정상교합자와 골격성 Ⅲ급 부정교합자의 저작운동형태의 비교

성기혁,성재현 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.5

정상교합자와 골격성 Ⅲ급 부정교합자의 저작운동형태를 비교연구하기위해서 30명의 정상교합자와 20명의 골격성Ⅲ급 부정교합자를 대상으로 츄잉검을 사용하고 BioPAK system을 이용하여 전두면상에서 저작운동을 기록, 분석하였다. 각 개체마다 대표하는 저작경로를 정하여 저작폭경, 개구거리, 개구각, 폐구각, 최대개구속도, 최대폐구속도를 알아보았다. 또 저작경로의 형태에 따라 특징적인 7가지 패턴으로 분류하여 다음의 결과를 얻었다. 1. 정상교합자군에 비해 골격성Ⅲ급 부정교합자군에서는 좀 더 다양하고 수직적인 저작양상을 나타내었다. 2. 저작폭경의 비교에서는 골격성Ⅲ급 부정교합자군이 정상교합자군에 비해 더 좁게 나타났다(P<0.01). 3. 개구거리에서는 골격성Ⅲ급 부정교합자군이 정상교합자군에 비해 더 작게 나타났으나 통계학적으로 유의성은 없었다(P>0.05). 4. 개구각과 폐구각에서는 골격성Ⅲ급 부정교합자군에서 정상교합자군보다 더욱 예각으로 나타났다(P<0.01). 5. 최대개구속도, 최대폐구속도에서는 정상교합자군에 비해 골격성Ⅲ급 부정교합자군에서 느리게 나타났으나 통계학적으로 유의성은 없었다(P>0.05). 6. 저작운동형태에 따른 분류에서 정상교합자군에서는 Type Ⅱ가 73.4%로 가장 많은 비율을 차지하였으나 골격성 Ⅲ급 부정교합자군에서는 Type Ⅲ가 35.0%, Type Ⅱ가 30.0%로 많은 비율을 차지하였다. 7. 저작운동형태에 따른 분류에서 골격성 Ⅲ급 부정교합자군에서는 Type Ⅳ(chopping type)가 25.0%로 정상교합자군 3.3%에 비해 많은 비율을 차지하였다. A comparative study was made on the chewing movements of normal occlusion and skeletal classⅢ malocclusion. Thirty normal occlusion subjects and twenty skeletal classⅢ malocclusion patients were given chewing gums for the study ; using BioPAK system, the chewing movement on the frontal plane was recorded and analyzed. With a typical chewing path chosen representing each subject, chewing width, opening distance, opening and closing angle, maximum opening and closing velocities were observed. Seven characteristic patterns were classified based on the types of chewing paths. The followings are the results: 1. Compared with the normal occlusion group, the skeletal classⅢ malocclusion group showed more varied and vertical chewing patterns. 2. In comparision of chewing widths, skeletal classⅢ malocclusion group showed narrower path than the normal occlusion group(P<0.01). 3. In opening distance, skeletal classⅢ malocclusion group appeared shorter than the normal occlusion group without statistical significance(P>0.05). 4. In opening and closing angles, skeletal classⅢ malocclusion group showed more acute angles than the normal occlusion group(P<0.01). 5. In maximum opening and closing velocities, skeletal classⅢ malocclusion group was slower than the normal occlusion group but with no statistical significance(P>0.05). 6. In the classification of chewing movement pattern, the normal occlusion group had TypeⅡ as the highest rate at 73.4%; in skeletal classⅢ malocclusion group, the highest rate was TypeⅢ at 35.0%, followed by TypeⅡ at 30.0%. 7. In the classification of chewing movement pattern, Type IV(chopping type) of skeletal classⅢ malocclusion group showed a higher rate with 25.0% over 3.3% of normal occlusion group.

韓國 Drosophila 屬內 16種에 對한 遺傳的 近緣關係

成耆昌,서민철,金源澤,金溶聲 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2

Eleven allozymes from sixteen species of Drosophila were analyzed by using horizontal starch gel electrophoresis in order to estimate genetic relationship among these species. All eleven allozymes were present in all sixteen species examined, and some commom alleles were also detected. The mean genetic identity between inter-and intra-subgenus Drosophila were estimated to be 0.16∼0.20, and 0.24∼0.28, respectively. The results showed that D. nigromaculata, which belongs to subgenus Drosophila, had closer genetic relationship to the species in subgenus Sophophora than to Drosophila. High mean genetic identity was also observed between subgenus Hirtodrosophila and Drosophila, and between subgenus Paradrosophila and Sophophora. Results of Nei's genetic identity test of the present data generally agreed with the previously known Drosophila classification establised based on the cytological and morphological characteristics.

