyethylene. Major changes are (1) an increase in conduction currents, (2) a suppression in a rate of change of conduction currents, and (3) a decrease in activation energy.

최근 9 년간 ( 1966 - 1975 ) 피부과 입원 환자의 통계적 관찰

김윤원,서정희,송준원 대한피부과학회 1976 大韓皮膚科學會誌 Vol.14 No.1

A statisticaI and comparative observations were made on 141 in-patients and 84,269 out-patients in the department of dermatology, Presbyterian Hospital, Taegu, Korea during the period from August 1, 1966 to August 31, 1975

Keratinophilic Fungi 의 분리방법에 관한 연구

서치균 대한피부과학회 1966 대한피부과학회지 Vol.5 No.1

There are innumerable known and unknown fungi which inhabit soil, from which the causative organisms of deep mycoses have been isolated from many years, so that the concept of the role of soil as a reservoir of pathogenic fungi has received strong support. but the keratinophilic fungi which are capable of causing superficial dermatomycoses have only recently been isolated. Even though there arc both the membrane filter method and the direct culture method for isolating the keratinophilic fungi from soil, it is extremely difficult to isolate these fungi because there are so many saprophytes which cause contamination. However, in 1%2, Vanbreuseghem developed a selective method for isolating keratinophilic fungi from soil which is known as the hair-baiting technique. By means of this technique, the new species of K. ajelloi and M. cookei including the previous1y 1 known M. gypseum have heen obtained by many workers, and these fungi have been found to he world-wide in distribution. Some other species of keratinophilic fungi were also isolated in a few different countries. Since human hair was used as bait by Vanbreuseghem in his technique, it has been used widely by many workers, Up to the present time little research has been done in this field about evaluating or comparing the various keratinaceous materials other than human hair as bait. The author studied different kinds of keratinaceous materials from various sources to compare the difference in with a view to finding a The fungi used were of the growth of the keratinophilic fungi. These studies were done more ideal bait for the isolation of the keratinophilic fungi. 5 different species of M. gypseum, M.cookei, K. ajelloi, M. vanbreuseghemii, and M. canis. The baiting materials were human scalp hairs from 6 different age groups and axillary and pubic hairs from 2 different age groups of both sexes, 11 different domestic animal hairs, and 2 kinds of birds feathers. Horns and hoofs of cattle, pig hoofs and human nails as well as same corn husks, rice and barley stalks, and barks and leaves of some trees were also used as baiting materials. By the results of experiments with each. fungal species baited with each material, the author chose the better baiting materials composed of horn and hoof of cattle, pig hoof, human nail, body and tail hairs of horse, beard and tail:: hairs of black goat, body and tail hairs of dog, female pubic hairs of 20 to 25 year age group, and male scalp hairs of 55 to 60 year age group in equal parts to see the growth of fungi in natural soil. These were compared with the poorer baiting materials of body and tail hairs of guinea-pig, cat, and rabbit; body hair of mouse, chicken feather, and female axillary hair of 20 to 25 year age group.