새로운 5,6-dihydro-2-trifluoromethyl-1,4-oxathiincarboxanilide 유도체의 항균활성에 미치는 치환-phenylcarbamoyl group의 영향

성낙도,유성재,남기달,장기혁,한호규 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

기질(S) 화합물로 30종의 5,6-dihydro-2-trifluoromethyl-1,4-oxathiin carboxanilide 유도체들을 합성하고 벼 잎집무늬 마름병균(Rhizoctonia solani)과 밀 붉은 녹병균(Puccinia recondita)에 대한 항균활성(in vivo) 값(pI_50)을 측정하였다. (S)는 잘록병균보다 밀 붉은녹병균에 대하여 보다 큰 항균활성을 나타내었으며 두 종의 균에 대하여 3-methoxy, 11, 3-iso-propyloxy, 13 및 3-iso-propyl 치환체, 25가 제일 큰 활성을 보였다. 그리고 치환(X)-phenylcarbamoyl group의 변화에 따른 물리-화학 파라미터와 항균활성(pI_50)으로부터 구조-활성관계(SAR)를 검토 한 결과, 벼 잎집무늬 마름병균에 대하여는 공명효과에 따른 전자밀게(R<0)의 소수성이 큰(π>0) m-alkyl 치환기(X)가, 그리고 밀 붉은녹병균에 대하여는 분자 분극율(Sp.Po1.)과 분자의 음하전(ABSQ<0)을 위시하여 HOMO에너지(e.v.)가 클수록(HOMO<0) 높은 항균활성을 나타내었다. 또한, 전하-조절 반응에 의한 수용체-(S)간의 상호작용과 높은 활성발현 조건들이 검토되었다.(1998년 2월 3일 접수, 1998년 12월 1일 수리) New thirty derivatives of 5,6-dihydro-2-trifluoromethyl-1,4-oxathiin carboxanilide as substrate(S) were synthesized and their fungicidal activities in vivo against rice sheath blight(Rhizoctonia solani) and wheat leaf rust(Puccinia recondita) were examined. The structure activity relationships(SAR) between the activities(pI_50) and a physicochemical parameters of substituents(X) at the phenylcarbamoyl group were analyzed using the adaptive regression analysis method. The 3-methoxy, 11, 3-isopropyloxy, 13 and 3-isopropyl substituent, 25 as X on the phenylcarbamoyl group exhibited the most highest fungicidal activity against the two fungi. The fungicidal potency of the (S) against Puccinia recondita was higher than Rhizoctonia solani. In case of Rhizoctonia solani, the molecular hydrophobicity(π>0) and resonance effect(R<0) by meta-alkyl substitutents with electron donating were important factors in determining fungicidal activity. And the HOMO energy(HOMO>0), ABSQ, sum of absolute values of the atomic charges on each atom and specific polarizability(Sp.Pol<0) of (S) were significantly influential towards fungicidal activity against Puccinia recondita. The interaction between (S) and receptor against from the based on SAR studies proceeds through charge-control reaction, and conditions to show higher activity has been also discussed.

기저세포암, 피부전이암과 유사한 조직소견을 보인 안검 외 피지선암 1예

김상태,노효진,서기석 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

Backgroud : Extraocular sebaceous carcinoma is a malignant tumor derived from the adnexal epithelium of sebaceous glands. A poorly differentiated sebaceous carcinoma shows variable histopathologic findings and mimics other primary tumor and cutaneous metastases mostly composed of clear cells. Case : Our patient consultation was requested for a 53 year?old female with solitary mild painful tumor on the scalp. The first histopathlogic impression of this case was basal cell carcinoma on the other hospital. After reevaluation, our diagnosis is not basal cell carcinoma but extraocular sebaceous carcinoma. Conclusion : A thorough exact recognition of characteristic histopathologic features of extraocular sebaceous carcinoma is necessary for making diagnosis, treatment plan and determining the prognosis.

Drosophila melanogaster 韓國 自然集團에 있어서 P-M system에 依據한 系統型 轉換

成耆昌,崔喜慶,金溶聲 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.1

Isofemale lines of Drosophila melanogaster were established from Daejon in Korea and were examined in order to investigate the changes of cytotype or strain type by P-M system through 1∼15 generations. The results are as follows: 1. Using π_2 (strong P) strains and bw;st (true M) strains as standard strains, the mean sterility frequencies from Cross A were 20.8%∼34.6% for each generations and the mean sterility frequencies from Cross B were 0.0%∼0.3%. 2. Frequency of strain with P cytotype for each generation was analyzed to be 44.8%(G₁), 59.2%(G₂), 43.7%(G₄), 36.7%(G_7), 29.2%(G_10) and 36.7%(G_15). Therefore it was tend to be low as increased with generation number, but the differencies in percentage of GD sterility between each generation are non-significant statistically. 3. Among the isofemale lines, type conversions were observed. Q→M', M'→Q and M'→M changes have occured with frequency of 18.4%, 8.2% and 4.1%, respectively. The remaining lines (69.3%) were unchanged through several generations. 4. The results suggest that Drosophila melanogaster are appeared temporally as a certain strain type in natural population, but the type conversions were represented by interactions between P elements in each genome and cytoplasm for each generation.

Drosophila busckii의 韓國集團에서 있어서 同位酵素 多形現象

成耆昌,尙椿植,金彧,金大鎰 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.1

Genetic structure and variability were investigated in four Korean populations of Drosophila busckii. Eight allozyme loci were analysed by means of starch gel electrophoresis. The proportions of polymorphic loci and loci heterozygous per individual were estimated to be 0.25 and 0.051, respectively. The average genetic similarity between four populations was found to be S―=0.977. This value is similar to the other Drosophila populations reported. However, the gene variation of D. busckii in this study appeared to be the least variable among 28 Drosophila species reported. It is suggested that the low gene variation in D. busckii might be due to adaptation of this species to a narrow niche, but the possibility of occurrence of the random drift cannot be excluded.

韓國人 指紋型의 遺傳學的 分析

成耆昌,李起俊 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.2

The finger print pattern of the Korean population has been examined. The predominant finger print type of non-criminal population consisted of 49% Loop type, 45.5% Whorl type, 2.6% Simple arch and 2.5% Tented arch. Among criminal populations, the frequency of occurance of finger print types was found to be 52.2% Loop type, 40.9% Whorl type, 2.5% Tented arch, and 2.8% Simple arch respectively. In addition, criminal population contained 0.3% Accidental type, which was absent in non-criminal population. The total Ridge Number for the non-criminals was 151 for females and 143 for males, while in criminal population it was 127 for females and 138 for males. The atd angle for non-criminal population was 82.29° for males and 83.38° for females. The a-b ridge number was found to be 76.05 for males and 73.24 for females.

Drosophila melanogaster 韓國 自然集團에 있어서 P-M System에 依據한 Cytotype 分布 硏究

成耆昌,安成晥 성균관대학교 기초과학연구소 1988 論文集 Vol.39 No.1

Hybrid dysgenesis, aberrant phenomena, found in certain interstrain hybrids of Drosophila melanogaster, is caused by the interaction of chromosomal and cytoplasmic factors. 10 natural populations of D. melanogaster from Korea were investigated in order to determine the distribution of P factor and M cytotype, two components of P-M system. The results showed that: 1) The P factor activity for potential GD sterility is absent or present at only very low frequencies in these populations. 2) All locations show rather similar distributions, indicating weak M cytotype. The levels of activity of M cytotype were appeared to be variable among 10 populations. 3) Q cytotype, which cause immune to the P factor, was found at high frequencies in these populations. 4) The results seem to suggest that polymorphism of M and Q cytotype exists in Korean natural population.

서비스 무역의 공급형태와 통계

기성래 조선대학교 지역사회발전연구원 2001 地域發展硏究 Vol.5 No.2

韓國 노랑초파리의 自然集團에 있어서 P elements의 分布에 관한 硏究

成耆昌,金滿在,金溶聲 성균관대학교 기초과학연구소 1988 論文集 Vol.39 No.2

Isofemale lines of Drosophila melanogaster were established from Moonsan and Osan, Korea and were tested for GD sterility. The results are as follows; 1. Using π_2 (strong P) strain and Canton-S (true M) strain as a standard strains, the frequencies of P cytotype for all isofemale lines were 37.7% (Moonsan) and 56.5%(Osan), but the activities of P factor very low. 2. The distributions of strain types by Kidwell were 62.3%, 43.5% for M' (pseudo-M) strain, and 37.7%, 56.5% for Q (weak P) strain in Moonsan and Osan, respectively. Thus, it was appeared that these populations are consisted of M' and Q strains. 3. The results suggested that the activities of P elements were regulated by their P cytotypes though the potentialities of P activity were present in these populations.